Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09445 | 31746151 | Adv Healthc Mater | In Vitro Human Liver Model of Nonalcoholic Steatohepatitis by Coculturing Hepatocytes, Endothelial Cells, and Kupffer Cells. | 2019 | Details |
| A09447 | 31745030 | Indian J Med Microbiol | Gut microbiota and its mysteries. | 2020 | Details |
| A09449 | 31744059 | Mar Drugs | Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice. | 2019 | Details |
| A09452 | 31742330 | Glycobiology | Modulation of hepatocyte sialylation drives spontaneous fatty liver disease and inflammation. | 2020 | Details |
| A09465 | 31734402 | Autoimmun Rev | Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies. | 2019 | Details |
| A09473 | 31731005 | Contemp Clin Trials | A randomized, double-blind, multicenter, phase 2b study to evaluate the safety and efficacy of a combination of tropifexor and cenicriviroc in patients with nonalcoholic steatohepatitis and liver fibrosis: Study design of the TANDEM trial. | 2019 | Details |
| A09480 | 31728041 | Sci Rep | Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism. | 2019 | Details |
| A09485 | 31726747 | Diseases | Role of Gut Dysbiosis in Liver Diseases: What Have We Learned So Far? | 2019 | Details |
| A09488 | 31726115 | J Hepatol | A defect in endothelial autophagy occurs in patients with non-alcoholic steatohepatitis and promotes inflammation and fibrosis. | 2019 | Details |
| A09502 | 31717860 | Cells | The Role of Gut-Derived Microbial Antigens on Liver Fibrosis Initiation and Progression. | 2019 | Details |
| A09503 | 31717842 | Nutrients | Efficacy and Mechanism of Polymerized Anthocyanin from Grape-Skin Extract on High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09509 | 31717261 | Nutrients | Curcumin Ameliorates Nonalcoholic Fatty Liver Disease through Inhibition of O-GlcNAcylation. | 2019 | Details |
| A09514 | 31714387 | Eur J Gastroenterol Hepatol | Helicobacter pylori infection may increase the severity of nonalcoholic fatty liver disease via promoting liver function damage, glycometabolism, lipid metabolism, inflammatory reaction and metabolic syndrome. | 2020 | Details |
| A09527 | 31707624 | Rev Endocr Metab Disord | Dietary lipids, gut microbiota and lipid metabolism. | 2019 | Details |
| A09530 | 31706246 | Environ Toxicol Pharmacol | Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis. | 2019 | Details |
| A09534 | 31705800 | Hepatology | Interleukin-22 Ameliorates Neutrophil-Driven Nonalcoholic Steatohepatitis Through Multiple Targets. | 2020 | Details |
| A09542 | 31701087 | Nat Metab | Transcriptional Network Analysis Implicates Altered Hepatic Immune Function in NASH development and resolution. | 2019 | Details |
| A09551 | 31696774 | Gut Microbes | Lower gut microbiome diversity and higher abundance of proinflammatory genus Collinsella are associated with biopsy-proven nonalcoholic steatohepatitis. | 2019 | Details |
| A09557 | 31695251 | J Clin Exp Hepatol | Molecular and Pathological Events Involved in the Pathogenesis of Diabetes-Associated Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A09567 | 31692530 | Pediatric Health Med Ther | Pediatric non-alcoholic fatty liver disease: current perspectives on diagnosis and management. | 2019 | Details |
| A09568 | 31692390 | Expert Rev Gastroenterol Hepatol | Progress in promising anti-fibrotic therapies. | 2019 | Details |
| A09575 | 31689910 | Nutrients | The Role of Probiotics in Nonalcoholic Fatty Liver Disease: A New Insight into Therapeutic Strategies. | 2019 | Details |
| A09576 | 31689883 | Foods | Agaricus brasiliensis KA21 May Prevent Diet-Induced Nash Through Its Antioxidant, Anti-Inflammatory, and Anti-Fibrotic Activities in the Liver. | 2019 | Details |
| A09578 | 31689560 | Cell Mol Gastroenterol Hepatol | A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target. | 2019 | Details |
| A09581 | 31688305 | Eur J Gastroenterol Hepatol | Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A09594 | 31682518 | Endocr Pract | CLINICAL PRACTICE GUIDELINES FOR THE PERIOPERATIVE NUTRITION, METABOLIC, AND NONSURGICAL SUPPORT OF PATIENTS UNDERGOING BARIATRIC PROCEDURES - 2019 UPDATE: COSPONSORED BY AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY, THE OBESITY SOCIETY, AMERICAN SOCIETY FOR METABOLIC & BARIATRIC SURGERY, OBESITY MEDICINE ASSOCIATION, AND AMERICAN SOCIETY OF ANESTHESIOLOGISTS - EXECUTIVE SUMMARY. | 2019 | Details |
| A09596 | 31682309 | J Dig Dis | Development of new drugs for the treatment of nonalcoholic steatohepatitis. | 2019 | Details |
| A09602 | 31678261 | Food Chem Toxicol | Cigarette smoking differentially regulates inflammatory responses in a mouse model of nonalcoholic steatohepatitis depending on exposure time point. | 2019 | Details |
| A09618 | 31673534 | Hepatobiliary Surg Nutr | Endogenously increased n-3 PUFA levels in fat-1 transgenic mice do not protect from non-alcoholic steatohepatitis. | 2019 | Details |
| A09619 | 31672578 | Life Sci | Amlexanox reversed non-alcoholic fatty liver disease through IKKε inhibition of hepatic stellate cell. | 2019 | Details |
| A09625 | 31670498 | Panminerva Med | Liver disease and heart failure. | 2019 | Details |
| A09642 | 31661783 | Metabolites | A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice. | 2019 | Details |
| A09651 | 31658321 | Rom J Morphol Embryol | Thymoquinone reverses nonalcoholic fatty liver disease (NAFLD) associated with experimental hypothyroidism. | 2019 | Details |
| A09658 | 31656991 | Rev Endocr Metab Disord | Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease. | 2019 | Details |
| A09668 | 31652837 | Cancers (Basel) | Deregulated Lysophosphatidic Acid Metabolism and Signaling in Liver Cancer. | 2019 | Details |
| A09671 | 31652578 | Int J Mol Sci | The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma. | 2019 | Details |
| A09691 | 31645988 | BMJ Open Gastroenterol | Relationship between Streptococcus mutans expressing Cnm in the oral cavity and non-alcoholic steatohepatitis: a pilot study. | 2019 | Details |
| A09707 | 31638172 | Int J Mol Med | The A3 adenosine receptor agonist, namodenoson, ameliorates non‑alcoholic steatohepatitis in mice. | 2019 | Details |
| A09712 | 31636851 | Toxicol Res | Theracurmin (Highly Bioavailable Curcumin) Prevents High Fat Diet-Induced Hepatic Steatosis Development in Mice. | 2019 | Details |
| A09715 | 31635468 | Vnitr Lek | Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A09722 | 31634046 | J Med Food | Oral Administration of Hoodia parviflora Alleviates Insulin Resistance and Nonalcoholic Steatohepatitis. | 2019 | Details |
| A09743 | 31629366 | Endocr Rev | Nonalcoholic Fatty Liver Disease in Adults: Current Concepts in Etiology, Outcomes, and Management. | 2020 | Details |
| A09756 | 31622986 | Exp Clin Endocrinol Diabetes | Exogenous Hydrogen Sulfide Alleviates-Induced Intracellular Inflammation in HepG2 Cells. | 2019 | Details |
| A09757 | 31622696 | J Hepatol | The gut-liver axis in liver disease: Pathophysiological basis for therapy. | 2019 | Details |
| A09758 | 31622581 | Am J Med | Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction in Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09760 | 31621579 | Elife | Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. | 2019 | Details |
| A09763 | 31620616 | Yeungnam Univ J Med | Pharmacologic therapy for nonalcoholic steatohepatitis focusing on pathophysiology. | 2019 | Details |
| A09764 | 31619310 | Br J Nutr | Association between edible mushroom intake and the prevalence of newly diagnosed non-alcoholic fatty liver disease: results from the Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study in China. | 2020 | Details |
| A09774 | 31614690 | Int J Mol Sci | Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence. | 2019 | Details |
| A09778 | 31614590 | Int J Mol Sci | Liver X Receptors Regulate Cholesterol Metabolism and Immunity in Hepatic Nonparenchymal Cells. | 2019 | Details |
| A09794 | 31608220 | J Clin Transl Hepatol | Obesity Paradox in Chronic Liver Diseases: Product of Bias or a Real Thing? | 2019 | Details |
| A09809 | 31602167 | World J Gastroenterol | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history. | 2019 | Details |
| A09811 | 31601229 | Trials | Effect of probiotic supplementation in nonalcoholic steatohepatitis patients: PROBILIVER TRIAL protocol. | 2019 | Details |
| A09817 | 31599445 | Eur Rev Med Pharmacol Sci | Cardiolipin inhibitor ameliorates the non-alcoholic steatohepatitis through suppressing NLRP3 inflammasome activation. | 2019 | Details |
| A09827 | 31597406 | Cells | A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A09834 | 31595236 | Porto Biomed J | Dietary cholesterol does not break your heart but kills your liver. | 2019 | Details |
| A09835 | 31595205 | Aging Dis | Pyroptosis in Liver Disease: New Insights into Disease Mechanisms. | 2019 | Details |
| A09842 | 31593687 | Eur J Pharmacol | Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy. | 2019 | Details |
| A09853 | 31591383 | Cell Death Dis | Progranulin attenuates liver fibrosis by downregulating the inflammatory response. | 2019 | Details |
| A09856 | 31590120 | Curr Opin Pharmacol | New and emerging anti-fibrotic therapeutics entering or already in clinical trials in chronic liver diseases. | 2019 | Details |
| A09859 | 31589122 | Curr Drug Targets | Natural Aldose Reductase Inhibitor: A Potential Therapeutic Agent for Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A09877 | 30687796 | Wellcome Open Res | Metabolic profiling of adolescent non-alcoholic fatty liver disease. | 2019 | Details |
| A09878 | 31577913 | FASEB J | Imaging inflammation and its resolution in health and disease: current status, clinical needs, challenges, and opportunities. | 2019 | Details |
| A09886 | 31574533 | Carcinogenesis | Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation. | 2020 | Details |
| A09888 | 31574193 | Mol Nutr Food Res | Green Tea Extract Treatment in Obese Mice with Nonalcoholic Steatohepatitis Restores the Hepatic Metabolome in Association with Limiting Endotoxemia-TLR4-NFκB-Mediated Inflammation. | 2019 | Details |
| A09892 | 31572482 | Arch Med Sci | Effect of Lactobacillus paracasei N1115 and fructooligosaccharides in nonalcoholic fatty liver disease. | 2019 | Details |
| A09899 | 31568800 | J Hepatol | Hepatocyte-derived extracellular vesicles promote endothelial inflammation and atherogenesis via microRNA-1. | 2019 | Details |
| A09914 | 31562717 | J Assoc Physicians India | Development of Non-alcoholic Fatty Liver Disease (NAFLD) in Young Obese Tribal Subjects of Tripura: Link between Low 25 (OH) Vitamin-D Levels and Immune Modulators. | 2019 | Details |
| A09919 | 31560040 | Inflamm Bowel Dis | Onset of Ulcerative Colitis in a Patient with Nonalcoholic Fatty Liver Disease (NAFLD): Dramatic Effect of Plant-based Diet for NAFLD. | 2019 | Details |
| A09923 | 31558861 | World J Gastroenterol | Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways. | 2019 | Details |
| A09932 | 31555219 | Front Endocrinol (Lausanne) | Gut Dysfunction and Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09934 | 31554528 | Br J Nutr | Randomised trial of chronic supplementation with a nutraceutical mixture in subjects with non-alcoholic fatty liver disease. | 2020 | Details |
| A09939 | 31553663 | Am J Physiol Regul Integr Comp Physiol | Sex modifies the consequences of extended fructose consumption on liver health, motor function, and physiological damage in rats. | 2019 | Details |
| A09941 | 31551937 | Front Endocrinol (Lausanne) | Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring Rats. | 2019 | Details |
| A09944 | 31551213 | Pak J Pharm Sci | Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients. | 2019 | Details |
| A09950 | 31547124 | J Clin Med | Is There a Link between Basal Metabolic Rate, Spleen Volume and Hepatic Growth Factor Levels in Patients with Obesity-Related NAFLD? | 2019 | Details |
| A09966 | 31541796 | Phytomedicine | Hepatoprotective and anti-inflammatory effects of total flavonoids of Qu Zhi Ke (peel of Citrus changshan-huyou) on non-alcoholic fatty liver disease in rats via modulation of NF-κB and MAPKs. | 2019 | Details |
| A09998 | 31531097 | Iran J Pathol | The Correlation between Serum Zinc Level and Liver Histology in Non-Alcoholic Steatohepatitis. | 2018 | Details |
| A10001 | 31530714 | Gut | Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells. | 2019 | Details |
| A10009 | 31526528 | J Pediatr | The Contribution of the Adipose Tissue-Liver Axis in Pediatric Patients with Nonalcoholic Fatty Liver Disease after Laparoscopic Sleeve Gastrectomy. | 2019 | Details |
| A10015 | 31523515 | PeerJ | Nicotinamide riboside exerts protective effect against aging-induced NAFLD-like hepatic dysfunction in mice. | 2019 | Details |
| A10020 | 31522189 | Am J Case Rep | Sugar and the Mosaic of Autoimmunity. | 2019 | Details |
| A10023 | 31521175 | Lipids Health Dis | Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities. | 2019 | Details |
| A10050 | 31514003 | Chemosphere | Transcriptome analysis in normal human liver cells exposed to 2, 3, 3', 4, 4', 5 - Hexachlorobiphenyl (PCB 156). | 2019 | Details |
| A10051 | 31512431 | Adv Gerontol | [The effect of high-dose metformin on the metabolic parameters and functional state of the liver of agouti-mice with the melanocortin obesity.] | 2019 | Details |
| A10053 | 31510105 | Cells | New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease. | 2019 | Details |
| A10056 | 31506976 | Hepatology | Vitamin D Receptor Activation in Liver Macrophages Ameliorates Hepatic Inflammation, Steatosis, and Insulin Resistance in Mice. | 2020 | Details |
| A10057 | 31506634 | Lab Invest | Automated computerized image analysis for the user-independent evaluation of disease severity in preclinical models of NAFLD/NASH. | 2019 | Details |
| A10058 | 31506421 | Exp Mol Med | Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats. | 2019 | Details |
| A10062 | 31505462 | J Endocrinol | Mice lacking adenosine 2A receptor reveal increased severity of MCD-induced NASH. | 2019 | Details |
| A10071 | 31503268 | Food Funct | Green tea extract inhibits early oncogenic responses in mice with nonalcoholic steatohepatitis. | 2019 | Details |
| A10074 | 31500354 | Cells | Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy. | 2019 | Details |
| A10078 | 31497742 | Hepatol Commun | Interleukin-32 Contributes to Human Nonalcoholic Fatty Liver Disease and Insulin Resistance. | 2019 | Details |
| A10092 | 31491513 | Int J Biol Macromol | MDG-1, an Ophiopogon polysaccharide, restrains process of non-alcoholic fatty liver disease via modulating the gut-liver axis. | 2019 | Details |
| A10095 | 31488310 | Rev Gastroenterol Mex (Engl Ed) | Extrahepatic complications of non-alcoholic fatty liver disease: Its impact beyond the liver. | 2019 | Details |
| A10098 | 31485221 | Int J Endocrinol | Compound C Protects Mice from HFD-Induced Obesity and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10099 | 31484323 | Nutrients | Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress. | 2019 | Details |
| A10110 | 31480575 | Biomolecules | Raw Bowl Tea (Tuocha) Polyphenol Prevention of Nonalcoholic Fatty Liver Disease by Regulating Intestinal Function in Mice. | 2019 | Details |
| A10112 | 31479282 | Expert Opin Drug Saf | The safety of anti-interleukins monoclonal antibodies for the treatment of psoriasis. | 2019 | Details |
| A10115 | 31477174 | Stem Cell Res Ther | Antioxidant-upregulated mesenchymal stem cells reduce inflammation and improve fatty liver disease in diet-induced obesity. | 2019 | Details |