Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A07791 | 32353589 | Pharmacol Res | 18β-Glycyrrhetinic acid acts through hepatocyte nuclear factor 4 alpha to modulate lipid and carbohydrate metabolism. | 2020 | Details |
| A07801 | 32351917 | Front Pediatr | Nonalcoholic Fatty Liver Disease Is Associated With Low Skeletal Muscle Mass in Overweight/Obese Youths. | 2020 | Details |
| A07805 | 32351030 | Pediatr Obes | The relationship between pancreas steatosis and the risk of metabolic syndrome and insulin resistance in Chinese adolescents with concurrent obesity and non-alcoholic fatty liver disease. | 2020 | Details |
| A07807 | 32350271 | Nat Commun | Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease. | 2020 | Details |
| A07814 | 32348835 | Life Sci | Exenatide ameliorates experimental non-alcoholic fatty liver in rats via suppression of toll-like receptor 4/NFκB signaling: Comparison to metformin. | 2020 | Details |
| A07816 | 32347583 | FASEB J | Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll-like 4 receptor signaling. | 2020 | Details |
| A07818 | 32346285 | Drug Des Devel Ther | Radix Polygoni Multiflori and Its Main Component Emodin Attenuate Non-Alcoholic Fatty Liver Disease in Zebrafish by Regulation of AMPK Signaling Pathway. | 2020 | Details |
| A07850 | 32335723 | Appl Microbiol Biotechnol | Lactobacillus plantarum NA136 ameliorates nonalcoholic fatty liver disease by modulating gut microbiota, improving intestinal barrier integrity, and attenuating inflammation. | 2020 | Details |
| A07857 | 32333362 | Indian J Gastroenterol | The effect of PNPLA3 polymorphism as gain in function mutation in the pathogenesis of non-alcoholic fatty liver disease. | 2020 | Details |
| A07868 | 32329579 | Liver Int | Occult hepatitis B virus infection predicts non-alcoholic steatohepatitis in severely obese individuals from Italy. | 2020 | Details |
| A07877 | 32325919 | Nutrients | Decreased Consumption of Added Fructose Reduces Waist Circumference and Blood Glucose Concentration in Patients with Overweight and Obesity. The DISFRUTE Study: A Randomised Trial in Primary Care. | 2020 | Details |
| A07882 | 32324317 | J Cell Mol Med | GRHL2 induces liver fibrosis and intestinal mucosal barrier dysfunction in non-alcoholic fatty liver disease via microRNA-200 and the MAPK pathway. | 2020 | Details |
| A07887 | 32322309 | Diabetol Metab Syndr | Effect of circulating exosomes derived from normal-weight and obese women on gluconeogenesis, glycogenesis, lipogenesis and secretion of FGF21 and fetuin A in HepG2 cells. | 2020 | Details |
| A07898 | 32317687 | Sci Rep | Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic steatohepatitis. | 2020 | Details |
| A07910 | 32314167 | Indian J Gastroenterol | Metabolic syndrome is not uncommon among lean non-alcoholic fatty liver disease patients as compared with those with obesity. | 2020 | Details |
| A07912 | 32312974 | Nat Commun | Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance. | 2020 | Details |
| A07917 | 32311490 | Free Radic Biol Med | Targeting DUSP7 signaling alleviates hepatic steatosis, inflammation and oxidative stress in high fat diet (HFD)-fed mice via suppression of TAK1. | 2020 | Details |
| A07922 | 32308060 | Free Radic Res | Emerging connections between oxidative stress, defective proteolysis, and metabolic diseases. | 2020 | Details |
| A07940 | 32304142 | FASEB J | Characterization of the variability in the extent of nonalcoholic fatty liver induced by a high-fat diet in the genetically diverse Collaborative Cross mouse model. | 2020 | Details |
| A07943 | 32303170 | Curr Pharm Des | Hepatoprotective Effects of Resveratrol in Non-Alcoholic Fatty Live Disease. | 2021 | Details |
| A07945 | 32303004 | Aging (Albany NY) | Ultraconserved element uc.333 increases insulin sensitivity by binding to miR-223. | 2020 | Details |
| A07947 | 32302728 | J Hepatol | Exercise retards hepatocarcinogenesis in obese mice independently of weight control. | 2020 | Details |
| A07979 | 32291277 | Diabetes Care | Effects of Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide on Biomarkers of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes. | 2020 | Details |
| A07980 | 32290942 | Wei Sheng Yan Jiu | [Effects of lycopene on metabolism of glycolipid and inflammation in non-alcoholic fatty liver disease rats]. | 2020 | Details |
| A07983 | 32290535 | Nutrients | Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases. | 2020 | Details |
| A07984 | 32290381 | Int J Environ Res Public Health | Sex Hormone-Dependent Physiology and Diseases of Liver. | 2020 | Details |
| A07991 | 32286882 | Am J Physiol Endocrinol Metab | HDL-apoA-I kinetics in response to 16 wk of exercise training in men with nonalcoholic fatty liver disease. | 2020 | Details |
| A07992 | 32285823 | Wiad Lek | Changes in the level of α1-antitrypsin in patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A07996 | 32284046 | Lipids Health Dis | Mutual interaction between endoplasmic reticulum and mitochondria in nonalcoholic fatty liver disease. | 2020 | Details |
| A08001 | 32283200 | Food Chem Toxicol | Impaired ferritinophagy flux induced by high fat diet mediates hepatic insulin resistance via endoplasmic reticulum stress. | 2020 | Details |
| A08006 | 32281563 | J Oleo Sci | Epigallocatechin Gallate Suppresses Inflammatory Responses by Inhibiting Toll-like Receptor 4 Signaling and Alleviates Insulin Resistance in the Livers of High-fat-diet Rats. | 2020 | Details |
| A08007 | 32281324 | Korean Circ J | A Close Relationship between Non-Alcoholic Fatty Liver Disease Marker and New-Onset Hypertension in Healthy Korean Adults. | 2020 | Details |
| A08015 | 32280254 | Diabetes Metab Syndr Obes | Low-Magnitude High-Frequency Vibration Decreases Body Weight Gain and Increases Muscle Strength by Enhancing the p38 and AMPK Pathways in db/db Mice. | 2020 | Details |
| A08026 | 32277923 | Mol Metab | Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model. | 2020 | Details |
| A08033 | 32274915 | Minerva Pediatr | Metabolic syndrome in children. | 2020 | Details |
| A08041 | 32272794 | Animals (Basel) | Identification of Crucial Genetic Factors, Such as PPARγ, that Regulate the Pathogenesis of Fatty Liver Disease in Dairy Cows Is Imperative for the Sustainable Development of Dairy Industry. | 2020 | Details |
| A08044 | 32271385 | J Clin Endocrinol Metab | Plasma BCAA Changes in Patients With NAFLD Are Sex Dependent. | 2020 | Details |
| A08046 | 32270583 | J Diabetes Investig | Increased risks of different grades of non-alcoholic fatty liver disease in prediabetic subjects with impaired fasting glucose and glucose tolerance, including the isolated glycosylated hemoglobin levels of 5.7-6.4% in a Chinese population. | 2020 | Details |
| A08053 | 32267638 | Ned Tijdschr Geneeskd | [Non-alcoholic fatty liver disease; a full-bodied epidemic]. | 2020 | Details |
| A08057 | 32266697 | Obes Surg | Sleeve Gastroplasty Combined with the NLRP3 Inflammasome Inhibitor CY-09 Reduces Body Weight, Improves Insulin Resistance and Alleviates Hepatic Steatosis in Mouse Model. | 2020 | Details |
| A08062 | 32259637 | Mol Cell Endocrinol | Anti-steatotic linagliptin pleiotropic effects encompasses suppression of de novo lipogenesis and ER stress in high-fat-fed mice. | 2020 | Details |
| A08065 | 32258945 | Hepatol Commun | Bile Acid Diarrhea and NAFLD: Shared Pathways for Distinct Phenotypes. | 2020 | Details |
| A08066 | 32258944 | Hepatol Commun | Pathogenesis of Nonalcoholic Steatohepatitis: An Overview. | 2020 | Details |
| A08070 | 32258522 | Transl Gastroenterol Hepatol | Peri-transplant renal dysfunction in patients with non-alcoholic steatohepatitis undergoing liver transplantation. | 2020 | Details |
| A08077 | 32256346 | Front Pharmacol | Hepatoprotective Effect of Cranberry Nutraceutical Extract in Non-alcoholic Fatty Liver Model in Rats: Impact on Insulin Resistance and Nrf-2 Expression. | 2020 | Details |
| A08083 | 32253813 | J Cell Mol Med | Enhanced liver but not muscle OXPHOS in diabetes and reduced glucose output by complex I inhibition. | 2020 | Details |
| A08088 | 32252024 | J Endocrinol | miR-188 promotes liver steatosis and insulin resistance via the autophagy pathway. | 2020 | Details |
| A08092 | 32250344 | J Clin Invest | Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice. | 2020 | Details |
| A08095 | 32247823 | J Hepatol | Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis. | 2020 | Details |
| A08097 | 32246876 | J Gastroenterol Hepatol | Development and validation of a novel non-invasive test for diagnosing fibrotic non-alcoholic steatohepatitis in patients with biopsy-proven non-alcoholic fatty liver disease. | 2020 | Details |
| A08100 | 32245619 | Biochem Biophys Res Commun | Humanin attenuates palmitate-induced hepatic lipid accumulation and insulin resistance via AMPK-mediated suppression of the mTOR pathway. | 2020 | Details |
| A08102 | 32245585 | Chin J Nat Med | Fatty liver diseases, mechanisms, and potential therapeutic plant medicines. | 2020 | Details |
| A08119 | 32240652 | Biochem Pharmacol | Pyrvinium pamoate attenuates non-alcoholic steatohepatitis: Insight on hedgehog/Gli and Wnt/β-catenin signaling crosstalk. | 2020 | Details |
| A08122 | 32239453 | Endocrine | Insulin resistance is related with liver fibrosis in type 2 diabetic patients with non-alcoholic fatty liver disease proven biopsy and Mediterranean diet pattern as a protective factor. | 2020 | Details |
| A08127 | 32237922 | Int J Food Sci Nutr | Combined cranberry supplementation and weight loss diet in non-alcoholic fatty liver disease: a double-blind placebo-controlled randomized clinical trial. | 2020 | Details |
| A08129 | 32237015 | Pediatr Diabetes | Associations of physical activity and fitness with hepatic steatosis, liver enzymes, and insulin resistance in children with overweight/obesity. | 2020 | Details |
| A08130 | 32235829 | Cell Death Dis | TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice. | 2020 | Details |
| A08132 | 32235601 | J Clin Med | Active Helicobacter pylori Infection is Independently Associated with Nonalcoholic Steatohepatitis in Morbidly Obese Patients. | 2020 | Details |
| A08136 | 32232972 | J Diabetes Investig | New perspective on type 2 diabetes, dyslipidemia and non-alcoholic fatty liver disease. | 2020 | Details |
| A08139 | 32231442 | Clin Med Insights Endocrinol Diabetes | Dipeptidyl Peptidase-4 at the Interface Between Inflammation and Metabolism. | 2020 | Details |
| A08140 | 32231437 | Diabetes Metab Syndr Obes | Dual SGLT1/SGLT2 Inhibitor Phlorizin Ameliorates Non-Alcoholic Fatty Liver Disease and Hepatic Glucose Production in Type 2 Diabetic Mice. | 2020 | Details |
| A08149 | 32228319 | Am J Physiol Endocrinol Metab | Downregulated microRNA-130b-5p prevents lipid accumulation and insulin resistance in a murine model of nonalcoholic fatty liver disease. | 2020 | Details |
| A08155 | 32225108 | Int J Mol Sci | Targeting of Secretory Proteins as a Therapeutic Strategy for Treatment of Nonalcoholic Steatohepatitis (NASH). | 2020 | Details |
| A08157 | 32223926 | Biochem Biophys Res Commun | Remdesivir attenuates high fat diet (HFD)-induced NAFLD by regulating hepatocyte dyslipidemia and inflammation via the suppression of STING. | 2020 | Details |
| A08158 | 32223569 | Arch Physiol Biochem | Crosstalk between kidney and liver in non-alcoholic fatty liver disease: mechanisms and therapeutic approaches. | 2020 | Details |
| A08162 | 32222944 | Indian J Gastroenterol | Correlation between insulin resistance and liver histology in patients with nonalcoholic steatohepatitis with and without obesity. | 2020 | Details |
| A08174 | 32218179 | Biomolecules | A Sweet Connection? Fructose's Role in Hepatocellular Carcinoma. | 2020 | Details |
| A08178 | 32217466 | J Nutr Biochem | The modulation of Luffa cylindrica (L.) Roem supplementation on gene expression and amino acid profiles in liver for alleviating hepatic steatosis via gut microbiota in high-fat diet-fed mice: insight from hepatic transcriptome analysis. | 2020 | Details |
| A08191 | 32212870 | Expert Rev Endocrinol Metab | Nonalcoholic fatty liver disease, insulin resistance, and sweeteners: a literature review. | 2020 | Details |
| A08194 | 32211252 | Cureus | Anthropometric Measurements and Lifestyle Characteristics of Individuals with Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A08195 | 32210914 | Front Endocrinol (Lausanne) | The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A08198 | 32209063 | BMC Public Health | Height predict incident non-alcoholic fatty liver disease among general adult population in Tianjin, China, independent of body mass index, waist circumference, waist-to-height ratio, and metabolic syndrome. | 2020 | Details |
| A08211 | 32202947 | Arch Physiol Biochem | All-Trans Retinoic Acid (atRA) effectively improves liver steatosis in a rabbit model of high fat induced liver steatosis. | 2020 | Details |
| A08212 | 32202088 | World J Mens Health | Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm. | 2020 | Details |
| A08215 | 32200254 | Biomed Pharmacother | Hepalatide ameliorated progression of nonalcoholic steatohepatitis in mice. | 2020 | Details |
| A08219 | 32196896 | Diabetes Obes Metab | Incretin combination therapy for the treatment of non-alcoholic steatohepatitis. | 2020 | Details |
| A08221 | 32195455 | JHEP Rep | Higher phenolic acid intake independently associates with lower prevalence of insulin resistance and non-alcoholic fatty liver disease. | 2020 | Details |
| A08231 | 32192216 | Int J Mol Sci | PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice. | 2020 | Details |
| A08233 | 32191646 | J Clin Invest | Influence of adiposity, insulin resistance, and intrahepatic triglyceride content on insulin kinetics. | 2020 | Details |
| A08234 | 32191577 | J Med Food | Eriocitrin Improves Adiposity and Related Metabolic Disorders in High-Fat Diet-Induced Obese Mice. | 2020 | Details |
| A08235 | 32191400 | Clin Pharmacol Drug Dev | Pharmacokinetics and Pharmacodynamics of Ursodeoxycholic Acid in an Overweight Population With Abnormal Liver Function. | 2020 | Details |
| A08236 | 32191345 | Hepatology | Hepatic Regulator of G Protein Signaling 5 Ameliorates Nonalcoholic Fatty Liver Disease by Suppressing Transforming Growth Factor Beta-Activated Kinase 1-c-Jun-N-Terminal Kinase/p38 Signaling. | 2020 | Details |
| A08243 | 32190149 | Arch Med Sci | Identification of key pathways and genes in nonalcoholic fatty liver disease using bioinformatics analysis. | 2020 | Details |
| A08248 | 32189102 | Dig Dis Sci | Progression to Cirrhosis Leads to Improvement in Atherogenic Milieu. | 2020 | Details |
| A08249 | 32188593 | BMJ Open Diabetes Res Care | Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism. | 2020 | Details |
| A08254 | 32187014 | J Pediatr Endocrinol Metab | Occurrence and clinical management of nonalcoholic fatty liver disease in obesity patients: a literature review. | 2020 | Details |
| A08259 | 32184641 | Diabetes Metab Syndr Obes | Relationship Between Helicobacter pylori Infection and Nonalcoholic Fatty Liver Disease (NAFLD) in a Developing Country: A Cross-Sectional Study. | 2020 | Details |
| A08260 | 32184638 | Diabetes Metab Syndr Obes | Lower Levels of Circulating Adiponectin in Elderly Patients with Metabolic Inflammatory Syndrome: A Cross-Sectional Study. | 2020 | Details |
| A08264 | 32181656 | J Agric Food Chem | Ginsenoside Rg2 Ameliorates High-Fat Diet-Induced Metabolic Disease through SIRT1. | 2020 | Details |
| A08268 | 32179679 | Proc Natl Acad Sci U S A | Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease. | 2020 | Details |
| A08273 | 32175323 | Front Med (Lausanne) | Hepatic Autonomic Nervous System and Neurotrophic Factors Regulate the Pathogenesis and Progression of Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A08276 | 32171530 | Biochem Biophys Res Commun | Liraglutide ameliorates obesity-related nonalcoholic fatty liver disease by regulating Sestrin2-mediated Nrf2/HO-1 pathway. | 2020 | Details |
| A08285 | 32169430 | Gastroenterology | Lactococcus lactis Subspecies cremoris Elicits Protection Against Metabolic Changes Induced by a Western-Style Diet. | 2020 | Details |
| A08287 | 32169080 | J Transl Med | Long noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway. | 2020 | Details |
| A08289 | 32168372 | Biochem J | Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics. | 2020 | Details |
| A08295 | 32165444 | Diabetes Care | Intrahepatic Fat and Postprandial Glycemia Increase After Consumption of a Diet Enriched in Saturated Fat Compared With Free Sugars. | 2020 | Details |
| A08296 | 32165250 | J Hepatol | Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping. | 2020 | Details |
| A08301 | 32161197 | JCI Insight | Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease. | 2020 | Details |
| A08308 | 32158249 | Clin Exp Gastroenterol | Effect of Ginger Powder Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2020 | Details |
| A08312 | 32156524 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease. | 2020 | Details |