Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19493 | 26524133 | Expert Rev Gastroenterol Hepatol | The role of chronic inflammation in the development of gastrointestinal cancers: reviewing cancer prevention with natural anti-inflammatory intervention. | 2015 | Details |
| A19500 | 26518991 | Transl Res | Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs. | 2015 | Details |
| A19502 | 26518313 | Lipids | Tyrosol Attenuates High Fat Diet-Induced Hepatic Oxidative Stress: Potential Involvement of Cystathionine β-Synthase and Cystathionine γ-Lyase. | 2015 | Details |
| A19536 | 26503843 | Liver Int | The effects of DASH diet on weight loss and metabolic status in adults with non-alcoholic fatty liver disease: a randomized clinical trial. | 2015 | Details |
| A19543 | 26498332 | Lipids Health Dis | Resveratrol ameliorates hepatic steatosis and inflammation in methionine/choline-deficient diet-induced steatohepatitis through regulating autophagy. | 2015 | Details |
| A19544 | 26498267 | Environ Toxicol Pharmacol | Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease. | 2015 | Details |
| A19550 | 26494227 | Carcinogenesis | Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats. | 2015 | Details |
| A19558 | 26486292 | Arq Gastroenterol | INFLUENCE OF OXIDATIVE STRESS AND OBESITY IN PATIENTS WITH NONALCOHOLIC STEATOHEPATITIS. | 2016 | Details |
| A19565 | 26482965 | Diabetes Metab Syndr | Gamma glutamyl transferase is an independent determinant for the association of insulin resistance with nonalcoholic fatty liver disease in Bangladeshi adults: Association of GGT and HOMA-IR with NAFLD. | 2015 | Details |
| A19573 | 28962484 | Toxicol Rep | Effects of 4-nonylphenol on oxidant/antioxidant balance system inducing hepatic steatosis in male rat. | 2015 | Details |
| A19576 | 26474534 | Biochim Biophys Acta | Purinergic receptor X7 mediates leptin induced GLUT4 function in stellate cells in nonalcoholic steatohepatitis. | 2015 | Details |
| A19579 | 26473919 | Nutrients | Optimized Rapeseed Oils Rich in Endogenous Micronutrients Protect High Fat Diet Fed Rats from Hepatic Lipid Accumulation and Oxidative Stress. | 2015 | Details |
| A19589 | 26471014 | Food Funct | Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet. | 2016 | Details |
| A19595 | 26464382 | J Mol Endocrinol | Glucose fluctuation increased hepatocyte apoptosis under lipotoxicity and the involvement of mitochondrial permeability transition opening. | 2015 | Details |
| A19596 | 26463841 | Lipids Health Dis | Investigation into the antioxidant role of arginine in the treatment and the protection for intralipid-induced non-alcoholic steatohepatitis. | 2015 | Details |
| A19598 | 26463593 | Genes Nutr | Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice. | 2015 | Details |
| A19601 | 26462866 | Diabetes Obes Metab | Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis. | 2015 | Details |
| A19603 | 26462272 | BMJ Open Gastroenterol | Systematic review of genetic association studies involving histologically confirmed non-alcoholic fatty liver disease. | 2015 | Details |
| A19604 | 26461414 | Free Radic Biol Med | Oxysterols in the orchestra of liver cell metabolism. | 2014 | Details |
| A19606 | 26461297 | Free Radic Biol Med | Oxysterols induce mitochondrial impairment and hepatocellular toxicity in non-alcoholic fatty liver disease. | 2014 | Details |
| A19607 | 26461295 | Free Radic Biol Med | The effect of Irisin on antioxidant system in liver. | 2014 | Details |
| A19632 | 26447219 | Am J Physiol Renal Physiol | NKT cell modulates NAFLD potentiation of metabolic oxidative stress-induced mesangial cell activation and proximal tubular toxicity. | 2015 | Details |
| A19635 | 26445592 | Nutr Metab (Lond) | Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1. | 2015 | Details |
| A19650 | 26436447 | Liver Int | Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives. | 2015 | Details |
| A19663 | 26428356 | Chem Biol Interact | Chemical characteristics for optimizing CYP2E1 inhibition. | 2015 | Details |
| A19685 | 26411937 | Nihon Eiseigaku Zasshi | [Mechanism Analysis and Prevention of Pathogenesis of Nonalcoholic Steatohepatitis]. | 2015 | Details |
| A19689 | 26408952 | Prostaglandins Other Lipid Mediat | Metabolites of arachidonic acid and linoleic acid in early stages of non-alcoholic fatty liver disease--A pilot study. | 2015 | Details |
| A19708 | 26401075 | World J Gastroenterol | Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. | 2015 | Details |
| A19709 | 26400185 | Am J Physiol Regul Integr Comp Physiol | Folic acid supplementation during high-fat diet feeding restores AMPK activation via an AMP-LKB1-dependent mechanism. | 2015 | Details |
| A19712 | 26399510 | Lipids | High Sucrose Intake Ameliorates the Accumulation of Hepatic Triacylglycerol Promoted by Restraint Stress in Young Rats. | 2015 | Details |
| A19717 | 26397061 | Mol Med Rep | Therapeutic effects of the dipeptidyl peptidase-IV inhibitor, sitagliptin, on non-alcoholic steatohepatitis in FLS-ob/ob male mice. | 2015 | Details |
| A19721 | 26395315 | Expert Rev Gastroenterol Hepatol | Cholesterol is a significant risk factor for non-alcoholic steatohepatitis. | 2015 | Details |
| A19729 | 26391864 | J Nutr Biochem | Dietary cholesterol induces hepatic inflammation and blunts mitochondrial function in the liver of high-fat-fed mice. | 2015 | Details |
| A19752 | 26378641 | Semin Liver Dis | Systemic Complications of Nonalcoholic Fatty Liver Disease: When the Liver Is Not an Innocent Bystander. | 2015 | Details |
| A19774 | 26358367 | Sci Rep | Hyperinsulinemia shifted energy supply from glucose to ketone bodies in early nonalcoholic steatohepatitis from high-fat high-sucrose diet induced Bama minipigs. | 2015 | Details |
| A19781 | 26355033 | Sci Transl Med | Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men. | 2015 | Details |
| A19787 | 26349165 | Trop Gastroenterol | Nonalcoholic Fatty Liver Disease--The Clinician's Perspective. | 2015 | Details |
| A19792 | 26347179 | Cell Biochem Funct | Changes in glucose transporter expression and nitric oxide production are associated with liver injury in diabetes. | 2015 | Details |
| A19810 | 26335400 | Redox Biol | Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences. | 2015 | Details |
| A19824 | 26325428 | Biochem Biophys Res Commun | Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity. | 2015 | Details |
| A19826 | 26323153 | Zhongguo Zhong Yao Za Zhi | [Experimental study on intervention effect of Grifola frondosa on nonalcoholic steatohepatitis]. | 2015 | Details |
| A19848 | 26310987 | Int J Cardiol | Mechanistic link between nonalcoholic fatty liver disease and cardiometabolic disorders. | 2015 | Details |
| A19859 | 26300958 | Chin Med | Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model. | 2015 | Details |
| A19878 | 26289505 | Niger J Clin Pract | Nonalcoholic fatty liver disease: Synopsis of current developments. | 2016 | Details |
| A19889 | 26282529 | Proc Nutr Soc | Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr-/- mice. | 2015 | Details |
| A19898 | 26278393 | Curr Mol Pharmacol | Role of CYP2E1 in Mitochondrial Dysfunction and Hepatic Injury by Alcohol and Non-Alcoholic Substances. | 2017 | Details |
| A19899 | 26278387 | Curr Mol Pharmacol | Review: Precision Cut Liver Slices for the Evaluation of Fatty Liver and Fibrosis. | 2017 | Details |
| A19907 | 26273604 | Biomed Res Int | The Potential Role of Iron and Copper in Pediatric Obesity and Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19925 | 26262841 | J Agric Food Chem | Mass-Spectrometry-Based Serum Metabolomics of a C57BL/6J Mouse Model of High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease Development. | 2015 | Details |
| A19970 | 26233911 | Adv Pharmacol | Translational Implications of the Alcohol-Metabolizing Enzymes, Including Cytochrome P450-2E1, in Alcoholic and Nonalcoholic Liver Disease. | 2015 | Details |
| A19988 | 26223319 | Free Radic Res | Endoplasmic reticulum stress and Oxidative stress in the pathogenesis of Non-alcoholic fatty liver disease. | 2015 | Details |
| A19993 | 26219393 | Curr Med Chem | The Pros and the Cons for the Use of Silybin-Rich Oral Formulations in Treatment of Liver Damage (NAFLD in Particular). | 2015 | Details |
| A19998 | 26215420 | Biomed Khim | [Intensity of apoptotic processes, aconitate hydratase activity and citrate level in patients with type 2 diabetes mellitus complicated steatohepatitis under application of epifamin at basic therapy]. | 2016 | Details |
| A20000 | 26215259 | Nat Rev Endocrinol | Physiological and pathophysiological roles of NAMPT and NAD metabolism. | 2015 | Details |
| A20002 | 26215060 | Turk J Gastroenterol | Increased plasma CgA levels associated with nonalcoholic fatty liver disease. | 2015 | Details |
| A20020 | 26202197 | Mini Rev Med Chem | Creatine and the Liver: Metabolism and Possible Interactions. | 2016 | Details |
| A20025 | 26201023 | Clin Sci (Lond) | Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis. | 2015 | Details |
| A20041 | 26194065 | Cytokine | PPARα/γ agonists and antagonists differently affect hepatic lipid metabolism, oxidative stress and inflammatory cytokine production in steatohepatitic rats. | 2015 | Details |
| A20054 | 26189985 | Clin Res Hepatol Gastroenterol | Synergy between NAFLD and AFLD and potential biomarkers. | 2015 | Details |
| A20078 | 26170532 | Mediators Inflamm | LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20088 | 26167244 | World J Hepatol | Is there a role for adaptive immunity in nonalcoholic steatohepatitis? | 2015 | Details |
| A20091 | 26160475 | Clin Res Hepatol Gastroenterol | Genetic polymorphisms and oxidative stress in non-alcoholic steatohepatitis (NASH): A mini review. | 2015 | Details |
| A20092 | 26160474 | Clin Res Hepatol Gastroenterol | Novel therapeutic targets for steatohepatitis. | 2015 | Details |
| A20105 | 26151688 | Acta Gastroenterol Belg | Serum levels of nitrate, nitrite and advanced oxidation protein products (AOPP) in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20107 | 26151056 | Hepatobiliary Surg Nutr | Carotenoids and non-alcoholic fatty liver disease. | 2015 | Details |
| A20116 | 26146507 | Evid Based Complement Alternat Med | Hugan Qingzhi Exerts Anti-Inflammatory Effects in a Rat Model of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20123 | 26140000 | World J Gastroenterol | Liver fat deposition and mitochondrial dysfunction in morbid obesity: An approach combining metabolomics with liver imaging and histology. | 2015 | Details |
| A20131 | 26137185 | Oxid Med Cell Longev | Choline and Cystine Deficient Diets in Animal Models with Hepatocellular Injury: Evaluation of Oxidative Stress and Expression of RAGE, TNF-α, and IL-1β. | 2015 | Details |
| A20134 | 26134756 | Pharm Biol | Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats. | 2015 | Details |
| A20138 | 26133299 | Eur J Nutr | Bee's honey attenuates non-alcoholic steatohepatitis-induced hepatic injury through the regulation of thioredoxin-interacting protein-NLRP3 inflammasome pathway. | 2015 | Details |
| A20157 | 26117210 | Vascul Pharmacol | Decreased plasma endogenous soluble RAGE, and enhanced adipokine secretion, oxidative stress and platelet/coagulative activation identify non-alcoholic fatty liver disease among patients with familial combined hyperlipidemia and/or metabolic syndrome. | 2015 | Details |
| A20186 | 26098879 | PLoS One | Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet. | 2015 | Details |
| A20192 | 26090514 | ScientificWorldJournal | Histologic and Metabolic Derangement in High-Fat, High-Fructose, and Combination Diet Animal Models. | 2015 | Details |
| A20205 | 26085904 | World J Hepatol | Understanding the pathophysiological mechanisms in the pediatric non-alcoholic fatty liver disease: The role of genetics. | 2015 | Details |
| A20218 | 26078820 | Oxid Med Cell Longev | Rimonabant Improves Oxidative/Nitrosative Stress in Mice with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20243 | 26066519 | Toxicology | A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells. | 2015 | Details |
| A20246 | 26064858 | J Lifestyle Med | SIRT3 as a Regulator of Non-alcoholic Fatty Liver Disease. | 2014 | Details |
| A20257 | 26060181 | J Bioenerg Biomembr | Protective effects of dietary avocado oil on impaired electron transport chain function and exacerbated oxidative stress in liver mitochondria from diabetic rats. | 2015 | Details |
| A20260 | 26058518 | Antioxid Redox Signal | Myeloperoxidase-Hepatocyte-Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20271 | 26052378 | World J Hepatol | Oxidative stress: New insights on the association of non-alcoholic fatty liver disease and atherosclerosis. | 2015 | Details |
| A20272 | 26052375 | World J Hepatol | Pathophysiological mechanisms involved in non-alcoholic steatohepatitis and novel potential therapeutic targets. | 2015 | Details |
| A20286 | 26045616 | Am J Physiol Gastrointest Liver Physiol | Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation. | 2015 | Details |
| A20305 | 26038701 | Pharmacol Res Perspect | Metformin protects primary rat hepatocytes against oxidative stress-induced apoptosis. | 2015 | Details |
| A20324 | 26028044 | Curr Drug Targets | Natural Products on Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20336 | 26024755 | Metabolism | Niacin inhibits fat accumulation, oxidative stress, and inflammatory cytokine IL-8 in cultured hepatocytes: Impact on non-alcoholic fatty liver disease. | 2015 | Details |
| A20342 | 26020857 | Nanomedicine (Lond) | Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis. | 2015 | Details |
| A20356 | 26018346 | Mol Med Rep | Intrahepatic transplantation of adipose-derived stem cells attenuates the progression of non-alcoholic fatty liver disease in rats. | 2015 | Details |
| A20358 | 26017539 | PLoS One | Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease. | 2015 | Details |
| A20361 | 26017323 | Int J Food Sci Nutr | Effects of eicosapentaenoic acid on hepatic dyslipidemia and oxidative stress in high fat diet-induced steatosis. | 2015 | Details |
| A20365 | 26013469 | J Nutr Biochem | Platelet-activating factor modulates fat storage in the liver induced by a high-refined carbohydrate-containing diet. | 2015 | Details |
| A20383 | 26000287 | Biomed Res Int | Inhibitory effects of eucalyptus and banaba leaf extracts on nonalcoholic steatohepatitis induced by a high-fructose/high-glucose diet in rats. | 2015 | Details |
| A20385 | 25999428 | Am J Physiol Gastrointest Liver Physiol | The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model. | 2015 | Details |
| A20397 | 25993337 | PLoS One | Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. | 2015 | Details |
| A20407 | 25987847 | Nutr Metab Insights | Choline and Fructooligosaccharide: Non-alcoholic Fatty Liver Disease, Cardiac Fat Deposition, and Oxidative Stress Markers. | 2015 | Details |
| A20426 | 25974206 | Sci Rep | Chronic inflammation aggravates metabolic disorders of hepatic fatty acids in high-fat diet-induced obese mice. | 2015 | Details |
| A20436 | 25967348 | Eur J Pharmacol | Epigallocatechin gallate attenuated non-alcoholic steatohepatitis induced by methionine- and choline-deficient diet. | 2015 | Details |
| A20451 | 25955209 | Cell Metab | Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. | 2015 | Details |
| A20452 | 25954315 | Evid Based Complement Alternat Med | Vitex agnus-castus L. (Verbenaceae) Improves the Liver Lipid Metabolism and Redox State of Ovariectomized Rats. | 2015 | Details |
| A20460 | 25947915 | Biol Pharm Bull | The Glucagon-Like Peptide-1 Analogue Liraglutide Inhibits Oxidative Stress and Inflammatory Response in the Liver of Rats with Diet-Induced Non-alcoholic Fatty Liver Disease. | 2015 | Details |
| A20483 | 25934114 | Nutr Res | Lowering the dietary omega-6: omega-3 does not hinder nonalcoholic fatty-liver disease development in a murine model. | 2015 | Details |