Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
lipogenesis1889 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52053 | 31879395 | Gan To Kagaku Ryoho | [Basic Science of Cancer Cachexia]. | 2019 | Details |
| A52055 | 31852997 | Int J Obes (Lond) | Gestational diabetes and maternal obesity are associated with sex-specific changes in miRNA and target gene expression in the fetus. | 2019 | Details |
| A52071 | 31676441 | Biochim Biophys Acta Mol Cell Biol Lipids | PPARA/RXRA signalling regulates the fate of hepatic non-esterified fatty acids in a sheep model of maternal undernutrition. | 2019 | Details |
| A52079 | 31577934 | Cell Metab | Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. | 2019 | Details |
| A52080 | 31573846 | Am J Physiol Endocrinol Metab | The antagonist of CXCR1 and CXCR2 protects db/db mice from metabolic diseases through modulating inflammation. | 2019 | Details |
| A52091 | 31357412 | Int J Mol Sci | Adipogenesis: A Necessary but Harmful Strategy. | 2019 | Details |
| A52092 | 31340878 | Proc Nutr Soc | Different physiological mechanisms underlie an adverse cardiovascular disease risk profile in men and women. | 2019 | Details |
| A52096 | 31307210 | FASEB J | Ileal interposition surgery targets the hepatic TGF-β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD-T2DM rat model of diabetes. | 2019 | Details |
| A52101 | 31243135 | J Virol | Transforming Growth Factor β Acts as a Regulatory Molecule for Lipogenic Pathways among Hepatitis C Virus Genotype-Specific Infections. | 2019 | Details |
| A52114 | 31053639 | J Biol Chem | An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice. | 2019 | Details |
| A52128 | 30936147 | Diabetes | Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls. | 2019 | Details |
| A52130 | 30921498 | Mol Nutr Food Res | Dietary Palmitoleic Acid Attenuates Atherosclerosis Progression and Hyperlipidemia in Low-Density Lipoprotein Receptor-Deficient Mice. | 2019 | Details |
| A52161 | 30559212 | Proc Natl Acad Sci U S A | AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis. | 2018 | Details |
| A52171 | 30463291 | Nutrients | Ishige okamurae Extract Suppresses Obesity and Hepatic Steatosis in High Fat Diet-Induced Obese Mice. | 2018 | Details |
| A52173 | 30425250 | Nat Commun | Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN. | 2018 | Details |
| A52193 | 30246717 | Chin Med J (Engl) | Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 Cells. | 2018 | Details |
| A52196 | 30212233 | Chronobiol Int | Timing of food intake is more potent than habitual voluntary exercise to prevent diet-induced obesity in mice. | 2018 | Details |
| A52198 | 30201971 | Nat Commun | ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes. | 2018 | Details |
| A52204 | 30133327 | FASEB J | Chronic psychosocial defeat differently affects lipid metabolism in liver and white adipose tissue and induces hepatic oxidative stress in mice fed a high-fat diet. | 2018 | Details |
| A52206 | 30131158 | Food Res Int | Extruded sorghum (Sorghum bicolor L.) reduces metabolic risk of hepatic steatosis in obese rats consuming a high fat diet. | 2018 | Details |
| A52208 | 30109419 | Eur J Nutr | Metabolic alterations associated with maternal undernutrition during the first half of gestation lead to a diabetogenic state in the rat. | 2018 | Details |
| A52212 | 30060615 | Mar Drugs | Functional Comparison of High and Low Molecular Weight Chitosan on Lipid Metabolism and Signals in High-Fat Diet-Fed Rats. | 2018 | Details |
| A52213 | 30049588 | Nutr Res | The interplay of canonical and noncanonical Wnt signaling in metabolic syndrome. | 2018 | Details |
| A52231 | 29897997 | PLoS One | The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life. | 2018 | Details |
| A52237 | 29872321 | Onco Targets Ther | Downregulation of CPT2 promotes tumorigenesis and chemoresistance to cisplatin in hepatocellular carcinoma. | 2018 | Details |
| A52244 | 29751049 | Toxicol Appl Pharmacol | Increased butyrate priming in the gut stalls microbiome associated-gastrointestinal inflammation and hepatic metabolic reprogramming in a mouse model of Gulf War Illness. | 2018 | Details |
| A52247 | 29705001 | Biomaterials | Dendritic peptide bolaamphiphiles for siRNA delivery to primary adipocytes. | 2018 | Details |
| A52252 | 29681858 | Front Pharmacol | Aqueous Extract of Black Maca Prevents Metabolism Disorder via Regulating the Glycolysis/Gluconeogenesis-TCA Cycle and PPARα Signaling Activation in Golden Hamsters Fed a High-Fat, High-Fructose Diet. | 2018 | Details |
| A52259 | 29596053 | Horm Mol Biol Clin Investig | The "adipose tissue expandability" hypothesis: a potential mechanism for insulin resistance in obese youth. | 2018 | Details |
| A52275 | 29402742 | Bioorg Med Chem Lett | Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice. | 2018 | Details |
| A52286 | 29173222 | Br J Nutr | Maternal conjugated linoleic acid modulates TAG metabolism in adult rat offspring. | 2017 | Details |
| A52289 | 29074588 | Arterioscler Thromb Vasc Biol | GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. | 2017 | Details |
| A52290 | 29074585 | Arterioscler Thromb Vasc Biol | Δ-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators. | 2017 | Details |
| A52315 | 28759094 | J Am Osteopath Assoc | Conversion of Sugar to Fat: Is Hepatic de Novo Lipogenesis Leading to Metabolic Syndrome and Associated Chronic Diseases? | 2017 | Details |
| A52327 | 28545035 | Oncotarget | Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. | 2017 | Details |
| A52334 | 28431322 | J Nutr Biochem | Xanthohumol and 8-prenylnaringenin ameliorate diabetic-related metabolic dysfunctions in mice. | 2017 | Details |
| A52345 | 28375880 | Curr Opin Clin Nutr Metab Care | AMP-activated protein kinase, fatty acid metabolism, and insulin sensitivity. | 2017 | Details |
| A52367 | 28110829 | Prostaglandins Leukot Essent Fatty Acids | Lipidomic analysis reveals significant lipogenesis and accumulation of lipotoxic components in ob/ob mouse organs. | 2017 | Details |
| A52368 | 28100772 | J Biol Chem | De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis. | 2017 | Details |
| A52387 | 27799461 | J Endocrinol | Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice. | 2016 | Details |
| A52430 | 27203212 | Oncotarget | Organochloride pesticides induced hepatic ABCG5/G8 expression and lipogenesis in Chinese patients with gallstone disease. | 2016 | Details |
| A52453 | 26980761 | Cancer Res | Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade. | 2016 | Details |
| A52476 | 26562264 | Endocrinology | Androgen Deficiency Exacerbates High-Fat Diet-Induced Metabolic Alterations in Male Mice. | 2015 | Details |
| A52480 | 26491440 | Int J Endocrinol | Sex Hormones and Their Receptors Regulate Liver Energy Homeostasis. | 2015 | Details |
| A52494 | 26382148 | J Vis Exp | Determination of Fatty Acid Oxidation and Lipogenesis in Mouse Primary Hepatocytes. | 2015 | Details |
| A52527 | 25984792 | PLoS One | Associations of Erythrocyte Fatty Acids in the De Novo Lipogenesis Pathway with Proxies of Liver Fat Accumulation in the EPIC-Potsdam Study. | 2015 | Details |
| A52529 | 25943649 | Eur J Nutr | Fasting for 3 days during the suckling-weaning transient period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood. | 2015 | Details |
| A52538 | 25854303 | Endocrine | Short-term administration of GW501516 improves inflammatory state in white adipose tissue and liver damage in high-fructose-fed mice through modulation of the renin-angiotensin system. | 2015 | Details |
| A52564 | 25582085 | Nutr Res | Early hepatic insult in the offspring of obese maternal mice. | 2014 | Details |
| A52570 | 25487878 | Sci Rep | Protopanaxatriol, a novel PPARγ antagonist from Panax ginseng, alleviates steatosis in mice. | 2014 | Details |
| A52592 | 25220251 | J Hepatol | Hepatitis C viral proteins perturb metabolic liver zonation. | 2014 | Details |
| A52628 | 24605027 | World J Gastroenterol | Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer. | 2014 | Details |
| A52631 | 24486395 | Eur J Pharmacol | Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat. | 2014 | Details |
| A52650 | 24184811 | Gastroenterology | Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21. | 2013 | Details |
| A52656 | 24069385 | PLoS One | SCD1 Expression is dispensable for hepatocarcinogenesis induced by AKT and Ras oncogenes in mice. | 2013 | Details |
| A52667 | 23926602 | J Clin Invest | Prenatal sensitization of a postnatal trigger for metabolic disease. | 2013 | Details |
| A52675 | 23746045 | J Proteome Res | High-fat diet induces dynamic metabolic alterations in multiple biological matrices of rats. | 2013 | Details |
| A52683 | 23565157 | PLoS One | A metabolomic analysis of two intravenous lipid emulsions in a murine model. | 2013 | Details |
| A52685 | 23551521 | J Intern Med | Ectopic lipid storage and insulin resistance: a harmful relationship. | 2013 | Details |
| A52691 | 23476706 | Evid Based Complement Alternat Med | Freshwater Clam Extract Ameliorates Triglyceride and Cholesterol Metabolism through the Expression of Genes Involved in Hepatic Lipogenesis and Cholesterol Degradation in Rats. | 2013 | Details |
| A52694 | 23431266 | PLoS Biol | Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. | 2013 | Details |
| A52714 | 23043895 | Trends Endocrinol Metab | Dissociating fatty liver and diabetes. | 2012 | Details |
| A52740 | 22547685 | Mol Cell Biol | BNip3 regulates mitochondrial function and lipid metabolism in the liver. | 2012 | Details |
| A52742 | 22546076 | Atherosclerosis | Multiple factors and pathways involved in hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima Fatty rats. | 2012 | Details |
| A52760 | 22351884 | Pediatrics | Toward a unifying hypothesis of metabolic syndrome. | 2012 | Details |
| A52783 | 22005032 | Biochim Biophys Acta | Hypertriglyceridemia secondary to obesity and diabetes. | 2011 | Details |
| A52812 | 21453770 | Biochim Biophys Acta | Cross-regulation of hepatic glucose metabolism via ChREBP and nuclear receptors. | 2011 | Details |
| A52818 | 21336545 | Naunyn Schmiedebergs Arch Pharmacol | Overweight induced by chronic risperidone exposure is correlated with overexpression of the SREBP-1c and FAS genes in mouse liver. | 2011 | Details |
| A52832 | 21151924 | PLoS One | Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice. | 2010 | Details |
| A52850 | 20699090 | Clin Chim Acta | Triglycerides and gallstone formation. | 2010 | Details |
| A52866 | 20487553 | BMC Gastroenterol | Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosis. | 2010 | Details |
| A52877 | 20332082 | Mol Cell Proteomics | Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet. | 2010 | Details |
| A52889 | 19937189 | J Gastrointest Surg | Does LKB1 mediate activation of hepatic AMP-protein kinase (AMPK) and sirtuin1 (SIRT1) after Roux-en-Y gastric bypass in obese rats? | 2010 | Details |
| A52894 | 19854061 | Trends Endocrinol Metab | Hepatitis C virus hijacks host lipid metabolism. | 2009 | Details |
| A52900 | 19808675 | J Biol Chem | Hepatitis C virus proteins induce lipogenesis and defective triglyceride secretion in transgenic mice. | 2009 | Details |
| A52922 | 19501581 | Clin Biochem | Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. | 2009 | Details |
| A52923 | 19500808 | Metabolism | A herbal extract with acetyl-coenzyme A carboxylase inhibitory activity and its potential for treating metabolic syndrome. | 2009 | Details |
| A52943 | 19201949 | Development | TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase. | 2009 | Details |
| A52955 | 18930334 | J Hepatol | Dietary resveratrol alters lipid metabolism-related gene expression of mice on an atherogenic diet. | 2008 | Details |
| A52965 | 18691015 | Curr Drug Targets | Group VI phospholipases A2: homeostatic phospholipases with significant potential as targets for novel therapeutics. | 2008 | Details |
| A52978 | 18446001 | Endocr J | Molecular mechanism of moderate insulin resistance in adiponectin-knockout mice. | 2008 | Details |
| A53002 | 17925761 | Gastroenterol Clin Biol | [Steatosis during chronic hepatitis C: the role of insulin resistance and viral factors]. | 2008 | Details |
| A53014 | 17466100 | Proc Nutr Soc | The interplay between nutrients and the adipose tissue. | 2007 | Details |
| A53050 | 16477380 | Mol Cell Biochem | Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. | 2006 | Details |
| A53075 | 15589689 | Biochimie | Effects of streptozotocin and dietary fructose on delta-6 desaturation in spontaneously hypertensive rat liver. | 2004 | Details |
| A53119 | 12373575 | Eur J Pediatr | Disturbed lipid metabolism in glycogen storage disease type 1. | 2002 | Details |
| A53129 | 11712670 | Life Sci | Can associations between free fatty acid levels and metabolic parameters determine insulin resistance development in obese Zucker rats? | 2001 | Details |
| A53130 | 11679439 | Diabetes | Acute inhibition of glucose-6-phosphate translocator activity leads to increased de novo lipogenesis and development of hepatic steatosis without affecting VLDL production in rats. | 2001 | Details |
| A53190 | 857644 | Am J Clin Nutr | Metabolic regulation as a control for lipid disorders. II. Influence of (--)-hydroxycitrate on genetically and experimentally induced hypertriglyceridemia in the rat. | 1977 | Details |