Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00958 | 34919135 | JAMA Netw Open | Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials. | 2021 | Details |
| A00965 | 34917315 | Frontline Gastroenterol | Implementation of a care bundle improves the management of patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A00974 | 34914849 | J Intern Med | Liver damage promotes pro-inflammatory T-cell responses against apolipoprotein B-100. | 2022 | Details |
| A00979 | 34911587 | BMC Nutr | Effect of omega-3 supplementation on cardiometabolic indices in diabetic patients with non-alcoholic fatty liver disease: a randomized controlled trial. | 2021 | Details |
| A00984 | 34909896 | Rev Assoc Med Bras (1992) | Nonalcoholic fatty liver disease: scintigraphy in the diagnosis of steatohepatitis. | 2021 | Details |
| A00987 | 34909677 | Curr Res Pharmacol Drug Discov | ATP citrate lyase inhibitor Bempedoic Acid alleviate long term HFD induced NASH through improvement in glycemic control, reduction of hepatic triglycerides & total cholesterol, modulation of inflammatory & fibrotic genes and improvement in NAS score. | 2021 | Details |
| A01020 | 34901236 | Front Cardiovasc Med | Statins in Non-alcoholic Steatohepatitis. | 2021 | Details |
| A01055 | 34886772 | Curr Alzheimer Res | Metabolic Syndrome, Alzheimer's Disease, and Covid 19: A Possible Correlation. | 2021 | Details |
| A01097 | 34870138 | Metabol Open | Metabolic causes and consequences of nonalcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A01107 | 34867384 | Front Pharmacol | Effects of Nigella sativa, Camellia sinensis, and Allium sativum as Food Additives on Metabolic Disorders, a Literature Review. | 2021 | Details |
| A01117 | 34864598 | Int J Hyg Environ Health | Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds is associated with a risk of obesity and diabetes mellitus among Korean adults: Korean National Environmental Health Survey (KoNEHS) 2015-2017. | 2021 | Details |
| A01124 | 34862975 | FASEB J | Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling. | 2022 | Details |
| A01131 | 34860705 | Eur J Gastroenterol Hepatol | Effects of naringenin supplementation on cardiovascular risk factors in overweight/obese patients with nonalcoholic fatty liver disease: a pilot double-blind, placebo-controlled, randomized clinical trial. | 2022 | Details |
| A01133 | 34860208 | J Occup Environ Med | Determination of Cardiovascular Risk in 56,262 Spanish Construction Workers: Cardiovascular Risk in Construction Workers. | 2021 | Details |
| A01139 | 34857248 | Clin Nutr ESPEN | Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial. | 2021 | Details |
| A01147 | 34855339 | FP Essent | Liver Disease: Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01151 | 34853949 | Handb Exp Pharmacol | Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance. | 2021 | Details |
| A01153 | 34851748 | Can J Physiol Pharmacol | The anti-anginal ranolazine does not confer beneficial actions against hepatic steatosis in male mice subjected to high-fat diet and streptozotocin-induced type 2 diabetes. | 2021 | Details |
| A01155 | 34850615 | Clin Chem Lab Med | Afamin predicts the prevalence and incidence of nonalcoholic fatty liver disease. | 2021 | Details |
| A01174 | 34840719 | Ther Adv Endocrinol Metab | NAFLD in type 1 diabetes: overrated or underappreciated? | 2021 | Details |
| A01192 | 34833467 | Medicina (Kaunas) | Correlations between PNPLA3 Gene Polymorphisms and NAFLD in Type 2 Diabetic Patients. | 2021 | Details |
| A01202 | 34829926 | Biomedicines | Non-Alcoholic Fatty Liver Disease (NAFLD) and Potential Links to Depression, Anxiety, and Chronic Stress. | 2021 | Details |
| A01209 | 34829402 | Diagnostics (Basel) | Involvement of Ceramides in Non-Alcoholic Fatty Liver Disease (NAFLD) Atherosclerosis (ATS) Development: Mechanisms and Therapeutic Targets. | 2021 | Details |
| A01210 | 34829394 | Diagnostics (Basel) | A Step Closer to the "Fourth 90": A Practical Narrative Review of Diagnosis and Management of Nutritional Issues of People Living with HIV. | 2021 | Details |
| A01215 | 34827579 | Biomolecules | Effect of Bariatric Surgery on Metabolic Diseases and Underlying Mechanisms. | 2021 | Details |
| A01237 | 34818080 | Metab Syndr Relat Disord | Increased Serum Pentraxin 3 Is Associated with Prediabetes and Type 2 Diabetes in Obese Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01246 | 34815180 | Trends Mol Med | Linking liver metabolic and vascular disease via bile acid signaling. | 2021 | Details |
| A01265 | 34808701 | Phytother Res | Esculetin: A review of its pharmacology and pharmacokinetics. | 2021 | Details |
| A01274 | 34805582 | Transl Gastroenterol Hepatol | Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis. | 2021 | Details |
| A01292 | 34799510 | Curr Opin Infect Dis | Frailty in people living with HIV: an update. | 2022 | Details |
| A01295 | 34798835 | BMC Gastroenterol | PNPLA3 genotype and fibrosis-4 index predict cardiovascular diseases of Japanese patients with histopathologically-confirmed NAFLD. | 2021 | Details |
| A01298 | 34798124 | Biochem Pharmacol | CYP4V2 fatty acid omega hydroxylase, a druggable target for the treatment of metabolic associated fatty liver disease (MAFLD). | 2021 | Details |
| A01299 | 34797530 | Rheumatol Ther | Psoriatic Arthritis: The Influence of Co-morbidities on Drug Choice. | 2021 | Details |
| A01318 | 34789138 | Curr Med Imaging | Evaluation of Aortic Distensibility in Patients with Nonalcoholic Fatty Liver using CT. | 2021 | Details |
| A01344 | 34780785 | Exp Cell Res | MicroRNA-22 inhibition promotes the development of atherosclerosis via targeting interferon regulator factor 5. | 2021 | Details |
| A01348 | 34779464 | Food Funct | MUFA in metabolic syndrome and associated risk factors: is MUFA the opposite side of the PUFA coin? | 2021 | Details |
| A01357 | 34776827 | Food Nutr Res | Weissella cibaria MG5285 and Lactobacillus reuteri MG5149 attenuated fat accumulation in adipose and hepatic steatosis in high-fat diet-induced C57BL/6J obese mice. | 2021 | Details |
| A01374 | 34769488 | Int J Mol Sci | The Roles of Carbohydrate Response Element Binding Protein in the Relationship between Carbohydrate Intake and Diseases. | 2021 | Details |
| A01377 | 34769060 | Int J Mol Sci | Pathophysiological Molecular Mechanisms of Obesity: A Link between MAFLD and NASH with Cardiovascular Diseases. | 2021 | Details |
| A01381 | 34768440 | J Clin Med | Prothrombotic and Inflammatory Markers in Elderly Patients with Non-Alcoholic Hepatic Liver Disease before and after Weight Loss: A Pilot Study. | 2021 | Details |
| A01384 | 34765249 | Curr Health Sci J | Contribution of Modern Echocardiographic Techniques in the Detection of Subclinical Heart Dysfunction in Young Adults with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01395 | 34762106 | JAMA | Association of Bariatric Surgery With Major Adverse Liver and Cardiovascular Outcomes in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis. | 2021 | Details |
| A01400 | 34759828 | Front Pharmacol | Hepatopathy Associated With Type 1 Diabetes: Distinguishing Non-alcoholic Fatty Liver Disease From Glycogenic Hepatopathy. | 2021 | Details |
| A01430 | 34749893 | Nurs Clin North Am | Obesity and Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01463 | 34738990 | J Hypertens | Fatty liver index and hypertension-mediated organ damage in never-treated hypertensive patients without diabetes mellitus. | 2021 | Details |
| A01466 | 34737121 | J Mol Cell Cardiol | NAFLD as a continuous driver in the whole spectrum of vascular disease. | 2021 | Details |
| A01470 | 34736334 | Ceska Gynekol | Conservative possibilities influencing PCOS syndrome - the importance of nutrition. | 2021 | Details |
| A01472 | 34734674 | Pediatr Obes | Exercise dose on hepatic fat and cardiovascular health in adolescents with excess of adiposity. | 2021 | Details |
| A01491 | 34726318 | Diabetes Obes Metab | Young adults with nonalcoholic fatty liver disease, defined using the fatty liver index, can be at increased risk of myocardial infarction or stroke. | 2021 | Details |
| A01504 | 34719614 | J Nutr Sci Vitaminol (Tokyo) | Effect of Hyperbaric Oxygen Therapy (HBOT) on Insulin Resistance Associated with Abdominal Obesity in Wistar Rats with Dietary Sucrose-Induced Metabolic Syndrome. | 2021 | Details |
| A01505 | 34718898 | Egypt Heart J | The associations between coronary artery disease, and non-alcoholic fatty liver disease by computed tomography. | 2021 | Details |
| A01510 | 34716911 | Hormones (Athens) | Association of cardiovascular factors in diabetic patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A01511 | 34715296 | Free Radic Biol Med | Role of vitamin E in the treatment of non-alcoholic steatohepatitis. | 2021 | Details |
| A01515 | 34712447 | Middle East J Dig Dis | Evaluating Pancreatic index in Patients with and without Metabolic Syndrome. | 2021 | Details |
| A01533 | 34707201 | Sci Rep | Characterization of a murine model of endothelial dysfunction induced by chronic intraperitoneal administration of angiotensin II. | 2021 | Details |
| A01540 | 34704339 | Trop Med Int Health | Hepatic steatosis is associated with anthropometry, cardio-metabolic disease risk, sex, age and urbanisation, but not with ethnicity in adult Kenyans. | 2021 | Details |
| A01545 | 34702329 | Diabetol Metab Syndr | Association of anti-oxidative capacity of HDL with subclinical atherosclerosis in subjects with and without non-alcoholic fatty liver disease. | 2021 | Details |
| A01550 | 34697666 | Handb Exp Pharmacol | Obesity and Obstructive Sleep Apnea. | 2021 | Details |
| A01562 | 34693236 | JHEP Rep | Non-alcoholic fatty liver disease: A patient guideline. | 2021 | Details |
| A01563 | 34692739 | Front Med (Lausanne) | Hypoxia-Inducible Factors as Key Players in the Pathogenesis of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis. | 2021 | Details |
| A01575 | 34688168 | Curr Opin Pharmacol | Non-alcoholic fatty liver disease: Current therapeutic options. | 2021 | Details |
| A01580 | 34686147 | BMC Gastroenterol | The liver steatosis severity and lipid characteristics in primary biliary cholangitis. | 2021 | Details |
| A01584 | 34684698 | Molecules | Natural Aporphine Alkaloids with Potential to Impact Metabolic Syndrome. | 2021 | Details |
| A01594 | 34684335 | Nutrients | Pathway Preferential Estrogens Prevent Hepatosteatosis Due to Ovariectomy and High-Fat Diets. | 2021 | Details |
| A01595 | 34684094 | Medicina (Kaunas) | Non-Alcoholic Fatty Liver Disease and COVID-19-Two Pandemics Hitting at the Same Time. | 2021 | Details |
| A01611 | 34680486 | Biomedicines | Nonalcoholic Fatty Liver Disease and the Kidney: A Review. | 2021 | Details |
| A01613 | 34680463 | Biomedicines | Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges. | 2021 | Details |
| A01623 | 34678296 | Clin Chim Acta | The potential pathophysiological role of altered lipid metabolism and electronegative low-density lipoprotein (LDL) in non-alcoholic fatty liver disease and cardiovascular diseases. | 2021 | Details |
| A01627 | 34677008 | Hepatol Commun | Low Lipoprotein(a) Levels Predict Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01690 | 34653272 | Aliment Pharmacol Ther | Trends in statin utilisation in US adults with non-alcoholic fatty liver disease. | 2021 | Details |
| A01729 | 34635626 | Gut Liver | Metabolic Dysfunction-Associated Fatty Liver Disease Predicts Long-term Mortality and Cardiovascular Disease. | 2022 | Details |
| A01745 | 34630157 | Front Physiol | Effect of Exercise Training on Fat Loss-Energetic Perspectives and the Role of Improved Adipose Tissue Function and Body Fat Distribution. | 2021 | Details |
| A01747 | 34629804 | World J Gastroenterol | Screening for nonalcoholic fatty liver disease-when, who and how? | 2021 | Details |
| A01748 | 34629802 | World J Gastroenterol | Relationship between nonalcoholic fatty liver disease and chronic kidney disease could start in childhood. | 2021 | Details |
| A01750 | 34629256 | Nutr Metab Cardiovasc Dis | Extent and features of liver steatosis in vitro pave the way to endothelial dysfunction without physical cell-to-cell contact. | 2021 | Details |
| A01756 | 34628383 | Georgian Med News | THE INFLUENCE OF HYPERCHOLESTEROLEMIA AND CONCOMITANT STATIN THERAPY ON THE STATE OF PLATELET-PLASMA HEMOSTASIS IN PATIENTS WITH ESSENTIAL HYPERTENSION AND NON-ALCOHOLIC FATTY LIVER DISEASE. | 2021 | Details |
| A01757 | 34628102 | Atherosclerosis | IDO activity forecasts obesity in males and premenopausal females in a 10-year follow-up study:The Cardiovascular Risk in Young Finns Study. | 2021 | Details |
| A01760 | 34627696 | Nutr Metab Cardiovasc Dis | Association between non-alcoholic fatty liver disease and impaired cardiac sympathetic/parasympathetic balance in subjects with and without type 2 diabetes-The Cooperative Health Research in South Tyrol (CHRIS)-NAFLD sub-study. | 2021 | Details |
| A01761 | 34627692 | Nutr Metab Cardiovasc Dis | Beneficial effects of glucagon-like peptide 1 receptor agonists on glucose control, cardiovascular risk profile, and non-alcoholic fatty liver disease. An expert opinion of the Italian diabetes society. | 2021 | Details |
| A01762 | 34626855 | Mol Metab | The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis. | 2021 | Details |
| A01766 | 34626331 | Hepatol Int | Metabolic-associated fatty liver disease and major adverse cardiac events in patients with chronic coronary syndrome: a matched case-control study. | 2021 | Details |
| A01785 | 34618982 | FASEB J | Omega-3 carboxylic acids and fenofibrate differentially alter plasma lipid mediators in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A01829 | 34602251 | Gastroenterology | Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01831 | 34601620 | J Gastroenterol | Risk of cardiovascular disease in patients with fatty liver disease as defined from the metabolic dysfunction associated fatty liver disease or nonalcoholic fatty liver disease point of view: a retrospective nationwide claims database study in Japan. | 2021 | Details |
| A01836 | 34600906 | Metabolism | The presence of NAFLD influences the transition of metabolically healthy to metabolically unhealthy obesity and the ten-year cardiovascular disease risk: A population-based cohort study. | 2021 | Details |
| A01850 | 34590082 | Aust J Gen Pract | Updates in fatty liver disease: Pathophysiology, diagnosis and management. | 2021 | Details |
| A01851 | 34589520 | Front Mol Biosci | Saliva and Plasma Reflect Metabolism Altered by Diabetes and Periodontitis. | 2021 | Details |
| A01860 | 34585892 | J Assoc Physicians India | Management of Hyperglycemia in COVID-19 and Post-COVID-19 Syndrome - Proposed Guidelines for India. | 2021 | Details |
| A01863 | 34584580 | Prz Gastroenterol | Association of non-alcoholic fatty liver disease with coronary artery calcification progression: a systematic review and meta-analysis. | 2021 | Details |
| A01864 | 34583706 | Cardiovasc Diabetol | The association of hepatic steatosis and fibrosis with heart failure and mortality. | 2021 | Details |
| A01904 | 34565785 | Korean J Gastroenterol | Early Cardiac Dysfunction in Biopsy-proven Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01909 | 34565074 | Rev Cardiovasc Med | Pathophysiological mechanisms and clinical evidence of relationship between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease. | 2021 | Details |
| A01922 | 34560854 | Cardiovasc Diabetol | Prognostic impact of liver fibrosis and steatosis by transient elastography for cardiovascular and mortality outcomes in individuals with nonalcoholic fatty liver disease and type 2 diabetes: the Rio de Janeiro Cohort Study. | 2021 | Details |
| A01926 | 34560278 | Clin Gastroenterol Hepatol | A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary Heart Disease in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01930 | 34558862 | Hepatol Commun | Risk of Cardiovascular Disease in Individuals With Nonobese Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01931 | 34558856 | Hepatol Commun | Role of Cholesterol-Associated Steatohepatitis in the Development of NASH. | 2021 | Details |
| A01945 | 34557498 | Front Med (Lausanne) | Fecal Microbiota Transplantation as a Tool for Therapeutic Modulation of Non-gastrointestinal Disorders. | 2021 | Details |
| A01949 | 34557366 | Cureus | The Troubling Link Between Non-alcoholic Fatty Liver Disease (NAFLD) and Extrahepatic Cancers (EHC). | 2021 | Details |
| A01953 | 34555346 | Lancet Gastroenterol Hepatol | Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis. | 2021 | Details |
| A01959 | 34552789 | Arab J Urol | Testosterone treatment improves liver function and reduces cardiovascular risk: A long-term prospective study. | 2021 | Details |