Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Caspase-1136 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A29903 | 33296631 | Med Sci (Paris) | [Caspase inhibition: From cellular biology and thanatology to potential clinical agents]. | 2020 | Details |
| A30670 | 32021639 | Nutr Metab (Lond) | Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis. | 2020 | Details |
| A30905 | 31585800 | Mol Ther | MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury. | 2019 | Details |
| A31661 | 30084831 | J Lipid Res | Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice. | 2018 | Details |
| A32305 | 31966664 | Int J Clin Exp Pathol | Obeticholic acid improves hepatic steatosis and inflammation by inhibiting NLRP3 inflammasome activation. | 2017 | Details |
| A33049 | 26791024 | Arch Dermatol Res | Hydrogen sulfide diminishes the levels of thymic stromal lymphopoietin in activated mast cells. | 2016 | Details |
| A33760 | 25202950 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | [Effect of free fatty acid on NALP3 inflammasome signaling pathway in THP-1 macrophages]. | 2014 | Details |
| A34150 | 24312444 | PLoS One | Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice. | 2013 | Details |
| A34453 | 23409132 | PLoS One | Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis. | 2013 | Details |
| A34824 | 22515414 | Nutr Metab (Lond) | Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells. | 2012 | Details |
| A34859 | 22411067 | Lab Invest | Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis. | 2012 | Details |
| A43660 | 31162673 | Alcohol Clin Exp Res | Chalcone Derivative L6H21 Reduces EtOH + LPS-Induced Liver Injury Through Inhibition of NLRP3 Inflammasome Activation. | 2019 | Details |
| A44535 | 28314211 | Mol Immunol | The role of Kupffer cells in hepatic diseases. | 2017 | Details |
| A45345 | 25104498 | Am J Physiol Gastrointest Liver Physiol | Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway. | 2014 | Details |
| A45469 | 24397281 | Liver Int | Panaxatriol saponin ameliorated liver injury by acetaminophen via restoring thioredoxin-1 and pro-caspase-12. | 2014 | Details |
| A46259 | 19949375 | Lab Invest | Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet. | 2009 | Details |
| A47121 | 25582105 | J Hepatol | Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in mice. | 2015 | Details |
| A47312 | 17616758 | Am J Clin Nutr | Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium. | 2007 | Details |
| A48640 | 32585073 | J Dig Dis | Role of NLRP3 inflammasome in liver disease. | 2020 | Details |
| A48735 | 30319645 | Front Immunol | Inflammasome: A Double-Edged Sword in Liver Diseases. | 2018 | Details |
| A48813 | 27660175 | J Hepatol | The inflammasome in liver disease. | 2016 | Details |
| A48955 | 23266490 | J Hepatol | Therapeutic strategies in inflammasome mediated diseases of the liver. | 2012 | Details |
| A49264 | 35806450 | Int J Mol Sci | The P2X7R-NLRP3 and AIM2 Inflammasome Platforms Mark the Complexity/Severity of Viral or Metabolic Liver Damage. | 2022 | Details |
| A49284 | 35800450 | Front Pharmacol | Protective Effect of Danshen Zexie Decoction Against Non-Alcoholic Fatty Liver Disease Through Inhibition of ROS/NLRP3/IL-1β Pathway by Nrf2 Signaling Activation. | 2022 | Details |
| A49326 | 35787975 | Cell Mol Gastroenterol Hepatol | Cell-specific deletion of NLRP3 inflammasome identifies myeloid cells as key drivers of liver inflammation and fibrosis in murine steatohepatitis. | 2022 | Details |
| A49396 | 35765026 | J Transl Med | Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome. | 2022 | Details |
| A49642 | 35682887 | Int J Mol Sci | The Role of Autophagy and Pyroptosis in Liver Disorders. | 2022 | Details |
| A49861 | 35616069 | Food Funct | Walnut green husk ethanol extract improves gut microbiota and their metabolites associated with NLRP3 in non-alcoholic steatohepatitis. | 2022 | Details |
| A49883 | 35609854 | J Nutr Biochem | Excess fructose enhances oleatic cytotoxicity via reactive oxygen species production and causes necroptosis in hepatocytes. | 2022 | Details |
| A50015 | 35563377 | Int J Mol Sci | Regulatory Roles of Caspase-11 Non-Canonical Inflammasome in Inflammatory Liver Diseases. | 2022 | Details |
| A50534 | 35350750 | Front Pharmacol | The NLRP3 Inflammasome in Non-Alcoholic Fatty Liver Disease and Steatohepatitis: Therapeutic Targets and Treatment. | 2022 | Details |
| A51164 | 35408890 | Int J Mol Sci | The Role of Endoplasmic Reticulum Stress and NLRP3 Inflammasome in Liver Disorders. | 2022 | Details |
| A51319 | 35644437 | J Ethnopharmacol | Uncovering the mechanism of Huanglian-Wuzhuyu herb pair in treating nonalcoholic steatohepatitis based on network pharmacology and experimental validation. | 2022 | Details |
| A51937 | 33078304 | Arch Pharm Res | Recent insights on modulation of inflammasomes by adipokines: a critical event for the pathogenesis of obesity and metabolism-associated diseases. | 2020 | Details |
| A52085 | 31495623 | J Dairy Sci | Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows. | 2019 | Details |
| A52337 | 28403789 | Curr Med Chem | Metaflammation: Tissue-Specific Alterations of the NLRP3 Inflammasome Platform in Metabolic Syndrome. | 2018 | Details |