Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00559 | 35046901 | Front Endocrinol (Lausanne) | The Nuanced Metabolic Functions of Endogenous FGF21 Depend on the Nature of the Stimulus, Tissue Source, and Experimental Model. | 2022 | Details |
| A00589 | 35038311 | Eur J Endocrinol | Metformin maintains intrahepatic triglyceride content through increased hepatic de novo lipogenesis. | 2022 | Details |
| A00593 | 35036572 | Biol Methods Protoc | Preparation of fatty acid solutions exerts significant impact on experimental outcomes in cell culture models of lipotoxicity. | 2021 | Details |
| A00595 | 35035496 | Evid Based Complement Alternat Med | Lanzhang Granules Ameliorate Nonalcoholic Fatty Liver Disease by Regulating the PPARα Signaling Pathway. | 2022 | Details |
| A00614 | 35028615 | Cell Rep Med | Pharmacodynamic effects of direct AMP kinase activation in humans with insulin resistance and non-alcoholic fatty liver disease: A phase 1b study. | 2021 | Details |
| A00621 | 35024735 | Rom J Morphol Embryol | Triglyceride and glucose index: a useful tool for non-alcoholic liver disease assessed by liver biopsy in patients with metabolic syndrome? | 2022 | Details |
| A00623 | 35024308 | Acta Pharm Sin B | Proteomics and metabolic phenotyping define principal roles for the aryl hydrocarbon receptor in mouse liver. | 2021 | Details |
| A00634 | 35021057 | Immunity | Inflammation in obesity, diabetes, and related disorders. | 2022 | Details |
| A00637 | 35019905 | Biomater Sci | Biodegradable celastrol-loaded albumin nanoparticles ameliorate inflammation and lipid accumulation in diet-induced obese mice. | 2022 | Details |
| A00640 | 35018684 | Phytother Res | Banana green peels extract protects against nonalcoholic fatty liver disease in high-fat-fed mice through modulation of lipid metabolism and inflammation. | 2022 | Details |
| A00645 | 35016619 | BMC Geriatr | Is there an association between non-alcoholic fatty liver disease and cognitive function? A systematic review. | 2022 | Details |
| A00648 | 35015002 | Food Funct | Higher serum vitamin A is associated with a worsened progression of non-alcoholic fatty liver disease in adults: a prospective study. | 2022 | Details |
| A00651 | 35014161 | Diabetes Obes Metab | The metabolic triad of non-alcoholic fatty liver disease, visceral adiposity and type 2 diabetes: Implications for treatment. | 2022 | Details |
| A00652 | 35014156 | Diabetes Obes Metab | Inhibition of 11β-Hydroxysteroid dehydrogenase-1 with AZD4017 in patients with nonalcoholic steatohepatitis or nonalcoholic fatty liver disease: A randomized, double-blind, placebo-controlled, phase II study. | 2022 | Details |
| A00653 | 35014145 | Diabetes Obes Metab | Combination therapy with pioglitazone/exenatide/metformin reduces the prevalence of hepatic fibrosis and steatosis: The efficacy and durability of initial combination therapy for type 2 diabetes (EDICT). | 2022 | Details |
| A00658 | 35013040 | J Oleo Sci | Pink Lotus Essential Oil and Alleviates on Free Fatty Acid Induced Steatosis in HepG2 Cells via PI3K/Akt and NF-κB Pathways. | 2022 | Details |
| A00659 | 35011784 | J Clin Med | Triglyceride Glucose-Waist Circumference Is Superior to the Homeostasis Model Assessment of Insulin Resistance in Identifying Nonalcoholic Fatty Liver Disease in Healthy Subjects. | 2021 | Details |
| A00665 | 35010950 | Nutrients | Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis. | 2021 | Details |
| A00668 | 35009003 | Int J Mol Sci | Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice. | 2022 | Details |
| A00669 | 35008925 | Int J Mol Sci | Non-Alcoholic Steatohepatitis (NASH) and Organokines: What Is Now and What Will Be in the Future. | 2022 | Details |
| A00671 | 35008682 | Int J Mol Sci | Emerging Roles of Calcium Signaling in the Development of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00682 | 35004947 | Hepatobiliary Surg Nutr | The presence of NAFLD in nonobese subjects increased the risk of metabolic abnormalities than obese subjects without NAFLD: a population-based cross-sectional study. | 2021 | Details |
| A00696 | 34999396 | Int Immunopharmacol | Liensinine alleviates high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) through suppressing oxidative stress and inflammation via regulating TAK1/AMPK signaling. | 2022 | Details |
| A00701 | 34998036 | Int Immunopharmacol | Dapagliflozin improves steatohepatitis in diabetic rats via inhibition of oxidative stress and inflammation. | 2022 | Details |
| A00708 | 34993571 | Diabetologia | Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: a randomised controlled trial. | 2022 | Details |
| A00709 | 34993389 | Curr Dev Nutr | Considerations When Choosing High-Fat, High-Fructose, and High-Cholesterol Diets to Induce Experimental Nonalcoholic Fatty Liver Disease in Laboratory Animal Models. | 2021 | Details |
| A00713 | 34992541 | Front Pharmacol | Diammonium Glycyrrhizinate Ameliorates Obesity Through Modulation of Gut Microbiota-Conjugated BAs-FXR Signaling. | 2021 | Details |
| A00724 | 34988690 | Acta Diabetol | Sodium-glucose cotransporter protein-2 inhibitors and glucagon-like peptide-1 receptor agonists versus thiazolidinediones for non-alcoholic fatty liver disease: A network meta-analysis. | 2022 | Details |
| A00725 | 34988225 | Biomed Res Int | Target Deconvolution of Fenofibrate in Nonalcoholic Fatty Liver Disease Using Bioinformatics Analysis. | 2021 | Details |
| A00728 | 34986838 | Cancer Cell Int | STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway. | 2022 | Details |
| A00739 | 34983354 | Endocr Metab Immune Disord Drug Targets | Increasing risk factors of non-alcoholic fatty liver disease, a look into chronic periodontitis and insulin resistance. | 2022 | Details |
| A00741 | 34982494 | J Intern Med | Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice. | 2022 | Details |
| A00744 | 34981470 | Adv Exp Med Biol | The Effect of Herbal Medicine and Natural Bioactive Compounds on Plasma Adiponectin: A Clinical Review. | 2021 | Details |
| A00748 | 34981123 | Biosci Rep | Tandem mass tag-based proteomics analysis of type 2 diabetes mellitus with non-alcoholic fatty liver disease in mice treated with acupuncture. | 2022 | Details |
| A00749 | 34981106 | Food Funct | Supplementation with cyanidin and delphinidin mitigates high fat diet-induced endotoxemia and associated liver inflammation in mice. | 2022 | Details |
| A00750 | 34980714 | J Nutr Sci Vitaminol (Tokyo) | Fasting, Nutrition and Weight Loss: An Approach to Refine Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00758 | 34978141 | Obes Rev | Human microbiome and metabolic health: An overview of systematic reviews. | 2022 | Details |
| A00764 | 34977118 | Front Nutr | Lactational High Fat Diet in Mice Causes Insulin Resistance and NAFLD in Male Offspring Which Is Partially Rescued by Maternal Metformin Treatment. | 2021 | Details |
| A00765 | 34975333 | Int J Biol Sci | Implication of the hepatokine, fibrinogen-like protein 1 in liver diseases, metabolic disorders and cancer: The need to harness its full potential. | 2022 | Details |
| A00768 | 34974284 | Nutrition | Serum concentration of fatty acids in children with obesity and nonalcoholic fatty liver disease. | 2021 | Details |
| A00769 | 34974159 | Mol Metab | CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing. | 2021 | Details |
| A00787 | 34966475 | Oxid Med Cell Longev | Structural and Functional Modulation of Gut Microbiota by Jiangzhi Granules during the Amelioration of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00796 | 34964438 | Elife | Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA. | 2021 | Details |
| A00804 | 34959990 | Nutrients | Dietary Composition and Its Association with Newly Diagnosed Nonalcoholic Fatty Liver Disease and Insulin Resistance. | 2021 | Details |
| A00805 | 34959901 | Nutrients | Role and Treatment of Insulin Resistance in Patients with Chronic Kidney Disease: A Review. | 2021 | Details |
| A00806 | 34959760 | Nutrients | Blood Levels of the SMOC1 Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study. | 2021 | Details |
| A00807 | 34959755 | Nutrients | The Effects of Butyrate on Induced Metabolic-Associated Fatty Liver Disease in Precision-Cut Liver Slices. | 2021 | Details |
| A00808 | 34959747 | Nutrients | High-Fructose, High-Fat Diet Alters Muscle Composition and Fuel Utilization in a Juvenile Iberian Pig Model of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00818 | 34957498 | Diabetes | Hepatic CPT1A Facilitates Liver-Adipose Cross-Talk via Induction of FGF21 in Mice. | 2021 | Details |
| A00819 | 34957487 | Diabetes | Active Brown Adipose Tissue is Associated With a Healthier Metabolic Phenotype in Obesity. | 2021 | Details |
| A00840 | 34951153 | Hepatol Commun | Angiotensin Converting Enzyme-2 Therapy Improves Liver Fibrosis and Glycemic Control in Diabetic Mice With Fatty Liver. | 2021 | Details |
| A00842 | 34950996 | Indian J Gastroenterol | Fetuin-A in newly detected type 2 diabetes mellitus as a marker of non-alcoholic fatty liver disease. | 2021 | Details |
| A00848 | 34950104 | Front Endocrinol (Lausanne) | Efficacy of Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Concurrent Type 2 Diabetes Mellitus and Non-Alcoholic Steatohepatitis: A Review of the Evidence. | 2021 | Details |
| A00850 | 34948230 | Int J Mol Sci | It Is High Time Physicians Thought of Natural Products for Alleviating NAFLD. Is There Sufficient Evidence to Use Them? | 2021 | Details |
| A00857 | 34945016 | J Clin Med | Non-Alcoholic Fatty Liver Disease (NAFLD) and Bariatric/Metabolic Surgery as Its Treatment Option: A Review. | 2021 | Details |
| A00859 | 34944732 | Biomedicines | Therapeutic Opportunities of IL-22 in Non-Alcoholic Fatty Liver Disease: From Molecular Mechanisms to Clinical Applications. | 2021 | Details |
| A00861 | 34944728 | Biomedicines | Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism. | 2021 | Details |
| A00865 | 34944682 | Biomedicines | Metabolic Associated Fatty Liver Disease in Children-From Atomistic to Holistic. | 2021 | Details |
| A00866 | 34944668 | Biomedicines | The Role of Physical Activity in Nonalcoholic and Metabolic Dysfunction Associated Fatty Liver Disease. | 2021 | Details |
| A00869 | 34944525 | Biomolecules | A System-Level Mechanism of Anmyungambi Decoction for Obesity: A Network Pharmacological Approach. | 2021 | Details |
| A00872 | 34943946 | Cells | Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese Ay Mice. | 2021 | Details |
| A00879 | 34943221 | Biology (Basel) | Beta vulgaris L. (Beetroot) Methanolic Extract Prevents Hepatic Steatosis and Liver Damage in T2DM Rats by Hypoglycemic, Insulin-Sensitizing, Antioxidant Effects, and Upregulation of PPARα. | 2021 | Details |
| A00880 | 34943134 | Antioxidants (Basel) | Hepatoprotective Effect of Bee Bread in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Rats: Impact on Oxidative Stress and Inflammation. | 2021 | Details |
| A00895 | 34938205 | Front Physiol | Ectodysplasin A/Ectodysplasin A Receptor System and Their Roles in Multiple Diseases. | 2021 | Details |
| A00897 | 34938090 | Diabetes Metab Syndr Obes | The Predictive Ability of Hepatic Steatosis Index for Gestational Diabetes Mellitus and Large for Gestational Age Infant Compared with Other Noninvasive Indices Among Chinese Pregnancies: A Preliminary Double-center Cohort Study. | 2021 | Details |
| A00901 | 34934197 | Acta Pharmacol Sin | GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis. | 2021 | Details |
| A00916 | 34931080 | Nat Metab | Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity. | 2021 | Details |
| A00918 | 34929996 | Minerva Gastroenterol (Torino) | Evaluation of MACK-3 parameters, metabolic and fibrotic characteristics of non-alcoholic fatty liver disease patients with hypertension. | 2021 | Details |
| A00926 | 34927282 | Drug Dev Res | Schisandrin B ameliorates non-alcoholic liver disease through anti-inflammation activation in diabetic mice. | 2021 | Details |
| A00938 | 34923950 | Curr Mol Pharmacol | Potential Natural Compounds for the Prevention and Treatment of Nonalcoholic Fatty Liver Disease: A Review on Molecular Mechanisms. | 2021 | Details |
| A00940 | 34923463 | Wiad Lek | INSULIN RESISTANCE AS AN INDICATOR OF DIFFERENTIATION FOR THE FORMATION OF RISK GROUPS FOR NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITHOUT TYPE 2 DIABETES MELLITUS, AS A PART OF ONTOLOGICAL MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE. | 2021 | Details |
| A00952 | 34921174 | Sci Rep | Elevated serum S14 levels are associated with more severe liver steatosis by ultrasonography. | 2021 | Details |
| A00956 | 34919684 | J Nutr | A Specifically Tailored Multistrain Probiotic and Micronutrient Mixture Affects Nonalcoholic Fatty Liver Disease-Related Markers in Patients with Obesity after Mini Gastric Bypass Surgery. | 2022 | Details |
| A00958 | 34919135 | JAMA Netw Open | Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials. | 2021 | Details |
| A00960 | 34918493 | Pediatr Obes | MicroRNAs as the promising markers of comorbidities in childhood obesity-A systematic review. | 2021 | Details |
| A00963 | 34917917 | Metabol Open | Emerging roles for stress kinase p38 and stress hormone fibroblast growth factor 21 in NAFLD development. | 2021 | Details |
| A00976 | 34914039 | Indian J Gastroenterol | Endoscopic sleeve gastroplasty - minimally invasive treatment for non-alcoholic fatty liver disease and obesity. | 2021 | Details |
| A00986 | 34909847 | Arq Gastroenterol | MONOCYTE/HDL RATIO IN NON-ALCOHOLIC HEPATIC STEATOSIS. | 2021 | Details |
| A00988 | 34909410 | Psoriasis (Auckl) | Non-Alcoholic Fatty Liver Disease (NAFLD) in Patients with Psoriasis: A Review of the Hepatic Effects of Systemic Therapies. | 2021 | Details |
| A00989 | 34908012 | J Pediatr Gastroenterol Nutr | Non-Invasive Approaches to Estimate Liver Steatosis and Stiffness in Children with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00991 | 34907907 | J Clin Invest | Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease. | 2021 | Details |
| A00992 | 34907906 | J Clin Invest | Dietary sugar restriction reduces hepatic de novo lipogenesis in boys with fatty liver disease. | 2021 | Details |
| A00998 | 34906902 | Biochem Biophys Res Commun | Obesity induced Ext1 reduction mediates the occurrence of NAFLD. | 2021 | Details |
| A01000 | 34906049 | Biochemistry (Mosc) | AMPK/PGC-1α/GLUT4-Mediated Effect of Icariin on Hyperlipidemia-Induced Non-Alcoholic Fatty Liver Disease and Lipid Metabolism Disorder in Mice. | 2021 | Details |
| A01003 | 34905051 | J Clin Endocrinol Metab | Fibrogenesis marker PRO-C3 is higher in advanced liver fibrosis and improves in patients undergoing bariatric surgery. | 2022 | Details |
| A01004 | 34904966 | Am J Gastroenterol | Objectively Measured Physical Activity Is Inversely Associated With Nonalcoholic Fatty Liver Disease: The Rotterdam Study. | 2022 | Details |
| A01021 | 34901163 | Front Mol Biosci | The Role of Notch Signaling Pathway in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01022 | 34900816 | J Diabetes Metab Disord | The effects of high fructose fruits and honey on the serum level of metabolic factors and nonalcoholic fatty liver disease. | 2021 | Details |
| A01042 | 34893351 | Trends Pharmacol Sci | ER stress in obesity pathogenesis and management. | 2021 | Details |
| A01047 | 34890043 | Eur J Clin Invest | The advantages of physical exercise as a preventive strategy against NAFLD in postmenopausal women. | 2022 | Details |
| A01049 | 34888546 | Aging Pathobiol Ther | Hepatic steatosis, a lesion reported in captive aged common marmosets. | 2021 | Details |
| A01051 | 34887672 | Diabetes Metab Syndr Obes | Upregulated lncRNA HCG18 in Patients with Non-Alcoholic Fatty Liver Disease and Its Regulatory Effect on Insulin Resistance. | 2021 | Details |
| A01053 | 34887631 | World J Gastroenterol | Non-alcoholic fatty liver disease in patients with intestinal, pulmonary or skin diseases: Inflammatory cross-talk that needs a multidisciplinary approach. | 2021 | Details |
| A01060 | 34884650 | Int J Mol Sci | Verification of the Impact of Blood Glucose Level on Liver Carcinogenesis and the Efficacy of a Dietary Intervention in a Spontaneous Metabolic Syndrome Model. | 2021 | Details |
| A01061 | 34884625 | Int J Mol Sci | Hypothyroidism-Associated Dyslipidemia: Potential Molecular Mechanisms Leading to NAFLD. | 2021 | Details |
| A01067 | 34881510 | Pediatr Obes | The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial. | 2021 | Details |
| A01074 | 34877910 | Expert Rev Gastroenterol Hepatol | Effects of probiotics on nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2021 | Details |
| A01090 | 34871812 | Clin Gastroenterol Hepatol | Intensive Lifestyle Management Improves Steatosis and Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01095 | 34870551 | Pharm Biol | Ellagic acid protects against non-alcoholic fatty liver disease in streptozotocin-diabetic rats by activating AMPK. | 2022 | Details |
| A01097 | 34870138 | Metabol Open | Metabolic causes and consequences of nonalcoholic fatty liver disease (NAFLD). | 2021 | Details |