Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A01376 | 34769332 | Int J Mol Sci | Association between Equol Production Status and Nonalcoholic Steatohepatitis. | 2021 | Details |
| A01386 | 34764881 | Front Physiol | Green Plant Pigment, Chlorophyllin, Ameliorates Non-alcoholic Fatty Liver Diseases (NAFLDs) Through Modulating Gut Microbiome in Mice. | 2021 | Details |
| A01395 | 34762106 | JAMA | Association of Bariatric Surgery With Major Adverse Liver and Cardiovascular Outcomes in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis. | 2021 | Details |
| A01402 | 34759011 | Drug Metab Dispos | Environmental Chemical Contribution to the Modulation of Bile Acid Homeostasis and Farnesoid X Receptor Signaling. | 2021 | Details |
| A01429 | 34750345 | Sci Rep | Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility. | 2021 | Details |
| A01443 | 34743980 | Eur J Pharmacol | Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms. | 2021 | Details |
| A01446 | 34742934 | Arch Biochem Biophys | The probiotic effects of AB23A on high-fat-diet-induced non-alcoholic fatty liver disease in mice may be associated with suppressing the serum levels of lipopolysaccharides and branched-chain amino acids. | 2021 | Details |
| A01460 | 34740314 | Mol Med | Nuclear receptors: a bridge linking the gut microbiome and the host. | 2021 | Details |
| A01466 | 34737121 | J Mol Cell Cardiol | NAFLD as a continuous driver in the whole spectrum of vascular disease. | 2021 | Details |
| A01474 | 34734433 | J Gastroenterol Hepatol | New perspective on fecal microbiota transplantation in liver diseases. | 2022 | Details |
| A01475 | 34734369 | J Gastrointest Surg | The Role of Gut-Derived Lipopolysaccharides and the Intestinal Barrier in Fatty Liver Diseases. | 2021 | Details |
| A01501 | 34722019 | Cureus | Decoding the Pathophysiology of Non-alcoholic Fatty Liver Disease Progressing to Non-alcoholic Steatohepatitis: A Systematic Review. | 2021 | Details |
| A01513 | 34712528 | Cureus | An Emerging Facet of Diabetes Mellitus: The Nexus of Gastrointestinal Disorders. | 2021 | Details |
| A01516 | 34712025 | World J Gastroenterol | Significance of gut microbiota in alcoholic and non-alcoholic fatty liver diseases. | 2021 | Details |
| A01528 | 34707622 | Front Immunol | Oral Pathobiont-Induced Changes in Gut Microbiota Aggravate the Pathology of Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A01582 | 34685614 | Cells | Gut Microbiota-Related Cellular and Molecular Mechanisms in the Progression of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01584 | 34684698 | Molecules | Natural Aporphine Alkaloids with Potential to Impact Metabolic Syndrome. | 2021 | Details |
| A01623 | 34678296 | Clin Chim Acta | The potential pathophysiological role of altered lipid metabolism and electronegative low-density lipoprotein (LDL) in non-alcoholic fatty liver disease and cardiovascular diseases. | 2021 | Details |
| A01644 | 34670043 | N Engl J Med | Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01655 | 34666025 | Clin Chim Acta | Gut microbiome and metabolic response in non-alcoholic fatty liver disease. | 2021 | Details |
| A01700 | 34650994 | Front Med (Lausanne) | Molecular and Cellular Mediators of the Gut-Liver Axis in the Progression of Liver Diseases. | 2021 | Details |
| A01721 | 34639207 | Int J Mol Sci | Flaxseed Powder Attenuates Non-Alcoholic Steatohepatitis via Modulation of Gut Microbiota and Bile Acid Metabolism through Gut-Liver Axis. | 2021 | Details |
| A01731 | 34634561 | Biomed Pharmacother | Jaboticaba (Myrciaria jaboticaba) powder consumption improves the metabolic profile and regulates gut microbiome composition in high-fat diet-fed mice. | 2021 | Details |
| A01735 | 34632902 | Expert Rev Gastroenterol Hepatol | Investigation of etiology-specific alterations in the gut microbiota in liver cirrhosis. | 2021 | Details |
| A01738 | 34631329 | Biosci Microbiota Food Health | Effects of a high-γ-polyglutamic acid-containing natto diet on liver lipids and cecal microbiota of adult female mice. | 2021 | Details |
| A01765 | 34626589 | J Lipid Res | Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70-/- mice by reducing fat absorption. | 2021 | Details |
| A01771 | 34622234 | Cell Rep Med | Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota. | 2021 | Details |
| A01775 | 34621326 | Evid Based Complement Alternat Med | A Novel Identified Peptide Hormone "Metabolitin" Attenuates Lipid Absorption in the Small Intestine of Diabetic Mice with Nonalcoholic Fatty Liver Disease by Regulating Neurotensin and AMPK Signaling Pathway. | 2021 | Details |
| A01780 | 34620653 | BMJ Open | Effects of an isoenergetic low Glycaemic Index (GI) diet on liver fat accumulation and gut microbiota composition in patients with non-alcoholic fatty liver disease (NAFLD): a study protocol of an efficacy mechanism evaluation. | 2021 | Details |
| A01790 | 34617180 | Bull Exp Biol Med | Taurine Reduces Liver Damage in Non-Alcoholic Fatty Liver Disease Model in Rats by Down-Regulating IL-9 and Tumor Growth Factor TGF-β. | 2021 | Details |
| A01793 | 34615727 | Gut | Novel therapeutic targets for cholestatic and fatty liver disease. | 2021 | Details |
| A01803 | 34609304 | Turk J Gastroenterol | Safety and Effectiveness of Essential Phospholipids Paste in Patients with Non-alcoholic Fatty Liver Disease or Viral Hepatitis. | 2021 | Details |
| A01816 | 34606532 | Food Funct | Beneficial impacts of fermented celery (Apium graveolens L.) juice on obesity prevention and gut microbiota modulation in high-fat diet fed mice. | 2021 | Details |
| A01818 | 34604973 | Eur Rev Med Pharmacol Sci | Multifaceted pathogenesis of liver steatosis in inflammatory bowel disease: a systematic review. | 2021 | Details |
| A01821 | 34604271 | Front Nutr | Mechanism of Paeoniae Radix Alba in the Treatment of Non-alcoholic Fatty Liver Disease Based on Sequential Metabolites Identification Approach, Network Pharmacology, and Binding Affinity Measurement. | 2021 | Details |
| A01838 | 34598315 | Immun Inflamm Dis | Multidirectional facets of obesity management in the metabolic syndrome population after liver transplantation. | 2021 | Details |
| A01840 | 34595203 | Front Nutr | Effects of Oral Vitamin C Supplementation on Liver Health and Associated Parameters in Patients With Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2021 | Details |
| A01868 | 34579068 | Nutrients | The Effect of Probiotics (MCP® BCMC® Strains) on Hepatic Steatosis, Small Intestinal Mucosal Immune Function, and Intestinal Barrier in Patients with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01870 | 34579012 | Nutrients | Positive Effects of Exercise Intervention without Weight Loss and Dietary Changes in NAFLD-Related Clinical Parameters: A Systematic Review and Meta-Analysis. | 2021 | Details |
| A01872 | 34578867 | Nutrients | Amelioration of Hepatic Steatosis in Mice through Bacteroides uniformis CBA7346-Mediated Regulation of High-Fat Diet-Induced Insulin Resistance and Lipogenesis. | 2021 | Details |
| A01897 | 34568090 | Front Cell Infect Microbiol | Disease-Associated Gut Microbiota Reduces the Profile of Secondary Bile Acids in Pediatric Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01902 | 34566663 | Front Pharmacol | Preclinical Evidence of Berberine on Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Animal Studies. | 2021 | Details |
| A01918 | 34563519 | J Lipid Res | Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis. | 2021 | Details |
| A01921 | 34561722 | Eur J Nutr | Effects of β-glucan, probiotics, and synbiotics on obesity-associated colitis and hepatic manifestations in C57BL/6J mice. | 2021 | Details |
| A01945 | 34557498 | Front Med (Lausanne) | Fecal Microbiota Transplantation as a Tool for Therapeutic Modulation of Non-gastrointestinal Disorders. | 2021 | Details |
| A01950 | 34556715 | Sci Rep | Ruminant fat intake improves gut microbiota, serum inflammatory parameter and fatty acid profile in tissues of Wistar rats. | 2021 | Details |
| A01955 | 34555255 | Liver Int | COVID-19, adaptative immune response and metabolic-associated liver disease. | 2021 | Details |
| A01961 | 34552561 | Front Endocrinol (Lausanne) | GLP-1 and Underlying Beneficial Actions in Alzheimer's Disease, Hypertension, and NASH. | 2021 | Details |
| A01966 | 34549558 | Adv Clin Exp Med | A novel therapeutic approach to NASH: Both polyethylene glycol 3350 and lactulose reduce hepatic inflammation in C57BL/6J mice. | 2021 | Details |
| A01969 | 34548598 | Sci Rep | Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis. | 2021 | Details |
| A01993 | 34536264 | Anat Rec (Hoboken) | Network pharmacology-based investigation to explore the effect and mechanism of Erchen decoction against the nonalcoholic fatty liver disease. | 2021 | Details |
| A02001 | 34533882 | Cancer Sci | Gut-liver axis-mediated mechanism of liver cancer: A special focus on the role of gut microbiota. | 2021 | Details |
| A02045 | 34521466 | Trials | Effect of Lycium barbarum polysaccharide supplementation in non-alcoholic fatty liver disease patients: study protocol for a randomized controlled trial. | 2021 | Details |
| A02082 | 34511051 | Benef Microbes | Probiotic and prebiotic interventions for non-alcoholic fatty liver disease: a systematic review and network meta-analysis. | 2021 | Details |
| A02084 | 34511035 | Bioengineered | Lactobacillus johnsonii BS15 combined with abdominal massage on intestinal permeability in rats with nonalcoholic fatty liver and cell biofilm repair. | 2021 | Details |
| A02096 | 34508671 | Lancet Gastroenterol Hepatol | Epidemiology, risk factors, social determinants of health, and current management for non-alcoholic fatty liver disease in sub-Saharan Africa. | 2021 | Details |
| A02112 | 34503151 | Cancers (Basel) | Host-Microbiota Interactions in Liver Inflammation and Cancer. | 2021 | Details |
| A02114 | 34502047 | Int J Mol Sci | Molecular and Pathophysiological Links between Metabolic Disorders and Inflammatory Bowel Diseases. | 2021 | Details |
| A02127 | 34497333 | Sci Rep | Toll-like receptor 1 as a possible target in non-alcoholic fatty liver disease. | 2021 | Details |
| A02128 | 34496884 | Lipids Health Dis | Metformin ameliorates maternal high-fat diet-induced maternal dysbiosis and fetal liver apoptosis. | 2021 | Details |
| A02137 | 34491886 | Gut Microbes | Associations of the gut microbiome with hepatic adiposity in the Multiethnic Cohort Adiposity Phenotype Study. | 2022 | Details |
| A02142 | 34489524 | Int J Obes (Lond) | Leptin resistance before and after obesity: evidence that tissue glucose uptake underlies adipocyte enlargement and liver steatosis/steatohepatitis in Zucker rats from early-life stages. | 2021 | Details |
| A02153 | 34484560 | Oxid Med Cell Longev | Dietary Valine Ameliorated Gut Health and Accelerated the Development of Nonalcoholic Fatty Liver Disease of Laying Hens. | 2021 | Details |
| A02157 | 34482357 | Med Sci Monit | Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02163 | 34479345 | Rev Med Chil | [The role of intestinal microbiota in the development of non-alcoholic fatty liver disease]. | 2021 | Details |
| A02165 | 34478730 | Arch Biochem Biophys | Luteolin alleviates non-alcoholic fatty liver disease in rats via restoration of intestinal mucosal barrier damage and microbiota imbalance involving in gut-liver axis. | 2021 | Details |
| A02176 | 34473644 | Aging (Albany NY) | Activation of the gut microbiota-kynurenine-liver axis contributes to the development of nonalcoholic hepatic steatosis in nondiabetic adults. | 2021 | Details |
| A02186 | 34469716 | Cell Rep | Myricetin supplementation decreases hepatic lipid synthesis and inflammation by modulating gut microbiota. | 2021 | Details |
| A02191 | 34466334 | Cureus | Effective Treatment of Nonalcoholic Fatty Liver Disease Using a Community-Based Weight Management Program. | 2021 | Details |
| A02213 | 34458376 | J Immunol Res | Probiotics Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats via Gut Microbiota/FXR/FGF15 Signaling Pathway. | 2021 | Details |
| A02238 | 34449492 | Medicine (Baltimore) | Gut-flora metabolites is not associated with synchronous carotid artery plaque and non-alcoholic fatty liver disease in asymptomatic adults: A STROBE-compliant article. | 2021 | Details |
| A02245 | 34447812 | World J Clin Cases | Intestinal microbiota participates in nonalcoholic fatty liver disease progression by affecting intestinal homeostasis. | 2021 | Details |
| A02259 | 34444932 | Nutrients | The Other Side of Malnutrition in Inflammatory Bowel Disease (IBD): Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02261 | 34444807 | Nutrients | Bariatric Surgery and Liver Disease: General Considerations and Role of the Gut-Liver Axis. | 2021 | Details |
| A02284 | 34437908 | J Hepatol | Intestinal virome and therapeutic potential of bacteriophages in liver disease. | 2021 | Details |
| A02285 | 34437407 | Toxins (Basel) | Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models and Humans. | 2021 | Details |
| A02299 | 34431511 | Cochrane Database Syst Rev | Vitamin D supplementation for chronic liver diseases in adults. | 2021 | Details |
| A02300 | 34431493 | J Clin Endocrinol Metab | LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in Obese Adults With Modest Hypertriglyceridemia. | 2022 | Details |
| A02309 | 34426119 | Int Immunopharmacol | Rotundic acid ameliorates non-alcoholic steatohepatitis via SREBP-1c/ SCD1 signaling pathway and modulating gut microbiota. | 2021 | Details |
| A02315 | 34422323 | J Clin Transl Sci | Excess dietary fructose does not alter gut microbiota or permeability in humans: A pilot randomized controlled study. | 2021 | Details |
| A02341 | 34411400 | Liver Int | Bile acid dysmetabolism in the gut-microbiota-liver axis under hepatitis C virus infection. | 2021 | Details |
| A02358 | 34404276 | Crit Rev Food Sci Nutr | Intestinal dysbiosis in nonalcoholic fatty liver disease (NAFLD): focusing on the gut-liver axis. | 2021 | Details |
| A02359 | 34403877 | Phytomedicine | A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating gut microbiota and reducing inflammation. | 2021 | Details |
| A02374 | 34399486 | Food Res Int | Protective and ameliorating effects of probiotics against diet-induced obesity: A review. | 2021 | Details |
| A02375 | 34399465 | Food Res Int | Regulatory effects of Lactobacillus fermented black barley on intestinal microbiota of NAFLD rats. | 2021 | Details |
| A02383 | 34395490 | Front Nutr | Broccoli Florets Supplementation Improves Insulin Sensitivity and Alters Gut Microbiome Population-A Steatosis Mice Model Induced by High-Fat Diet. | 2021 | Details |
| A02389 | 34392687 | J Agric Food Chem | Understanding Choline Bioavailability and Utilization: First Step Toward Personalizing Choline Nutrition. | 2021 | Details |
| A02395 | 34389163 | Surgery | The role of bilio-pancreatic limb in nonalcoholic steatohepatitis improvement after duodenal-jejunal bypass in rats. | 2021 | Details |
| A02406 | 34384565 | J Pharmacol Sci | Protective effect of SGL5213, a potent intestinal sodium-glucose cotransporter 1 inhibitor, in nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A02437 | 34371946 | Nutrients | Expression of Jejunal Taste Receptors in Women with Morbid Obesity. | 2021 | Details |
| A02469 | 34360923 | Int J Mol Sci | The Role of Leaky Gut in Nonalcoholic Fatty Liver Disease: A Novel Therapeutic Target. | 2021 | Details |
| A02471 | 34360773 | Int J Mol Sci | Effect of Microbiome on Non-Alcoholic Fatty Liver Disease and the Role of Probiotics, Prebiotics, and Biogenics. | 2021 | Details |
| A02506 | 34348707 | J Nanobiotechnology | Improving the ameliorative effects of berberine and curcumin combination via dextran-coated bilosomes on non-alcohol fatty liver disease in mice. | 2021 | Details |
| A02517 | 34343577 | Metabolism | Intestine-liver crosstalk in Type 2 Diabetes and non-alcoholic fatty liver disease. | 2021 | Details |
| A02521 | 34342168 | Physiol Rep | Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress. | 2021 | Details |
| A02523 | 34341928 | Environ Sci Pollut Res Int | Metronidazole enhances steatosis-related early-stage hepatocarcinogenesis in high fat diet-fed rats through DNA double-strand breaks and modulation of autophagy. | 2021 | Details |
| A02533 | 34338703 | Food Funct | Co-supplementation of camelina oil and a prebiotic is more effective for in improving cardiometabolic risk factors and mental health in patients with NAFLD: a randomized clinical trial. | 2021 | Details |
| A02535 | 34337376 | Metabol Open | The role of zinc in the prevention and treatment of nonalcoholic fatty liver disease. | 2021 | Details |
| A02552 | 34330514 | Clin Nutr ESPEN | Contribution of gut microbiota to nonalcoholic fatty liver disease: Pathways of mechanisms. | 2021 | Details |
| A02585 | 34322121 | Front Immunol | CD8+ T Cells Involved in Metabolic Inflammation in Visceral Adipose Tissue and Liver of Transgenic Pigs. | 2021 | Details |