Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Ursodeoxycholic acid254 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A23138 | 24010096 | Pediatr Gastroenterol Hepatol Nutr | The efficacy of pharmacological treatment in pediatric nonalcoholic Fatty liver disease. | 2012 | Details |
| A23327 | 23868620 | Clin Ter | The treatment with ursodeoxycholic acid in elderly patients affected by NAFLD and metabolic syndrome: a case-control study. | 2014 | Details |
| A23346 | 23853345 | Orv Hetil | [Non-alcoholic fatty liver disease and steatohepatitis]. | 2013 | Details |
| A23413 | 23804416 | Obesity (Silver Spring) | Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner. | 2013 | Details |
| A23505 | 26201789 | Hepatol Int | Impact of combined therapy with alpha-lipoic and ursodeoxycolic acid on nonalcoholic fatty liver disease: double-blind, randomized clinical trial of efficacy and safety. | 2012 | Details |
| A23940 | 23369934 | Food Chem Toxicol | Anti-oxidant and natural killer cell activity of Korean red ginseng (Panax ginseng) and urushiol (Rhus vernicifera Stokes) on non-alcoholic fatty liver disease of rat. | 2013 | Details |
| A24062 | 24933975 | Eksp Klin Gastroenterol | [Efficiency of ursodeoxycholic acid therapy in non-alcoholic fatty liver disease associated with metabolic syndrome]. | 2013 | Details |
| A24184 | 23141894 | Clin Res Hepatol Gastroenterol | Treatment of NASH with ursodeoxycholic acid: cons. | 2012 | Details |
| A24185 | 23141893 | Clin Res Hepatol Gastroenterol | Treatment of NASH with ursodeoxycholic acid: pro. | 2012 | Details |
| A24251 | 23075296 | Ital J Pediatr | Therapeutic options in pediatric non alcoholic fatty liver disease: current status and future directions. | 2012 | Details |
| A24418 | 22919243 | World J Gastroenterol | Efficacy of MK615 for the treatment of patients with liver disorders. | 2012 | Details |
| A24430 | 22902550 | J Hepatol | miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease. | 2012 | Details |
| A24470 | 22864259 | Eur J Gastroenterol Hepatol | Ursodeoxycholic acid for nonalcoholic steatohepatitis. | 2012 | Details |
| A24590 | 22718512 | Mol Biol Rep | Traditional Chinese medicines benefit to nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2012 | Details |
| A24655 | 25755424 | J Clin Exp Hepatol | Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis. | 2012 | Details |
| A24746 | 22541706 | Clin Liver Dis | Nonalcoholic fatty liver disease. | 2012 | Details |
| A25083 | 22183915 | Hepatology | Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease. | 2012 | Details |
| A25123 | 22154224 | Clin Res Hepatol Gastroenterol | Ursodeoxycholic acid with vitamin E in patients with nonalcoholic steatohepatitis: long-term results. | 2011 | Details |
| A25791 | 21452138 | Ther Umsch | [Non-alcoholic steatohepatitis - from NAFLD to MAFLD]. | 2011 | Details |
| A25947 | 21280192 | Liver Transpl | Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts. | 2011 | Details |
| A26006 | 21216209 | Endocrinol Nutr | [Fatty liver and its clinical management in obese adolescents]. | 2011 | Details |
| A26020 | 22629789 | Eksp Klin Gastroenterol | [UDCA in the treatment of nonalcoholic fatty liver disease]. | 2011 | Details |
| A26021 | 22629725 | Eksp Klin Gastroenterol | [UDCA in the treatment of nonalcoholic fatty liver disease]. | 2011 | Details |
| A26026 | 21191681 | Indian J Gastroenterol | Nonalcoholic fatty liver disease in India - a lot done, yet more required! | 2010 | Details |
| A26072 | 21145828 | J Hepatol | A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis. | 2010 | Details |
| A26093 | 21115542 | Gut | Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis. | 2010 | Details |
| A26109 | 21079772 | PLoS One | Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice. | 2010 | Details |
| A26152 | 21033080 | Eksp Klin Gastroenterol | [Hypolipidemic therapy in patients with non-alcoholic fatty liver disease]. | 2010 | Details |
| A26443 | 20460915 | Dig Dis | Bile acids as regulators of hepatic lipid and glucose metabolism. | 2010 | Details |
| A26483 | 20388946 | J Physiol Pharmacol | Therapy of nonalcoholic fatty liver disease: current status. | 2009 | Details |
| A26549 | 20222991 | Lipids Health Dis | NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26761 | 19818312 | Clin Liver Dis | Pharmacologic therapy of non-alcoholic steatohepatitis. | 2009 | Details |
| A26953 | 19473430 | Hepatol Res | The effect of ursodeoxycholic acid on liver regeneration after partial hepatectomy in rats with non-alcoholic fatty liver disease. | 2009 | Details |
| A26984 | 19412008 | J Pediatr Gastroenterol Nutr | Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review. | 2009 | Details |
| A27130 | 21180532 | Therap Adv Gastroenterol | Current status of therapy in nonalcoholic Fatty liver disease. | 2009 | Details |
| A27218 | 18956296 | Semin Liver Dis | Current and emerging therapies in nonalcoholic fatty liver disease. | 2008 | Details |
| A27339 | 18617457 | Orv Hetil | [Non-alcoholic fatty liver disease and cardiovascular risk]. | 2008 | Details |
| A27369 | 18516264 | Ther Clin Risk Manag | Treatment of non-alcoholic fatty liver disease. | 2007 | Details |
| A27424 | 18410557 | Aliment Pharmacol Ther | Review article: current management of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. | 2008 | Details |
| A27430 | 18397387 | Aliment Pharmacol Ther | Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease. | 2008 | Details |
| A27469 | 18330098 | Acta Gastroenterol Belg | Statins in hepatobiliary diseases: effects, indications and risks. | 2008 | Details |
| A27506 | 18241645 | Zhong Xi Yi Jie He Xue Bao | Effectiveness of Danning Tablet in patients with non-alcoholic fatty liver of damp-heat syndrome type: a multicenter randomized controlled trial. | 2008 | Details |
| A27792 | 17420951 | Dig Dis Sci | The clinicopathological profile of Indian patients with nonalcoholic fatty liver disease (NAFLD) is different from that in the West. | 2007 | Details |
| A27852 | 17253541 | Cochrane Database Syst Rev | Bile acids for non-alcoholic fatty liver disease and/or steatohepatitis. | 2007 | Details |
| A28044 | 16610015 | World J Gastroenterol | Treatment of nonalcoholic fatty liver disease. | 2006 | Details |
| A28060 | 16540769 | J Clin Gastroenterol | Therapy of NAFLD: antioxidants and cytoprotective agents. | 2006 | Details |
| A28100 | 16424622 | Indian J Gastroenterol | Vitamin E-based therapy is effective in ameliorating transaminasemia in nonalcoholic fatty liver disease. | 2006 | Details |
| A28112 | 16393299 | Aliment Pharmacol Ther | Review article: Drug therapy for non-alcoholic fatty liver disease. | 2006 | Details |
| A28259 | 15926603 | J Assoc Physicians India | Non-alcoholic steatohepatitis. | 2005 | Details |
| A28339 | 15598336 | Pediatr Transplant | Non-alcoholic steatohepatitis in children. | 2004 | Details |
| A28346 | 15561641 | Best Pract Res Clin Gastroenterol | Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH): treatment. | 2004 | Details |
| A28377 | 15331071 | Clin Liver Dis | Pharmacologic management of nonalcoholic fatty liver disease. | 2004 | Details |
| A28410 | 15144045 | Rev Invest Clin | [An update on non-alcoholic fatty liver disease]. | 2004 | Details |
| A28416 | 15114291 | Ann Hepatol | Treatment of nonalcoholic fatty liver disease. | 2004 | Details |
| A28459 | 14585234 | Curr Treat Options Gastroenterol | Treatment of Nonalcoholic Fatty Liver Disease. | 2003 | Details |
| A28479 | 12739988 | Expert Opin Pharmacother | Current best treatment for non-alcoholic fatty liver disease. | 2003 | Details |
| A28498 | 12508671 | Praxis (Bern 1994) | [Rare, but important chronic liver diseases]. | 2002 | Details |
| A28507 | 12406446 | Best Pract Res Clin Gastroenterol | Treatment of non-alcoholic steatohepatitis. | 2002 | Details |
| A28520 | 12214335 | Rev Gastroenterol Mex | [Non-alcoholic steatohepatitis]. | 2002 | Details |
| A28525 | 12122975 | Rev Gastroenterol Disord | Nonalcoholic fatty liver disease. | 2002 | Details |
| A28842 | 34919247 | Eur Rev Med Pharmacol Sci | A randomized controlled trial comparing the effects of Vitamin E, Ursodeoxycholic acid and Pentoxifylline on Egyptian non-alcoholic steatohepatitis patients. | 2021 | Details |
| A29086 | 34603061 | Front Pharmacol | Berberine Alleviates Non-alcoholic Steatohepatitis Through Modulating Gut Microbiota Mediated Intestinal FXR Activation. | 2021 | Details |
| A29597 | 33817519 | ACS Omega | One-Pot Extraction and Quantification Method for Bile Acids in the Rat Liver by Capillary Liquid Chromatography Tandem Mass Spectrometry. | 2021 | Details |
| A29742 | 33590776 | Gut Microbes | The contribution of gut bacterial metabolites in the human immune signaling pathway of non-communicable diseases. | 2022 | Details |
| A29991 | 33158472 | Best Pract Res Clin Gastroenterol | De novo and recurrent liver disease. | 2020 | Details |
| A30654 | 32039401 | JHEP Rep | Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis. | 2019 | Details |
| A30670 | 32021639 | Nutr Metab (Lond) | Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis. | 2020 | Details |
| A30824 | 31717968 | Int J Mol Sci | The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2. | 2019 | Details |
| A32734 | 27652492 | J Med Chem | Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders. | 2016 | Details |
| A33505 | 25848483 | World J Hepatol | Prevention of hepatocellular carcinoma: Focusing on antioxidant therapy. | 2015 | Details |
| A33998 | 24669237 | Exp Ther Med | Effects of pioglitazone on nonalcoholic steatohepatitis in a patient with anorexia nervosa: A case report. | 2014 | Details |
| A34094 | 24421392 | Mol Cell Biol | c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver. | 2014 | Details |
| A34247 | 23974795 | Mol Pharmacol | Ursodeoxycholyl lysophosphatidylethanolamide inhibits lipoapoptosis by shifting fatty acid pools toward monosaturated and polyunsaturated fatty acids in mouse hepatocytes. | 2013 | Details |
| A35001 | 22013536 | Int J Hepatol | NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA. | 2011 | Details |
| A35109 | 21712950 | Case Rep Gastroenterol | Effective therapy using voglibose for nonalcoholic steatohepatitis in a patient with insufficient dietary and exercise therapy: exploring other treatment possibilities. | 2011 | Details |
| A35113 | 21711424 | Hepatol Res | Ursodeoxycholic acid dose-dependently improves liver injury in rats fed a methionine- and choline-deficient diet. | 2011 | Details |
| A35236 | 21338455 | Hepatol Res | Late diagnosed Wilson disease with hepatic and neurological manifestations. | 2011 | Details |
| A35336 | 21063487 | Hepatol Int | A pilot trial of high-dose ursodeoxycholic acid in nonalcoholic steatohepatitis. | 2010 | Details |
| A35435 | 20683947 | Hepatology | High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial. | 2010 | Details |
| A35887 | 19496180 | Hepatology | Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent. | 2009 | Details |
| A35915 | 19422479 | Liver Int | Effects of ursodeoxycholic acid in combination with vitamin E on adipokines and apoptosis in patients with nonalcoholic steatohepatitis. | 2009 | Details |
| A36250 | 18638709 | Complement Ther Med | The effect of QuYuHuaTanTongLuo Decoction on the non-alcoholic steatohepatitis. | 2008 | Details |
| A36482 | 18042441 | J Cyst Fibros | A single centre experience of liver disease in adults with cystic fibrosis 1995-2006. | 2007 | Details |
| A36669 | 17487265 | Can J Physiol Pharmacol | Combining ursodeoxycholic acid or its NO-releasing derivative NCX-1000 with lipophilic antioxidants better protects mouse hepatocytes against amiodarone toxicity. | 2007 | Details |
| A36711 | 17410287 | J Gastrointestin Liver Dis | Therapeutic options in non-alcoholic steatohepatitis (NASH). Are all agents alike? Results of a preliminary study. | 2007 | Details |
| A36814 | 17205821 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Effects of resolving phlegm method on fibrinolytic status in non-alcoholic steatohepatitis patients of phlegm and blood-stasis syndrome]. | 2006 | Details |
| A36824 | 17162245 | Clin Gastroenterol Hepatol | Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis. | 2006 | Details |
| A36848 | 17105586 | Liver Int | Values and limitations of serum aminotransferases in clinical trials of nonalcoholic steatohepatitis. | 2006 | Details |
| A37382 | 15818751 | World J Gastroenterol | Effects of ursodeoxycholic acid and/or low-calorie diet on steatohepatitis in rats with obesity and hyperlipidemia. | 2005 | Details |
| A37403 | 15754789 | Lijec Vjesn | [Nonalcoholic steatohepatitis in children]. | 2005 | Details |
| A37543 | 15457967 | Ther Umsch | [Alcoholic and non-alcoholic steatohepatitis]. | 2004 | Details |
| A37691 | 15106708 | Indian J Gastroenterol | Assessment of insulin resistance and effect of metformin in nonalcoholic steatohepatitis--a preliminary report. | 2004 | Details |
| A37730 | 14999696 | Hepatology | Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial. | 2004 | Details |
| A37781 | 14679419 | Can J Gastroenterol | Ursodeoxycholic acid and atorvastatin in the treatment of nonalcoholic steatohepatitis. | 2003 | Details |
| A38077 | 12214337 | Rev Gastroenterol Mex | [Treatment of non-alcoholic steatohepatitis (NASH). A comparative study of ursodeoxycholic acid and alpha-tocopherol. A preliminary report]. | 2002 | Details |
| A38085 | 12192203 | J Clin Gastroenterol | Management of nonalcoholic steatohepatitis: an analytic review. | 2002 | Details |
| A38186 | 11944630 | Semin Gastrointest Dis | Diabetes mellitus, obesity, and hepatic steatosis. | 2002 | Details |
| A38220 | 11873108 | J Clin Gastroenterol | Update on nonalcoholic fatty liver disease. | 2002 | Details |
| A38342 | 11495032 | J Hepatol | Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'. | 2001 | Details |
| A38502 | 11097727 | Curr Treat Options Gastroenterol | Non-Alcoholic Steatohepatitis (NASH). | 1999 | Details |