Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A11994 | 30653691 | Hepatology | The Role of Innate Immune Cells in Nonalcoholic Steatohepatitis. | 2019 | Details |
| A11996 | 30653387 | J Womens Health (Larchmt) | Serum Testosterone Level Within Normal Range Is Positively Associated with Nonalcoholic Fatty Liver Disease in Premenopausal but Not Postmenopausal Women. | 2019 | Details |
| A12000 | 30652641 | Curr Pharm Des | Nonalcoholic Fatty Liver Disease in Patients with Polycystic Ovary Syndrome. | 2018 | Details |
| A12014 | 30642871 | Dis Model Mech | Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity. | 2019 | Details |
| A12016 | 30642126 | Int J Mol Sci | Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A12034 | 30631760 | Can J Gastroenterol Hepatol | Changes of the Fatty Acid Profile in Erythrocyte Membranes of Patients following 6-Month Dietary Intervention Aimed at the Regression of Nonalcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A12042 | 30626749 | JCI Insight | The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity. | 2019 | Details |
| A12044 | 30625508 | Exp Clin Endocrinol Diabetes | Selenoprotein P in Patients with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12048 | 30625285 | Annu Rev Pharmacol Toxicol | Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes. | 2019 | Details |
| A12050 | 30623792 | Biomaterials | Intravenous sustained-release nifedipine ameliorates nonalcoholic fatty liver disease by restoring autophagic clearance. | 2019 | Details |
| A12080 | 30611282 | Lipids Health Dis | Concurrent exercise improves insulin resistance and nonalcoholic fatty liver disease by upregulating PPAR-γ and genes involved in the beta-oxidation of fatty acids in ApoE-KO mice fed a high-fat diet. | 2019 | Details |
| A12081 | 30610213 | Eur J Clin Nutr | The effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A12084 | 30609189 | Liver Transpl | Predictors of De Novo Nonalcoholic Fatty Liver Disease After Liver Transplantation and Associated Fibrosis. | 2019 | Details |
| A12086 | 30608932 | PLoS One | High prevalence of nonalcoholic steatohepatitis and abnormal liver stiffness in a young and obese Mexican population. | 2019 | Details |
| A12087 | 30607807 | Infect Dis Ther | A Review of Non-Alcoholic Fatty Liver Disease in HIV-Infected Patients: The Next Big Thing? | 2019 | Details |
| A12092 | 30605883 | Redox Biol | Consumption of decaffeinated coffee protects against the development of early non-alcoholic steatohepatitis: Role of intestinal barrier function. | 2018 | Details |
| A12093 | 30605818 | Environ Pollut | Effects of triphenyl phosphate exposure during fetal development on obesity and metabolic dysfunctions in adult mice: Impaired lipid metabolism and intestinal dysbiosis. | 2018 | Details |
| A12095 | 30605011 | Am J Physiol Gastrointest Liver Physiol | Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice. | 2019 | Details |
| A12102 | 30601337 | Eur J Gastroenterol Hepatol | Serum fetuin-B level is an independent marker for nonalcoholic fatty liver disease in patients with type 2 diabetes. | 2019 | Details |
| A12104 | 30600551 | J Gastroenterol Hepatol | HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease. | 2019 | Details |
| A12107 | 30600295 | Ann Hepatol | Association of Parity in Patients with Chronic Liver Disease. | 2018 | Details |
| A12108 | 30599260 | Free Radic Biol Med | Loss of RIP3 initiates annihilation of high-fat diet initialized nonalcoholic hepatosteatosis: A mechanism involving Toll-like receptor 4 and oxidative stress. | 2018 | Details |
| A12114 | 30596786 | PLoS One | Protective effects of Bacillus probiotics against high-fat diet-induced metabolic disorders in mice. | 2018 | Details |
| A12121 | 30594638 | Biochim Biophys Acta Gene Regul Mech | Role of long non-coding RNAs in metabolic control. | 2018 | Details |
| A12125 | 30592129 | IUBMB Life | Role of vitamin E in nonalcoholic fatty liver disease. | 2018 | Details |
| A12129 | 30590868 | J Gastroenterol Hepatol | Characteristics of non-alcoholic steatohepatitis among lean patients in Japan: Not uncommon and not always benign. | 2019 | Details |
| A12133 | 30589487 | Obes Rev | Crosstalk between nonalcoholic fatty liver disease and cardiometabolic syndrome. | 2018 | Details |
| A12134 | 30588836 | Antioxid Redox Signal | The Antioxidant Effects of Hydroxytyrosol and Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease, in a Clinical Trial: A New Treatment? | 2019 | Details |
| A12142 | 30584407 | J Med Biochem | Are Vaspin and Omentin-1 Related to Insulin Resistance, Blood Pressure and Inflammation in NAFLD Patients? | 2018 | Details |
| A12143 | 30583863 | Biochem Biophys Res Commun | Erythropoietin and long-acting erythropoiesis stimulating agent ameliorate non-alcoholic fatty liver disease by increasing lipolysis and decreasing lipogenesis via EPOR/STAT pathway. | 2018 | Details |
| A12147 | 30582764 | Hepatology | Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. | 2019 | Details |
| A12150 | 30581002 | Biochem Biophys Res Commun | Secreted modular calcium-binding protein 2 promotes high fat diet (HFD)-induced hepatic steatosis through enhancing lipid deposition, fibrosis and inflammation via targeting TGF-β1. | 2018 | Details |
| A12156 | 30578967 | Biochim Biophys Acta Mol Cell Biol Lipids | Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease. | 2018 | Details |
| A12164 | 30577089 | Hepatol Res | Impact of sodium glucose cotransporter 2 inhibitor on histological features and glucose metabolism of non-alcoholic fatty liver disease complicated by diabetes mellitus. | 2019 | Details |
| A12168 | 30576537 | Hum Reprod | Features of the metabolic syndrome in late adolescence are associated with impaired testicular function at 20 years of age. | 2019 | Details |
| A12171 | 30576244 | Am J Physiol Endocrinol Metab | Repeated clodronate-liposome treatment results in neutrophilia and is not effective in limiting obesity-linked metabolic impairments. | 2018 | Details |
| A12174 | 30574460 | Eur Thyroid J | Association between Thyroid-Stimulating Hormone Levels and Non-Alcoholic Fatty Liver Disease Is Not Independent from Metabolic Syndrome Criteria. | 2018 | Details |
| A12197 | 30566676 | J Clin Endocrinol Metab | Hepatic Insulin Extraction in NAFLD Is Related to Insulin Resistance Rather Than Liver Fat Content. | 2019 | Details |
| A12202 | 30563997 | J Clin Exp Hepatol | Biopsy Proven Fibrosis in Non-Alcoholic Fatty Liver Disease: An Analysis of Risk Factors. | 2018 | Details |
| A12205 | 30562976 | J Clin Med | Lean Patients with Non-Alcoholic Fatty Liver Disease Have a Severe Histological Phenotype Similar to Obese Patients. | 2018 | Details |
| A12207 | 30561388 | J Clin Invest | STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis. | 2018 | Details |
| A12218 | 30558790 | Biochem Biophys Res Commun | Upregulation of miR-181a impairs lipid metabolism by targeting PPARα expression in nonalcoholic fatty liver disease. | 2018 | Details |
| A12220 | 30557902 | Diabetes Metab Res Rev | Apolipoprotein CIII and diabetes. Is there a link? | 2019 | Details |
| A12221 | 30557833 | Biomed Pharmacother | Treating hyperuricemia related non-alcoholic fatty liver disease in rats with resveratrol. | 2018 | Details |
| A12223 | 30556145 | Hepatology | Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12226 | 30556036 | Hepatol Commun | A Pathophysiologic Approach Combining Genetics and Insulin Resistance to Predict the Severity of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12232 | 30554468 | Liver Int | Serum adipocyte fatty acid-binding protein levels: An indicator of non-alcoholic fatty liver disease in Chinese individuals. | 2018 | Details |
| A12238 | 30551613 | Nutrients | Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome. | 2018 | Details |
| A12239 | 30551393 | Biomed Pharmacother | Enhanced hepatic glycogen synthesis and suppressed adenosine deaminase activity by lithium attenuates hepatic triglyceride accumulation in nicotine-exposed rats. | 2018 | Details |
| A12248 | 30547890 | Eur Cytokine Netw | Obesity and inflammation. | 2018 | Details |
| A12253 | 30545408 | J Med Case Rep | Acquired partial lipoatrophy as graft-versus-host disease and treatment with metreleptin: two case reports. | 2018 | Details |
| A12259 | 30543441 | Mol Pharm | Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice. | 2018 | Details |
| A12260 | 30542827 | Obes Surg | Long-term Results of Bariatric Surgery for Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis Treatment in Morbidly Obese Japanese Patients. | 2019 | Details |
| A12266 | 30541128 | J Clin Endocrinol Metab | The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet. | 2019 | Details |
| A12279 | 30536914 | J Physiol | Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions. | 2019 | Details |
| A12285 | 30533179 | World J Hepatol | Treating nonalcoholic steatohepatitis with antidiabetic drugs: Will GLP-1 agonists end the struggle? | 2018 | Details |
| A12289 | 30528710 | Dig Liver Dis | Salivary markers of hepato-metabolic comorbidities in pediatric obesity. | 2018 | Details |
| A12300 | 30519965 | Acta Diabetol | A round trip from nonalcoholic fatty liver disease to diabetes: molecular targets to the rescue? | 2018 | Details |
| A12310 | 30504232 | J Lipid Res | Hepatic transcriptome analysis from HFD-fed mice defines a long noncoding RNA regulating cellular cholesterol levels. | 2018 | Details |
| A12330 | 30512987 | Am J Physiol Endocrinol Metab | Estrogen receptor-α signaling maintains immunometabolic function in males and is obligatory for exercise-induced amelioration of nonalcoholic fatty liver. | 2018 | Details |
| A12339 | 30500887 | Endocr Rev | Reproductive Endocrinology of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12348 | 30496690 | Postgrad Med | Clinical workup of fatty liver for the primary care provider. | 2018 | Details |
| A12371 | 30483536 | JGH Open | Vitamin D supplementation in patients with nonalcoholic fatty liver disease: A randomized controlled trial. | 2017 | Details |
| A12373 | 30482910 | Nat Rev Gastroenterol Hepatol | The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2019 | Details |
| A12378 | 30477827 | Complement Ther Med | The effects of Zataria multiflora Boiss. (Shirazi thyme) on nonalcoholic fatty liver disease and insulin resistance: A randomized double-blind placebo-controlled clinical trial. | 2018 | Details |
| A12379 | 30477455 | BMC Endocr Disord | Treatment with PBI-4050 in patients with Alström syndrome: study protocol for a phase 2, single-Centre, single-arm, open-label trial. | 2018 | Details |
| A12384 | 30474288 | Obes Rev | Sarcopenia in patients with non-alcoholic fatty liver disease: is it a clinically significant entity? | 2018 | Details |
| A12390 | 30473057 | Metabolism | Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models. | 2018 | Details |
| A12391 | 30473026 | Life Sci | p53 as a double-edged sword in the progression of non-alcoholic fatty liver disease. | 2018 | Details |
| A12397 | 30472683 | Gut | Alcoholic and non-alcoholic fatty liver disease and associations with coronary artery calcification: evidence from the Kangbuk Samsung Health Study. | 2018 | Details |
| A12401 | 30470912 | Diabetologia | Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus. | 2018 | Details |
| A12403 | 30469392 | J Clin Med | Bidirectional Association between Nonalcoholic Fatty Liver Disease and Gallstone Disease: A Cohort Study. | 2018 | Details |
| A12406 | 30468651 | Front Biosci (Landmark Ed) | Fructose at the crossroads of the metabolic syndrome and obesity epidemics. | 2019 | Details |
| A12410 | 30466956 | Clin Nutr | Lean non-alcoholic fatty liver disease. | 2018 | Details |
| A12414 | 30465824 | Free Radic Biol Med | Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia. | 2018 | Details |
| A12424 | 30459251 | Diabetes | Targeting Metabolism, Insulin Resistance, and Diabetes to Treat Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12426 | 30458848 | Lipids Health Dis | A longitudinal epidemiological study on the triglyceride and glucose index and the incident nonalcoholic fatty liver disease. | 2018 | Details |
| A12431 | 30457913 | Am J Physiol Endocrinol Metab | Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity. | 2018 | Details |
| A12434 | 30456918 | Diabetes Obes Metab | Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis? | 2018 | Details |
| A12435 | 30455723 | Nutr Metab (Lond) | Association of sex hormone-binding globulin with nonalcoholic fatty liver disease in Chinese adults. | 2018 | Details |
| A12440 | 30454891 | Biochem Biophys Res Commun | Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress. | 2018 | Details |
| A12442 | 30454829 | Clin Liver Dis | Will Studies in Nonalcoholic Steatohepatitis Help Manage Alcoholic Steatohepatitis? | 2019 | Details |
| A12444 | 30454678 | Mutat Res Rev Mutat Res | Epigenetics: An emerging field in the pathogenesis of nonalcoholic fatty liver disease. | 2018 | Details |
| A12447 | 30453950 | BMC Complement Altern Med | Evaluation of the effect of Lactobacillus reuteri V3401 on biomarkers of inflammation, cardiovascular risk and liver steatosis in obese adults with metabolic syndrome: a randomized clinical trial (PROSIR). | 2018 | Details |
| A12449 | 30453660 | Nutrients | Gut Permeability Might be Improved by Dietary Fiber in Individuals with Nonalcoholic Fatty Liver Disease (NAFLD) Undergoing Weight Reduction. | 2018 | Details |
| A12457 | 30447037 | Diabetes Obes Metab | Effect of canagliflozin treatment on hepatic triglyceride content and glucose metabolism in patients with type 2 diabetes. | 2018 | Details |
| A12459 | 30446669 | Nat Commun | Serotonin signals through a gut-liver axis to regulate hepatic steatosis. | 2018 | Details |
| A12462 | 30445800 | Cancers (Basel) | Lipid Metabolic Reprogramming in Hepatocellular Carcinoma. | 2018 | Details |
| A12463 | 30445758 | Children (Basel) | Extracellular Vesicles: A Potential Novel Regulator of Obesity and Its Associated Complications. | 2018 | Details |
| A12471 | 30441981 | Vnitr Lek | Future of pharmacological treatment of non-alcoholic steatohepatitis in terms of key pathophysiological mechanisms. | 2019 | Details |
| A12473 | 30431613 | Medicine (Baltimore) | The associations among Helicobacter pylori infection, white blood cell count and nonalcoholic fatty liver disease in a large Chinese population. | 2018 | Details |
| A12474 | 30431378 | Curr Med Res Opin | Severe nonalcoholic steatohepatitis and type 2 diabetes: liver histology after weight loss therapy in a randomized clinical trial. | 2018 | Details |
| A12486 | 30428868 | Lipids Health Dis | Changes in peroxisome proliferator-activated receptor alpha target gene expression in peripheral blood mononuclear cells associated with non-alcoholic fatty liver disease. | 2018 | Details |
| A12487 | 30428692 | Diab Vasc Dis Res | Association of glucagon-to-insulin ratio and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. | 2018 | Details |
| A12492 | 30425763 | J Clin Med Res | Prevalence and Risk Factors of Elevated Liver Enzymes in Japanese Women With Polycystic Ovary Syndrome. | 2018 | Details |
| A12494 | 30425219 | Indian J Med Res | Prevalence, clinical & biochemical correlates of non-alcoholic fatty liver disease in overweight adolescents. | 2018 | Details |
| A12496 | 30422676 | Am J Respir Crit Care Med | Obstructive Sleep Apnea, Hypoxia, and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12502 | 30417996 | Pak J Biol Sci | Comparative Study of Orange and its Main Bioactive Constituents as Remedy for Non-alcoholic Fatty Liver in Rats. | 2018 | Details |
| A12505 | 30415572 | Orv Hetil | [Non-alcoholic fatty liver disease - a summary and update based on the EASL-EASD-EASO Clinical Practice Guidelines of 2016]. | 2018 | Details |
| A12506 | 30415544 | J Agric Food Chem | Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. | 2018 | Details |