Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A07659 | 32405967 | J Gastrointest Cancer | Non-hepatic Cancers Independently Predict Liver Decompensation Events. | 2021 | Details |
| A07660 | 32405182 | J Clin Exp Hepatol | Natural History of Simple Steatosis or Nonalcoholic Fatty Liver. | 2019 | Details |
| A07661 | 32405181 | J Clin Exp Hepatol | Natural History of Non-Alcoholic Fatty Liver Disease: A Study With Paired Liver Biopsies. | 2019 | Details |
| A07663 | 32405177 | J Clin Exp Hepatol | NASH-inducing Diets in Göttingen Minipigs. | 2019 | Details |
| A07671 | 32399892 | Endocrine | Albumin binding function is a novel biomarker for early liver damage and disease progression in non-alcoholic fatty liver disease. | 2020 | Details |
| A07672 | 32398673 | Nat Commun | Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis. | 2020 | Details |
| A07673 | 32398489 | Eur J Gastroenterol Hepatol | Optimal thresholds for ultrasound attenuation parameter in the evaluation of hepatic steatosis severity: evidence from a cohort of patients with biopsy-proven fatty liver disease. | 2021 | Details |
| A07675 | 32396836 | Trends Genet | The Epigenetic Drug Discovery Landscape for Metabolic-associated Fatty Liver Disease. | 2020 | Details |
| A07677 | 32396414 | Aging Male | Non-invasive diagnosis of nonalcoholic fatty liver disease: impact of age and other risk factors. | 2020 | Details |
| A07679 | 32394476 | Hepatology | Hepatic Molecular Signatures Highlight the Sexual Dimorphism of Nonalcoholic Steatohepatitis (NASH). | 2020 | Details |
| A07680 | 32392802 | Int J Mol Sci | Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats. | 2020 | Details |
| A07683 | 32392051 | J Med Chem | 6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07687 | 32390698 | World J Gastroenterol | Macrophages in metabolic associated fatty liver disease. | 2020 | Details |
| A07700 | 32387227 | Metabolism | Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver disease. | 2020 | Details |
| A07701 | 32386798 | Clin Res Hepatol Gastroenterol | LUM is the hub gene of advanced fibrosis in nonalcoholic fatty liver disease patients. | 2020 | Details |
| A07703 | 32385406 | Sci Rep | Pemafibrate, a selective PPARα modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content. | 2020 | Details |
| A07705 | 32384501 | Medicine (Baltimore) | Vitamin D supplementation for nonalcoholic fatty liver disease in type 2 diabetes mellitus: A protocol for a systematic review and meta-analysis. | 2020 | Details |
| A07707 | 32383295 | Aliment Pharmacol Ther | Review article: the emerging role of genetics in precision medicine for patients with non-alcoholic steatohepatitis. | 2020 | Details |
| A07708 | 32382557 | Biomed Res Int | A Candidate Drug for Nonalcoholic Fatty Liver Disease: A Review of Pharmacological Activities of Polygoni Multiflori Radix. | 2020 | Details |
| A07710 | 32382264 | Gastroenterol Res Pract | Interface Hepatitis over Grade 2 May Differentiate Chronic Inflammation Associated with CHB from NAFLD in the Early Stage. | 2020 | Details |
| A07717 | 32377814 | Eur Radiol | Liver extracellular volume fraction values obtained with magnetic resonance imaging can quantitatively stage liver fibrosis: a validation study in monkeys with nonalcoholic steatohepatitis. | 2020 | Details |
| A07718 | 32377366 | BMJ Open Gastroenterol | Antitumour necrosis factor-α agents and development of new-onset cirrhosis or non-alcoholic fatty liver disease: a retrospective cohort. | 2020 | Details |
| A07720 | 32376414 | J Hepatol | Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation. | 2020 | Details |
| A07723 | 32376236 | Ann Hepatol | Blood lead level is associated with advanced liver fibrosis in patients with non-alcoholic fatty liver disease: A nationwide survey (NHANES 2011-2016). | 2020 | Details |
| A07728 | 32374676 | Am J Physiol Cell Physiol | New aspects of hepatic endothelial cells in physiology and nonalcoholic fatty liver disease. | 2020 | Details |
| A07737 | 32370249 | Biology (Basel) | The Role of the Histone Methyltransferase EZH2 in Liver Inflammation and Fibrosis in STAM NASH Mice. | 2020 | Details |
| A07745 | 32366854 | Sci Rep | Novel Combinatorial Regimen of Garcinol and Curcuminoids for Non-alcoholic Steatohepatitis (NASH) in Mice. | 2020 | Details |
| A07748 | 32365632 | Cells | L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men. | 2020 | Details |
| A07749 | 32365537 | Cells | EX-527 Prevents the Progression of High-Fat Diet-Induced Hepatic Steatosis and Fibrosis by Upregulating SIRT4 in Zucker Rats. | 2020 | Details |
| A07750 | 32365405 | J Gastroenterol Hepatol | Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of non-alcoholic steatohepatitis. | 2020 | Details |
| A07753 | 32363890 | Am J Physiol Gastrointest Liver Physiol | Immune modulating effects of additional supplementation of estradiol combined with testosterone in murine testosterone-deficient NAFLD model. | 2020 | Details |
| A07756 | 32363320 | Hepatol Commun | Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07758 | 32363318 | Hepatol Commun | Differential Associations of Circulating MicroRNAs With Pathogenic Factors in NAFLD. | 2020 | Details |
| A07764 | 32360826 | Clin Gastroenterol Hepatol | Decreased Quality of Life Is Significantly Associated With Body Composition in Patients With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07766 | 32360810 | Clin Gastroenterol Hepatol | Women Have a Lower Risk of Nonalcoholic Fatty Liver Disease but a Higher Risk of Progression vs Men: A Systematic Review and Meta-analysis. | 2020 | Details |
| A07767 | 32360804 | Clin Gastroenterol Hepatol | Intragastric Balloon Placement Induces Significant Metabolic and Histologic Improvement in Patients With Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07769 | 32360434 | J Hepatol | Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages☆. | 2020 | Details |
| A07772 | 32359748 | Clin Nutr ESPEN | Diagnostic of hepatic fibrosis with the XL probe of the Fibroscan versus biopsies in patients candidates to bariatric surgery. | 2020 | Details |
| A07777 | 32357501 | Nutrients | Assessing Non-Invasive Liver Function in Patients with Intestinal Failure Receiving Total Parenteral Nutrition-Results from the Prospective PNLiver Trial. | 2020 | Details |
| A07781 | 32355844 | Ann Transl Med | The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis. | 2020 | Details |
| A07782 | 32355752 | Ann Transl Med | Shorter leucocyte telomere length as a potential biomarker for nonalcoholic fatty liver disease-related advanced fibrosis in T2DM patients. | 2020 | Details |
| A07788 | 32354858 | Diabetes | The Effects of B1344, a Novel Fibroblast Growth Factor 21 Analog, on Nonalcoholic Steatohepatitis in Nonhuman Primates. | 2020 | Details |
| A07792 | 32353483 | J Hepatol | Standardisation of diet and exercise in clinical trials of NAFLD-NASH: Recommendations from the Liver Forum. | 2020 | Details |
| A07796 | 32353039 | PLoS Med | Metabolic risk factors and incident advanced liver disease in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis of population-based observational studies. | 2020 | Details |
| A07798 | 32352687 | Clin Transl Gastroenterol | Accuracy of Noninvasive Fibrosis Scoring Systems in African American and White Patients With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07803 | 32351286 | World J Gastroenterol | Determining the role for uric acid in non-alcoholic steatohepatitis development and the utility of urate metabolites in diagnosis: An opinion review. | 2020 | Details |
| A07809 | 32349939 | Ann Hepatol | Epidemiology and pathophysiology of the association between NAFLD and metabolically healthy or metabolically unhealthy obesity. | 2020 | Details |
| A07810 | 32349708 | BMC Gastroenterol | High incidence of hepatocellular carcinoma and cirrhotic complications in patients with psychiatric illness: a territory-wide cohort study. | 2020 | Details |
| A07820 | 32345506 | Rev Gastroenterol Mex (Engl Ed) | Hepatocellular carcinoma in the noncirrhotic liver: Clinical features and outcomes in Veracruz, Mexico. | 2020 | Details |
| A07823 | 32344559 | Metabolites | Distinguishing NASH Histological Severity Using a Multiplatform Metabolomics Approach. | 2020 | Details |
| A07827 | 32343209 | Radiology | Advanced MRI of Liver Fibrosis and Treatment Response in a Rat Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07829 | 32342668 | Liver Int | Attenuated effect of PNPLA3 on hepatic fibrosis by HSD17B13 in Japanese patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A07831 | 32341228 | Saudi J Gastroenterol | Prevalence of biopsy-proven nonalcoholic fatty liver among patients with gallstone disease. | 2020 | Details |
| A07833 | 32340286 | Int J Mol Sci | Nutrition and Genetics in NAFLD: The Perfect Binomium. | 2020 | Details |
| A07835 | 32339855 | Eur J Med Chem | Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment. | 2020 | Details |
| A07841 | 32337818 | Hepatol Res | Diagnostic accuracy of FibroScan-AST score to identify non-alcoholic steatohepatitis with significant activity and fibrosis in Japanese patients with non-alcoholic fatty liver disease: Comparison between M and XL probes. | 2020 | Details |
| A07842 | 32337667 | Dig Dis Sci | How Good Are Controlled Attenuation Parameter Scores from Fibroscan to Assess Steatosis, NASH, and Fibrosis? | 2020 | Details |
| A07847 | 32336033 | J Dig Dis | Non-obese patients with nonalcoholic fatty liver disease may use a lower liver stiffness cut-off to assess fibrosis stages. | 2020 | Details |
| A07855 | 32333454 | J Card Surg | Association between high dose catecholamine support and liver dysfunction following cardiac surgery. | 2020 | Details |
| A07856 | 32333452 | J Gastroenterol Hepatol | Metabolic profiles and fibrosis of nonalcoholic fatty liver disease in the elderly: A community-based study. | 2020 | Details |
| A07859 | 32331389 | Cells | The P2X7 Receptor and NLRP3 Axis in Non-Alcoholic Fatty Liver Disease: A Brief Review. | 2020 | Details |
| A07860 | 32331364 | Cells | The Emerging Role of MicroRNAs in NAFLD: Highlight of MicroRNA-29a in Modulating Oxidative Stress, Inflammation, and Beyond. | 2020 | Details |
| A07861 | 32331258 | Nutrients | Lemon Balm and Its Constituent, Rosmarinic Acid, Alleviate Liver Damage in an Animal Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07862 | 32330605 | J Hepatol | TGF-β1-driven reduction of cytoglobin leads to oxidative DNA damage in stellate cells during non-alcoholic steatohepatitis. | 2020 | Details |
| A07863 | 32330604 | J Hepatol | Animal models for liver disease - A practical approach for translational research. | 2020 | Details |
| A07871 | 32328797 | J Gastroenterol | Nonalcoholic fatty liver disease: impact on healthcare resource utilization, liver transplantation and mortality in a large, integrated healthcare system. | 2020 | Details |
| A07876 | 32326098 | Int J Mol Sci | LncRNAs Act as a Link between Chronic Liver Disease and Hepatocellular Carcinoma. | 2020 | Details |
| A07882 | 32324317 | J Cell Mol Med | GRHL2 induces liver fibrosis and intestinal mucosal barrier dysfunction in non-alcoholic fatty liver disease via microRNA-200 and the MAPK pathway. | 2020 | Details |
| A07884 | 32323349 | Aliment Pharmacol Ther | The PNPLA3 rs738409 GG genotype is associated with poorer prognosis in 239 patients with autoimmune hepatitis. | 2020 | Details |
| A07892 | 32319718 | J Intern Med | Prevalence, characteristics and mortality outcomes of obese, nonobese and lean NAFLD in the United States, 1999-2016. | 2020 | Details |
| A07898 | 32317687 | Sci Rep | Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic steatohepatitis. | 2020 | Details |
| A07899 | 32317586 | Eur J Gastroenterol Hepatol | African Americans have a distinct clinical and histologic profile with lower prevalence of NASH and advanced fibrosis relative to Caucasians. | 2021 | Details |
| A07900 | 32317584 | Eur J Gastroenterol Hepatol | De-novo nonalcoholic fatty liver disease at 5 years after liver transplantation: prevalence and predictive factors. | 2021 | Details |
| A07901 | 32317079 | BMB Rep | GPx7 ameliorates non-alcoholic steatohepatitis by regulating oxidative stress. | 2020 | Details |
| A07902 | 32316984 | BMC Health Serv Res | Protocol for a randomised trial testing a community fibrosis assessment service for patients with suspected non-alcoholic fatty liver disease: LOCal assessment and triage evaluation of non-alcoholic fatty liver disease (LOCATE-NAFLD). | 2020 | Details |
| A07903 | 32316690 | Cells | Noninvasive Diagnosis of NAFLD and NASH. | 2020 | Details |
| A07904 | 32316419 | Int J Mol Sci | Sweroside Prevents Non-Alcoholic Steatohepatitis by Suppressing Activation of the NLRP3 Inflammasome. | 2020 | Details |
| A07905 | 32316235 | J Clin Med | The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis. | 2020 | Details |
| A07913 | 32312927 | Pol Przegl Chir | Prevalence of non-alcoholic fatty liver disease and hypercholesterolemia in patients with gallstone disease undergoing laparoscopic cholecystectomy. | 2019 | Details |
| A07917 | 32311490 | Free Radic Biol Med | Targeting DUSP7 signaling alleviates hepatic steatosis, inflammation and oxidative stress in high fat diet (HFD)-fed mice via suppression of TAK1. | 2020 | Details |
| A07923 | 32307859 | Hepatol Res | Non-invasive diagnosis of non-alcoholic steatohepatitis and advanced fibrosis in Japan: A targeted literature review. | 2020 | Details |
| A07931 | 32306651 | Zhonghua Gan Zang Bing Za Zhi | [Characteristics, diagnostic and therapeutic strategies for chronic hepatitis B combined with non-alcoholic fatty liver disease]. | 2020 | Details |
| A07932 | 32306650 | Zhonghua Gan Zang Bing Za Zhi | [Emphasis on clinical study of heterogeneity of non-alcoholic fatty liver disease]. | 2020 | Details |
| A07934 | 32306299 | Obes Surg | The Impact of Bariatric Surgery on Hepatic Function and Predictors of Liver Steatosis and Fibrosis. | 2020 | Details |
| A07935 | 32305562 | Cell Mol Gastroenterol Hepatol | SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells. | 2020 | Details |
| A07936 | 32305523 | Life Sci | Cystathionine gamma-lyase/H2S system suppresses hepatic acetyl-CoA accumulation and nonalcoholic fatty liver disease in mice. | 2020 | Details |
| A07941 | 32303531 | BMJ Open Diabetes Res Care | Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population. | 2020 | Details |
| A07944 | 32303161 | Curr Pharm Des | Semi-Quantitative Ultrasonographic Evaluation of NAFLD. | 2020 | Details |
| A07955 | 32300166 | Sci Rep | Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity. | 2020 | Details |
| A07959 | 32298766 | J Hepatol | Lytic cell death in metabolic liver disease. | 2020 | Details |
| A07960 | 32298765 | J Hepatol | Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort☆. | 2020 | Details |
| A07963 | 32298002 | Aliment Pharmacol Ther | Accurate non-invasive diagnosis and staging of non-alcoholic fatty liver disease using the urinary steroid metabolome. | 2020 | Details |
| A07965 | 32297157 | Virol Sin | Effect of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 Alpha Variants on Spontaneous Clearance and Fibrosis Progression during Hepatitis C Virus Infection in Moroccan Patients. | 2020 | Details |
| A07967 | 32295224 | Cells | Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis. | 2020 | Details |
| A07971 | 32293289 | BMC Gastroenterol | The Enhanced Liver Fibrosis test is associated with liver-related outcomes in postmenopausal women with risk factors for liver disease. | 2020 | Details |
| A07978 | 32291578 | Indian J Gastroenterol | Gut microbiota abnormalities, small intestinal bacterial overgrowth, and non-alcoholic fatty liver disease: An emerging paradigm. | 2020 | Details |
| A07979 | 32291277 | Diabetes Care | Effects of Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide on Biomarkers of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes. | 2020 | Details |
| A07986 | 32289535 | Clin Gastroenterol Hepatol | Cost Effectiveness of Different Strategies for Detecting Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Based on United States Health Care System. | 2020 | Details |
| A07999 | 32283679 | J Clin Med | Diagnosis of Non-Alcoholic Fatty Liver Disease (NAFLD) Is Independently Associated with Cardiovascular Risk in a Large Austrian Screening Cohort. | 2020 | Details |
| A08000 | 32283406 | Environ Pollut | Long-term bisphenol S exposure aggravates non-alcoholic fatty liver by regulating lipid metabolism and inducing endoplasmic reticulum stress response with activation of unfolded protein response in male zebrafish. | 2020 | Details |