Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A12181 | 30573200 | Arch Med Res | Roles of Autophagy and Protein Kinase C-epsilon in Lipid Metabolism of Nonalcoholic Fatty Liver Cell Models. | 2018 | Details |
| A12197 | 30566676 | J Clin Endocrinol Metab | Hepatic Insulin Extraction in NAFLD Is Related to Insulin Resistance Rather Than Liver Fat Content. | 2019 | Details |
| A12202 | 30563997 | J Clin Exp Hepatol | Biopsy Proven Fibrosis in Non-Alcoholic Fatty Liver Disease: An Analysis of Risk Factors. | 2018 | Details |
| A12205 | 30562976 | J Clin Med | Lean Patients with Non-Alcoholic Fatty Liver Disease Have a Severe Histological Phenotype Similar to Obese Patients. | 2018 | Details |
| A12206 | 30562559 | Biochim Biophys Acta Mol Basis Dis | Hepatic mTOR-AKT2-Insig2 signaling pathway contributes to the improvement of hepatic steatosis after Roux-en-Y Gastric Bypass in mice. | 2018 | Details |
| A12207 | 30561388 | J Clin Invest | STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis. | 2018 | Details |
| A12210 | 30561027 | Aliment Pharmacol Ther | Impact of a structured lifestyle programme on patients with metabolic syndrome complicated by non-alcoholic fatty liver disease. | 2018 | Details |
| A12217 | 30559024 | J Pediatr | Prevalence of Nonalcoholic Fatty Liver Disease in Children with Obesity. | 2018 | Details |
| A12218 | 30558790 | Biochem Biophys Res Commun | Upregulation of miR-181a impairs lipid metabolism by targeting PPARα expression in nonalcoholic fatty liver disease. | 2018 | Details |
| A12220 | 30557902 | Diabetes Metab Res Rev | Apolipoprotein CIII and diabetes. Is there a link? | 2019 | Details |
| A12221 | 30557833 | Biomed Pharmacother | Treating hyperuricemia related non-alcoholic fatty liver disease in rats with resveratrol. | 2018 | Details |
| A12223 | 30556145 | Hepatology | Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12226 | 30556036 | Hepatol Commun | A Pathophysiologic Approach Combining Genetics and Insulin Resistance to Predict the Severity of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12228 | 30555521 | Nutr Metab (Lond) | Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice. | 2018 | Details |
| A12232 | 30554468 | Liver Int | Serum adipocyte fatty acid-binding protein levels: An indicator of non-alcoholic fatty liver disease in Chinese individuals. | 2018 | Details |
| A12238 | 30551613 | Nutrients | Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome. | 2018 | Details |
| A12239 | 30551393 | Biomed Pharmacother | Enhanced hepatic glycogen synthesis and suppressed adenosine deaminase activity by lithium attenuates hepatic triglyceride accumulation in nicotine-exposed rats. | 2018 | Details |
| A12248 | 30547890 | Eur Cytokine Netw | Obesity and inflammation. | 2018 | Details |
| A12253 | 30545408 | J Med Case Rep | Acquired partial lipoatrophy as graft-versus-host disease and treatment with metreleptin: two case reports. | 2018 | Details |
| A12259 | 30543441 | Mol Pharm | Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice. | 2018 | Details |
| A12260 | 30542827 | Obes Surg | Long-term Results of Bariatric Surgery for Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis Treatment in Morbidly Obese Japanese Patients. | 2019 | Details |
| A12266 | 30541128 | J Clin Endocrinol Metab | The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet. | 2019 | Details |
| A12278 | 30537110 | Mol Nutr Food Res | Combination of Whole Grapeseed Flour and Newly Isolated Kefir Lactic Acid Bacteria Reduces High-Fat-Induced Hepatic Steatosis. | 2018 | Details |
| A12279 | 30536914 | J Physiol | Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions. | 2019 | Details |
| A12285 | 30533179 | World J Hepatol | Treating nonalcoholic steatohepatitis with antidiabetic drugs: Will GLP-1 agonists end the struggle? | 2018 | Details |
| A12289 | 30528710 | Dig Liver Dis | Salivary markers of hepato-metabolic comorbidities in pediatric obesity. | 2018 | Details |
| A12293 | 30526624 | J Transl Med | L-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice. | 2018 | Details |
| A12296 | 30521580 | PLoS One | E4orf1: A protein for enhancing glucose uptake despite impaired proximal insulin signaling. | 2018 | Details |
| A12297 | 30520566 | Obesity (Silver Spring) | Pegbelfermin (BMS-986036), PEGylated FGF21, in Patients with Obesity and Type 2 Diabetes: Results from a Randomized Phase 2 Study. | 2018 | Details |
| A12300 | 30519965 | Acta Diabetol | A round trip from nonalcoholic fatty liver disease to diabetes: molecular targets to the rescue? | 2018 | Details |
| A12310 | 30504232 | J Lipid Res | Hepatic transcriptome analysis from HFD-fed mice defines a long noncoding RNA regulating cellular cholesterol levels. | 2018 | Details |
| A12312 | 30503530 | Clin Biochem | A simpler diagnostic formula for screening nonalcoholic fatty liver disease. | 2018 | Details |
| A12317 | 30516845 | Hepatology | Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis. | 2019 | Details |
| A12330 | 30512987 | Am J Physiol Endocrinol Metab | Estrogen receptor-α signaling maintains immunometabolic function in males and is obligatory for exercise-induced amelioration of nonalcoholic fatty liver. | 2018 | Details |
| A12335 | 30510243 | Exp Mol Med | Sodium butyrate reduces high-fat diet-induced non-alcoholic steatohepatitis through upregulation of hepatic GLP-1R expression. | 2018 | Details |
| A12339 | 30500887 | Endocr Rev | Reproductive Endocrinology of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12348 | 30496690 | Postgrad Med | Clinical workup of fatty liver for the primary care provider. | 2018 | Details |
| A12363 | 30484310 | J Agric Food Chem | Folic Acid Reduced Triglycerides Deposition in Primary Chicken Hepatocytes. | 2018 | Details |
| A12371 | 30483536 | JGH Open | Vitamin D supplementation in patients with nonalcoholic fatty liver disease: A randomized controlled trial. | 2017 | Details |
| A12373 | 30482910 | Nat Rev Gastroenterol Hepatol | The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2019 | Details |
| A12378 | 30477827 | Complement Ther Med | The effects of Zataria multiflora Boiss. (Shirazi thyme) on nonalcoholic fatty liver disease and insulin resistance: A randomized double-blind placebo-controlled clinical trial. | 2018 | Details |
| A12379 | 30477455 | BMC Endocr Disord | Treatment with PBI-4050 in patients with Alström syndrome: study protocol for a phase 2, single-Centre, single-arm, open-label trial. | 2018 | Details |
| A12383 | 30474798 | J Endocrinol Invest | Periostin concentrations in childhood-onset craniopharyngioma patients. | 2018 | Details |
| A12384 | 30474288 | Obes Rev | Sarcopenia in patients with non-alcoholic fatty liver disease: is it a clinically significant entity? | 2018 | Details |
| A12390 | 30473057 | Metabolism | Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models. | 2018 | Details |
| A12391 | 30473026 | Life Sci | p53 as a double-edged sword in the progression of non-alcoholic fatty liver disease. | 2018 | Details |
| A12397 | 30472683 | Gut | Alcoholic and non-alcoholic fatty liver disease and associations with coronary artery calcification: evidence from the Kangbuk Samsung Health Study. | 2018 | Details |
| A12401 | 30470912 | Diabetologia | Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus. | 2018 | Details |
| A12403 | 30469392 | J Clin Med | Bidirectional Association between Nonalcoholic Fatty Liver Disease and Gallstone Disease: A Cohort Study. | 2018 | Details |
| A12406 | 30468651 | Front Biosci (Landmark Ed) | Fructose at the crossroads of the metabolic syndrome and obesity epidemics. | 2019 | Details |
| A12407 | 30467936 | Pediatr Diabetes | Non-alcoholic fatty liver disease in pediatric type 2 diabetes: Metabolic and histologic characteristics in 38 subjects. | 2018 | Details |
| A12410 | 30466956 | Clin Nutr | Lean non-alcoholic fatty liver disease. | 2018 | Details |
| A12414 | 30465824 | Free Radic Biol Med | Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia. | 2018 | Details |
| A12421 | 30460863 | Pharm Biol | Mechanism of TangGanJian on nonalcoholic fatty liver disease with type 2 diabetes mellitus. | 2018 | Details |
| A12424 | 30459251 | Diabetes | Targeting Metabolism, Insulin Resistance, and Diabetes to Treat Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12426 | 30458848 | Lipids Health Dis | A longitudinal epidemiological study on the triglyceride and glucose index and the incident nonalcoholic fatty liver disease. | 2018 | Details |
| A12431 | 30457913 | Am J Physiol Endocrinol Metab | Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity. | 2018 | Details |
| A12433 | 30457067 | Proc Nutr Soc | Hepatic fatty acid synthesis and partitioning: the effect of metabolic and nutritional state. | 2018 | Details |
| A12434 | 30456918 | Diabetes Obes Metab | Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis? | 2018 | Details |
| A12435 | 30455723 | Nutr Metab (Lond) | Association of sex hormone-binding globulin with nonalcoholic fatty liver disease in Chinese adults. | 2018 | Details |
| A12440 | 30454891 | Biochem Biophys Res Commun | Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress. | 2018 | Details |
| A12442 | 30454829 | Clin Liver Dis | Will Studies in Nonalcoholic Steatohepatitis Help Manage Alcoholic Steatohepatitis? | 2019 | Details |
| A12444 | 30454678 | Mutat Res Rev Mutat Res | Epigenetics: An emerging field in the pathogenesis of nonalcoholic fatty liver disease. | 2018 | Details |
| A12446 | 30453990 | J Transl Med | Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. | 2018 | Details |
| A12447 | 30453950 | BMC Complement Altern Med | Evaluation of the effect of Lactobacillus reuteri V3401 on biomarkers of inflammation, cardiovascular risk and liver steatosis in obese adults with metabolic syndrome: a randomized clinical trial (PROSIR). | 2018 | Details |
| A12449 | 30453660 | Nutrients | Gut Permeability Might be Improved by Dietary Fiber in Individuals with Nonalcoholic Fatty Liver Disease (NAFLD) Undergoing Weight Reduction. | 2018 | Details |
| A12457 | 30447037 | Diabetes Obes Metab | Effect of canagliflozin treatment on hepatic triglyceride content and glucose metabolism in patients with type 2 diabetes. | 2018 | Details |
| A12458 | 30446932 | Hepatol Int | The effects of curcumin on the metabolic parameters of non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials. | 2018 | Details |
| A12459 | 30446669 | Nat Commun | Serotonin signals through a gut-liver axis to regulate hepatic steatosis. | 2018 | Details |
| A12462 | 30445800 | Cancers (Basel) | Lipid Metabolic Reprogramming in Hepatocellular Carcinoma. | 2018 | Details |
| A12463 | 30445758 | Children (Basel) | Extracellular Vesicles: A Potential Novel Regulator of Obesity and Its Associated Complications. | 2018 | Details |
| A12471 | 30441981 | Vnitr Lek | Future of pharmacological treatment of non-alcoholic steatohepatitis in terms of key pathophysiological mechanisms. | 2019 | Details |
| A12473 | 30431613 | Medicine (Baltimore) | The associations among Helicobacter pylori infection, white blood cell count and nonalcoholic fatty liver disease in a large Chinese population. | 2018 | Details |
| A12474 | 30431378 | Curr Med Res Opin | Severe nonalcoholic steatohepatitis and type 2 diabetes: liver histology after weight loss therapy in a randomized clinical trial. | 2018 | Details |
| A12486 | 30428868 | Lipids Health Dis | Changes in peroxisome proliferator-activated receptor alpha target gene expression in peripheral blood mononuclear cells associated with non-alcoholic fatty liver disease. | 2018 | Details |
| A12487 | 30428692 | Diab Vasc Dis Res | Association of glucagon-to-insulin ratio and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. | 2018 | Details |
| A12492 | 30425763 | J Clin Med Res | Prevalence and Risk Factors of Elevated Liver Enzymes in Japanese Women With Polycystic Ovary Syndrome. | 2018 | Details |
| A12494 | 30425219 | Indian J Med Res | Prevalence, clinical & biochemical correlates of non-alcoholic fatty liver disease in overweight adolescents. | 2018 | Details |
| A12496 | 30422676 | Am J Respir Crit Care Med | Obstructive Sleep Apnea, Hypoxia, and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12499 | 30420265 | Arab J Gastroenterol | Managing diabetes and liver disease association. | 2018 | Details |
| A12502 | 30417996 | Pak J Biol Sci | Comparative Study of Orange and its Main Bioactive Constituents as Remedy for Non-alcoholic Fatty Liver in Rats. | 2018 | Details |
| A12505 | 30415572 | Orv Hetil | [Non-alcoholic fatty liver disease - a summary and update based on the EASL-EASD-EASO Clinical Practice Guidelines of 2016]. | 2018 | Details |
| A12506 | 30415544 | J Agric Food Chem | Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. | 2018 | Details |
| A12512 | 30414175 | J Sci Food Agric | Triticum aestivum ethanolic extract improves non-alcoholic fatty liver disease in mice fed a choline-deficient or high-fat diet. | 2019 | Details |
| A12513 | 30413815 | Lab Invest | Sex-associated preventive effects of low-dose aspirin on obesity and non-alcoholic fatty liver disease in mouse offspring with over-nutrition in utero. | 2018 | Details |
| A12514 | 30413050 | Pharmaceuticals (Basel) | Antidiabetic Drugs in NAFLD: The Accomplishment of Two Goals at Once? | 2018 | Details |
| A12520 | 30411690 | Curr Comput Aided Drug Des | Virtual Screening Strategy Combined Bayesian Classification Model, Molecular Docking for Acetyl-CoA Carboxylases Inhibitors. | 2019 | Details |
| A12522 | 30411515 | Clin Obes | Decreased serum neuregulin 4 levels associated with non-alcoholic fatty liver disease in children with obesity. | 2018 | Details |
| A12527 | 30409703 | Mol Metab | Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis. | 2018 | Details |
| A12530 | 30408433 | Toxicol Appl Pharmacol | 6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction. | 2018 | Details |
| A12533 | 30405551 | Front Microbiol | Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice. | 2018 | Details |
| A12535 | 30404689 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | [Nonalcoholic Fatty Liver Disease and Weight Loss]. | 2018 | Details |
| A12551 | 30394863 | Metab Syndr Relat Disord | Prediction of Insulin Resistance with Anthropometric and Clinical Laboratory Measures in Nondiabetic Teenagers. | 2018 | Details |
| A12554 | 30393477 | Arch Med Sci | Association of non-alcoholic fatty liver disease with cardiovascular disease and subclinical atherosclerosis. | 2017 | Details |
| A12556 | 30392752 | J Hepatol | Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women. | 2018 | Details |
| A12560 | 30391126 | Trends Mol Med | Hypoxia-Inducible Factor Prolyl 4-Hydroxylases and Metabolism. | 2018 | Details |
| A12561 | 30390352 | J Clin Lab Anal | Low serum adiponectin is a predictor of progressing to nonalcoholic fatty liver disease. | 2018 | Details |
| A12565 | 30388763 | Nutrients | Bergamot Polyphenols Boost Therapeutic Effects of the Diet on Non-Alcoholic Steatohepatitis (NASH) Induced by "Junk Food": Evidence for Anti-Inflammatory Activity. | 2018 | Details |
| A12566 | 30388740 | Nutrients | Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism. | 2018 | Details |
| A12567 | 30388378 | Can J Physiol Pharmacol | Histopathological and biochemical changes in the development of nonalcoholic fatty liver disease induced by high-sucrose diet at different times. | 2018 | Details |