Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A17919 | 27477408 | Intern Med | Hyperthyroidism Improves the Pathological Condition of Nonalcoholic Steatohepatitis: A Case of Nonalcoholic Steatohepatitis with Graves' Disease. | 2016 | Details |
| A17927 | 27472963 | Biochim Biophys Acta Mol Cell Biol Lipids | Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis. | 2016 | Details |
| A17932 | 27470139 | Sci Rep | Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice. | 2016 | Details |
| A17935 | 27468220 | World J Gastroenterol | Effectiveness of exercise in hepatic fat mobilization in non-alcoholic fatty liver disease: Systematic review. | 2016 | Details |
| A17936 | 27468193 | World J Gastroenterol | Silybin counteracts lipid excess and oxidative stress in cultured steatotic hepatic cells. | 2016 | Details |
| A17944 | 27459811 | Wei Sheng Yan Jiu | [Change in plasma nesfatin-1 concentration within high-fat diet induced nonalcoholic fatty liver disease rat models]. | 2016 | Details |
| A17952 | 27457618 | Mol Cell Biol | Acetylation of Mitochondrial Trifunctional Protein α-Subunit Enhances Its Stability To Promote Fatty Acid Oxidation and Is Decreased in Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A17958 | 27454769 | PLoS One | Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A17963 | 27447538 | Ann N Y Acad Sci | Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice. | 2016 | Details |
| A17971 | 27445343 | Am J Physiol Gastrointest Liver Physiol | A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. | 2016 | Details |
| A17972 | 27443391 | BMC Med | Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease. | 2016 | Details |
| A17977 | 27439777 | Sci Rep | Caloric restriction of db/db mice reverts hepatic steatosis and body weight with divergent hepatic metabolism. | 2016 | Details |
| A17978 | 27439437 | J Proteome Res | Proteome Dynamics Reveals Pro-Inflammatory Remodeling of Plasma Proteome in a Mouse Model of NAFLD. | 2016 | Details |
| A17981 | 27438262 | PLoS One | Investigating Nonalcoholic Fatty Liver Disease in a Liver-on-a-Chip Microfluidic Device. | 2016 | Details |
| A17994 | 27428872 | Nutr Diabetes | Plasma phospholipids and fatty acid composition differ between liver biopsy-proven nonalcoholic fatty liver disease and healthy subjects. | 2016 | Details |
| A17997 | 27428080 | Lab Invest | Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation. | 2016 | Details |
| A18000 | 27424223 | J Nutr Biochem | Role of lipids in the metabolism and activation of immune cells. | 2015 | Details |
| A18007 | 27421788 | FASEB J | STK25 is a critical determinant in nonalcoholic steatohepatitis. | 2016 | Details |
| A18012 | 27417217 | J Hepatol | Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy. | 2016 | Details |
| A18019 | 27409609 | Int J Mol Sci | Hepatocyte and Sertoli Cell Aquaporins, Recent Advances and Research Trends. | 2016 | Details |
| A18030 | 27404046 | J Gastroenterol Hepatol | Loss of lipopolysaccharide-binding protein attenuates the development of diet-induced non-alcoholic fatty liver disease in mice. | 2017 | Details |
| A18036 | 27393135 | Diabetologia | Effects of exercise training on intrahepatic lipid content in humans. | 2016 | Details |
| A18062 | 27377869 | Clin Exp Immunol | MicroRNA-26a-interleukin (IL)-6-IL-17 axis regulates the development of non-alcoholic fatty liver disease in a murine model. | 2016 | Details |
| A18074 | 27366193 | Evid Based Complement Alternat Med | Untargeted Metabolomics Reveals Intervention Effects of Total Turmeric Extract in a Rat Model of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18082 | 27358174 | Hepatology | Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives. | 2016 | Details |
| A18083 | 27357269 | Mol Med Rep | Impact of activating transcription factor 4 signaling on lipogenesis in HepG2 cells. | 2016 | Details |
| A18091 | 27354540 | Physiol Rep | Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. | 2016 | Details |
| A18105 | 27349145 | Eur J Pharmacol | Effects of the new thiazolidine derivative LPSF/GQ-02 on hepatic lipid metabolism pathways in non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A18113 | 27345365 | Sci Rep | New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats. | 2016 | Details |
| A18115 | 27345267 | Biochim Biophys Acta Mol Basis Dis | Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration. | 2016 | Details |
| A18123 | 27340383 | Immune Netw | The Immune Landscape in Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18131 | 27333187 | PLoS One | Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice. | 2016 | Details |
| A18141 | 27323620 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Effect of Compound Zhajin Granule on Toll-like Receptor 4 Signaling Pathway in Nonalcoholic Steatohepatitis Mice]. | 2016 | Details |
| A18152 | 27318147 | Gastroenterology | Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients. | 2016 | Details |
| A18164 | 27311796 | Food Chem Toxicol | NF-E2-related factor 2 deletion facilitates hepatic fatty acids metabolism disorder induced by high-fat diet via regulating related genes in mice. | 2016 | Details |
| A18174 | 27308945 | Stem Cells Dev | Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha. | 2016 | Details |
| A18194 | 27293995 | Am J Cancer Res | Lack of fibroblast growth factor 21 accelerates metabolic liver injury characterized by steatohepatities in mice. | 2016 | Details |
| A18195 | 27292184 | Biosci Biotechnol Biochem | Protective effect of composite earthworm powder against diabetic complications via increased fibrinolytic function and improvement of lipid metabolism in ZDF rats. | 2016 | Details |
| A18204 | 27288055 | J Endocrinol | Metformin increases hepatic leptin receptor and decreases steatosis in mice. | 2016 | Details |
| A18232 | 27270405 | Lipids | Free Fatty Acids Increase Intracellular Lipid Accumulation and Oxidative Stress by Modulating PPARα and SREBP-1c in L-02 Cells. | 2016 | Details |
| A18234 | 27266874 | BMC Genet | Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12. | 2016 | Details |
| A18235 | 27266339 | J Med Food | Hepatoprotective Effects of Soybean Embryo by Enhancing Adiponectin-Mediated AMP-Activated Protein Kinase α Pathway in High-Fat and High-Cholesterol Diet-Induced Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18247 | 27265384 | Life Sci | Dihydromyricetin ameliorates oleic acid-induced lipid accumulation in L02 and HepG2 cells by inhibiting lipogenesis and oxidative stress. | 2016 | Details |
| A18249 | 27264075 | Mol Cell Endocrinol | Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes. | 2016 | Details |
| A18251 | 27262986 | Environ Toxicol Pharmacol | Impact of high-fat diet on liver genes expression profiles in mice model of nonalcoholic fatty liver disease. | 2016 | Details |
| A18259 | 27260465 | J Nutr Biochem | A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD(+)/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway. | 2016 | Details |
| A18262 | 27257426 | Hepat Mon | Leptin Receptor Gene Polymorphisms and the Risk of Non-Alcoholic Fatty Liver Disease and Coronary Atherosclerosis in the Chinese Han Population. | 2016 | Details |
| A18281 | 27245430 | J Hepatol | Hepatocyte vitamin D receptor regulates lipid metabolism and mediates experimental diet-induced steatosis. | 2016 | Details |
| A18285 | 29879345 | Yao Xue Xue Bao | [Investigating the effects of compound WS090152 on non-alcoholic fatty liver in mice]. | 2016 | Details |
| A18288 | 27239734 | Lab Invest | C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis. | 2016 | Details |
| A18295 | 27234712 | Mol Nutr Food Res | β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes. | 2016 | Details |
| A18296 | 27233614 | Biochem Biophys Res Commun | Spontaneous nonalcoholic fatty liver disease and ER stress in Sidt2 deficiency mice. | 2016 | Details |
| A18298 | 27231906 | Int J Mol Sci | NAFLD and NASH in HCV Infection: Prevalence and Significance in Hepatic and Extrahepatic Manifestations. | 2016 | Details |
| A18299 | 27231887 | Molecules | Ethanolic Extract of Acanthopanax koreanum Nakai Alleviates Alcoholic Liver Damage Combined with a High-Fat Diet in C57BL/6J Mice. | 2016 | Details |
| A18305 | 27225852 | J Hum Genet | MicroRNAs and liver disease. | 2016 | Details |
| A18307 | 27222533 | Gut | Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption. | 2016 | Details |
| A18326 | 27208776 | Biochem Biophys Res Commun | GLP-1 analogue improves hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway. | 2016 | Details |
| A18327 | 27207512 | Diabetes | Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes. | 2016 | Details |
| A18341 | 27196572 | Gut | Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism. | 2016 | Details |
| A18346 | 27189962 | J Pharmacol Exp Ther | Nuclear Factor Erythroid 2-Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen. | 2016 | Details |
| A18353 | 27185526 | Elife | Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis. | 2016 | Details |
| A18357 | 27184670 | BMC Complement Altern Med | Rhodiola crenulata extract regulates hepatic glycogen and lipid metabolism via activation of the AMPK pathway. | 2016 | Details |
| A18369 | 27178550 | Anal Bioanal Chem | High-throughput and rapid quantification of lipids by nanoflow UPLC-ESI-MS/MS: application to the hepatic lipids of rabbits with nonalcoholic fatty liver disease. | 2016 | Details |
| A18372 | 27176782 | Mol Med Rep | Treatment with estrogen protects against ovariectomy-induced hepatic steatosis by increasing AQP7 expression. | 2016 | Details |
| A18377 | 27174168 | Life Sci | Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes. | 2016 | Details |
| A18393 | 27164963 | Chin J Integr Med | Protective Effects of Chaihu Shugan San () on Nonalcoholic Fatty Liver Disease in Rats with Insulin Resistance. | 2016 | Details |
| A18399 | 27158393 | Am J Transl Res | Silymarin attenuated hepatic steatosis through regulation of lipid metabolism and oxidative stress in a mouse model of nonalcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A18402 | 27155918 | J Nutr Biochem | Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice. | 2016 | Details |
| A18406 | 27152979 | J Med Food | Water Extract of Dolichos lablab Attenuates Hepatic Lipid Accumulation in a Cellular Nonalcoholic Fatty Liver Disease Model. | 2016 | Details |
| A18408 | 27153234 | Chemosphere | Metabolic and immune impairments induced by the endocrine disruptors benzo[a]pyrene and triclosan in Xenopus tropicalis. | 2016 | Details |
| A18417 | 27148532 | Front Cell Dev Biol | Roles of FGFs As Paracrine or Endocrine Signals in Liver Development, Health, and Disease. | 2016 | Details |
| A18420 | 27146015 | Annu Rev Nutr | Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis. | 2016 | Details |
| A18423 | 27145114 | Mol Nutr Food Res | Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obese mice. | 2016 | Details |
| A18424 | 27145007 | Endocrinology | Maternal Hyperleptinemia Improves Offspring Insulin Sensitivity in Mice. | 2016 | Details |
| A18431 | 27142736 | J Nutr Biochem | Fucoidan alleviates high-fat diet-induced dyslipidemia and atherosclerosis in ApoE(shl) mice deficient in apolipoprotein E expression. | 2016 | Details |
| A18443 | 30133212 | Zhong Yao Cai | [Protection of Fufang Zhenzhu Tiaozhi Formula on NAFLD in Mice by Regulating ERS]. | 2016 | Details |
| A18447 | 28891620 | Zhongguo Zhong Yao Za Zhi | [Experimental study of Tangshen formulain improved lipid metabolism and phenotypic switch of macrophage in db/db mice]. | 2016 | Details |
| A18449 | 27128907 | Int J Mol Sci | PNPLA3 Expression Is Related to Liver Steatosis in Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A18451 | 27126072 | Biochimie | Hepatosteatosis and estrogen increase apolipoprotein O production in the chicken. | 2016 | Details |
| A18452 | 27125895 | AAPS J | Dual Outcomes of Rosiglitazone Treatment on Fatty Liver. | 2016 | Details |
| A18453 | 27124954 | Genome Med | Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet. | 2016 | Details |
| A18463 | 27111464 | J Appl Microbiol | Gut microbiota-associated bile acid deconjugation accelerates hepatic steatosis in ob/ob mice. | 2016 | Details |
| A18464 | 27110380 | BMJ Open Gastroenterol | Statins, antidiabetic medications and liver histology in patients with diabetes with non-alcoholic fatty liver disease. | 2016 | Details |
| A18467 | 27109475 | Biochem Biophys Res Commun | AMPKα1 overexpression alleviates the hepatocyte model of nonalcoholic fatty liver disease via inactivating p38MAPK pathway. | 2016 | Details |
| A18469 | 27109162 | Am J Chin Med | Rheum palmatum L. Attenuates High Fat Diet-Induced Hepatosteatosis by Activating AMP-Activated Protein Kinase. | 2016 | Details |
| A18471 | 27107702 | Biochem Biophys Res Commun | MicroRNA-421 induces hepatic mitochondrial dysfunction in non-alcoholic fatty liver disease mice by inhibiting sirtuin 3. | 2016 | Details |
| A18474 | 27105497 | Oncotarget | Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes. | 2016 | Details |
| A18484 | 27101131 | Diabetologia | Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions. | 2016 | Details |
| A18487 | 27099265 | Eur Heart J | Liver microRNAs: potential mediators and biomarkers for metabolic and cardiovascular disease? | 2016 | Details |
| A18491 | 27095767 | Zhonghua Gan Zang Bing Za Zhi | [Effect of chitooligosaccharide on hepatic triglyceride metabolism and related mechanisms]. | 2016 | Details |
| A18495 | 27091156 | Cell Mol Life Sci | Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease. | 2016 | Details |
| A18498 | 27090939 | Biochim Biophys Acta | Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. | 2016 | Details |
| A18507 | 27085779 | Metabolism | Computerized tomography measured liver fat is associated with low levels of N-terminal pro-brain natriuretic protein (NT-proBNP). Multi-Ethnic Study of Atherosclerosis. | 2016 | Details |
| A18513 | 27079922 | Sci Rep | Comparisons of parallel potential biomarkers of 1H-MRS-measured hepatic lipid content in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A18520 | 27075663 | BMC Pharmacol Toxicol | Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats. | 2016 | Details |
| A18525 | 27069915 | Biomed Res Int | A Recipe Composed of Chinese Herbal Active Components Regulates Hepatic Lipid Metabolism of NAFLD In Vivo and In Vitro. | 2016 | Details |
| A18526 | 27069901 | Prev Nutr Food Sci | Ameliorative Effects of Pomegranate Peel Extract against Dietary-Induced Nonalcoholic Fatty Liver in Rats. | 2016 | Details |
| A18527 | 27069868 | Mol Metab | Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis. | 2016 | Details |
| A18533 | 27063959 | Transl Res | Interleukin-18-deficient mice develop dyslipidemia resulting in nonalcoholic fatty liver disease and steatohepatitis. | 2016 | Details |
| A18548 | 27063265 | Clin Liver Dis | The Prevalence and Pathobiology of Nonalcoholic Fatty Liver Disease in Patients of Different Races or Ethnicities. | 2016 | Details |