Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19321 | 26630290 | PLoS One | Euterpe oleracea Mart.-Derived Polyphenols Protect Mice from Diet-Induced Obesity and Fatty Liver by Regulating Hepatic Lipogenesis and Cholesterol Excretion. | 2015 | Details |
| A19340 | 26620317 | Sci Rep | Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease. | 2015 | Details |
| A19352 | 26612838 | Toxicol Sci | Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis. | 2015 | Details |
| A19356 | 26609894 | Expert Opin Ther Targets | Pathophysiological mechanisms and therapeutic potentials of macrophages in non-alcoholic steatohepatitis. | 2016 | Details |
| A19362 | 26605757 | Hepatology | The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage. | 2016 | Details |
| A19365 | 26602919 | Int J Mol Sci | Does Lysosomial Acid Lipase Reduction Play a Role in Adult Non-Alcoholic Fatty Liver Disease? | 2015 | Details |
| A19382 | 26598837 | J Nutr Sci Vitaminol (Tokyo) | Lipid Nutrition and Healthy Aging. | 2015 | Details |
| A19383 | 26597784 | Biochim Biophys Acta | Vitamin A deficiency suppresses high fructose-induced triglyceride synthesis and elevates resolvin D1 levels. | 2015 | Details |
| A19385 | 26597602 | J Diabetes Complications | Chronic fructose intake accelerates non-alcoholic fatty liver disease in the presence of essential hypertension. | 2015 | Details |
| A19407 | 26586306 | J Matern Fetal Neonatal Med | Fish oil improves lipid profile in juvenile rats with intrauterine growth retardation by altering the transcriptional expression of lipid-related hepatic genes. | 2015 | Details |
| A19411 | 26583037 | Nutr Metab (Lond) | High fat plus high cholesterol diet lead to hepatic steatosis in zebrafish larvae: a novel model for screening anti-hepatic steatosis drugs. | 2015 | Details |
| A19419 | 26579441 | Acta Pharm Sin B | Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism. | 2015 | Details |
| A19433 | 26571089 | J Ethnopharmacol | Li-Gan-Shi-Liu-Ba-Wei-San improves non-alcoholic fatty liver disease through enhancing lipid oxidation and alleviating oxidation stress. | 2015 | Details |
| A19437 | 26569269 | Mar Drugs | Polyphenol-Rich Fraction of Ecklonia cava Improves Nonalcoholic Fatty Liver Disease in High Fat Diet-Fed Mice. | 2015 | Details |
| A19463 | 26555669 | Mol Nutr Food Res | Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland. | 2015 | Details |
| A19497 | 26522240 | Sci Rep | Cholesterol induces lipoprotein lipase expression in a tree shrew (Tupaia belangeri chinensis) model of non-alcoholic fatty liver disease. | 2015 | Details |
| A19499 | 26519296 | BMC Gastroenterol | Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown-Norway rats. | 2015 | Details |
| A19504 | 26517927 | Biochem Soc Trans | Tribbles-1: a novel regulator of hepatic lipid metabolism in humans. | 2015 | Details |
| A19505 | 26517924 | Biochem Soc Trans | The role of TRIB1 in lipid metabolism; from genetics to pathways. | 2015 | Details |
| A19506 | 29083841 | Acta Med Croatica | [NON-ALCOHOLIC FATTY LIVER DISEASE]. | 2015 | Details |
| A19509 | 26515554 | Exp Cell Res | Pathophysiology of lipid droplet proteins in liver diseases. | 2015 | Details |
| A19526 | 26509584 | Appl Physiol Nutr Metab | Aerobic interval exercise improves parameters of nonalcoholic fatty liver disease (NAFLD) and other alterations of metabolic syndrome in obese Zucker rats. | 2015 | Details |
| A19551 | 26494024 | Nutr Res Rev | Murine models provide insight to the development of non-alcoholic fatty liver disease. | 2015 | Details |
| A19560 | 26485614 | Endocrinology | The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice. | 2015 | Details |
| A19562 | 26485433 | PLoS One | 3,5 Diiodo-L-Thyronine (T2) Does Not Prevent Hepatic Steatosis or Insulin Resistance in Fat-Fed Sprague Dawley Rats. | 2015 | Details |
| A19571 | 26476698 | Clin Res Hepatol Gastroenterol | Lipid deposition in liver cells: The influence of short form augmenter of liver regeneration. | 2015 | Details |
| A19572 | 26476631 | Eur J Nutr | A possible link between hepatic mitochondrial dysfunction and diet-induced insulin resistance. | 2016 | Details |
| A19579 | 26473919 | Nutrients | Optimized Rapeseed Oils Rich in Endogenous Micronutrients Protect High Fat Diet Fed Rats from Hepatic Lipid Accumulation and Oxidative Stress. | 2015 | Details |
| A19595 | 26464382 | J Mol Endocrinol | Glucose fluctuation increased hepatocyte apoptosis under lipotoxicity and the involvement of mitochondrial permeability transition opening. | 2015 | Details |
| A19598 | 26463593 | Genes Nutr | Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice. | 2015 | Details |
| A19599 | 26463349 | Crit Rev Clin Lab Sci | Omega-3 fatty acids: Mechanisms of benefit and therapeutic effects in pediatric and adult NAFLD. | 2015 | Details |
| A19603 | 26462272 | BMJ Open Gastroenterol | Systematic review of genetic association studies involving histologically confirmed non-alcoholic fatty liver disease. | 2015 | Details |
| A19622 | 26450277 | Br J Nutr | Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). | 2015 | Details |
| A19625 | 26449539 | BMC Genomics | The impact of PPARα activation on whole genome gene expression in human precision cut liver slices. | 2015 | Details |
| A19647 | 26438694 | Dis Model Mech | Treatment with a novel oleic-acid-dihydroxyamphetamine conjugation ameliorates non-alcoholic fatty liver disease in obese Zucker rats. | 2015 | Details |
| A19648 | 26438057 | Biometals | Core domain mutant Y220C of p53 protein has a key role in copper homeostasis in case of free fatty acids overload. | 2015 | Details |
| A19662 | 26429665 | Nutrition | ω-3 Fatty acids reverse lipotoxity through induction of autophagy in nonalcoholic fatty liver disease. | 2015 | Details |
| A19672 | 26423094 | J Endocrinol | Hepatic lipase deficiency produces glucose intolerance, inflammation and hepatic steatosis. | 2015 | Details |
| A19673 | 26420354 | Eur J Pharmacol | Deficiency in apolipoprotein A-I ablates the pharmacological effects of metformin on plasma glucose homeostasis and hepatic lipid deposition. | 2015 | Details |
| A19675 | 26419929 | Mol Cell Endocrinol | C1q/TNF-Related Protein 9 (CTRP9) attenuates hepatic steatosis via the autophagy-mediated inhibition of endoplasmic reticulum stress. | 2015 | Details |
| A19683 | 26414963 | J Clin Endocrinol Metab | Sex-Specific Differences in Hepatic Fat Oxidation and Synthesis May Explain the Higher Propensity for NAFLD in Men. | 2015 | Details |
| A19687 | 26409295 | Metabolism | Genetics of nonalcoholic fatty liver disease. | 2015 | Details |
| A19696 | 26405765 | PLoS One | Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil. | 2015 | Details |
| A19702 | 26404765 | Hepatology | Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice. | 2015 | Details |
| A19708 | 26401075 | World J Gastroenterol | Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. | 2015 | Details |
| A19717 | 26397061 | Mol Med Rep | Therapeutic effects of the dipeptidyl peptidase-IV inhibitor, sitagliptin, on non-alcoholic steatohepatitis in FLS-ob/ob male mice. | 2015 | Details |
| A19727 | 26394161 | J Hepatol | Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis. | 2015 | Details |
| A19751 | 26378642 | Semin Liver Dis | Fatty Acid and Glucose Sensors in Hepatic Lipid Metabolism: Implications in NAFLD. | 2015 | Details |
| A19752 | 26378641 | Semin Liver Dis | Systemic Complications of Nonalcoholic Fatty Liver Disease: When the Liver Is Not an Innocent Bystander. | 2015 | Details |
| A19757 | 26377647 | Toxicol Sci | 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice. | 2015 | Details |
| A19758 | 26375281 | PLoS One | Co-Administration of Cholesterol-Lowering Probiotics and Anthraquinone from Cassia obtusifolia L. Ameliorate Non-Alcoholic Fatty Liver. | 2015 | Details |
| A19769 | 26363221 | Mol Cell Endocrinol | AMPK-dependent modulation of hepatic lipid metabolism by nesfatin-1. | 2015 | Details |
| A19773 | 26359013 | Zhonghua Nei Ke Za Zhi | [An epidemiologic study of the relation between non-alcoholic fatty liver disease and glycosylated hemoglobin among middle-aged and aged people]. | 2015 | Details |
| A19774 | 26358367 | Sci Rep | Hyperinsulinemia shifted energy supply from glucose to ketone bodies in early nonalcoholic steatohepatitis from high-fat high-sucrose diet induced Bama minipigs. | 2015 | Details |
| A19797 | 26343136 | Drug Metab Lett | Alterations in Hepatic Lipid Metabolism, and their Relation to Dietary Macronutrients in Pediatric Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19805 | 26339640 | Biomed Res Int | The Role of Dendritic Cells in Fibrosis Progression in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19807 | 26338827 | Gut | Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression. | 2015 | Details |
| A19811 | 26335364 | Biochem Cell Biol | Lactoferrin attenuates fatty acid-induced lipotoxicity via Akt signaling in hepatocarcinoma cells. | 2015 | Details |
| A19814 | 26330688 | Trans Am Clin Climatol Assoc | A Lipidomic Readout of Disease Progression in A Diet-Induced Mouse Model of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19816 | 26330104 | Sci Rep | Effect of miR-34a in regulating steatosis by targeting PPARα expression in nonalcoholic fatty liver disease. | 2015 | Details |
| A19826 | 26323153 | Zhongguo Zhong Yao Za Zhi | [Experimental study on intervention effect of Grifola frondosa on nonalcoholic steatohepatitis]. | 2015 | Details |
| A19838 | 26315841 | Int J Obes (Lond) | Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. | 2015 | Details |
| A19848 | 26310987 | Int J Cardiol | Mechanistic link between nonalcoholic fatty liver disease and cardiometabolic disorders. | 2015 | Details |
| A19849 | 28943619 | Diseases | MOGAT2: A New Therapeutic Target for Metabolic Syndrome. | 2015 | Details |
| A19854 | 26303333 | Toxicology | Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes. | 2015 | Details |
| A19860 | 26300331 | J Nutr Biochem | Decaffeinated green tea extract rich in epigallocatechin-3-gallate prevents fatty liver disease by increased activities of mitochondrial respiratory chain complexes in diet-induced obesity mice. | 2015 | Details |
| A19872 | 26292849 | Br J Pharmacol | Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes. | 2015 | Details |
| A19881 | 26288848 | EBioMedicine | Reduced Lysosomal Acid Lipase Activity in Adult Patients With Non-alcoholic Fatty Liver Disease. | 2015 | Details |
| A19883 | 26285328 | Vopr Kurortol Fizioter Lech Fiz Kult | [The effectiveness of the spa and health resort-based treatment with the application of Essentuki-type drinking mineral waters for the management of non-alcoholic fatty liver disease in the patients presenting with type 2 diabetes mellitus]. | 2015 | Details |
| A19884 | 26284975 | Biochem Biophys Res Commun | Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity. | 2015 | Details |
| A19888 | 26282675 | Gut | MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway. | 2015 | Details |
| A19910 | 26272872 | J Hepatol | Upregulation of miR-125b by estrogen protects against non-alcoholic fatty liver in female mice. | 2015 | Details |
| A19911 | 26272871 | J Hepatol | Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial. | 2015 | Details |
| A19919 | 26265792 | Clin Sci (Lond) | Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial. | 2015 | Details |
| A19925 | 26262841 | J Agric Food Chem | Mass-Spectrometry-Based Serum Metabolomics of a C57BL/6J Mouse Model of High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease Development. | 2015 | Details |
| A19927 | 26260846 | Biochim Biophys Acta | 14-3-3β and γ differentially regulate peroxisome proliferator activated receptor γ2 transactivation and hepatic lipid metabolism. | 2015 | Details |
| A19942 | 26252777 | PLoS One | Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease. | 2015 | Details |
| A19946 | 26250597 | J Sci Food Agric | Anthocyanin-rich extracts from blackberry, wild blueberry, strawberry, and chokeberry: antioxidant activity and inhibitory effect on oleic acid-induced hepatic steatosis in vitro. | 2015 | Details |
| A19950 | 26246323 | J Nutr | Citrulline and Nonessential Amino Acids Prevent Fructose-Induced Nonalcoholic Fatty Liver Disease in Rats. | 2015 | Details |
| A19953 | 26242978 | Lipids Health Dis | Prevention and treatment effect of total flavonoids in Stellera chamaejasme L. on nonalcoholic fatty liver in rats. | 2015 | Details |
| A19966 | 26235878 | Biochem Biophys Res Commun | The role of endoplasmic reticulum stress and insulin resistance in the occurrence of goose fatty liver. | 2015 | Details |
| A19968 | 26234526 | Br J Nutr | The effects of resveratrol supplementation on cardiovascular risk factors in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study. | 2015 | Details |
| A19972 | 26233687 | Arch Toxicol | RNAi in murine hepatocytes: the agony of choice--a study of the influence of lipid-based transfection reagents on hepatocyte metabolism. | 2015 | Details |
| A19973 | 26232233 | Am J Physiol Heart Circ Physiol | Translational approaches to understanding metabolic dysfunction and cardiovascular consequences of obstructive sleep apnea. | 2015 | Details |
| A19976 | 26229402 | World J Gastroenterol | Linked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B. | 2015 | Details |
| A19987 | 26224399 | Expert Rev Gastroenterol Hepatol | Understanding the association between developing a fatty liver and subsequent cardio-metabolic complications. | 2015 | Details |
| A19996 | 26215699 | J Pharmacol Sci | JTP-103237, a monoacylglycerol acyltransferase inhibitor, prevents fatty liver and suppresses both triglyceride synthesis and de novo lipogenesis. | 2015 | Details |
| A20017 | 26203166 | J Endocrinol | Hepatic insulin resistance and increased hepatic glucose production in mice lacking Fgf21. | 2015 | Details |
| A20019 | 26202539 | Br J Nutr | Efficacy of the Omega-3 Index in predicting non-alcoholic fatty liver disease in overweight and obese adults: a pilot study. | 2015 | Details |
| A20034 | 26198708 | Wiley Interdiscip Rev RNA | 'Micro-managers' of hepatic lipid metabolism and NAFLD. | 2015 | Details |
| A20041 | 26194065 | Cytokine | PPARα/γ agonists and antagonists differently affect hepatic lipid metabolism, oxidative stress and inflammatory cytokine production in steatohepatitic rats. | 2015 | Details |
| A20042 | 26193881 | Lipids Health Dis | Eicosapentaenoic and docosahexaenoic acid-enriched high fat diet delays the development of fatty liver in mice. | 2015 | Details |
| A20050 | 26190559 | Food Funct | Modulation of tissue fatty acids by L-carnitine attenuates metabolic syndrome in diet-induced obese rats. | 2015 | Details |
| A20053 | 26190035 | Hepatol Res | Amelioration of free fatty acid-induced fatty liver by quercetin-3-O-β-D-glucuronide through modulation of peroxisome proliferator-activated receptor-alpha/sterol regulatory element-binding protein-1c signaling. | 2015 | Details |
| A20054 | 26189985 | Clin Res Hepatol Gastroenterol | Synergy between NAFLD and AFLD and potential biomarkers. | 2015 | Details |
| A20056 | 26187937 | JPEN J Parenter Enteral Nutr | Clinically Relevant Mechanisms of Lipid Synthesis, Transport, and Storage. | 2015 | Details |
| A20058 | 26187450 | Toxicol Sci | Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in Mice. | 2015 | Details |
| A20063 | 26185377 | World J Gastroenterol | Ameliorative effects of lutein on non-alcoholic fatty liver disease in rats. | 2015 | Details |
| A20064 | 26183212 | Dis Model Mech | Ovarian senescence increases liver fibrosis in humans and zebrafish with steatosis. | 2015 | Details |
| A20073 | 26174847 | Sleep Breath | Relationship between obstructive sleep apnea and nonalcoholic fatty liver disease in nonobese adults. | 2015 | Details |