Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09782 | 31612634 | Liver Int | Liver fibrosis by FibroScan® independently of established cardiovascular risk parameters associates with macrovascular and microvascular complications in patients with type 2 diabetes. | 2019 | Details |
| A09786 | 31610584 | Z Gastroenterol | A 2-step fast-track elastometry service for advanced workup of nonalcoholic fatty liver disease (NAFLD) patients - single-center real-world experience of outpatient clinical practice. | 2019 | Details |
| A09789 | 31610081 | Liver Transpl | Nonalcoholic Steatohepatitis After Liver Transplantation. | 2019 | Details |
| A09792 | 31609745 | Clin Transl Gastroenterol | Detection of Liver Steatosis With a Novel Ultrasound-Based Technique: A Pilot Study Using MRI-Derived Proton Density Fat Fraction as the Gold Standard. | 2019 | Details |
| A09796 | 31607566 | Dig Liver Dis | L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. | 2019 | Details |
| A09799 | 31605031 | Nat Rev Gastroenterol Hepatol | Adaptive immunity: an emerging player in the progression of NAFLD. | 2019 | Details |
| A09802 | 31604692 | Diabetes Care | Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes. | 2019 | Details |
| A09808 | 31602526 | J Gastroenterol | Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients. | 2019 | Details |
| A09809 | 31602167 | World J Gastroenterol | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history. | 2019 | Details |
| A09811 | 31601229 | Trials | Effect of probiotic supplementation in nonalcoholic steatohepatitis patients: PROBILIVER TRIAL protocol. | 2019 | Details |
| A09813 | 31600834 | Hepatology | qFIBS: An Automated Technique for Quantitative Evaluation of Fibrosis, Inflammation, Ballooning, and Steatosis in Patients With Nonalcoholic Steatohepatitis. | 2020 | Details |
| A09814 | 31600750 | Digestion | Rodent Models of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09818 | 31599067 | Mol Nutr Food Res | Mastiha (Pistacia lentiscus) Improves Gut Microbiota Diversity, Hepatic Steatosis, and Disease Activity in a Biopsy-Confirmed Mouse Model of Advanced Non-Alcoholic Steatohepatitis and Fibrosis. | 2019 | Details |
| A09824 | 31597900 | Nihon Yakurigaku Zasshi | [Mechanisms of hepatic stellate cell activation as a therapeutic target for the treatment of non-alcoholic steatohepatitis]. | 2019 | Details |
| A09827 | 31597406 | Cells | A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A09828 | 31597206 | J Gastroenterol Hepatol | The characteristics and risk factors of hepatocellular carcinoma in nonalcoholic fatty liver disease without cirrhosis. | 2019 | Details |
| A09829 | 31597010 | Liver Transpl | Increased Frequency of Heterozygous Alpha-1-Antitrypsin Deficiency in Liver Explants From Nonalcoholic Steatohepatitis Patients. | 2019 | Details |
| A09830 | 31595673 | EMBO Mol Med | Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis. | 2019 | Details |
| A09833 | 31595260 | Porto Biomed J | Prevalence and risk factors of sonographically detected non alcoholic fatty liver disease in a screening centre in Klang Valley, Malaysia: an observational cross-sectional study. | 2018 | Details |
| A09834 | 31595236 | Porto Biomed J | Dietary cholesterol does not break your heart but kills your liver. | 2019 | Details |
| A09835 | 31595205 | Aging Dis | Pyroptosis in Liver Disease: New Insights into Disease Mechanisms. | 2019 | Details |
| A09841 | 31594008 | Ultraschall Med | Establishing Reliability Criteria for Liver ElastPQ Shear Wave Elastography (ElastPQ-SWE): Comparison Between 10, 5 and 3 Measurements. | 2019 | Details |
| A09844 | 31593012 | Pancreas | The Prevalence of Nonalcoholic Fatty Pancreas by Endoscopic Ultrasonography. | 2019 | Details |
| A09847 | 31592448 | Endocrinol Diabetes Metab | Hepatic steatosis in patients with acromegaly. | 2019 | Details |
| A09849 | 31592044 | Hepatol Commun | Impact of Implementing a "FIB-4 First" Strategy on a Pathway for Patients With NAFLD Referred From Primary Care. | 2019 | Details |
| A09853 | 31591383 | Cell Death Dis | Progranulin attenuates liver fibrosis by downregulating the inflammatory response. | 2019 | Details |
| A09856 | 31590120 | Curr Opin Pharmacol | New and emerging anti-fibrotic therapeutics entering or already in clinical trials in chronic liver diseases. | 2019 | Details |
| A09857 | 31589891 | J Hepatol | Change in hepatic fat content measured by MRI does not predict treatment-induced histological improvement of steatohepatitis. | 2019 | Details |
| A09865 | 31584681 | JAMA Netw Open | Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09867 | 31583739 | Aliment Pharmacol Ther | Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. | 2019 | Details |
| A09876 | 31578240 | Sci Transl Med | Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates. | 2019 | Details |
| A09880 | 31577134 | Anal Chem | Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues. | 2019 | Details |
| A09882 | 31575546 | Cancer Res | HNF4α-Deficient Fatty Liver Provides a Permissive Environment for Sex-Independent Hepatocellular Carcinoma. | 2019 | Details |
| A09883 | 31575467 | Ann Hepatol | Evaluation of thrombocytopenia in patients with non-alcoholic fatty liver disease without cirrhosis. | 2019 | Details |
| A09886 | 31574533 | Carcinogenesis | Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation. | 2020 | Details |
| A09887 | 31574313 | Clin Gastroenterol Hepatol | Performance of Simple Fibrosis Scores in Nonobese Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09894 | 31571145 | Arch Pharm Res | Molecular insights into the role of mitochondria in non-alcoholic fatty liver disease. | 2019 | Details |
| A09908 | 31565874 | Endocrinol Metab (Seoul) | Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective. | 2019 | Details |
| A09910 | 31564568 | Pathol Res Pract | Dietary fat, cholesterol, and cholic acid affect the histopathologic severity of nonalcoholic steatohepatitis in Sprague-Dawley rats. | 2019 | Details |
| A09911 | 31563875 | Gut | Quantifying and monitoring fibrosis in non-alcoholic fatty liver disease using dual-photon microscopy. | 2019 | Details |
| A09912 | 31563650 | Eur J Pharmacol | Therapeutic effect of treatment with metformin and/or 4-hydroxychalcone in male Wistar rats with nonalcoholic fatty liver disease. | 2019 | Details |
| A09913 | 31563624 | Gastroenterology | Ability of Noninvasive Scoring Systems to Identify Individuals in the Population at Risk for Severe Liver Disease. | 2019 | Details |
| A09920 | 31559605 | Hepatol Int | Non-obese histologically confirmed NASH patients with abnormal liver biochemistry have more advanced fibrosis. | 2019 | Details |
| A09922 | 31559105 | World J Gastrointest Pathophysiol | Overview of studies of the vitamin D/vitamin D receptor system in the development of non-alcoholic fatty liver disease. | 2019 | Details |
| A09926 | 31558407 | Surg Obes Relat Dis | Impact of a preoperative low-calorie diet on liver histology in patients with fatty liver disease undergoing bariatric surgery. | 2019 | Details |
| A09928 | 31556124 | Hepatology | Clinical Utility of an Increase in Magnetic Resonance Elastography in Predicting Fibrosis Progression in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A09937 | 31554274 | Int J Environ Res Public Health | Overview of the Pathogenesis, Genetic, and Non-Invasive Clinical, Biochemical, and Scoring Methods in the Assessment of NAFLD. | 2019 | Details |
| A09943 | 31551515 | Cell Mol Immunol | NLRP3 inflammasome blockade reduces adipose tissue inflammation and extracellular matrix remodeling. | 2019 | Details |
| A09945 | 31549590 | Curr HIV Res | Liver Fibrosis Assessment in a Cohort of Greek HIV Mono-Infected Patients by Non-Invasive Biomarkers. | 2019 | Details |
| A09954 | 31543862 | Front Endocrinol (Lausanne) | The Role of Thyroid Hormones in Hepatocyte Proliferation and Liver Cancer. | 2019 | Details |
| A09955 | 31543686 | World J Gastroenterol | Value of controlled attenuation parameter in fibrosis prediction in nonalcoholic steatohepatitis. | 2019 | Details |
| A09956 | 31543682 | World J Gastroenterol | Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source. | 2019 | Details |
| A09961 | 31543356 | Ultrasound Med Biol | Acoustic Radiation Force Impulse and Conventional Ultrasound in the Prediction of Cirrhosis Complicating Fatty Liver: Does Body Mass Index Independently Alter the Results? | 2019 | Details |
| A09967 | 31541591 | J Pineal Res | Melatonin safeguards against fatty liver by antagonizing TRAFs-mediated ASK1 deubiquitination and stabilization in a β-arrestin-1 dependent manner. | 2019 | Details |
| A09970 | 31540081 | Nutrients | Dietary Supplementation with Hazelnut Oil Reduces Serum Hyperlipidemia and Ameliorates the Progression of Nonalcoholic Fatty Liver Disease in Hamsters Fed a High-Cholesterol Diet. | 2019 | Details |
| A09977 | 31538495 | Climacteric | Lack of association between early menopause and non-alcoholic fatty liver disease in postmenopausal women. | 2019 | Details |
| A09979 | 31538241 | J Gastroenterol | Diagnostic accuracy of combined biomarker measurements and vibration-controlled transient elastography (VCTE) for predicting fibrosis stage of non-alcoholic fatty liver disease. | 2019 | Details |
| A09980 | 31538216 | Herz | Cardiac abnormalities in patients with nonalcoholic fatty liver disease : Insights from auxiliary examinations. | 2019 | Details |
| A09983 | 31536725 | Eur J Pharmacol | Farnesoid X nuclear receptor agonists for the treatment of nonalcoholic steatohepatitis. | 2019 | Details |
| A09985 | 31536511 | PLoS One | Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial. | 2019 | Details |
| A09987 | 31535207 | J Gastroenterol | Association between body size-metabolic phenotype and nonalcoholic steatohepatitis and significant fibrosis. | 2019 | Details |
| A09990 | 31534089 | Intern Med | Predictors of Insulin Secretion in Japanese Patients with Histopathologically-confirmed Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09998 | 31531097 | Iran J Pathol | The Correlation between Serum Zinc Level and Liver Histology in Non-Alcoholic Steatohepatitis. | 2018 | Details |
| A10000 | 31530739 | Gut Liver | Simple Noninvasive Scores Are Clinically Useful to Exclude, Not Predict, Advanced Fibrosis: A Study in Turkish Patients with Biopsy-Proven Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A10001 | 31530714 | Gut | Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells. | 2019 | Details |
| A10004 | 31529394 | Obes Surg | Non-Alcoholic Fatty Liver Disease Is Associated with Impairment of Ejection Fraction Among Individuals with Obesity Undergoing Bariatric Surgery: Results of a Cross-Sectional Study. | 2020 | Details |
| A10006 | 31528245 | World J Hepatol | Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice. | 2019 | Details |
| A10012 | 31524771 | Eur J Gastroenterol Hepatol | The interaction between current smoking and hemoglobin on the risk of advanced fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease. | 2020 | Details |
| A10013 | 31524533 | Expert Opin Investig Drugs | Multi-drug approaches to NASH: what's in the development pipeline? | 2019 | Details |
| A10014 | 31523999 | Expert Opin Investig Drugs | Elafibranor: a potential drug for the treatment of nonalcoholic steatohepatitis (NASH). | 2019 | Details |
| A10015 | 31523515 | PeerJ | Nicotinamide riboside exerts protective effect against aging-induced NAFLD-like hepatic dysfunction in mice. | 2019 | Details |
| A10019 | 31523414 | Ther Adv Chronic Dis | n-3 PUFAs reduce tumor load and improve survival in a NASH-tumor mouse model. | 2019 | Details |
| A10031 | 31519114 | Expert Opin Investig Drugs | GS-0976 (Firsocostat): an investigational liver-directed acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH). | 2019 | Details |
| A10037 | 31517638 | Am J Gastroenterol | Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels. | 2019 | Details |
| A10038 | 31517325 | J Gastrointestin Liver Dis | Step layered combination of noninvasive fibrosis models improves diagnostic accuracy of advanced fibrosis in nonalcoholic fatty liver disease. | 2019 | Details |
| A10040 | 31517316 | J Gastrointestin Liver Dis | Combination of non-invasive fibrosis tests: a solution for the prediction of advanced fibrosis in non-alcoholic fatty liver disease? | 2019 | Details |
| A10041 | 31516268 | J Clin Exp Hepatol | Drug Development for Nonalcoholic Fatty Liver Disease: Landscape and Challenges. | 2019 | Details |
| A10043 | 31516266 | J Clin Exp Hepatol | Magnitude of Nonalcoholic Fatty Liver Disease: Western Perspective. | 2019 | Details |
| A10044 | 31516265 | J Clin Exp Hepatol | Magnitude of Nonalcoholic Fatty Liver Disease: Eastern Perspective. | 2019 | Details |
| A10052 | 31512278 | J Gastroenterol Hepatol | Non-alcoholic fatty liver disease and the incidence of myocardial infarction: A cohort study. | 2019 | Details |
| A10053 | 31510105 | Cells | New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease. | 2019 | Details |
| A10057 | 31506634 | Lab Invest | Automated computerized image analysis for the user-independent evaluation of disease severity in preclinical models of NAFLD/NASH. | 2019 | Details |
| A10063 | 31505325 | Redox Biol | Peroxiredoxin 5 ameliorates obesity-induced non-alcoholic fatty liver disease through the regulation of oxidative stress and AMP-activated protein kinase signaling. | 2019 | Details |
| A10064 | 31505261 | Biochim Biophys Acta Mol Cell Biol Lipids | Lipid accumulation impairs lysosomal acid lipase activity in hepatocytes: Evidence in NAFLD patients and cell cultures. | 2019 | Details |
| A10065 | 31505040 | Hepatology | Hepatocyte Stress Increases Expression of Yes-Associated Protein and Transcriptional Coactivator With PDZ-Binding Motif in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis. | 2020 | Details |
| A10067 | 31504710 | J Nutr | Food Insecurity May Be an Independent Risk Factor Associated with Nonalcoholic Fatty Liver Disease among Low-Income Adults in the United States. | 2020 | Details |
| A10071 | 31503268 | Food Funct | Green tea extract inhibits early oncogenic responses in mice with nonalcoholic steatohepatitis. | 2019 | Details |
| A10087 | 31493247 | Hormones (Athens) | Selenium and selenoprotein P in nonalcoholic fatty liver disease. | 2019 | Details |
| A10097 | 31485568 | Mayo Clin Proc Innov Qual Outcomes | A Practical Guideline for Hepatocellular Carcinoma Screening in Patients at Risk. | 2019 | Details |
| A10113 | 31478458 | Mol Imaging | PET/SPECT Molecular Probes for the Diagnosis and Staging of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A10122 | 31474685 | J Nutr Sci Vitaminol (Tokyo) | Age-Related Alterations of Nonalcoholic Steatohepatitis in Sprague-Dawley Rats Fed a High-Fat and High-Cholesterol Diet. | 2019 | Details |
| A10124 | 31474633 | Yakugaku Zasshi | [Involvement of the Free Fatty Acid Receptor GPR120/FFAR4 in the Development of Nonalcoholic Steatohepatitis]. | 2019 | Details |
| A10126 | 31474631 | Yakugaku Zasshi | [Inhibition of Group IVA Phospholipase A2 as a Novel Therapeutic Strategy for Nonalcoholic Steatohepatitis]. | 2019 | Details |
| A10130 | 31473746 | Dig Dis | Increased Prevalence of Colorectal Adenomas in Patients with Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study. | 2019 | Details |
| A10136 | 31471434 | BMJ Open | The association between a non-invasive hepatic fibrosis score and urolithiasis among non-alcoholic fatty liver disease (NAFLD) patients in China: a cross-sectional study. | 2019 | Details |
| A10140 | 31470644 | Cells | The miRFIB-Score: A Serological miRNA-Based Scoring Algorithm for the Diagnosis of Significant Liver Fibrosis. | 2019 | Details |
| A10141 | 31470620 | Molecules | Study of Methionine Choline Deficient Diet-Induced Steatosis in Mice Using Endogenous Fluorescence Spectroscopy. | 2019 | Details |
| A10143 | 31470414 | Endocr Connect | Insulin resistance associates with hepatic lobular inflammation in subjects with obesity. | 2019 | Details |
| A10147 | 31470067 | J Hepatol | Transient elastography for screening of liver fibrosis: Cost-effectiveness analysis from six prospective cohorts in Europe and Asia. | 2019 | Details |
| A10148 | 31469911 | Hepatology | hnRNPU/TrkB Defines a Chromatin Accessibility Checkpoint for Liver Injury and Nonalcoholic Steatohepatitis Pathogenesis. | 2020 | Details |