Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A18474 | 27105497 | Oncotarget | Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes. | 2016 | Details |
| A18488 | 27096691 | J Pharm Pharm Sci | Non-Alcoholic Steatohepatitis: Clinical and Translational Research. | 2016 | Details |
| A18501 | 27089331 | Int J Mol Sci | NAFLD and Chronic Kidney Disease. | 2016 | Details |
| A18509 | 27085070 | Biochim Biophys Acta | Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease. | 2016 | Details |
| A18511 | 27083404 | Obes Res Clin Pract | Body mass index and the visceral adipose tissue expression of IL-6 and TNF-alpha are associated with the morphological severity of non-alcoholic fatty liver disease in individuals with class III obesity. | 2016 | Details |
| A18520 | 27075663 | BMC Pharmacol Toxicol | Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats. | 2016 | Details |
| A18523 | 27073470 | Exp Ther Med | Low simvastatin concentrations reduce oleic acid-induced steatosis in HepG2 cells: An in vitro model of non-alcoholic fatty liver disease. | 2016 | Details |
| A18538 | 27063275 | Clin Liver Dis | Emerging Therapies for Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18539 | 27063274 | Clin Liver Dis | Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18559 | 27057275 | Oxid Med Cell Longev | Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis. | 2016 | Details |
| A18580 | 27049024 | J Lipid Res | Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis. | 2016 | Details |
| A18583 | 27046953 | Yonago Acta Med | Components of Boiogito Suppress the Progression of Hypercholesterolemia and Fatty Liver Induced by High-Cholesterol Diet in Rats. | 2016 | Details |
| A18608 | 27037502 | Int J Exp Pathol | Pathological characterization and morphometric analysis of hepatic lesions in SHRSP5/Dmcr, an experimental non-alcoholic steatohepatitis model, induced by high-fat and high-cholesterol diet. | 2016 | Details |
| A18631 | 27023537 | Int J Mol Sci | Additive Effect of Non-Alcoholic Fatty Liver Disease on Metabolic Syndrome-Related Endothelial Dysfunction in Hypertensive Patients. | 2016 | Details |
| A18642 | 27018382 | Biochem Biophys Res Commun | Protective effects of Lactobacillus rhamnosus GG against dyslipidemia in high-fat diet-induced obese mice. | 2016 | Details |
| A18643 | 27018279 | Geriatr Gerontol Int | Involvement of senescence marker protein-30 in glucose metabolism disorder and non-alcoholic fatty liver disease. | 2016 | Details |
| A18648 | 27016281 | J Hepatol | DKK3 expression in hepatocytes defines susceptibility to liver steatosis and obesity. | 2016 | Details |
| A18652 | 27014655 | Adv Biomed Res | Relationship between non-alcoholic fatty liver disease and inflammation in patients with non-alcoholic fatty liver. | 2016 | Details |
| A18654 | 27012627 | J Nutr Biochem | Hydroxytyrosol prevents metabolic impairment reducing hepatic inflammation and restoring duodenal integrity in a rat model of NAFLD. | 2016 | Details |
| A18655 | 27012620 | J Nutr Biochem | Electronegative LDL is linked to high-fat, high-cholesterol diet-induced nonalcoholic steatohepatitis in hamsters. | 2015 | Details |
| A18663 | 27005704 | Sci Rep | Prohibitin-induced, obesity-associated insulin resistance and accompanying low-grade inflammation causes NASH and HCC. | 2016 | Details |
| A18673 | 27002799 | Am J Gastroenterol | Vitamin D Deficiency Is Associated With Increased Risk of Non-alcoholic Steatohepatitis in Adults With Non-alcoholic Fatty Liver Disease: Possible Role for MAPK and NF-κB? | 2016 | Details |
| A18680 | 27001282 | Nutr Res | Opuntia ficus-indica seed attenuates hepatic steatosis and promotes M2 macrophage polarization in high-fat diet-fed mice. | 2015 | Details |
| A18693 | 26997011 | Indian J Med Res | Role of γ-glutamyl transferase levels in prediction of high cardiovascular risk among patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A18725 | 26981209 | World J Cardiol | Psoriasis, non-alcoholic fatty liver disease, and cardiovascular disease: Three different diseases on a unique background. | 2016 | Details |
| A18747 | 26972505 | J Ethnopharmacol | Schisandra chinensis extract ameliorates nonalcoholic fatty liver via inhibition of endoplasmic reticulum stress. | 2016 | Details |
| A18752 | 26971824 | Gastroenterology | Perspectives on Treatment for Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18755 | 26970305 | Biochem Biophys Res Commun | Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress. | 2016 | Details |
| A18758 | 26968211 | Am J Physiol Gastrointest Liver Physiol | Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis. | 2016 | Details |
| A18761 | 26962056 | Toxicol Sci | Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice. | 2016 | Details |
| A18784 | 26944023 | Contemp Clin Trials | Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design. | 2016 | Details |
| A18786 | 26942201 | Biomed Res Int | Advanced Glycation End Products Induce Obesity and Hepatosteatosis in CD-1 Wild-Type Mice. | 2016 | Details |
| A18793 | 26937137 | World J Gastroenterol | Hepatocellular carcinoma and non-alcoholic steatohepatitis: The state of play. | 2016 | Details |
| A18795 | 26936230 | Sci Rep | Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice with Diet-induced Obesity. | 2016 | Details |
| A18805 | 26930651 | PLoS One | Metformin Changes the Relationship between Blood Monocyte Toll-Like Receptor 4 Levels and Nonalcoholic Fatty Liver Disease-Ex Vivo Studies. | 2016 | Details |
| A18807 | 26928243 | Gastroenterology | Pathogenesis of Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18820 | 26921863 | J Affect Disord | Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice. | 2016 | Details |
| A18828 | 26915720 | Gen Physiol Biophys | Hepatoprotective potential of zingerone against nonalcoholic fatty liver disease in rats fed with fructose-enriched diet. | 2016 | Details |
| A18834 | 26911834 | Sci Rep | Resveratrol ameliorates fibrosis and inflammation in a mouse model of nonalcoholic steatohepatitis. | 2016 | Details |
| A18843 | 26907206 | Metabolism | Nonalcoholic fatty liver disease and hepatocellular carcinoma. | 2016 | Details |
| A18844 | 26906544 | Biochim Biophys Acta | PXR- and CAR-mediated herbal effect on human diseases. | 2016 | Details |
| A18852 | 26901500 | PLoS One | Characterization of Liver Monocytic Myeloid-Derived Suppressor Cells and Their Role in a Murine Model of Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A18853 | 26901384 | Liver Int | Deregulated hepatic microRNAs underlie the association between non-alcoholic fatty liver disease and coronary artery disease. | 2016 | Details |
| A18856 | 26900108 | J Agric Food Chem | Ginger Essential Oil Ameliorates Hepatic Injury and Lipid Accumulation in High Fat Diet-Induced Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18863 | 26895034 | PLoS One | Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis. | 2016 | Details |
| A18865 | 26894897 | Cell Mol Life Sci | Pathogenesis of nonalcoholic steatohepatitis. | 2016 | Details |
| A18875 | 26890135 | Cell Death Dis | Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease. | 2016 | Details |
| A18890 | 26882989 | Nat Commun | Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. | 2016 | Details |
| A18894 | 26881444 | Curr Pharm Des | Interrelationship Between Periapical Lesion and Systemic Metabolic Disorders. | 2016 | Details |
| A18919 | 26870934 | Semin Liver Dis | Nuclear Receptor Modulation for the Treatment of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18920 | 26870930 | Semin Liver Dis | Targeting Cell Death and Sterile Inflammation Loop for the Treatment of Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18933 | 26861390 | Nutrients | Psoralea corylifolia L. Seed Extract Attenuates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced Obese Mice. | 2016 | Details |
| A18936 | 26860405 | J Hepatol | Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis. | 2016 | Details |
| A18940 | 26858440 | Proc Natl Acad Sci U S A | Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease. | 2016 | Details |
| A18950 | 26855179 | Biochim Biophys Acta | Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity. | 2016 | Details |
| A18954 | 26852185 | Br J Clin Pharmacol | The role of nutraceuticals for the treatment of non-alcoholic fatty liver disease. | 2016 | Details |
| A18961 | 26847547 | Rev Endocr Metab Disord | The role of immune cells in metabolism-related liver inflammation and development of non-alcoholic steatohepatitis (NASH). | 2016 | Details |
| A18971 | 26843485 | EMBO J | p38γ and p38δ reprogram liver metabolism by modulating neutrophil infiltration. | 2016 | Details |
| A18972 | 26842974 | J Chin Med Assoc | Lipid-lowering, hepatoprotective, and atheroprotective effects of the mixture Hong-Qu and gypenosides in hyperlipidemia with NAFLD rats. | 2016 | Details |
| A18973 | 26841783 | Dig Dis Sci | Innate Immunity and Inflammation in NAFLD/NASH. | 2016 | Details |
| A18977 | 26838182 | Food Funct | Anti-steatotic and anti-inflammatory roles of syringic acid in high-fat diet-induced obese mice. | 2016 | Details |
| A18983 | 26832365 | Lipids Health Dis | Fish oil alleviated high-fat diet-induced non-alcoholic fatty liver disease via regulating hepatic lipids metabolism and metaflammation: a transcriptomic study. | 2016 | Details |
| A18995 | 28871698 | Zhongguo Zhong Yao Za Zhi | [Effect of total flavones of hawthorn leafonon expression of COX-2/Nrf2 in liver of rats with nonalcoholic steatohepatitis]. | 2016 | Details |
| A18996 | 28868866 | Zhongguo Zhong Yao Za Zhi | [Mechanism of geniposide in improving free fatty acid metabolism in rats with non-alcoholic fatty liver disease]. | 2016 | Details |
| A19007 | 26822232 | Hepatology | Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes. | 2016 | Details |
| A19036 | 26808498 | J Clin Invest | Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9. | 2016 | Details |
| A19052 | 26799523 | J Food Sci | Effects of Long-Chain and Medium-Chain Fatty Acids on Apoptosis and Oxidative Stress in Human Liver Cells with Steatosis. | 2016 | Details |
| A19057 | 26794269 | Nat Rev Drug Discov | Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies. | 2016 | Details |
| A19058 | 26794005 | J Gastroenterol | Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice. | 2016 | Details |
| A19068 | 26785389 | Hepatol Res | The independent predictors of non-alcoholic steatohepatitis and its individual histological features.: Insulin resistance, serum uric acid, metabolic syndrome, alanine aminotransferase and serum total cholesterol are a clue to pathogenesis and candidate targets for treatment. | 2016 | Details |
| A19069 | 26784973 | Scand J Gastroenterol | Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease. | 2016 | Details |
| A19084 | 26774456 | Biochem Pharmacol | Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer. | 2016 | Details |
| A19085 | 26773785 | Nutr Res | Adzuki bean ameliorates hepatic lipogenesis and proinflammatory mediator expression in mice fed a high-cholesterol and high-fat diet to induce nonalcoholic fatty liver disease. | 2015 | Details |
| A19086 | 26773781 | Nutr Res | Chokeberry attenuates the expression of genes related to de novo lipogenesis in the hepatocytes of mice with nonalcoholic fatty liver disease. | 2015 | Details |
| A19088 | 26773297 | Hepatology | Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2016 | Details |
| A19090 | 26771611 | Int J Mol Sci | Nonalcoholic Fatty Liver Disease: Pros and Cons of Histologic Systems of Evaluation. | 2016 | Details |
| A19094 | 26770920 | Clin Mol Hepatol | Imaging findings of mimickers of hepatocellular carcinoma. | 2015 | Details |
| A19101 | 26768633 | Adv Clin Exp Med | The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test. | 2016 | Details |
| A19103 | 26764184 | Gastroenterology | Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes. | 2016 | Details |
| A19117 | 26753695 | Naunyn Schmiedebergs Arch Pharmacol | Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis. | 2016 | Details |
| A19118 | 26749582 | Aliment Pharmacol Ther | Aspirin use is associated with lower indices of liver fibrosis among adults in the United States. | 2016 | Details |
| A19147 | 26728181 | J Neuroinflammation | Non-alcoholic fatty liver disease induces signs of Alzheimer's disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model. | 2016 | Details |
| A19148 | 26728044 | BMC Cancer | MicroRNA expression analysis in high fat diet-induced NAFLD-NASH-HCC progression: study on C57BL/6J mice. | 2016 | Details |
| A19150 | 26727365 | PLoS One | Efficacy of Dietary Lipid Control in Healing High-Fat and High-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats. | 2016 | Details |
| A19158 | 26723251 | Biochem Biophys Res Commun | Suppressing cyclooxygenase-2 prevents nonalcoholic and inhibits apoptosis of hepatocytes that are involved in the Akt/p53 signal pathway. | 2015 | Details |
| A19159 | 26722832 | Atherosclerosis | Association between hepatic steatosis and serum liver enzyme levels with atrial fibrillation in the general population: The Study of Health in Pomerania (SHIP). | 2015 | Details |
| A19163 | 26718771 | Am J Physiol Gastrointest Liver Physiol | Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. | 2015 | Details |
| A19172 | 29953177 | Indian J Physiol Pharmacol | Herbal Induced Hepatoprotection and Hepatotoxicity: A Critical Review. | 2018 | Details |
| A19176 | 29889442 | Eksp Klin Gastroenterol | THE ROLE OF BILE ACIDS IN THE REGULATION OF LIPID AND CARBOHYDRATE METABOLISM IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE AND DIABETES TYPE2. | 2018 | Details |
| A19179 | 29630140 | Przegl Lek | [Endocrine abnormalities in liver diseases]. | 2018 | Details |
| A19189 | 28525217 | Rev Med Brux | [Psoriasis in 2016 : Co-morbidities and therapeutic update]. | 2019 | Details |
| A19190 | 28332698 | Mol Med | Induction of steatohepatitis (NASH) with insulin resistance in wildtype B6 mice by a western-type diet containing soybean oil and cholesterol. | 2017 | Details |
| A19196 | 26713058 | J Korean Med Sci | Vitamin D Status and Bone Mineral Density in Obese Children with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19208 | 26703097 | Trends Endocrinol Metab | The Role of Cholesterol in the Pathogenesis of NASH. | 2015 | Details |
| A19211 | 26699443 | J Gastroenterol Hepatol | Red pitaya betacyanins protects from diet-induced obesity, liver steatosis and insulin resistance in association with modulation of gut microbiota in mice. | 2016 | Details |
| A19214 | 26698665 | Free Radic Biol Med | Hepatocyte-specific Keap1 deletion reduces liver steatosis but not inflammation during non-alcoholic steatohepatitis development. | 2015 | Details |
| A19218 | 26697693 | Zhongguo Zhong Yao Za Zhi | Regulation of pure total flavonoids from Citrus on TH17/Treg balance in mice with NASH. | 2015 | Details |
| A19232 | 26683215 | Endocr Dev | Docosahexaenoic Acid and Its Role in G-Protein-Coupled Receptor 120 Activation in Children Affected by Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19233 | 26682925 | Biochem Biophys Res Commun | DSS colitis promotes tumorigenesis and fibrogenesis in a choline-deficient high-fat diet-induced NASH mouse model. | 2015 | Details |
| A19235 | 26681923 | Int J Biol Sci | A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis. | 2015 | Details |