Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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CLA3884 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02209 | 34459761 | Wiad Lek | ASSOCIATION ANALYSIS OF PIOGLITAZONE EFFECTIVENESS IN TREATMENT OF NAFLD PATIENTS WITH OBESITY AND PPARG RS1801282 (PRO12ALA) GENOTYPE. | 2021 | Details |
| A02248 | 34447235 | World J Gastroenterol | Advanced glycation end product: A potential biomarker for risk stratification of non-alcoholic fatty liver disease in ELSA-Brasil study. | 2021 | Details |
| A02252 | 34446090 | Diabetol Metab Syndr | Nonalcoholic fatty liver disease and the risk of insulin-requiring gestational diabetes. | 2021 | Details |
| A02273 | 34440592 | Life (Basel) | The Association between Low Muscle Mass and Hepatic Steatosis in Asymptomatic Population in Korea. | 2021 | Details |
| A02274 | 34440543 | Life (Basel) | Association between Activity and Brain-Derived Neurotrophic Factor in Patients with Non-Alcoholic Fatty Liver Disease: A Data-Mining Analysis. | 2021 | Details |
| A02293 | 34433590 | BMJ Open | Fatty liver index and progression to type 2 diabetes: a 5-year longitudinal study in Spanish workers with pre-diabetes. | 2021 | Details |
| A02307 | 34426178 | J Integr Med | Hepatic protective effects of Shenling Baizhu powder, a herbal compound, against inflammatory damage via TLR4/NLRP3 signalling pathway in rats with nonalcoholic fatty liver disease. | 2021 | Details |
| A02329 | 34416350 | Toxicology | Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent. | 2021 | Details |
| A02330 | 34416040 | Aliment Pharmacol Ther | Review article: non-alcoholic fatty liver disease and cardiovascular diseases: associations and treatment considerations. | 2021 | Details |
| A02333 | 34414956 | Medicine (Baltimore) | Relationship between serum uric acid level and nonalcoholic fatty liver disease in type 2 diabetes patients. | 2021 | Details |
| A02336 | 34414123 | Liver Cancer | Cabozantinib in Advanced Hepatocellular Carcinoma: Efficacy and Safety Data from an International Multicenter Real-Life Cohort. | 2021 | Details |
| A02339 | 34411553 | Metabolism | Nonalcoholic fatty liver disease increases the risk of diabetes in young adults: A nationwide population-based study in Korea. | 2021 | Details |
| A02341 | 34411400 | Liver Int | Bile acid dysmetabolism in the gut-microbiota-liver axis under hepatitis C virus infection. | 2021 | Details |
| A02354 | 34405583 | Nurs Open | A qualitative study of self-management experiences in people with non-alcoholic fatty liver disease. | 2021 | Details |
| A02365 | 34401690 | JHEP Rep | Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication. | 2021 | Details |
| A02369 | 34400217 | Metabolism | Diabetes and metabolic dysfunction-associated fatty liver disease. | 2021 | Details |
| A02378 | 34397807 | Medicine (Baltimore) | Relationship between Helicobacter pylori infection and nonalcoholic fatty liver disease: What should we expect from a meta-analysis? | 2021 | Details |
| A02380 | 34396890 | Arch Physiol Biochem | Hepatoprotection of capsaicin in alcoholic and non-alcoholic fatty liver diseases. | 2021 | Details |
| A02396 | 34389043 | Clin Epigenetics | A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease. | 2021 | Details |
| A02402 | 34385479 | Sci Rep | Fatty liver index as a predictor for type 2 diabetes in subjects with normoglycemia in a nationwide cohort study. | 2021 | Details |
| A02404 | 34384788 | J Lipid Res | Nonalcoholic fatty liver disease stratification by liver lipidomics. | 2021 | Details |
| A02416 | 34381983 | JHEP Rep | Histological activity despite normal ALT and IgG serum levels in patients with autoimmune hepatitis and cirrhosis. | 2021 | Details |
| A02432 | 34372774 | BMC Gastroenterol | Obesity and metabolic abnormalities as risks of alcoholic fatty liver in men: NAGALA study. | 2021 | Details |
| A02437 | 34371946 | Nutrients | Expression of Jejunal Taste Receptors in Women with Morbid Obesity. | 2021 | Details |
| A02457 | 34365005 | Magn Reson Imaging | Influence of arm position on proton density fat fraction in the liver using chemical shift-encoded magnetic resonance imaging. | 2021 | Details |
| A02465 | 34362228 | J Clin Med | Association of Body Composition and Sarcopenia with NASH in Obese Patients. | 2021 | Details |
| A02486 | 34357000 | Medicina (Kaunas) | Non-Alcoholic Fatty Liver Disease in Children. | 2021 | Details |
| A02491 | 34355155 | JHEP Rep | A dynamic association between myosteatosis and liver stiffness: Results from a prospective interventional study in obese patients. | 2021 | Details |
| A02499 | 34351306 | Horm Res Paediatr | Nonalcoholic Fatty Liver Disease in Children with Obesity: Narrative Review and Research Gaps. | 2021 | Details |
| A02500 | 34350519 | Dig Dis Sci | Endoscopic Ultrasound Finding of Diffuse Echogenicity in the Pancreas, Is It Relevant? | 2021 | Details |
| A02503 | 34349537 | Diabetes Metab Syndr Obes | Estimation of the Prevalence of Nonalcoholic Fatty Liver Disease in an Adult Population in Northern China Using the Data Mining Approach. | 2021 | Details |
| A02511 | 34346124 | Cell Prolif | Curcumol inhibits ferritinophagy to restrain hepatocyte senescence through YAP/NCOA4 in non-alcoholic fatty liver disease. | 2021 | Details |
| A02518 | 34343274 | Endocrinology | SGLT2 Inhibition for Cardiovascular Diseases, Chronic Kidney Disease, and NAFLD. | 2021 | Details |
| A02527 | 34340957 | Endocrinol Diabetes Nutr (Engl Ed) | Prevalence and predictors of non-alcoholic steatohepatitis in patients with morbid obesity. | 2021 | Details |
| A02556 | 34329714 | J Ethnopharmacol | Pharmacokinetic herb-disease-drug interactions: Effect of ginkgo biloba extract on the pharmacokinetics of pitavastatin, a substrate of Oatp1b2, in rats with non-alcoholic fatty liver disease. | 2021 | Details |
| A02563 | 34327759 | Phytother Res | Recent developments in the regulation of cholesterol transport by natural molecules. | 2021 | Details |
| A02567 | 34326946 | World J Diabetes | Exploring new treatment options for polycystic ovary syndrome: Review of a novel antidiabetic agent SGLT2 inhibitor. | 2021 | Details |
| A02583 | 34322898 | Hepatology | Guanine Nucleotide-Binding Protein G(i) Subunit Alpha 2 Exacerbates NASH Progression by Regulating Peroxiredoxin 1-Related Inflammation and Lipophagy. | 2021 | Details |
| A02588 | 34321846 | World J Gastroenterol | Advances in paediatric nonalcoholic fatty liver disease: Role of lipidomics. | 2021 | Details |
| A02589 | 34321839 | World J Gastroenterol | Incorporating mucosal-associated invariant T cells into the pathogenesis of chronic liver disease. | 2021 | Details |
| A02619 | 34307562 | World J Clin Cases | Impact of continuous positive airway pressure therapy for nonalcoholic fatty liver disease in patients with obstructive sleep apnea. | 2021 | Details |
| A02635 | 34300227 | J Clin Med | Insulin Resistance Is Not Increased in Inflammatory Bowel Disease Patients but Is Related to Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02644 | 34298870 | Int J Mol Sci | Liver Injury and the Macrophage Issue: Molecular and Mechanistic Facts and Their Clinical Relevance. | 2021 | Details |
| A02647 | 34298690 | Cancers (Basel) | Etiology and Outcomes of Hepatocellular Carcinoma in an Ethnically Diverse Population: The Multiethnic Cohort. | 2021 | Details |
| A02659 | 34294714 | Nat Commun | CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells. | 2021 | Details |
| A02665 | 34292604 | Hepatology | Salidroside Activates the AMP-Activated Protein Kinase Pathway to Suppress Nonalcoholic Steatohepatitis in Mice. | 2021 | Details |
| A02666 | 34292372 | J Gastroenterol | HBeAg-positive patients with HBsAg  < 100 IU/mL and negative HBV RNA have lower risk of virological relapse after nucleos(t)ide analogues cessation. | 2021 | Details |
| A02668 | 34291454 | Eur J Clin Invest | Omega-3 phospholipids and obesity-associated NAFLD: Potential mechanisms and therapeutic perspectives. | 2021 | Details |
| A02675 | 34289397 | J Hepatol | Maternal obesity increases the risk and severity of NAFLD in offspring. | 2021 | Details |
| A02688 | 34282076 | J Chin Med Assoc | Deep learning for abdominal ultrasound: A computer-aided diagnostic system for the severity of fatty liver. | 2021 | Details |
| A02699 | 34278728 | Physiol Rep | Lean non-alcoholic fatty liver disease and associated metabolic disturbance: A Saudi Arabian cross-sectional study. | 2021 | Details |
| A02700 | 34278170 | Hepatol Commun | Colonoscopy and Risk of Colorectal Cancer in Patients With Nonalcoholic Fatty Liver Disease: A Retrospective Territory-Wide Cohort Study. | 2021 | Details |
| A02740 | 34263707 | Expert Rev Gastroenterol Hepatol | Metabolic-associated fatty liver disease and autoimmune hepatitis: an overlooked interaction. | 2021 | Details |
| A02741 | 34263075 | JGH Open | Validation of a two-step approach combining serum biomarkers and liver stiffness measurement to predict advanced fibrosis. | 2021 | Details |
| A02778 | 34244048 | Nutr Metab Cardiovasc Dis | Early identification of metabolic syndrome risk: A review of reviews and proposal for defining pre-metabolic syndrome status. | 2021 | Details |
| A02789 | 34239698 | World J Hepatol | Glutathione-S-transferases genes-promising predictors of hepatic dysfunction. | 2021 | Details |
| A02798 | 34235516 | Food Funct | The interaction between gut microbiota and flavonoid extract from Smilax glabra Roxb. and its potent alleviation of fatty liver. | 2021 | Details |
| A02805 | 34234198 | Sci Rep | Utility of Fibroscan XL to assess the severity of non-alcoholic fatty liver disease in patients undergoing bariatric surgery. | 2021 | Details |
| A02807 | 34233850 | Hepatobiliary Pancreat Dis Int | Key factors and potential drug combinations of nonalcoholic steatohepatitis: Bioinformatic analysis and experimental validation-based study. | 2021 | Details |
| A02816 | 34231477 | Turk J Gastroenterol | Feasibility of Fibroscan in Assessment of Hepatic Steatosis and Fibrosis in Obese Patients: Report From a General Internal Medicine Clinic. | 2021 | Details |
| A02826 | 34228977 | Biochimie | Citrin deficiency: Does the reactivation of liver aralar-1 come into play and promote HCC development? | 2021 | Details |
| A02862 | 34213039 | J Clin Lab Anal | Risk of severe illness of COVID-19 patients with NAFLD and increased NAFLD fibrosis scores. | 2021 | Details |
| A02867 | 34211743 | Curr Health Sci J | Assessment of Left Ventricular Diastolic Function in Young Adults with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02893 | 34204225 | Entropy (Basel) | Assessment of Classification Models and Relevant Features on Nonalcoholic Steatohepatitis Using Random Forest. | 2021 | Details |
| A02896 | 34203342 | Metabolites | Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02904 | 34202179 | Int J Mol Sci | The Alterations of Mitochondrial Function during NAFLD Progression-An Independent Effect of Mitochondrial ROS Production. | 2021 | Details |
| A02907 | 34201230 | Pediatr Rep | Diagnosis and Staging of Pediatric Non-Alcoholic Fatty Liver Disease: Is Classical Ultrasound the Answer? | 2021 | Details |
| A02909 | 34200685 | Metabolites | Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl4-Induced NASH Mice and the Effect of Obeticholic Acid. | 2021 | Details |
| A02911 | 34200577 | Metabolites | Circulating Levels of Pro-Neurotensin and Its Relationship with Nonalcoholic Steatohepatitis and Hepatic Lipid Metabolism. | 2021 | Details |
| A02921 | 34198988 | Int J Mol Sci | Deregulation of Secreted Frizzled-Related Protein 5 in Nonalcoholic Fatty Liver Disease Associated with Obesity. | 2021 | Details |
| A02922 | 34198964 | Antibiotics (Basel) | Nonalcoholic Fatty Liver Disease-A Novel Risk Factor for Recurrent Clostridioides difficile Infection. | 2021 | Details |
| A02932 | 34192596 | Life Sci | Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice. | 2021 | Details |
| A02933 | 34192533 | Cell Rep | Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release. | 2021 | Details |
| A02934 | 34192532 | Cell Rep | A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity. | 2021 | Details |
| A02942 | 34190160 | Medicine (Baltimore) | A nomogram incorporated lifestyle indicators for predicting nonalcoholic fatty liver disease. | 2021 | Details |
| A02947 | 34188101 | Sci Rep | Nonalcoholic fatty liver disease is associated with the development of obstructive sleep apnea. | 2021 | Details |
| A02961 | 34183709 | Sci Rep | The mechanism of increased intestinal palmitic acid absorption and its impact on hepatic stellate cell activation in nonalcoholic steatohepatitis. | 2021 | Details |
| A02967 | 34181776 | Aliment Pharmacol Ther | Internal medicine hospitalisations and liver disease: a comparative disease burden analysis of a multicentre cohort. | 2021 | Details |
| A02975 | 34176541 | Br J Nutr | Sex influences the association between appendicular skeletal muscle mass to visceral fat area ratio and non-alcoholic steatohepatitis in patients with biopsy-proven non-alcoholic fatty liver disease. | 2021 | Details |
| A02985 | 34174011 | Liver Int | Ultra-processed food is associated with features of metabolic syndrome and non-alcoholic fatty liver disease. | 2021 | Details |
| A02991 | 34171931 | Z Gastroenterol | Conventional ultrasound for diagnosis of hepatic steatosis is better than believed. | 2021 | Details |
| A03004 | 34168277 | Int J Obes (Lond) | Performance of non-invasive fibrosis scores in non-alcoholic fatty liver disease with and without morbid obesity. | 2021 | Details |
| A03021 | 34160377 | Am J Gastroenterol | Fibrosis-4 Index vs Nonalcoholic Fatty Liver Disease Fibrosis Score in Identifying Advanced Fibrosis in Subjects With Nonalcoholic Fatty Liver Disease: A Meta-Analysis. | 2021 | Details |
| A03040 | 34155798 | Liver Int | Non-alcoholic fatty liver disease in type 2 diabetes - A specific entity? | 2021 | Details |
| A03054 | 34152626 | Aliment Pharmacol Ther | Screening for compensated advanced chronic liver disease using refined Baveno VI elastography cutoffs in Asian patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A03057 | 34151600 | Physiol Genomics | Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD. | 2021 | Details |
| A03105 | 34129272 | Hepatol Res | MAFLD better predicts the progression of atherosclerotic cardiovascular risk than NAFLD: Generalized estimating equation approach. | 2021 | Details |
| A03111 | 34126105 | J Hepatol | Development and prognostic relevance of a histologic grading and staging system for alcohol-related liver disease. | 2021 | Details |
| A03114 | 34125646 | Gut Microbes | Desulfovibrio vulgaris, a potent acetic acid-producing bacterium, attenuates nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A03157 | 34107897 | BMC Pediatr | Prevalence of increased transaminases and its association with sex, age, and metabolic parameters in children and adolescents with obesity - a nationwide cross-sectional cohort study. | 2021 | Details |
| A03165 | 34106587 | Medicine (Baltimore) | Xuefu Zhuyu decoction for nonalcoholic fatty liver disease: A protocol for systematic review and meta-analysis. | 2021 | Details |
| A03200 | 34092291 | Chin J Nat Med | Silybin alleviates hepatic lipid accumulation in methionine-choline deficient diet-induced nonalcoholic fatty liver disease in mice via peroxisome proliferator-activated receptor α. | 2021 | Details |
| A03203 | 34091049 | Clin Gastroenterol Hepatol | A Polygenic Risk Score to Refine Risk Stratification and Prediction for Severe Liver Disease by Clinical Fibrosis Scores. | 2021 | Details |
| A03211 | 34088709 | BMJ Open | Is there scope to improve the selection of patients with alcohol-related liver disease for referral to secondary care? A retrospective analysis of primary care referrals to a UK liver centre, incorporating simple blood tests. | 2021 | Details |
| A03226 | 34081289 | Hepatol Int | Histological severity of nonalcoholic fatty liver disease is associated with 10-year risk for atherosclerotic cardiovascular disease. | 2021 | Details |
| A03251 | 34070938 | Int J Mol Sci | Magnesium Isoglycyrrhizinate Reduces Hepatic Lipotoxicity through Regulating Metabolic Abnormalities. | 2021 | Details |
| A03261 | 34067649 | Metabolites | Role of Steroid Hormones in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03262 | 34067258 | Int J Mol Sci | Non-Obese MAFLD Is Associated with Colorectal Adenoma in Health Check Examinees: A Multicenter Retrospective Study. | 2021 | Details |
| A03270 | 34065140 | Children (Basel) | Update on Metabolic Bariatric Surgery for Morbidly Obese Adolescents. | 2021 | Details |
| A03277 | 34064337 | J Clin Med | Correlation between Liver Stiffness by Two-Dimensional Shear Wave Elastography and Waist Circumference in Japanese Local Citizens with Abdominal Obesity. | 2021 | Details |