Research Articles

Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.

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     Rapamycin
222 records.
Article ID PMID Source Title Publish Year
A50164 35495903 Front Nutr Amino Acid and Fatty Acid Metabolism Disorders Trigger Oxidative Stress and Inflammatory Response in Excessive Dietary Valine-Induced NAFLD of Laying Hens. 2022 Details
A50248 35457142 Int J Mol Sci Role of Branched-Chain Amino Acid Metabolism in Type 2 Diabetes, Obesity, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease. 2022 Details
A50313 35436113 J Agric Food Chem Protective Effect and Mechanism of Plant-Based Monoterpenoids in Non-alcoholic Fatty Liver Diseases. 2022 Details
A50353 35420934 Science Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1. 2022 Details
A50354 35420931 Science Complex regulation of fatty liver disease. 2022 Details
A50470 35378066 Cell Mol Gastroenterol Hepatol Something to mTORC About in NASH. 2022 Details
A50563 35339509 Life Sci Autophagic dysfunction in the liver enhances the expression of insoluble nuclear proteins 14-3-3ζ and importin α4. 2022 Details
A50911 33731774 Acta Pharmacol Sin Role of the mTOR-autophagy-ER stress pathway in high fructose-induced metabolic-associated fatty liver disease. 2021 Details
A51157 35447117 J Biol Chem Calpain-mediated proteolytic production of free amino acids in vascular endothelial cells augments obesity-induced hepatic steatosis. 2022 Details
A51161 35427802 Clin Res Hepatol Gastroenterol The mTORC1/AMPK pathway plays a role in the beneficial effects of semaglutide (GLP-1 receptor agonist) on the liver of obese mice. 2022 Details
A51185 35297334 Exp Clin Transplant How Exercise Affects the Development and Progression of Hepatocellular Carcinoma by Changing the Biomolecular Status of the Tumor Microenvironment. 2022 Details
A52005 32432943 Autophagy Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway. 2020 Details
A52019 32231246 Cell Death Differ OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer. 2020 Details
A52030 32128655 Rev Endocr Metab Disord Type 2 diabetes - unmet need, unresolved pathogenesis, mTORC1-centric paradigm. 2020 Details
A52043 31944172 Autophagy Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells. 2020 Details
A52096 31307210 FASEB J Ileal interposition surgery targets the hepatic TGF-β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD-T2DM rat model of diabetes. 2019 Details
A52214 30040479 Am J Physiol Endocrinol Metab Differential contribution of chronic binge alcohol and antiretroviral therapy to metabolic dysregulation in SIV-infected male macaques. 2018 Details
A52279 29371333 Eur J Endocrinol MECHANISMS IN ENDOCRINOLOGY: SGLT2 inhibitors: clinical benefits by restoration of normal diurnal metabolism? 2018 Details
A52347 28275691 Cell Mol Gastroenterol Hepatol Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1-AKT-mTOR Axis in Mice. 2016 Details
A52423 27257602 Mol Metab Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease. 2016 Details
A52679 23669346 Biochim Biophys Acta Ketogenic essential amino acids replacement diet ameliorated hepatosteatosis with altering autophagy-associated molecules. 2013 Details
A52893 19859993 World J Gastroenterol Steatosis and insulin resistance in hepatitis C: a way out for the virus? 2009 Details