Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A08860 | 31959914 | Cell Death Differ | Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH. | 2020 | Details |
A08891 | 31950772 | Diabetes Metab J | Combination of Probiotics and Salvia miltiorrhiza Polysaccharide Alleviates Hepatic Steatosis via Gut Microbiota Modulation and Insulin Resistance Improvement in High Fat-Induced NAFLD Mice. | 2019 | Details |
A08892 | 31950587 | J Dig Dis | Effects and therapeutic mechanism of Yinzhihuang on steatohepatitis in rats induced by a high-fat, high-cholesterol diet. | 2020 | Details |
A09006 | 31907123 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | [Intervention of Catalpol on High-fat Diet Induced Nonalcoholic Fatty Liver Disease in Mice]. | 2019 | Details |
A09019 | 31902937 | Biol Pharm Bull | Repeated Administration of Kupffer Cells-Targeting Nanoantioxidant Ameliorates Liver Fibrosis in an Experimental Mouse Model. | 2020 | Details |
A09035 | 31896166 | J Gastroenterol Hepatol | Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases. | 2020 | Details |
A09069 | 31885541 | Gastroenterol Res Pract | Systematic Review with Meta-Analysis: The Effects of Probiotics in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
A09087 | 31881201 | Exp Mol Pathol | Alpha-syntrophin deficiency protects against non-alcoholic steatohepatitis associated increase of macrophages, CD8+ T-cells and galectin-3 in the liver. | 2019 | Details |
A09101 | 31876010 | Microcirculation | Pyridoxamine improves metabolic and microcirculatory complications associated with nonalcoholic fatty liver disease. | 2020 | Details |
A09112 | 31870134 | Korean J Intern Med | Liver enzyme elevation in patients with ankylosing spondylitis treated with tumor necrosis factor inhibitors: a single-center historical cohort study. | 2019 | Details |
A09156 | 31853615 | Naunyn Schmiedebergs Arch Pharmacol | Adelmidrol protects against non-alcoholic steatohepatitis in mice. | 2019 | Details |
A09300 | 31800592 | PLoS One | Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis. | 2019 | Details |
A09317 | 31793207 | J Cell Mol Med | PNPLA3 I148M mediates the regulatory effect of NF-kB on inflammation in PA-treated HepG2 cells. | 2019 | Details |
A09350 | 31782176 | Hepatology | Lipotoxic Hepatocyte-Derived Exosomal MicroRNA 192-5p Activates Macrophages Through Rictor/Akt/Forkhead Box Transcription Factor O1 Signaling in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A09386 | 31766373 | J Clin Med | Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review. | 2019 | Details |
A09460 | 31737175 | Oxid Med Cell Longev | Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients. | 2019 | Details |
A09539 | 31702809 | Mol Med Rep | Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet. | 2019 | Details |
A09557 | 31695251 | J Clin Exp Hepatol | Molecular and Pathological Events Involved in the Pathogenesis of Diabetes-Associated Nonalcoholic Fatty Liver Disease. | 2018 | Details |
A09589 | 31684925 | BMC Complement Altern Med | The potential of antioxidant-rich Maoberry (Antidesma bunius) extract on fat metabolism in liver tissues of rats fed a high-fat diet. | 2019 | Details |
A09649 | 31659105 | Cancer Genomics Proteomics | Synergism of Adipocytokine Profile and ADIPOQ/TNF-α Polymorphisms in NAFLD-associated MetS Predict Colorectal Liver Metastases Outgrowth. | 2020 | Details |
A09822 | 31598135 | Therap Adv Gastroenterol | Effects of probiotics on nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2019 | Details |
A09853 | 31591383 | Cell Death Dis | Progranulin attenuates liver fibrosis by downregulating the inflammatory response. | 2019 | Details |
A09881 | 31576092 | World J Gastroenterol | Zinc-α2-glycoprotein 1 attenuates non-alcoholic fatty liver disease by negatively regulating tumour necrosis factor-α. | 2019 | Details |
A09892 | 31572482 | Arch Med Sci | Effect of Lactobacillus paracasei N1115 and fructooligosaccharides in nonalcoholic fatty liver disease. | 2019 | Details |
A09924 | 31558860 | World J Gastroenterol | Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease. | 2019 | Details |
A09967 | 31541591 | J Pineal Res | Melatonin safeguards against fatty liver by antagonizing TRAFs-mediated ASK1 deubiquitination and stabilization in a β-arrestin-1 dependent manner. | 2019 | Details |
A10058 | 31506421 | Exp Mol Med | Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats. | 2019 | Details |
A10062 | 31505462 | J Endocrinol | Mice lacking adenosine 2A receptor reveal increased severity of MCD-induced NASH. | 2019 | Details |
A10065 | 31505040 | Hepatology | Hepatocyte Stress Increases Expression of Yes-Associated Protein and Transcriptional Coactivator With PDZ-Binding Motif in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis. | 2020 | Details |
A10071 | 31503268 | Food Funct | Green tea extract inhibits early oncogenic responses in mice with nonalcoholic steatohepatitis. | 2019 | Details |
A10082 | 31496048 | Physiol Rep | Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. | 2019 | Details |
A10093 | 31489674 | J Food Biochem | Dietary chia seeds (Salvia hispanica) improve acute dyslipidemia and steatohepatitis in rats. | 2019 | Details |
A10099 | 31484323 | Nutrients | Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress. | 2019 | Details |
A10110 | 31480575 | Biomolecules | Raw Bowl Tea (Tuocha) Polyphenol Prevention of Nonalcoholic Fatty Liver Disease by Regulating Intestinal Function in Mice. | 2019 | Details |
A10112 | 31479282 | Expert Opin Drug Saf | The safety of anti-interleukins monoclonal antibodies for the treatment of psoriasis. | 2019 | Details |
A10115 | 31477174 | Stem Cell Res Ther | Antioxidant-upregulated mesenchymal stem cells reduce inflammation and improve fatty liver disease in diet-induced obesity. | 2019 | Details |
A10121 | 31474792 | Ann Gastroenterol | High prevalence of non-alcoholic fatty liver disease in patients with inflammatory bowel disease receiving anti-tumor necrosis factor therapy. | 2019 | Details |
A10166 | 31462971 | Comput Struct Biotechnol J | Hallmarks of Aging in the Liver. | 2019 | Details |
A10169 | 31456946 | Front Oncol | Recent Insights Into the Multiple Pathways Driving Non-alcoholic Steatohepatitis-Derived Hepatocellular Carcinoma. | 2019 | Details |
A10193 | 31440940 | Inflammation | Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells. | 2019 | Details |
A10196 | 31438528 | Mar Drugs | Indole-4-carboxaldehyde Isolated from Seaweed, Sargassum thunbergii, Attenuates Methylglyoxal-Induced Hepatic Inflammation. | 2019 | Details |
A10215 | 31428351 | Food Sci Nutr | Lactobacillus paracasei Jlus66 extenuate oxidative stress and inflammation via regulation of intestinal flora in rats with non alcoholic fatty liver disease. | 2019 | Details |
A10261 | 31408278 | IUBMB Life | Silencing of lncRNA SNHG20 delays the progression of nonalcoholic fatty liver disease to hepatocellular carcinoma via regulating liver Kupffer cells polarization. | 2019 | Details |
A10279 | 31401392 | Biomed Pharmacother | Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice. | 2019 | Details |
A10316 | 31388695 | Diabetologia | Genetic inactivation of the LIGHT (TNFSF14) cytokine in mice restores glucose homeostasis and diminishes hepatic steatosis. | 2019 | Details |
A10328 | 31387231 | Antioxidants (Basel) | Lycopene Modulates Pathophysiological Processes of Non-Alcoholic Fatty Liver Disease in Obese Rats. | 2019 | Details |
A10367 | 31372694 | Naunyn Schmiedebergs Arch Pharmacol | Chrysin ameliorates nonalcoholic fatty liver disease in rats. | 2019 | Details |
A10385 | 31361003 | Nutr Rev | Effect of dietary intervention, with or without co-interventions, on inflammatory markers in patients with nonalcoholic fatty liver disease: a systematic literature review. | 2019 | Details |
A10415 | 31345163 | BMC Gastroenterol | Curcumin and inflammation in non-alcoholic fatty liver disease: a randomized, placebo controlled clinical trial. | 2019 | Details |
A10469 | 31324181 | Nutr J | The effect of total anthocyanin-base standardized (Cornus mas L.) fruit extract on liver function, tumor necrosis factor α, malondealdehyde, and adiponectin in patients with non-alcoholic fatty liver: a study protocol for a double-blind randomized clinical trial. | 2019 | Details |
A10475 | 31322211 | Mol Med Rep | Ascorbic acid attenuates cell stress by activating the fibroblast growth factor 21/fibroblast growth factor receptor 2/adiponectin pathway in HepG2 cells. | 2019 | Details |
A10495 | 31311491 | BMC Gastroenterol | Low vitamin D level was associated with metabolic syndrome and high leptin level in subjects with nonalcoholic fatty liver disease: a community-based study. | 2019 | Details |
A10515 | 31307427 | BMC Gastroenterol | A new method to induce nonalcoholic steatohepatitis (NASH) in mice. | 2019 | Details |
A10546 | 31293341 | World J Gastroenterol | Freeze-dried Si-Ni-San powder can ameliorate high fat diet-induced non-alcoholic fatty liver disease. | 2019 | Details |
A10557 | 31291245 | PLoS One | Assay validation and clinical performance of chronic inflammatory and chemokine biomarkers of NASH fibrosis. | 2019 | Details |
A10562 | 31290703 | J Med Food | Lycopene and Tomato Sauce Improve Hepatic and Cardiac Cell Biomarkers in Rats. | 2019 | Details |
A10628 | 31264313 | Phytother Res | Hesperidin improves hepatic steatosis, hepatic enzymes, and metabolic and inflammatory parameters in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled, double-blind clinical trial. | 2019 | Details |
A10696 | 31233751 | Eur J Pharmacol | Zoledronic acid prevents the hepatic changes associated with high fat diet in rats; the potential role of mevalonic acid pathway in nonalcoholic steatohepatitis. | 2019 | Details |
A10735 | 31216264 | J Pediatr Endocrinol Metab | Genetic polymorphisms associated with obesity and non-alcoholic fatty liver disease in Asian Indian adolescents. | 2019 | Details |
A10740 | 31214277 | Oxid Med Cell Longev | TNFα-Mediated Necroptosis Aggravates Ischemia-Reperfusion Injury in the Fatty Liver by Regulating the Inflammatory Response. | 2019 | Details |
A10750 | 31211018 | PeerJ | Impact of body weight gain on hepatic metabolism and hepatic inflammatory cytokines in comparison of Shetland pony geldings and Warmblood horse geldings. | 2019 | Details |
A10761 | 31206703 | J Physiol | Anti-inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid-induced insulin resistance. | 2019 | Details |
A10768 | 31203554 | Dig Dis Sci | Efficacy of Probiotics and Synbiotics in Patients with Nonalcoholic Fatty Liver Disease: A Meta-Analysis. | 2019 | Details |
A10810 | 31177662 | Zhonghua Gan Zang Bing Za Zhi | [Correlation analysis of gut microbiota and biochemical indexes in patients with non-alcoholic fatty liver disease]. | 2019 | Details |
A10822 | 31173200 | Mol Med Rep | Diallyl disulfide attenuates non‑alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, lipid peroxidation and inflammation in mice. | 2019 | Details |
A10865 | 31151002 | J Mech Behav Biomed Mater | Biomechanics of cultured hepatic cells during different steatogenic hits. | 2019 | Details |
A10916 | 31126557 | Complement Ther Med | Nigella sativa and inflammatory biomarkers in patients with non-alcoholic fatty liver disease: Results from a randomized, double-blind, placebo-controlled, clinical trial. | 2019 | Details |
A10995 | 31087530 | Physiol Rep | Whole-body vibration for patients with nonalcoholic fatty liver disease: a 6-month prospective study. | 2019 | Details |
A11007 | 31083413 | Int J Mol Sci | Arazyme Suppresses Hepatic Steatosis and Steatohepatitis in Diet-Induced Non-Alcoholic Fatty Liver Disease-Like Mouse Model. | 2019 | Details |
A11070 | 31060228 | Biomolecules | Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague⁻Dawley Rats †. | 2019 | Details |
A11083 | 31051410 | Atherosclerosis | The novel adipokine CTRP1 is significantly associated with the incidence of major adverse cardiovascular events. | 2019 | Details |
A11087 | 31048208 | J Nutr Biochem | Metabolic dysfunction following weight regain compared to initial weight gain in a high-fat diet-induced obese mouse model. | 2019 | Details |
A11176 | 31010354 | Free Radic Res | Evaluation of the therapeutic potential effect of Fas receptor gene knockdown in experimental model of non-alcoholic steatohepatitis. | 2019 | Details |
A11181 | 31009401 | Eur J Gastroenterol Hepatol | The promising role of probiotic and synbiotic therapy in aminotransferase levels and inflammatory markers in patients with nonalcoholic fatty liver disease - a systematic review and meta-analysis. | 2019 | Details |
A11195 | 31004566 | Biochem Pharmacol | Telmisartan and/or chlorogenic acid attenuates fructose-induced non-alcoholic fatty liver disease in rats: Implications of cross-talk between angiotensin, the sphingosine kinase/sphingoine-1-phosphate pathway, and TLR4 receptors. | 2019 | Details |
A11223 | 30987167 | Int J Mol Sci | Ameliorative Effect of Spinach on Non-Alcoholic Fatty Liver Disease Induced in Rats by a High-Fat Diet. | 2019 | Details |
A11253 | 30973105 | Comb Chem High Throughput Screen | Effect of Chinese Herbal Monomer Hairy Calycosin on Nonalcoholic Fatty Liver Rats and its Mechanism. | 2019 | Details |
A11295 | 30951375 | FASEB J | The immunoregulatory effects of CD8 T-cell-derived perforin on diet-induced nonalcoholic steatohepatitis. | 2019 | Details |
A11316 | 30942432 | Int J Mol Med | Oxaliplatin aggravates hepatic oxidative stress, inflammation and fibrosis in a non‑alcoholic fatty liver disease mouse model. | 2019 | Details |
A11323 | 30937936 | J Cell Physiol | Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes. | 2019 | Details |
A11325 | 30937580 | Eur J Nutr | Erythrocyte membrane n-3 polyunsaturated fatty acids are inversely associated with the presence and progression of nonalcoholic fatty liver disease in Chinese adults: a prospective study. | 2019 | Details |
A11392 | 30915409 | Clin Exp Hepatol | Allopurinol potentiates the hepatoprotective effect of metformin and vitamin E in fructose-induced fatty liver in rats. | 2019 | Details |
A11396 | 30914267 | J Hepatol | Macrophage p38α promotes nutritional steatohepatitis through M1 polarization. | 2019 | Details |
A11400 | 30912307 | Physiol Rep | The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats. | 2019 | Details |
A11497 | 30871035 | Nutrients | Eicosapentaenoic Acid Improves Hepatic Metabolism and Reduces Inflammation Independent of Obesity in High-Fat-Fed Mice and in HepG2 Cells. | 2019 | Details |
A11558 | 30841442 | Biomed Pharmacother | Genistein can ameliorate hepatic inflammatory reaction in nonalcoholic steatohepatitis rats. | 2019 | Details |
A11569 | 30835899 | J Leukoc Biol | Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis. | 2019 | Details |
A11595 | 30825110 | Dig Dis Sci | Antifibrotic Effects of 1,25(OH)2D3 on Nonalcoholic Steatohepatitis in Female Mice. | 2019 | Details |
A11601 | 30824190 | Biochem Biophys Res Commun | NLRC4 inflammasome activation regulated by TNF-α promotes inflammatory responses in nonalcoholic fatty liver disease. | 2019 | Details |
A11604 | 30823334 | Environ Pollut | Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines. | 2019 | Details |
A11638 | 30809789 | Semin Liver Dis | Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets. | 2019 | Details |
A11676 | 30793717 | Food Funct | Activated TNF-α/RIPK3 signaling is involved in prolonged high fat diet-stimulated hepatic inflammation and lipid accumulation: inhibition by dietary fisetin intervention. | 2019 | Details |
A11746 | 30767788 | BMC Res Notes | Inflammatory markers response to citrulline supplementation in patients with non-alcoholic fatty liver disease: a randomized, double blind, placebo-controlled, clinical trial. | 2019 | Details |
A11771 | 30757944 | Pharm Biol | Hepatoprotective effects of Cassia semen ethanol extract on non-alcoholic fatty liver disease in experimental rat. | 2019 | Details |
A11780 | 30746959 | Rev Esp Enferm Dig | Comparative study of overweight and obese patients with nonalcoholic fatty liver disease. | 2019 | Details |
A11790 | 30744124 | Mar Drugs | Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-deficient Diet. | 2019 | Details |
A11796 | 30737662 | Inflammation | Saroglitazar Deactivates the Hepatic LPS/TLR4 Signaling Pathway and Ameliorates Adipocyte Dysfunction in Rats with High-Fat Emulsion/LPS Model-Induced Non-alcoholic Steatohepatitis. | 2019 | Details |
A11823 | 30720104 | Mol Med Rep | Tetramethylpyrazine reduces inflammation in the livers of mice fed a high fat diet. | 2019 | Details |
A11862 | 30705687 | Nutr Metab (Lond) | Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial. | 2019 | Details |
A11874 | 30701776 | Ter Arkh | Intrahepatic cholestasis in nonalcoholic fatty liver disease. | 2018 | Details |