Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A01381 | 34768440 | J Clin Med | Prothrombotic and Inflammatory Markers in Elderly Patients with Non-Alcoholic Hepatic Liver Disease before and after Weight Loss: A Pilot Study. | 2021 | Details |
| A01396 | 34761883 | Minerva Med | Inflammatory-nutritional scores in the diagnosis of NASH and liver fibrosis. | 2021 | Details |
| A01405 | 34758532 | Zhonghua Yi Xue Za Zhi | [Analysis of hub genes and molecular mechanisms in non-alcoholic steatohepatitis based on the gene expression omnibus database]. | 2021 | Details |
| A01406 | 34758326 | Cell Rep | m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity. | 2021 | Details |
| A01413 | 34757046 | Mol Metab | Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis. | 2021 | Details |
| A01416 | 34755918 | Environ Toxicol | Polystyrene nanoplastics potentiate the development of hepatic fibrosis in high fat diet fed mice. | 2021 | Details |
| A01428 | 34752711 | Annu Rev Pathol | Role of the Inflammasome in Liver Disease. | 2021 | Details |
| A01429 | 34750345 | Sci Rep | Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility. | 2021 | Details |
| A01440 | 34745924 | Avicenna J Phytomed | Gallic acid protects the liver against NAFLD induced by dust exposure and high-fat diet through inhibiting oxidative stress and repressing the inflammatory signaling pathways NF-kβ/TNF-α/IL-6 in Wistar rats. | 2022 | Details |
| A01442 | 34745017 | Front Endocrinol (Lausanne) | The Role of RECK in Hepatobiliary Neoplasia Reveals Its Therapeutic Potential in NASH. | 2021 | Details |
| A01443 | 34743980 | Eur J Pharmacol | Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms. | 2021 | Details |
| A01455 | 34741169 | Nat Rev Immunol | Immune cell-mediated features of non-alcoholic steatohepatitis. | 2021 | Details |
| A01460 | 34740314 | Mol Med | Nuclear receptors: a bridge linking the gut microbiome and the host. | 2021 | Details |
| A01465 | 34737604 | J Inflamm Res | Curcumae Ameliorates Diethylnitrosamine-Induced Hepatocellular Carcinoma via Alteration of Oxidative Stress, Inflammation and Gut Microbiota. | 2021 | Details |
| A01475 | 34734369 | J Gastrointest Surg | The Role of Gut-Derived Lipopolysaccharides and the Intestinal Barrier in Fatty Liver Diseases. | 2021 | Details |
| A01476 | 34734090 | J Immunol Res | Mangiferin Ameliorates HFD-Induced NAFLD through Regulation of the AMPK and NLRP3 Inflammasome Signal Pathways. | 2021 | Details |
| A01477 | 34733981 | Ann Transl Med | TLR2 inhibition ameliorates the amplification effect of LPS on lipid accumulation and lipotoxicity in hepatic cells. | 2021 | Details |
| A01479 | 34732369 | Pharmacol Res | Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease. | 2021 | Details |
| A01488 | 34727379 | Biomed Chromatogr | Lipidomic-based investigation into the therapeutic effects of polyene phosphatidylcholine and Babao Dan on rats with non-alcoholic fatty liver disease. | 2021 | Details |
| A01490 | 34726357 | J Pediatr Endocrinol Metab | Increased hepcidin levels and non-alcoholic fatty liver disease in obese prepubertal children: a further piece to the complex puzzle of metabolic derangements. | 2021 | Details |
| A01498 | 34722615 | Front Nutr | Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice. | 2021 | Details |
| A01501 | 34722019 | Cureus | Decoding the Pathophysiology of Non-alcoholic Fatty Liver Disease Progressing to Non-alcoholic Steatohepatitis: A Systematic Review. | 2021 | Details |
| A01508 | 34717194 | Int Immunopharmacol | Oridonin regulates the polarized state of Kupffer cells to alleviate nonalcoholic fatty liver disease through ROS-NF-κB. | 2021 | Details |
| A01509 | 34717002 | Hepatology | Breviscapine alleviates NASH by inhibiting TGF-β-activated kinase 1-dependent signaling. | 2021 | Details |
| A01527 | 34707687 | Therap Adv Gastroenterol | Safety of anti-TNF agents in patients with compensated cirrhosis: a case-control study. | 2021 | Details |
| A01538 | 34706243 | Cell Rep | Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease. | 2021 | Details |
| A01543 | 34704005 | JHEP Rep | PI3Kγ promotes obesity-associated hepatocellular carcinoma by regulating metabolism and inflammation. | 2021 | Details |
| A01544 | 34703257 | Diabetes Metab Syndr Obes | QSHY Granules Promote White Adipose Tissue Browning and Correct BCAAs Metabolic Disorder in NAFLD Mice. | 2021 | Details |
| A01550 | 34697666 | Handb Exp Pharmacol | Obesity and Obstructive Sleep Apnea. | 2021 | Details |
| A01552 | 34697380 | Sci Rep | Untargeted serum metabolites profiling in high-fat diet mice supplemented with enhanced palm tocotrienol-rich fraction using UHPLC-MS. | 2021 | Details |
| A01556 | 34694070 | Mol Syst Biol | Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients. | 2021 | Details |
| A01558 | 34694013 | Aliment Pharmacol Ther | Liver biopsy in the real world-reporting, expert concordance and correlation with a pragmatic clinical diagnosis. | 2021 | Details |
| A01571 | 34689362 | Hepatology | Switch-associated protein 70 protects against nonalcoholic fatty liver disease via suppression of TAK1. | 2022 | Details |
| A01574 | 34688661 | J Biol Chem | A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease. | 2021 | Details |
| A01577 | 34687092 | Biofactors | Perspectives in liver redox imbalance: Toxicological and pharmacological aspects underlying iron overloading, nonalcoholic fatty liver disease, and thyroid hormone action. | 2021 | Details |
| A01583 | 34685496 | Cells | Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression. | 2021 | Details |
| A01587 | 34684533 | Nutrients | Supplementation with a Specific Combination of Metabolic Cofactors Ameliorates Non-Alcoholic Fatty Liver Disease, Hepatic Fibrosis, and Insulin Resistance in Mice. | 2021 | Details |
| A01590 | 34684455 | Nutrients | Zonarol Protected Liver from Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease in a Mouse Model. | 2021 | Details |
| A01601 | 34681695 | Int J Mol Sci | Astaxanthin Prevents Diet-Induced NASH Progression by Shaping Intrahepatic Immunity. | 2021 | Details |
| A01609 | 34680522 | Biomedicines | Lipid Disorders in NAFLD and Chronic Kidney Disease. | 2021 | Details |
| A01611 | 34680486 | Biomedicines | Nonalcoholic Fatty Liver Disease and the Kidney: A Review. | 2021 | Details |
| A01622 | 34678374 | Toxicol Appl Pharmacol | Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3. | 2021 | Details |
| A01631 | 34675931 | Front Immunol | Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice. | 2021 | Details |
| A01634 | 34675338 | Sci Rep | Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis. | 2021 | Details |
| A01638 | 34674097 | Inflammation | Deoxycholic Acid Promotes Pyroptosis in Free Fatty Acid-Induced Steatotic Hepatocytes by Inhibiting PINK1-Mediated Mitophagy. | 2021 | Details |
| A01645 | 34670042 | N Engl J Med | A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH. | 2021 | Details |
| A01649 | 34668765 | J Med Food | Ameliorative Effect of Myricetin on Nonalcoholic Fatty Liver Disease in ob/ob Mice. | 2021 | Details |
| A01657 | 34665236 | J Mol Cell Biol | cGAS‒STING signaling and function in metabolism and kidney diseases. | 2021 | Details |
| A01665 | 34662732 | Environ Toxicol Pharmacol | Deciphering the toxicological role of Porphyromonas gingivalis derived endotoxins in liver diseases. | 2021 | Details |
| A01681 | 34656648 | Metabolism | CC chemokine ligand 3 deficiency ameliorates diet-induced steatohepatitis by regulating liver macrophage recruitment and M1/M2 status in mice. | 2021 | Details |
| A01696 | 34651580 | J Clin Invest | Sparcl1 promotes nonalcoholic steatohepatitis progression in mice through upregulation of CCL2. | 2021 | Details |
| A01697 | 34651578 | J Clin Invest | Targeting adipose tissue to tackle NASH: SPARCL1 as an emerging player. | 2021 | Details |
| A01704 | 34649337 | Biomed Pharmacother | Jiangzhi Granule attenuates non-alcoholic steatohepatitis by suppressing TNF/NFκB signaling pathway-a study based on network pharmacology. | 2021 | Details |
| A01706 | 34649219 | Biomed Pharmacother | Foresight regarding drug candidates acting on the succinate-GPR91 signalling pathway for non-alcoholic steatohepatitis (NASH) treatment. | 2021 | Details |
| A01723 | 34638941 | Int J Mol Sci | MERTK+/hi M2c Macrophages Induced by Baicalin Alleviate Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01733 | 34633706 | Hepatology | Gut microbiome features associated with liver fibrosis in Hispanics, a population at high risk for fatty liver disease. | 2021 | Details |
| A01737 | 34632357 | J Transl Autoimmun | Programmed cell death-1 rs11568821 and interleukin-28B rs12979860 polymorphisms in autoimmune hepatitis. | 2021 | Details |
| A01759 | 34627751 | Am J Pathol | Hepatic Steatosis in the Mouse Model of Wilson Disease Coincides with a Muted Inflammatory Response. | 2021 | Details |
| A01762 | 34626855 | Mol Metab | The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis. | 2021 | Details |
| A01768 | 34624333 | J Lipid Res | Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet. | 2021 | Details |
| A01773 | 34622006 | JGH Open | Effect of 48-week pemafibrate on non-alcoholic fatty liver disease with hypertriglyceridemia, as evaluated by the FibroScan-aspartate aminotransferase score. | 2021 | Details |
| A01785 | 34618982 | FASEB J | Omega-3 carboxylic acids and fenofibrate differentially alter plasma lipid mediators in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A01790 | 34617180 | Bull Exp Biol Med | Taurine Reduces Liver Damage in Non-Alcoholic Fatty Liver Disease Model in Rats by Down-Regulating IL-9 and Tumor Growth Factor TGF-β. | 2021 | Details |
| A01809 | 34607067 | Clin Res Hepatol Gastroenterol | Efficacy of statins in treatment and development of non-alcoholic fatty liver disease and steatohepatitis: A systematic review and meta-analysis. | 2021 | Details |
| A01816 | 34606532 | Food Funct | Beneficial impacts of fermented celery (Apium graveolens L.) juice on obesity prevention and gut microbiota modulation in high-fat diet fed mice. | 2021 | Details |
| A01818 | 34604973 | Eur Rev Med Pharmacol Sci | Multifaceted pathogenesis of liver steatosis in inflammatory bowel disease: a systematic review. | 2021 | Details |
| A01830 | 34602072 | Lipids Health Dis | Metabolic dysfunction associated fatty liver disease and coronavirus disease 2019: clinical relationship and current management. | 2021 | Details |
| A01833 | 34601002 | Mol Cell Endocrinol | Patchouli alcohol ameliorates skeletal muscle insulin resistance and NAFLD via AMPK/SIRT1-mediated suppression of inflammation. | 2021 | Details |
| A01837 | 34599938 | Life Sci | Curcumin activation of nuclear factor E2-related factor 2 gene (Nrf2): Prophylactic and therapeutic effect in nonalcoholic steatohepatitis (NASH). | 2021 | Details |
| A01843 | 34593018 | BMC Pharmacol Toxicol | Saroglitazar improved hepatic steatosis and fibrosis by modulating inflammatory cytokines and adiponectin in an animal model of non-alcoholic steatohepatitis. | 2021 | Details |
| A01844 | 34592488 | Phytomedicine | Activation of AMPK by triptolide alleviates nonalcoholic fatty liver disease by improving hepatic lipid metabolism, inflammation and fibrosis. | 2021 | Details |
| A01846 | 34591986 | Hepatology | OTUB1 alleviates NASH through inhibition of the TRAF6-ASK1 signaling pathways. | 2021 | Details |
| A01847 | 34591699 | J Med Food | Artichoke Extract Directly Suppresses Inflammation and Apoptosis in Hepatocytes During the Development of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01851 | 34589520 | Front Mol Biosci | Saliva and Plasma Reflect Metabolism Altered by Diabetes and Periodontitis. | 2021 | Details |
| A01860 | 34585892 | J Assoc Physicians India | Management of Hyperglycemia in COVID-19 and Post-COVID-19 Syndrome - Proposed Guidelines for India. | 2021 | Details |
| A01863 | 34584580 | Prz Gastroenterol | Association of non-alcoholic fatty liver disease with coronary artery calcification progression: a systematic review and meta-analysis. | 2021 | Details |
| A01875 | 34576229 | Int J Mol Sci | Methyl Brevifolincarboxylate Attenuates Free Fatty Acid-Induced Lipid Metabolism and Inflammation in Hepatocytes through AMPK/NF-κB Signaling Pathway. | 2021 | Details |
| A01876 | 34576136 | Int J Mol Sci | Sex Dimorphism of Nonalcoholic Fatty Liver Disease (NAFLD) in Pparg-Null Mice. | 2021 | Details |
| A01878 | 34576053 | Int J Mol Sci | Anti-Inflammatory Effect of Muscle-Derived Interleukin-6 and Its Involvement in Lipid Metabolism. | 2021 | Details |
| A01879 | 34575934 | Int J Mol Sci | The Anti-Atherosclerotic Action of FFAR4 Agonist TUG-891 in ApoE-Knockout Mice Is Associated with Increased Macrophage Polarization towards M2 Phenotype. | 2021 | Details |
| A01882 | 34574082 | Foods | AGL9: A Novel Hepatoprotective Peptide from the Larvae of Edible Insects Alleviates Obesity-Induced Hepatic Inflammation by Regulating AMPK/Nrf2 Signaling. | 2021 | Details |
| A01901 | 34566670 | Front Physiol | Gardenoside Hinders Caspase-1-Mediated Hepatocyte Pyroptosis Through the CTCF/DPP4 Signaling Pathway. | 2021 | Details |
| A01907 | 34565410 | Malar J | Transcriptome-based analysis of blood samples reveals elevation of DNA damage response, neutrophil degranulation, cancer and neurodegenerative pathways in Plasmodium falciparum patients. | 2021 | Details |
| A01909 | 34565074 | Rev Cardiovasc Med | Pathophysiological mechanisms and clinical evidence of relationship between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease. | 2021 | Details |
| A01912 | 34564899 | J Intern Med | Inflammatory and fibrotic mechanisms in NAFLD-Implications for new treatment strategies. | 2021 | Details |
| A01915 | 34564157 | Mar Drugs | Dieckol Decreases Caloric Intake and Attenuates Nonalcoholic Fatty Liver Disease and Hepatic Lymphatic Vessel Dysfunction in High-Fat-Diet-Fed Mice. | 2021 | Details |
| A01921 | 34561722 | Eur J Nutr | Effects of β-glucan, probiotics, and synbiotics on obesity-associated colitis and hepatic manifestations in C57BL/6J mice. | 2021 | Details |
| A01928 | 34559251 | Arch Toxicol | Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation. | 2021 | Details |
| A01934 | 34558849 | Hepatol Commun | Distinct Hepatic Gene-Expression Patterns of NAFLD in Patients With Obesity. | 2021 | Details |
| A01945 | 34557498 | Front Med (Lausanne) | Fecal Microbiota Transplantation as a Tool for Therapeutic Modulation of Non-gastrointestinal Disorders. | 2021 | Details |
| A01950 | 34556715 | Sci Rep | Ruminant fat intake improves gut microbiota, serum inflammatory parameter and fatty acid profile in tissues of Wistar rats. | 2021 | Details |
| A01955 | 34555255 | Liver Int | COVID-19, adaptative immune response and metabolic-associated liver disease. | 2021 | Details |
| A01962 | 34551612 | Future Med Chem | Xanthohumol alleviates T2DM-induced liver steatosis and fibrosis by mediating the NRF2/RAGE/NF-κB signaling pathway. | 2021 | Details |
| A01969 | 34548598 | Sci Rep | Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis. | 2021 | Details |
| A01973 | 34546515 | Obes Surg | Changes in Total Homocysteine and Glutathione Levels After Laparoscopic Sleeve Gastrectomy in Children with Metabolic-Associated Fatty Liver Disease. | 2021 | Details |
| A01977 | 34543756 | Clin Res Hepatol Gastroenterol | Adipose tissue dysfunction and MAFLD in obesity on the scene of COVID-19. | 2021 | Details |
| A01980 | 34543583 | Arch Physiol Biochem | Dipeptedyl peptidase-4 (DPP-4) inhibitor downregulates HMGB1/TLR4/NF-κB signaling pathway in a diabetic rat model of non-alcoholic fatty liver disease. | 2021 | Details |
| A01992 | 34536498 | Life Sci | Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway. | 2021 | Details |
| A01993 | 34536264 | Anat Rec (Hoboken) | Network pharmacology-based investigation to explore the effect and mechanism of Erchen decoction against the nonalcoholic fatty liver disease. | 2021 | Details |
| A01998 | 34534913 | Redox Biol | Hepatic Regulator of G Protein Signaling 6 (RGS6) drives non-alcoholic fatty liver disease by promoting oxidative stress and ATM-dependent cell death. | 2021 | Details |