Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A10150 | 31467918 | Biomed Res Int | Abdominal Obesity as a Predictive Factor of Nonalcoholic Fatty Liver Disease Assessed by Ultrasonography and Transient Elastography in Polycystic Ovary Syndrome and Healthy Women. | 2019 | Details |
| A10156 | 31465069 | Lab Chip | A microfluidic patterned model of non-alcoholic fatty liver disease: applications to disease progression and zonation. | 2019 | Details |
| A10157 | 31464788 | Eur J Gastroenterol Hepatol | The performance of M and XL probes of FibroScan for the diagnosis of steatosis and fibrosis on a Brazilian nonalcoholic fatty liver disease cohort. | 2020 | Details |
| A10160 | 31464779 | Eur J Gastroenterol Hepatol | Performance of noninvasive scores for the diagnosis of advanced liver fibrosis in morbidly obese with nonalcoholic fatty liver disease. | 2020 | Details |
| A10161 | 31464743 | Am J Gastroenterol | Patients With Nonalcoholic Steatohepatitis Experience Severe Impairment of Health-Related Quality of Life. | 2019 | Details |
| A10162 | 31464113 | Korean J Radiol | Quantitative Imaging in Pediatric Hepatobiliary Disease. | 2019 | Details |
| A10167 | 31460789 | Am J Physiol Gastrointest Liver Physiol | Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis. | 2019 | Details |
| A10168 | 31460584 | Arq Gastroenterol | N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL. | 2019 | Details |
| A10173 | 31454802 | Lifestyle Genom | Four-Week Omega-3 Supplementation in Carriers of the Prosteatotic PNPLA3 p.I148M Genetic Variant: An Open-Label Study. | 2019 | Details |
| A10182 | 31446562 | Obes Surg | Intraoperative Liver Biopsy During Adolescent Bariatric Surgery: Is It Really Necessary? | 2020 | Details |
| A10186 | 31444465 | Eur J Clin Nutr | Vitamin D deficiency: prevalence and association with liver disease severity in pediatric nonalcoholic fatty liver disease. | 2019 | Details |
| A10187 | 31443090 | J Physiol Pharmacol | Omentin, vaspin and irisin in chronic liver diseases. | 2019 | Details |
| A10189 | 31442319 | Hepatology | Lean NAFLD: A Distinct Entity Shaped by Differential Metabolic Adaptation. | 2020 | Details |
| A10190 | 31442254 | PLoS One | Mouse models of hereditary hemochromatosis do not develop early liver fibrosis in response to a high fat diet. | 2019 | Details |
| A10191 | 31441967 | Clin Transplant | A review of the use of transient elastography in the assessment of fibrosis and steatosis in the post-liver transplant patient. | 2019 | Details |
| A10194 | 31439237 | Eur J Radiol | Quantification of steatosis in alcoholic and nonalcoholic fatty liver disease: Evaluation of four MR techniques versus biopsy. | 2019 | Details |
| A10198 | 31437454 | Gastrointest Endosc | EUS-guided core liver biopsy sampling using a 22-gauge fork-tip needle: a prospective blinded trial for histologic and lipidomic evaluation in nonalcoholic fatty liver disease. | 2019 | Details |
| A10201 | 31436362 | Liver Int | Plasma N-terminal propeptide of type III procollagen accurately predicts liver fibrosis severity in children with non-alcoholic fatty liver disease. | 2019 | Details |
| A10203 | 31435171 | World J Gastroenterol | Reduced lysosomal acid lipase activity: A new marker of liver disease severity across the clinical continuum of non-alcoholic fatty liver disease? | 2019 | Details |
| A10204 | 31434683 | Postgrad Med J | Effect of vitamin E in non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomised controlled trials. | 2019 | Details |
| A10205 | 31433301 | J Hepatol | Integrin β1-enriched extracellular vesicles mediate monocyte adhesion and promote liver inflammation in murine NASH. | 2019 | Details |
| A10206 | 31433263 | Nutr Cancer | Serum Nutritional Markers as Prognostic Factors for Hepatic and Extrahepatic Carcinogenesis in Japanese Patients with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10208 | 31432447 | Hepatol Int | Association of epicardial adipose tissue with non-alcoholic fatty liver disease: a meta-analysis. | 2019 | Details |
| A10213 | 31430314 | PLoS One | Non-invasive assessment of portal hypertension by multi-parametric magnetic resonance imaging of the spleen: A proof of concept study. | 2019 | Details |
| A10221 | 31423319 | BMJ Open Gastroenterol | High potency multistrain probiotic improves liver histology in non-alcoholic fatty liver disease (NAFLD): a randomised, double-blind, proof of concept study. | 2019 | Details |
| A10222 | 31422872 | Trends Endocrinol Metab | Are Lifestyle Therapies Effective for NAFLD Treatment? | 2019 | Details |
| A10225 | 31422033 | Clin Res Hepatol Gastroenterol | Simple blood fibrosis tests reduce unnecessary referrals for specialized evaluations of liver fibrosis in NAFLD and ALD patients. | 2019 | Details |
| A10226 | 31421545 | Int Immunopharmacol | Scoparone alleviates inflammation, apoptosis and fibrosis of non-alcoholic steatohepatitis by suppressing the TLR4/NF-κB signaling pathway in mice. | 2019 | Details |
| A10227 | 31421115 | Chem Biol Interact | Acanthoic acid modulates lipogenesis in nonalcoholic fatty liver disease via FXR/LXRs-dependent manner. | 2019 | Details |
| A10229 | 31420528 | J Pharmacol Exp Ther | Withaferin A Improves Nonalcoholic Steatohepatitis in Mice. | 2019 | Details |
| A10231 | 31419571 | Clin Gastroenterol Hepatol | Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10236 | 31419372 | Liver Int | Procoagulant imbalance influences cardiovascular and liver damage in chronic hepatitis C independently of steatosis. | 2019 | Details |
| A10238 | 31418344 | Curr Vasc Pharmacol | What Does the Future Hold for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis? | 2019 | Details |
| A10240 | 31415794 | Mol Cell Endocrinol | Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH). | 2019 | Details |
| A10245 | 31413528 | World J Gastroenterol | Hepatocellular carcinoma in the post-hepatitis C virus era: Should we change the paradigm? | 2019 | Details |
| A10253 | 31410151 | Exp Ther Med | Association between abdominal obesity and liver steatosis and fibrosis among patients with chronic hepatitis B measured by Fibroscan. | 2019 | Details |
| A10256 | 31409057 | Cells | iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation. | 2019 | Details |
| A10265 | 31406138 | Sci Rep | TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor. | 2019 | Details |
| A10276 | 31402538 | Liver Int | CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients. | 2019 | Details |
| A10278 | 31402248 | Transplant Proc | The Utility of Noninvasive Scoring Systems for Prediction of Hepatic Steatosis in Liver Transplantation Donor Candidates. | 2019 | Details |
| A10280 | 31401389 | Cell Calcium | Deranged hepatocyte intracellular Ca2+ homeostasis and the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma. | 2019 | Details |
| A10291 | 31397685 | Clin Transl Gastroenterol | Multicenter Validation Study of a Diagnostic Algorithm to Detect NASH and Fibrosis in NAFLD Patients With Low NAFLD Fibrosis Score or Liver Stiffness. | 2019 | Details |
| A10296 | 31394730 | Cells | Current Status in Testing for Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH). | 2019 | Details |
| A10299 | 31393851 | J Clin Invest | Degradation of splicing factor SRSF3 contributes to progressive liver disease. | 2019 | Details |
| A10302 | 31393374 | Medicine (Baltimore) | Analysis of human leukocyte antigen allele polymorphism in patients with non alcoholic fatty liver disease. | 2019 | Details |
| A10303 | 31392821 | Liver Int | Lysosomal acid lipase activity and liver fibrosis in the clinical continuum of non-alcoholic fatty liver disease. | 2019 | Details |
| A10305 | 31391806 | Gastroenterol Hepatol (N Y) | Screening for Nonalcoholic Fatty Liver Disease in the Primary Care Clinic. | 2019 | Details |
| A10307 | 31391764 | World J Gastroenterol | Role of sodium-glucose co-transporter-2 inhibitors in the management of nonalcoholic fatty liver disease. | 2019 | Details |
| A10311 | 31390281 | J Med Food | Elucidation of the Metabolic and Transcriptional Responses of an Oriental Herbal Medicine, Bangpungtongseong-san, to Nonalcoholic Fatty Liver Disease in Diet-Induced Obese Mice. | 2019 | Details |
| A10316 | 31388695 | Diabetologia | Genetic inactivation of the LIGHT (TNFSF14) cytokine in mice restores glucose homeostasis and diminishes hepatic steatosis. | 2019 | Details |
| A10317 | 31388628 | Hepatol Commun | Body Composition and Genetic Lipodystrophy Risk Score Associate With Nonalcoholic Fatty Liver Disease and Liver Fibrosis. | 2019 | Details |
| A10319 | 31388626 | Hepatol Commun | Mortality Risk Detected by Atherosclerotic Cardiovascular Disease Score in Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10320 | 31388625 | Hepatol Commun | Liver Proliferation Is an Essential Driver of Fibrosis in Mouse Models of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10326 | 31387260 | Antioxidants (Basel) | Inhibition of Heme Oxygenase Antioxidant Activity Exacerbates Hepatic Steatosis and Fibrosis In Vitro. | 2019 | Details |
| A10342 | 31382287 | Ann Intern Med | How Would You Manage This Patient With Nonalcoholic Fatty Liver Disease?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. | 2019 | Details |
| A10345 | 31380833 | J Vis Exp | Inducing and Characterizing Vesicular Steatosis in Differentiated HepaRG Cells. | 2019 | Details |
| A10348 | 31380156 | Curr Hepatol Rep | Pathogenesis of NASH: The Impact of Multiple Pathways. | 2018 | Details |
| A10353 | 31378982 | Hepatology | Ammonia Scavenging Prevents Progression of Fibrosis in Experimental Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10356 | 31377187 | Nutr Metab Cardiovasc Dis | PNPLA3 gene polymorphism in Brazilian patients with type 2 diabetes: A prognostic marker beyond liver disease? | 2019 | Details |
| A10358 | 31375753 | Sci Rep | A Randomised Controlled Trial on the Effectiveness and Adherence of Modified Alternate-day Calorie Restriction in Improving Activity of Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10359 | 31375359 | Mol Ther | A Mitochondrial VDAC1-Based Peptide Greatly Suppresses Steatosis and NASH-Associated Pathologies in a Mouse Model. | 2019 | Details |
| A10360 | 31375010 | Int J Environ Res Public Health | Novel Insights into the Genetic Landscape of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10361 | 31374969 | Nutrients | Melon GliSODin® Prevents Diet-Induced NASH Onset by Reducing Fat Synthesis and Improving Liver Function. | 2019 | Details |
| A10365 | 31373184 | J Korean Med Sci | Non-Alcoholic Fatty Liver Disease and Its Association with Depression in Korean General Population. | 2019 | Details |
| A10366 | 31372873 | Obes Surg | Laparoscopic Sleeve Gastrectomy on the Horizon as a Promising Treatment Modality for NAFLD. | 2020 | Details |
| A10371 | 31369716 | J Dent Res | Oral Diseases Associated with Nonalcoholic Fatty Liver Disease in the United States. | 2019 | Details |
| A10372 | 31369606 | PLoS One | Increasing metabolic co-morbidities are associated with higher risk of advanced fibrosis in nonalcoholic steatohepatitis. | 2019 | Details |
| A10376 | 31366800 | Intern Med | Immunoglobulin G4-related Liver Disease Overlapping with Non-alcoholic Steatohepatitis That Was Diagnosed Simultaneously with Autoimmune Pancreatitis: A Case Report and Review of the Literature. | 2019 | Details |
| A10380 | 31363910 | Hepatol Int | Reversal of NASH fibrosis with pharmacotherapy. | 2019 | Details |
| A10383 | 31361543 | Am J Physiol Endocrinol Metab | eNOS deletion impairs mitochondrial quality control and exacerbates Western diet-induced NASH. | 2019 | Details |
| A10393 | 31357755 | Zhonghua Gan Zang Bing Za Zhi | [Machanism and intervention of nonalcoholic steatohepatitis-associated fibrosis]. | 2019 | Details |
| A10398 | 31355279 | Biomed Res Int | Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat. | 2019 | Details |
| A10402 | 31353118 | J Formos Med Assoc | Higher NAFLD fibrosis score is associated with impaired eGFR. | 2019 | Details |
| A10403 | 31352173 | Cytokine | Chemokine ligand 20 (CCL20) expression increases with NAFLD stage and hepatic stellate cell activation and is regulated by miR-590-5p. | 2019 | Details |
| A10405 | 31352092 | Clin Gastroenterol Hepatol | Clinically Significant Fibrosis Is Associated With Longitudinal Increases in Fibrosis-4 and Nonalcoholic Fatty Liver Disease Fibrosis Scores. | 2019 | Details |
| A10406 | 31351021 | Diabetes Metab Res Rev | C-peptide is associated with NAFLD inflammatory and fibrotic progression in type 2 diabetes. | 2019 | Details |
| A10409 | 31348282 | Medicine (Baltimore) | Association between red cell distribution width-to-platelet ratio and hepatic fibrosis in nonalcoholic fatty liver disease: A cross-sectional study. | 2019 | Details |
| A10414 | 31345776 | Lancet Diabetes Endocrinol | Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study. | 2019 | Details |
| A10415 | 31345163 | BMC Gastroenterol | Curcumin and inflammation in non-alcoholic fatty liver disease: a randomized, placebo controlled clinical trial. | 2019 | Details |
| A10423 | 31342533 | Aliment Pharmacol Ther | Improvement of non-invasive markers of NAFLD from an individualised, web-based exercise program. | 2019 | Details |
| A10426 | 31341444 | Integr Med (Encinitas) | Non-Alcoholic Fatty Liver Disease, an Overview. | 2019 | Details |
| A10433 | 31337855 | Sci Rep | Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma. | 2019 | Details |
| A10434 | 31337151 | Int J Mol Sci | The Number of Liver Galectin-3 Positive Cells Is Dually Correlated with NAFLD Severity in Children. | 2019 | Details |
| A10436 | 31336557 | Diabetes Metab Syndr | Effect of diet-induced weight loss on cytokeratin-18 levels in overweight and obese patients with liver fibrosis. | 2019 | Details |
| A10448 | 31333877 | Clin Diabetes Endocrinol | Natural history of ROHHAD syndrome: development of severe insulin resistance and fatty liver disease over time. | 2019 | Details |
| A10449 | 31333307 | World J Gastroenterol | Hepatocellular carcinoma: Therapeutic advances in signaling, epigenetic and immune targets. | 2019 | Details |
| A10450 | 31332938 | Liver Int | Referral pathways for patients with NAFLD based on non-invasive fibrosis tests: Diagnostic accuracy and cost analysis. | 2019 | Details |
| A10452 | 31332029 | Diabetes Care | Role of Vitamin E for Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes: A Randomized Controlled Trial. | 2019 | Details |
| A10456 | 31330134 | Metabolism | AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease. | 2019 | Details |
| A10457 | 31328300 | Aliment Pharmacol Ther | Depression is associated with non-alcoholic fatty liver disease among adults in the United States. | 2019 | Details |
| A10458 | 31328113 | Prev Nutr Food Sci | Health Benefits of Carotenoids: A Role of Carotenoids in the Prevention of Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10460 | 31327168 | Mol Nutr Food Res | Industrial Trans Fatty Acids Stimulate SREBP2-Mediated Cholesterogenesis and Promote Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10465 | 31325638 | Biochim Biophys Acta Mol Cell Biol Lipids | Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH. | 2019 | Details |
| A10469 | 31324181 | Nutr J | The effect of total anthocyanin-base standardized (Cornus mas L.) fruit extract on liver function, tumor necrosis factor α, malondealdehyde, and adiponectin in patients with non-alcoholic fatty liver: a study protocol for a double-blind randomized clinical trial. | 2019 | Details |
| A10471 | 31323923 | Toxins (Basel) | Sub-Chronic Microcystin-LR Liver Toxicity in Preexisting Diet-Induced Nonalcoholic Steatohepatitis in Rats. | 2019 | Details |
| A10472 | 31322445 | Scand J Gastroenterol | Transient elastography: should XL probe be used in all overweight patients? | 2019 | Details |
| A10480 | 31319186 | Clin Gastroenterol Hepatol | Long-term Liver-related Outcomes of Patients With Chronic Liver Diseases in Australia. | 2019 | Details |
| A10481 | 31318914 | PLoS One | Hepatic enzyme ALT as a marker of glucose abnormality in men with cystic fibrosis. | 2019 | Details |
| A10487 | 31315327 | J Assoc Physicians India | Etiological Patterns, Liver Fibrosis Stages and Prescribing Patterns of Hepato-Protective Agents in Indian Patients with Chronic Liver Disease. | 2018 | Details |
| A10494 | 31311600 | BMC Med | GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network. | 2019 | Details |