Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A38083 | 12197781 | Altern Med Rev | Nonalcoholic fatty liver disease: relationship to insulin sensitivity and oxidative stress. Treatment approaches using vitamin E, magnesium, and betaine. | 2002 | Details |
| A38186 | 11944630 | Semin Gastrointest Dis | Diabetes mellitus, obesity, and hepatic steatosis. | 2002 | Details |
| A38220 | 11873108 | J Clin Gastroenterol | Update on nonalcoholic fatty liver disease. | 2002 | Details |
| A38236 | 11812920 | Toxicol Sci | Mechanisms of hepatotoxicity. | 2002 | Details |
| A38249 | 11766638 | Pathologe | [Alcoholic and nonalcoholic steatohepatitis. Histopathologic and pathogenetic considerations]. | 2001 | Details |
| A38294 | 11668021 | Am J Physiol Gastrointest Liver Physiol | Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress. | 2001 | Details |
| A38334 | 11522755 | Gastroenterology | Nonalcoholic steatohepatitis. | 2001 | Details |
| A38417 | 11296694 | Semin Liver Dis | Etiopathogenesis of nonalcoholic steatohepatitis. | 2001 | Details |
| A38431 | 11266382 | Gastroenterology | Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. | 2001 | Details |
| A38567 | 10913824 | Biochim Biophys Acta | Hydroperoxide specificity of plant and human tissue lipoxygenase: an in vitro evaluation using N-demethylation of phenothiazines. | 2000 | Details |
| A38621 | 10772651 | J Clin Invest | CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. | 2000 | Details |
| A38723 | 10488699 | J Hepatol | Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis. | 1999 | Details |
| A42203 | 35247253 | Aging (Albany NY) | Enhancing CISD2 expression to retard liver aging. | 2022 | Details |
| A42248 | 35104011 | FASEB J | NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury. | 2022 | Details |
| A42297 | 34935193 | Fundam Clin Pharmacol | Hepatoprotective and therapeutic effects of resveratrol: A focus on anti-inflammatory and antioxidative activities. | 2022 | Details |
| A42317 | 34887111 | Clin Investig Arterioscler | Bempedoic acid as a PPARα activator: new perspectives for hepatic steatosis treatment in a female rat experimental model. | 2021 | Details |
| A42359 | 34767670 | Biofactors | Vitamin D3 enhances the effects of omega-3 oils against metabolic dysfunction-associated fatty liver disease in rat. | 2021 | Details |
| A42388 | 34698580 | Crit Rev Food Sci Nutr | Effect of kombucha intake on the gut microbiota and obesity-related comorbidities: A systematic review. | 2021 | Details |
| A42403 | 34630116 | Front Pharmacol | An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism. | 2021 | Details |
| A42422 | 34572325 | Biomedicines | Glycomacropeptide for Management of Insulin Resistance and Liver Metabolic Perturbations. | 2021 | Details |
| A42452 | 34503598 | J Dev Orig Health Dis | Metabolic programming in offspring of mice fed fructose during pregnancy and lactation. | 2021 | Details |
| A42469 | 34455076 | Pharmacol Res | The pivotal role of Nrf2 activators in adipocyte biology. | 2021 | Details |
| A42480 | 34425095 | Gastroenterology | Hepatic miR-144 Drives Fumarase Activity Preventing NRF2 Activation During Obesity. | 2021 | Details |
| A42497 | 34373772 | Oxid Med Cell Longev | Corrigendum to "Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease". | 2021 | Details |
| A42654 | 33869980 | J Endocr Soc | Removal of Epididymal Visceral Adipose Tissue Prevents Obesity-Induced Multi-organ Insulin Resistance in Male Mice. | 2021 | Details |
| A42663 | 33856704 | J Periodontol | Food restriction reduces hepatic alterations associated with experimental periodontitis. | 2021 | Details |
| A42706 | 33693864 | J Nutr | Milk Fat Globule Membrane Supplementation During Suckling Ameliorates Maternal High Fat Diet-Induced Hepatic Steatosis in Adult Male Offspring of Mice. | 2021 | Details |
| A42735 | 33604316 | Can J Gastroenterol Hepatol | A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma. | 2021 | Details |
| A42799 | 33445170 | J Clin Invest | Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer. | 2021 | Details |
| A42817 | 33355004 | Crit Rev Food Sci Nutr | Interaction between iron and omega-3 fatty acids metabolisms: where is the cross-link? | 2020 | Details |
| A42849 | 33297754 | Arterioscler Thromb Vasc Biol | The Dynamic Platelet Transcriptome in Obesity and Weight Loss. | 2020 | Details |
| A42853 | 33282605 | Cureus | Effects of Oxidant-Antioxidant and Vitamin D Levels on Clinical and Laboratory Data in Children With Fatty Liver Disease. | 2020 | Details |
| A42863 | 33259630 | Toxicol Sci | Gestational Cd Exposure in the CD-1 Mouse Induces Sex-Specific Hepatic Insulin Insensitivity, Obesity, and Metabolic Syndrome in Adult Female Offspring. | 2020 | Details |
| A42932 | 33045621 | Redox Biol | Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner. | 2020 | Details |
| A42934 | 33044023 | J Cell Physiol | Exenatide improves random-pattern skin flap survival via TFE3 mediated autophagy augment. | 2020 | Details |
| A42975 | 32914727 | Endocr Metab Immune Disord Drug Targets | Berberine as a Potential Multi-Target Agent for Metabolic Diseases: A Review of Investigations for Berberine. | 2021 | Details |
| A43009 | 32821334 | World J Hepatol | Ipragliflozin-induced improvement of liver steatosis in obese mice may involve sirtuin signaling. | 2020 | Details |
| A43059 | 32680469 | BMC Gastroenterol | Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis. | 2020 | Details |
| A43060 | 32668973 | Am J Chin Med | Gastrodin Pretreatment Protects Liver Against Ischemia-Reperfusion Injury via Activation of the Nrf2/HO-1 Pathway. | 2020 | Details |
| A43094 | 32586106 | Antioxid Redox Signal | Phospholipase D as a Potential Modulator of Metabolic Syndrome: Impact of Functional Foods. | 2020 | Details |
| A43099 | 32571642 | Free Radic Biol Med | Corrigendum to "Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease" [Free Radic. Biol. Med. 152 (2020) 116-141]. | 2020 | Details |
| A43107 | 32553811 | Eur J Pharmacol | The effect of emodin on liver disease -- comprehensive advances in molecular mechanisms. | 2020 | Details |
| A43108 | 32549999 | Clin Hypertens | Uric acid and cardiometabolic diseases. | 2020 | Details |
| A43111 | 32532017 | Int J Mol Sci | Genomic and Non-Genomic Mechanisms of Action of Thyroid Hormones and Their Catabolite 3,5-Diiodo-L-Thyronine in Mammals. | 2020 | Details |
| A43192 | 32338040 | Antioxid Redox Signal | Glycomacropeptide: A Bioactive Milk Derivative to Alleviate Metabolic Syndrome Outcomes. | 2020 | Details |
| A43230 | 32229664 | J Basic Clin Physiol Pharmacol | Altered composition of high-lipid diet may generate reactive oxygen species by disturbing the balance of antioxidant and free radicals. | 2020 | Details |
| A43277 | 32086945 | Hepatology | Elevated Fructose and Uric Acid Through Aldose Reductase Contribute to Experimental and Human Alcoholic Liver Disease. | 2020 | Details |
| A43287 | 32061110 | J Pineal Res | Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies. | 2020 | Details |
| A43307 | 32012270 | J Cell Physiol | Effects of different fatty acids on BRL3A rat liver cell damage. | 2020 | Details |
| A43400 | 31823402 | J Food Biochem | Comparative effects of nanoemulsions loaded with duck oil and lard oil on palmitate-induced lipotoxicity. | 2019 | Details |
| A43430 | 31737070 | Int J Endocrinol | Effects of Uric Acid on Diabetes Mellitus and Its Chronic Complications. | 2019 | Details |
| A43460 | 31663469 | Curr Med Chem | Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids. | 2021 | Details |
| A43468 | 31649547 | Front Pharmacol | Mitophagy in Hepatic Insulin Resistance: Therapeutic Potential and Concerns. | 2019 | Details |
| A43501 | 31576541 | Adv Exp Med Biol | Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis. | 2019 | Details |
| A43537 | 31475778 | J Cell Mol Med | Protective role of melatonin in early-stage and end-stage liver cirrhosis. | 2019 | Details |
| A43573 | 31378113 | J Int Med Res | Tanshinone IIA ameliorates non-alcoholic fatty liver disease through targeting peroxisome proliferator-activated receptor gamma and toll-like receptor 4. | 2019 | Details |
| A43582 | 31355732 | Zebrafish | Palmitic Acid-Enriched Diet Induces Hepatic Steatosis and Injury in Adult Zebrafish. | 2019 | Details |
| A43587 | 31345023 | J Agric Food Chem | Processed Meat Protein Promoted Inflammation and Hepatic Lipogenesis by Upregulating Nrf2/Keap1 Signaling Pathway in Glrx-Deficient Mice. | 2019 | Details |
| A43623 | 31264285 | J Cell Biochem | Effect of oleic acid on induction of steatosis and cytotoxicity in BRL 3A cells. | 2019 | Details |
| A43636 | 31240235 | Hypoxia (Auckl) | Role of pseudohypoxia in the pathogenesis of type 2 diabetes. | 2019 | Details |
| A43660 | 31162673 | Alcohol Clin Exp Res | Chalcone Derivative L6H21 Reduces EtOH + LPS-Induced Liver Injury Through Inhibition of NLRP3 Inflammasome Activation. | 2019 | Details |
| A43683 | 31106419 | J Cell Physiol | Impact of different ectopic fat depots on cardiovascular and metabolic diseases. | 2019 | Details |
| A43749 | 30968034 | World J Clin Cases | Effects of apoptosis on liver aging. | 2019 | Details |
| A43752 | 30958566 | Hepatology | A Tale of Two Complications of Obesity: NASH and Hepatocellular Carcinoma. | 2019 | Details |
| A43816 | 30805080 | Oxid Med Cell Longev | Hydrogen Sulfide as a Novel Regulatory Factor in Liver Health and Disease. | 2019 | Details |
| A43846 | 30705513 | J Clin Biochem Nutr | 5-Aminolevulinic acid with ferrous iron improves early renal damage and hepatic steatosis in high fat diet-induced obese mice. | 2018 | Details |
| A43946 | 30379115 | Rejuvenation Res | Rosmarinic Acid Ameliorates H2O2-Induced Oxidative Stress in L02 Cells Through MAPK and Nrf2 Pathways. | 2018 | Details |
| A44001 | 30174510 | Saudi J Biol Sci | Effects of a medicinal plant Macrotyloma uniflorum (Lam.) Verdc.formulation (MUF) on obesity-associated oxidative stress-induced liver injury. | 2018 | Details |
| A44032 | 30080294 | Phytother Res | Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases. | 2018 | Details |
| A44034 | 30078211 | J Cell Physiol | Cellular senescence: Molecular mechanisms and pathogenicity. | 2018 | Details |
| A44059 | 30014902 | Redox Biol | Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway. | 2018 | Details |
| A44069 | 29967757 | PeerJ | Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study. | 2018 | Details |
| A44148 | 29578867 | Eur J Gastroenterol Hepatol | The relationship between urinary genistein levels and serum alanine aminotransferase levels in adults in the USA: National Health and Nutrition Examination Survey 1999-2010. | 2018 | Details |
| A44246 | 29254277 | Oncotarget | Apoptosis in the aging liver. | 2017 | Details |
| A44255 | 29224111 | Adv Exp Med Biol | Prenatal Testosterone Programming of Insulin Resistance in the Female Sheep. | 2017 | Details |
| A44290 | 29142166 | J Toxicol Sci | Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling. | 2017 | Details |
| A44292 | 29125262 | Minerva Gastroenterol Dietol | Mediterranean diet in liver steatosis: the role of polyphenols. | 2017 | Details |
| A44300 | 30838978 | Hepatol Commun | Human immunodeficiency virus and liver disease: A comprehensive update. | 2017 | Details |
| A44372 | 28795381 | Chin J Integr Med | Research progress on prevention and treatment of glucolipid metabolic disease with integrated traditional Chinese and Western medicine. | 2017 | Details |
| A44388 | 28739056 | Nutr Res | Supplementation with Vitis vinifera L. skin extract improves insulin resistance and prevents hepatic lipid accumulation and steatosis in high-fat diet-fed mice. | 2017 | Details |
| A44460 | 28552526 | Biochem Biophys Res Commun | Liver receptor homolog-1 regulates mouse superoxide dismutase 2. | 2017 | Details |
| A44505 | 28448873 | Biomed Pharmacother | Osthole attenuates lipid accumulation, regulates the expression of inflammatory mediators, and increases antioxidants in FL83B cells. | 2017 | Details |
| A44511 | 28409336 | Lipids | Dietary Docosahexaenoic Acid and trans-10, cis-12-Conjugated Linoleic Acid Differentially Alter Oxylipin Profiles in Mouse Periuterine Adipose Tissue. | 2017 | Details |
| A44593 | 28073147 | Hepatology | Treating nonalcoholic steatohepatitis in children: Not a cinch task. | 2017 | Details |
| A44612 | 27981604 | Hepatology | Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice. | 2017 | Details |
| A44623 | 27918207 | Can J Physiol Pharmacol | Gemigliptin ameliorates Western-diet-induced metabolic syndrome in mice. | 2016 | Details |
| A44667 | 27629157 | Hepatology | Hepatocellular carcinoma in nonalcoholic fatty liver disease: A link between oxidative stress and T-cell suppression. | 2016 | Details |
| A44678 | 27435327 | Dig Dis Sci | Targeting Hepatic Fibrosis in Autoimmune Hepatitis. | 2016 | Details |
| A44710 | 27635189 | Oxid Med Cell Longev | Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice. | 2016 | Details |
| A44726 | 27534992 | J Lipid Res | Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis. | 2016 | Details |
| A44730 | 27511913 | Toxicol Appl Pharmacol | Hepatocyte-protective effect of nectandrin B, a nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK phosphorylation and AMPK-dependent inhibition of GSK-3β. | 2016 | Details |
| A44731 | 27501737 | J Hepatol | Nocturnal hypoxia in obese-related obstructive sleep apnea as a putative trigger of oxidative stress in pediatric NAFLD progression. | 2016 | Details |
| A44738 | 27484935 | Aliment Pharmacol Ther | Editorial: dark chocolate may improve NAFLD and metabolic syndrome by reducing oxidative stress. | 2016 | Details |
| A44754 | 27432221 | Mol Nutr Food Res | Prolonged feeding with green tea polyphenols exacerbates cholesterol-induced fatty liver disease in mice. | 2016 | Details |
| A44804 | 27264097 | J Nutr Sci Vitaminol (Tokyo) | Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. | 2016 | Details |
| A44818 | 27189109 | Sci Rep | Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. | 2016 | Details |
| A44840 | 27108106 | Food Chem Toxicol | High calcium diet improves the liver oxidative stress and microsteatosis in adult obese rats that were overfed during lactation. | 2016 | Details |
| A44938 | 26676812 | Semin Liver Dis | Genetics of Alcoholic Liver Disease. | 2015 | Details |
| A44988 | 26515481 | J Bioenerg Biomembr | Letter to the Editor: The bioenergetics of hepatic mitochondria isolated from avocado oil-treated rats: typical experimental errors in the study of the bioenergetics of isolated mitochondria. | 2015 | Details |
| A44989 | 26515480 | J Bioenerg Biomembr | Response to the Letter to the Editor "the bioenergetics of hepatic mitochondria isolated from avocado oil-treated rats". | 2015 | Details |