Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A10501 | 31310032 | J Gastroenterol Hepatol | Comparing point shear wave elastography (ElastPQ) and transient elastography for diagnosis of fibrosis stage in non-alcoholic fatty liver disease. | 2019 | Details |
| A10505 | 31309589 | Hepatology | Nonalcoholic Steatohepatitis Is Associated With Liver-Related Outcomes and All-Cause Mortality in Chronic Hepatitis B. | 2019 | Details |
| A10510 | 31308634 | Drug Des Devel Ther | The protective effect and mechanism of the FXR agonist obeticholic acid via targeting gut microbiota in non-alcoholic fatty liver disease. | 2019 | Details |
| A10513 | 31307925 | Obes Res Clin Pract | Nonalcoholic fatty liver disease does not predict worse perioperative outcomes in bariatric surgery. | 2019 | Details |
| A10514 | 31307592 | Adv Pharmacol | Drug-induced liver injury in obesity and nonalcoholic fatty liver disease. | 2019 | Details |
| A10516 | 31306673 | Toxicol Appl Pharmacol | Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis. | 2019 | Details |
| A10525 | 31301321 | J Hepatol | Crosstalk between adipose tissue insulin resistance and liver macrophages in non-alcoholic fatty liver disease. | 2019 | Details |
| A10528 | 31300805 | Sci Rep | Wisteria floribunda agglutinin-positive mac-2 binding protein as an age-independent fibrosis marker in nonalcoholic fatty liver disease. | 2019 | Details |
| A10531 | 31300231 | J Hepatol | Report on the AASLD/EASL joint workshop on clinical trial endpoints in NAFLD. | 2019 | Details |
| A10533 | 31299062 | PLoS One | AEBP1 expression increases with severity of fibrosis in NASH and is regulated by glucose, palmitate, and miR-372-3p. | 2019 | Details |
| A10536 | 31297627 | Dig Dis Sci | A Cholecystokinin Receptor Antagonist Halts Nonalcoholic Steatohepatitis and Prevents Hepatocellular Carcinoma. | 2019 | Details |
| A10537 | 31296161 | BMC Gastroenterol | Cost-comparison analysis of FIB-4, ELF and fibroscan in community pathways for non-alcoholic fatty liver disease. | 2019 | Details |
| A10540 | 31293912 | J Clin Transl Hepatol | Practical Use of Transient Elastography in Screening for Nonalcoholic Steatohepatitis in a Japanese Population. | 2019 | Details |
| A10545 | 31293441 | Front Physiol | The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH). | 2019 | Details |
| A10547 | 31293337 | World J Gastroenterol | Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. | 2019 | Details |
| A10550 | 31292843 | Clin J Gastroenterol | Long-term luseogliflozin therapy improves histological activity of non-alcoholic steatohepatitis accompanied by type 2 diabetes mellitus. | 2019 | Details |
| A10552 | 31292497 | Sci Rep | Development of liver surface nodularity quantification program and its clinical application in nonalcoholic fatty liver disease. | 2019 | Details |
| A10557 | 31291245 | PLoS One | Assay validation and clinical performance of chronic inflammatory and chemokine biomarkers of NASH fibrosis. | 2019 | Details |
| A10559 | 31290769 | Eur J Gastroenterol Hepatol | Arterial stiffness is associated independently with liver stiffness in biopsy-proven nonalcoholic fatty liver disease: a transient elastography study. | 2020 | Details |
| A10561 | 31290733 | J Med Food | The Effectiveness of Mediterranean Diet in Nonalcoholic Fatty Liver Disease Clinical Course: An Intervention Study. | 2019 | Details |
| A10563 | 31290072 | Hepatol Int | Relationship between relative skeletal muscle mass and nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2019 | Details |
| A10565 | 31288993 | Mol Metab | GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury. | 2019 | Details |
| A10568 | 31288283 | Z Gastroenterol | [Microbiome & NASH - partners in crime driving progression of fatty liver disease]. | 2019 | Details |
| A10569 | 31287572 | Hepatology | Report on the AASLD/EASL Joint Workshop on Clinical Trial Endpoints in NAFLD. | 2019 | Details |
| A10575 | 31283527 | Eur J Gastroenterol Hepatol | Sarcopenia assessed using bioimpedance analysis is associated independently with significant liver fibrosis in patients with chronic liver diseases. | 2020 | Details |
| A10581 | 31281067 | Dig Liver Dis | Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease. | 2019 | Details |
| A10588 | 31279902 | J Hepatol | The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysis. | 2019 | Details |
| A10589 | 31279739 | Metabolism | Laparoscopic sleeve gastrectomy reverses non-alcoholic fatty liver disease modulating oxidative stress and inflammation. | 2019 | Details |
| A10593 | 31278377 | Nat Rev Gastroenterol Hepatol | NAFLD in children: new genes, new diagnostic modalities and new drugs. | 2019 | Details |
| A10594 | 31278269 | Nat Commun | Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy. | 2019 | Details |
| A10598 | 31275584 | BMJ Open Gastroenterol | Aspartate transaminase to platelet ratio index (APRI) but not FIB-5 or FIB-4 is accurate in ruling out significant fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) in an urban slum-dwelling population. | 2019 | Details |
| A10601 | 31275407 | Evid Based Complement Alternat Med | Pharmacological Activities of Alisma orientale against Nonalcoholic Fatty Liver Disease and Metabolic Syndrome: Literature Review. | 2019 | Details |
| A10603 | 31274677 | J Am Assoc Nurse Pract | Readiness for the epidemic: The adult nonalcoholic fatty liver disease toolkit for primary care nurse practitioners. | 2020 | Details |
| A10604 | 31274482 | Asian J Androl | Histologically proven hepatic steatosis associates with lower testosterone levels in men with obesity. | 2021 | Details |
| A10605 | 31273855 | Phytother Res | Puerarin protects against high-fat high-sucrose diet-induced non-alcoholic fatty liver disease by modulating PARP-1/PI3K/AKT signaling pathway and facilitating mitochondrial homeostasis. | 2019 | Details |
| A10607 | 31273617 | Hepatol Int | Hepatology through the crystal ball. | 2019 | Details |
| A10609 | 31272248 | Scand J Gastroenterol | Transient liver elastography in normal pregnancy - a longitudinal cohort study. | 2019 | Details |
| A10610 | 31272131 | J Gastroenterol Hepatol | Association between advanced fibrosis in fatty liver disease and overall mortality based on body fat distribution. | 2019 | Details |
| A10613 | 31271665 | Hepatology | Noninvasive Tests Accurately Identify Advanced Fibrosis due to NASH: Baseline Data From the STELLAR Trials. | 2019 | Details |
| A10615 | 31270645 | Mol Cell Biochem | Apelin promotes hepatic fibrosis through ERK signaling in LX-2 cells. | 2019 | Details |
| A10624 | 31266632 | Biochem Biophys Res Commun | Expression of Vsig4 attenuates macrophage-mediated hepatic inflammation and fibrosis in high fat diet (HFD)-induced mice. | 2019 | Details |
| A10625 | 31266618 | Clin Liver Dis | The Effects of Hepatic Steatosis on the Natural History of HBV Infection. | 2019 | Details |
| A10626 | 31266306 | J Proteome Res | Quantifying Protein-Specific N-Glycome Profiles by Focused Protein and Immunoprecipitation Glycomics. | 2019 | Details |
| A10632 | 31262487 | HPB (Oxford) | Expanding the Liver Imaging Reporting and Data System (LI-RADS) v2018 diagnostic population: performance and reliability of LI-RADS for distinguishing hepatocellular carcinoma (HCC) from non-HCC primary liver carcinoma in patients who do not meet strict LI-RADS high-risk criteria. | 2019 | Details |
| A10633 | 31260793 | Contemp Clin Trials | REGENERATE: Design of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis. | 2019 | Details |
| A10637 | 31260026 | JAMA Intern Med | Association of Weight Loss Interventions With Changes in Biomarkers of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2019 | Details |
| A10638 | 31258623 | Therap Adv Gastroenterol | Insights into the evolving role of the gut microbiome in nonalcoholic fatty liver disease: rationale and prospects for therapeutic intervention. | 2019 | Details |
| A10640 | 31258138 | Turk J Gastroenterol | Growing burden of nonalcoholic fatty liver disease in Turkey: A single-center experience. | 2019 | Details |
| A10641 | 31258135 | Turk J Gastroenterol | Non-alcoholic fatty liver disease: A growing public health problem in Turkey. | 2019 | Details |
| A10647 | 31255652 | Gastroenterology | Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10651 | 31254236 | Clin Rheumatol | Metabolic syndrome, non-alcoholic fatty liver disease and liver stiffness in psoriatic arthritis and psoriasis patients. | 2019 | Details |
| A10660 | 31250467 | Aliment Pharmacol Ther | The PNPLA3 rs738409 C>G variant influences the association between low skeletal muscle mass and NAFLD: the Shanghai Changfeng Study. | 2019 | Details |
| A10669 | 31244392 | Biosci Biotechnol Biochem | Extracts of bilberry (Vaccinium myrtillus L.) fruits improve liver steatosis and injury in mice by preventing lipid accumulation and cell death. | 2019 | Details |
| A10671 | 31243878 | J Viral Hepat | Liver steatosis is a major predictor of poor outcomes in chronic hepatitis C patients with sustained virological response. | 2019 | Details |
| A10675 | 31241693 | Rev Paul Pediatr | PREVALENCE OF HEPATIC STEATOSIS AMONG CHILDREN AND ADOLESCENTS WITH CYSTIC FIBROSIS AND ITS ASSOCIATION WITH NUTRITIONAL STATUS. | 2019 | Details |
| A10678 | 31239664 | Int J Nanomedicine | Mixed micelles loaded with the 5-benzylidenethiazolidine-2,4-dione derivative SKLB023 for efficient treatment of non-alcoholic steatohepatitis. | 2019 | Details |
| A10688 | 31235168 | Diabetes Metab Syndr | Efficacy of a non-invasive model in predicting the cardiovascular morbidity and histological severity in non-alcoholic fatty liver disease. | 2019 | Details |
| A10690 | 31235161 | Diabetes Metab Syndr | Serum Ferritin level, microalbuminuria and non-alcoholic fatty liver disease in type 2 diabetic patients. | 2019 | Details |
| A10697 | 31233672 | Eur J Neurol | Favorable impact of non-alcoholic fatty liver disease on the cerebral white matter hyperintensity in a neurologically healthy population. | 2019 | Details |
| A10700 | 31232044 | Clin Lab | Association between Serum Ferritin Level and Nonalcoholic Fatty Liver Disease in a Non-Obese Chinese Population: a Cross-Sectional Study. | 2019 | Details |
| A10701 | 31230380 | Hepatology | The Role of Senescence in the Development of Nonalcoholic Fatty Liver Disease and Progression to Nonalcoholic Steatohepatitis. | 2019 | Details |
| A10705 | 31228640 | Prog Neuropsychopharmacol Biol Psychiatry | Cannabis consumption and non-alcoholic fatty liver disease. A three years longitudinal study in first episode non-affective psychosis patients. | 2019 | Details |
| A10711 | 31226595 | J Hazard Mater | Chronic exposure to tetrabromodiphenyl ether (BDE-47) aggravates hepatic steatosis and liver fibrosis in diet-induced obese mice. | 2019 | Details |
| A10713 | 31226232 | Liver Int | Metabolically healthy versus unhealthy obesity and risk of fibrosis progression in non-alcoholic fatty liver disease. | 2019 | Details |
| A10723 | 31221701 | Diabetes Care | Use of Plasma Fragments of Propeptides of Type III, V, and VI Procollagen for the Detection of Liver Fibrosis in Type 2 Diabetes. | 2019 | Details |
| A10729 | 31219362 | Infect Dis (Lond) | Improvement in liver steatosis after the switch from a ritonavir-boosted protease inhibitor to raltegravir in HIV-infected patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A10732 | 31217846 | Am J Transl Res | Berberine prevents non-alcoholic steatohepatitis-derived hepatocellular carcinoma by inhibiting inflammation and angiogenesis in mice. | 2019 | Details |
| A10736 | 31215672 | Hepatology | Sestrin 3 Protects Against Diet-Induced Nonalcoholic Steatohepatitis in Mice Through Suppression of Transforming Growth Factor β Signal Transduction. | 2019 | Details |
| A10753 | 31209721 | Dig Dis Sci | Performance of Controlled Attenuation Parameter in Patients with Advanced Chronic Liver Disease and Portal Hypertension. | 2019 | Details |
| A10754 | 31209199 | Cell Death Dis | Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis. | 2019 | Details |
| A10772 | 31201553 | Handb Exp Pharmacol | Pharmacologic Modulation of Bile Acid-FXR-FGF15/FGF19 Pathway for the Treatment of Nonalcoholic Steatohepatitis. | 2019 | Details |
| A10775 | 31197983 | J Korean Med Sci | Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis. | 2019 | Details |
| A10776 | 31197565 | Handb Exp Pharmacol | Nonsteroidal FXR Ligands: Current Status and Clinical Applications. | 2019 | Details |
| A10777 | 31197470 | Acta Diabetol | Risk factors for non-alcoholic fatty liver disease-associated hepatic fibrosis in type 2 diabetes patients. | 2019 | Details |
| A10783 | 31195434 | Gut Liver | Extrahepatic Manifestations of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A10784 | 31195161 | Clin Gastroenterol Hepatol | Development and Validation of Hepamet Fibrosis Scoring System-A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease With Advanced Fibrosis. | 2019 | Details |
| A10785 | 31195117 | Biochim Biophys Acta Mol Basis Dis | Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis. | 2019 | Details |
| A10790 | 31191550 | Front Immunol | Natural Killer Cells and Type 1 Innate Lymphoid Cells Are New Actors in Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A10792 | 31191323 | Front Pharmacol | Role of Myeloid-Epithelial-Reproductive Tyrosine Kinase and Macrophage Polarization in the Progression of Atherosclerotic Lesions Associated With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10794 | 31189885 | Cell Death Dis | Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis. | 2019 | Details |
| A10796 | 31188634 | Am J Physiol Gastrointest Liver Physiol | Combination of CCl4 with alcoholic and metabolic injuries mimics human liver fibrosis. | 2019 | Details |
| A10797 | 31187872 | Folia Histochem Cytobiol | The immunoreactivity of TGF-b1 in non-alcoholic fatty liver disease. | 2019 | Details |
| A10809 | 31178295 | Med Clin (Barc) | Recommendations for the detection, diagnosis and follow-up of patients with non-alcoholic fatty liver disease in primary and hospital care. | 2019 | Details |
| A10815 | 31176297 | Eur J Endocrinol | Lean non-alcoholic fatty liver disease and development of diabetes: a cohort study. | 2019 | Details |
| A10816 | 31176163 | Biomed Pharmacother | Protective effect of genistein on nonalcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A10818 | 31175077 | Arab J Gastroenterol | Egyptian liver library: An indexed database for liver disease evidence in Egypt. | 2019 | Details |
| A10828 | 31169972 | Liver Int | Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity. | 2019 | Details |
| A10829 | 31169533 | Am J Gastroenterol | Impact of Obesity and Alanine Aminotransferase Levels on the Diagnostic Accuracy for Advanced Liver Fibrosis of Noninvasive Tools in Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10840 | 31163617 | Int J Mol Sci | Exogenous Administration of Low-Dose Lipopolysaccharide Potentiates Liver Fibrosis in a Choline-Deficient l-Amino-Acid-Defined Diet-Induced Murine Steatohepatitis Model. | 2019 | Details |
| A10841 | 31162812 | Liver Int | Nonalcoholic steatohepatitis is associated with a higher risk of advanced colorectal neoplasm. | 2019 | Details |
| A10845 | 31161349 | Eur J Nutr | Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet: possible role of higher formation of triglycerides enriched in monounsaturated fatty acids. | 2019 | Details |
| A10846 | 31160348 | Cancer Epidemiol Biomarkers Prev | Association between Liver Fibrosis and Serum PSA among U.S. Men: National Health and Nutrition Examination Survey (NHANES), 2001-2010. | 2019 | Details |
| A10850 | 31157422 | Aliment Pharmacol Ther | Long-term metformin use may improve clinical outcomes in diabetic patients with non-alcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis. | 2019 | Details |
| A10851 | 31156626 | Front Immunol | Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells. | 2019 | Details |
| A10853 | 31155826 | Liver Int | Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study. | 2019 | Details |
| A10854 | 31155687 | Dig Dis Sci | Low Free Triiodothyronine Is Associated with Advanced Fibrosis in Patients at High Risk for Nonalcoholic Steatohepatitis. | 2019 | Details |
| A10855 | 31155606 | Exp Anim | Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM mice. | 2019 | Details |
| A10856 | 31153716 | Ultrasound Med Biol | The Speed of Sound in Rat Liver With Steatohepatitis: Ex Vivo Analysis Using Two Types of Ultrasound Systems. | 2019 | Details |
| A10860 | 31152791 | Free Radic Biol Med | Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease. | 2019 | Details |
| A10868 | 31149745 | Aliment Pharmacol Ther | Review article: emerging role of the gut microbiome in the progression of nonalcoholic fatty liver disease and potential therapeutic implications. | 2019 | Details |