Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A10869 | 31149341 | Pharmacol Res Perspect | A structured literature review of interventions used in the management of nonalcoholic steatohepatitis (NASH). | 2019 | Details |
| A10871 | 31147590 | Sci Rep | Effects of açai on oxidative stress, ER stress, and inflammation-related parameters in mice with high fat diet-fed induced NAFLD. | 2019 | Details |
| A10877 | 31144415 | Hepatol Res | Autotaxin is a valuable biomarker for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A10886 | 31140156 | Hormones (Athens) | Non-alcoholic fatty liver infiltration in children: an underdiagnosed evolving disease. | 2019 | Details |
| A10891 | 31137547 | Medicina (Kaunas) | Dietary and Pharmacological Treatment of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10897 | 31135513 | Eur J Gastroenterol Hepatol | Fibroscan and low-density lipoprotein as determinants of severe liver fibrosis in diabetic patients with nonalcoholic fatty liver disease. | 2019 | Details |
| A10905 | 31131845 | Clin Infect Dis | Natural Course of Nonalcoholic Fatty Liver Disease and Type 2 Diabetes in Patients With Human Immunodeficiency Virus With and Without Combination Antiretroviral Therapy-associated Lipodystrophy: A 16-Year Follow-up Study. | 2020 | Details |
| A10907 | 31131153 | Am J Cardiovasc Dis | Ramipril significantly attenuates the development of non-alcoholic steatohepatitis in hyperlipidaemic rabbits. | 2019 | Details |
| A10910 | 31130411 | Ultrasound Med Biol | Considerations of Ultrasound Scanning Approaches in Non-alcoholic Fatty Liver Disease Assessment through Acoustic Structure Quantification. | 2019 | Details |
| A10911 | 31129048 | Biochem Pharmacol | A dual farnesoid X receptor/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice. | 2019 | Details |
| A10912 | 31128886 | J Pediatr | The Role of Genetic Predisposition, Programing During Fetal Life, Family Conditions, and Post-natal Diet in the Development of Pediatric Fatty Liver Disease. | 2019 | Details |
| A10919 | 31124558 | Am J Clin Nutr | Gut microbiome-targeted therapies in nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression. | 2019 | Details |
| A10921 | 31123622 | Liver Res | Autophagy in non-alcoholic fatty liver disease and alcoholic liver disease. | 2018 | Details |
| A10924 | 31120974 | PLoS One | Evaluation of rat liver with ARFI elastography: In vivo and ex vivo study. | 2019 | Details |
| A10929 | 31116779 | PLoS One | A study on hepatopathic, dyslipidemic and immunogenic properties of fructosylated-HSA-AGE and binding of autoantibodies in sera of obese and overweight patients with fructosylated-HSA-AGE. | 2019 | Details |
| A10932 | 31115065 | J Gastroenterol Hepatol | Type 2 diabetes mellitus: A risk factor for progression of liver fibrosis in middle-aged patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A10933 | 31114643 | World J Hepatol | Nonalcoholic fatty liver disease prevalence in an Italian cohort of patients with hidradenitis suppurativa: A multi-center retrospective analysis. | 2019 | Details |
| A10935 | 31114278 | Diabetes Metab Syndr Obes | Progressive reduction in skeletal muscle mass to visceral fat area ratio is associated with a worsening of the hepatic conditions of non-alcoholic fatty liver disease. | 2019 | Details |
| A10938 | 31113816 | J Lipid Res | Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis. | 2019 | Details |
| A10939 | 31113613 | Ann Hepatol | Lysosomal Acid Lipase: Can it be a New Non-Invasive Serum Biomarker of Cryptogenic Liver Fibrosis and Cirrhosis? | 2020 | Details |
| A10941 | 31113010 | Br J Pharmacol | Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity. | 2019 | Details |
| A10949 | 31107849 | Surg Laparosc Endosc Percutan Tech | The Effect of Laparoscopic Sleeve Gastrectomy on Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10953 | 31105018 | Ann Hepatol | "Hepatic toxicity by methotrexate with weekly single doses associated with folic acid in rheumatoid and psoriatic arthritis. What is its real frequency?" | 2019 | Details |
| A10956 | 31104523 | Expert Rev Gastroenterol Hepatol | A critical appraisal of the use of ultrasound in hepatic steatosis. | 2019 | Details |
| A10959 | 31102719 | J Hepatol | New sequential combinations of non-invasive fibrosis tests provide an accurate diagnosis of advanced fibrosis in NAFLD. | 2019 | Details |
| A10961 | 31101782 | Georgian Med News | COMPARATIVE ANALYSIS OF EFFICIENCY OF URSODEOXYCHOLIC ACID AND COMBINATION OF VITAMIN E AND VITAMIN C IN TREATMENT OF NON-DIABETIC NONALCOHOLIC STEATOHEPATITIS. | 2019 | Details |
| A10966 | 31100460 | Clin Gastroenterol Hepatol | Liver Stiffness Severity is Associated With Increased Cardiovascular Risk in Patients With Type 2 Diabetes. | 2019 | Details |
| A10967 | 31099410 | Aliment Pharmacol Ther | Non-alcoholic steatohepatitis, but not simple steatosis, disturbs the functional homogeneity of the liver - a human galactose positron emission tomography study. | 2019 | Details |
| A10979 | 31094171 | Ter Arkh | Comparative analysis of bile acid spectrum in non-alcoholic fatty liver disease and cholelithiasis. | 2019 | Details |
| A10981 | 31094016 | Aliment Pharmacol Ther | Moderate to severe hepatic steatosis leads to overestimation of liver stiffness measurement in chronic hepatitis B patients without significant fibrosis. | 2019 | Details |
| A10997 | 31086120 | Int J Mol Sci | Hepatoprotective Effect of Kombucha Tea in Rodent Model of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis. | 2019 | Details |
| A10998 | 31085647 | Proc Natl Acad Sci U S A | sGC stimulator praliciguat suppresses stellate cell fibrotic transformation and inhibits fibrosis and inflammation in models of NASH. | 2019 | Details |
| A10999 | 31085617 | Postgrad Med J | Diagnosis and management of non-alcoholic fatty liver disease. | 2019 | Details |
| A11001 | 31085337 | Clin Gastroenterol Hepatol | Alcoholic and Nonalcoholic Fatty Liver Disease and Incident Hospitalization for Liver and Cardiovascular Diseases. | 2019 | Details |
| A11010 | 31082799 | J Endocrinol | Impact of exenatide on mitochondrial lipid metabolism in mice with nonalcoholic steatohepatitis. | 2019 | Details |
| A11017 | 31081165 | Hepatology | Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice. | 2019 | Details |
| A11018 | 31080822 | Biomed Res Int | Diabetes Mellitus and Risk of Hepatic Fibrosis/Cirrhosis. | 2019 | Details |
| A11024 | 31078624 | Gastroenterology | Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis. | 2019 | Details |
| A11025 | 31078545 | Life Sci | Histological evaluation of nintedanib in non-alcoholic steatohepatitis mice. | 2019 | Details |
| A11027 | 31077838 | Clin Gastroenterol Hepatol | Daily Aspirin Use Associated With Reduced Risk For Fibrosis Progression In Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11030 | 31077025 | Obes Surg | Measurement of Liver Stiffness with 2D-Shear Wave Elastography (2D-SWE) in Bariatric Surgery Candidates Reveals Acceptable Diagnostic Yield Compared to Liver Biopsy. | 2019 | Details |
| A11033 | 31076231 | Ultrasound Med Biol | Characterizing Fatty Liver in vivo in Rabbits, Using Quantitative Ultrasound. | 2019 | Details |
| A11049 | 31068503 | Endocr J | High sex hormone-binding globulin concentration is a risk factor for high fibrosis-4 index in middle-aged Japanese men. | 2019 | Details |
| A11051 | 31067493 | Diabetes Metab | Association between non-alcoholic fatty liver disease and decreased lung function in adults: A systematic review and meta-analysis. | 2019 | Details |
| A11052 | 31065991 | Adv Ther | A Structured Literature Review of the Epidemiology and Disease Burden of Non-Alcoholic Steatohepatitis (NASH). | 2019 | Details |
| A11055 | 31064105 | J Clin Med | Cardiovascular Health Metrics in the Development and Regression of Nonalcoholic Fatty Liver Disease: A Cohort Study. | 2019 | Details |
| A11057 | 31064058 | Int J Mol Sci | Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A11059 | 31063640 | Hepatology | Pharmacologic Inhibition of Epidermal Growth Factor Receptor Suppresses Nonalcoholic Fatty Liver Disease in a Murine Fast-Food Diet Model. | 2019 | Details |
| A11062 | 31061949 | Hepatol Commun | Looking Into the Crystal Ball: Predicting the Future Challenges of Fibrotic NASH Treatment. | 2019 | Details |
| A11064 | 31061886 | JGH Open | Association between non-alcoholic fatty liver disease evaluated by transient elastography with extracranial carotid atherosclerosis in a multiethnic Asian community. | 2018 | Details |
| A11071 | 31058888 | J Vis Exp | Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution. | 2019 | Details |
| A11074 | 31057294 | World J Gastroenterol | Repurposing drugs to target nonalcoholic steatohepatitis. | 2019 | Details |
| A11079 | 31054980 | Ann Hepatol | Validation of PNPLA3 polymorphisms as risk factor for NAFLD and liver fibrosis in an admixed population. | 2019 | Details |
| A11084 | 31051106 | Cell | Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. | 2019 | Details |
| A11086 | 31049168 | Middle East J Dig Dis | Role of MicroRNAs in Pathophysiology of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis. | 2018 | Details |
| A11089 | 31046975 | Gastroenterol Clin North Am | Liver Fibrosis Determination. | 2019 | Details |
| A11090 | 31046673 | Mol Med | Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. | 2019 | Details |
| A11094 | 31045630 | Eur J Gastroenterol Hepatol | Comparison of anthropometric measurements for prediction of the atherosclerosis and liver histology in young adults with nonalcoholic fatty liver disease. | 2019 | Details |
| A11107 | 31039348 | Exp Cell Res | Epoxyeicosatrienoic intervention improves NAFLD in leptin receptor deficient mice by an increase in PGC1α-HO-1-PGC1α-mitochondrial signaling. | 2019 | Details |
| A11109 | 31038030 | Int J Vitam Nutr Res | Tissue Changes in the Development of Fatty Liver by Chronic Ingestion of Sucrose Associated with Obesity and Dyslipidemia in Rats. | 2019 | Details |
| A11111 | 31036530 | EBioMedicine | A PDGFRβ-based score predicts significant liver fibrosis in patients with chronic alcohol abuse, NAFLD and viral liver disease. | 2019 | Details |
| A11114 | 31035991 | BMC Complement Altern Med | The Alisma and Rhizoma decoction abates nonalcoholic steatohepatitis-associated liver injuries in mice by modulating oxidative stress and autophagy. | 2019 | Details |
| A11118 | 31034092 | Hepatology | Defining Improvement in Nonalcoholic Steatohepatitis for Treatment Trial Endpoints: Recommendations From the Liver Forum. | 2019 | Details |
| A11128 | 31031166 | Ann Hepatol | Transient hepatic elastography has the best performance to evaluate liver fibrosis in non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A11131 | 31029645 | Clin Res Hepatol Gastroenterol | Noninvasive diagnosis of liver fibrosis in NAFLD: Tips tricks. | 2019 | Details |
| A11135 | 31027093 | Medicine (Baltimore) | Glycogenic hepatopathy as an unusual etiology of deranged liver function in a patient with type 1 diabetes: A case report. | 2019 | Details |
| A11138 | 31026041 | Swiss Med Wkly | Controlled attenuation parameter for the assessment of liver steatosis in comparison with liver histology: a single-centre real life experience. | 2019 | Details |
| A11139 | 31025557 | Adv Clin Exp Med | Clinical outcomes of non-alcoholic fatty liver disease: Polish-case control study. | 2019 | Details |
| A11142 | 31024203 | J Clin Exp Hepatol | Therapy with Oral Directly Acting Agents in Hepatitis C Infection Is Associated with Reduction in Fibrosis and Increase in Hepatic Steatosis on Transient Elastography. | 2018 | Details |
| A11145 | 31024199 | J Clin Exp Hepatol | Clinical, anthropometric, biochemical and histological character of nonalcoholic fatty liver disease without Insulin Resistance. | 2018 | Details |
| A11148 | 31023717 | Biol Open | Longitudinal characterization of diet-induced genetic murine models of non-alcoholic steatohepatitis with metabolic, histological, and transcriptomic hallmarks of human patients. | 2019 | Details |
| A11149 | 31022865 | Nutrients | Dietary Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) Operate by Different Mechanisms to Modulate Hepatic Steatosis and Hyperinsulemia in fa/fa Zucker Rats. | 2019 | Details |
| A11156 | 31019294 | Lab Invest | Pirfenidone prevents and reverses hepatic insulin resistance and steatohepatitis by polarizing M2 macrophages. | 2019 | Details |
| A11158 | 31018673 | Angiology | The Nonalcoholic Fatty Liver Disease Fibrosis Score Is Related to Epicardial Fat Thickness and Complexity of Coronary Artery Disease. | 2019 | Details |
| A11163 | 31014948 | Surg Obes Relat Dis | Risk factors and prevalence of liver disease in review of 2557 routine liver biopsies performed during bariatric surgery. | 2019 | Details |
| A11171 | 31011515 | Anal Cell Pathol (Amst) | Can Nonfibrotic Nonalcoholic Steatohepatitis Be Effectively Identified by Supersonic Shear Imaging? | 2019 | Details |
| A11172 | 31011312 | Case Rep Gastroenterol | Gut Microbiota Profiles in Nonalcoholic Fatty Liver Disease and Its Possible Impact on Disease Progression Evaluated with Transient Elastography: Lesson Learnt from 60 Cases. | 2019 | Details |
| A11173 | 31011302 | Gastroenterol Hepatol (N Y) | Diagnostic and Treatment Implications of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2019 | Details |
| A11175 | 31010457 | Gene Expr | Nonalcoholic Fatty Liver Disease: An Update on the Diagnosis. | 2019 | Details |
| A11180 | 31009403 | Clin Transl Gastroenterol | Liver Stiffness Measurement With FibroScan: Use the Right Probe in the Right Conditions! | 2019 | Details |
| A11181 | 31009401 | Eur J Gastroenterol Hepatol | The promising role of probiotic and synbiotic therapy in aminotransferase levels and inflammatory markers in patients with nonalcoholic fatty liver disease - a systematic review and meta-analysis. | 2019 | Details |
| A11182 | 31009107 | J Cell Biochem | Hypoxia inducible factor-1 promotes liver fibrosis in nonalcoholic fatty liver disease by activating PTEN/p65 signaling pathway. | 2019 | Details |
| A11196 | 31004178 | Arch Toxicol | A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice. | 2019 | Details |
| A11206 | 30999770 | Scand J Gastroenterol | Characteristics and risk factors for recurrence of nonalcoholic steatohepatitis following liver transplantation. | 2019 | Details |
| A11213 | 30993748 | Hepatology | The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials. | 2019 | Details |
| A11214 | 30993598 | Hepatol Int | Bi-lobar liver biopsy via EUS enhances the assessment of disease severity in patients with non-alcoholic steatohepatitis. | 2019 | Details |
| A11226 | 30986904 | Int J Mol Sci | Human Multilineage 3D Spheroids as a Model of Liver Steatosis and Fibrosis. | 2019 | Details |
| A11228 | 30984539 | FEBS Open Bio | Inhibition of sodium glucose cotransporter 2 (SGLT2) delays liver fibrosis in a medaka model of nonalcoholic steatohepatitis (NASH). | 2019 | Details |
| A11229 | 30983887 | J Inflamm (Lond) | Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease. | 2019 | Details |
| A11233 | 30982168 | Obes Surg | Vertical Sleeve Gastrectomy Attenuates the Progression of Non-Alcoholic Steatohepatitis in Mice on a High-Fat High-Cholesterol Diet. | 2019 | Details |
| A11235 | 30981560 | J Formos Med Assoc | A community-based study on the application of fatty liver index in screening subjects with nonalcoholic fatty liver disease. | 2019 | Details |
| A11239 | 30978348 | Life Sci | Periostin in chronic liver diseases: Current research and future perspectives. | 2019 | Details |
| A11245 | 30975991 | Nat Commun | Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα. | 2019 | Details |
| A11249 | 30974498 | Hepatol Res | Assessment of 10-year changes in liver stiffness using vibration-controlled transient elastography in non-alcoholic fatty liver disease. | 2019 | Details |
| A11250 | 30973968 | Br J Clin Pharmacol | Hepatic exposure of metformin in patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A11257 | 30972062 | Front Immunol | Targeting Myeloid-Derived Cells: New Frontiers in the Treatment of Non-alcoholic and Alcoholic Liver Disease. | 2019 | Details |
| A11260 | 30970564 | Int J Mol Sci | Recent Insight into the Role of Fibrosis in Nonalcoholic Steatohepatitis-Related Hepatocellular Carcinoma. | 2019 | Details |
| A11261 | 30970434 | Gut Liver | Noninvasive Serum Fibrosis Markers are Associated with Coronary Artery Calcification in Patients with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11267 | 30968536 | Liver Int | Prescription of statins in suspected non-alcoholic fatty liver disease and high cardiovascular risk, a population-based study. | 2019 | Details |
| A11269 | 30965381 | Z Gastroenterol | Nonalcoholic steatohepatitis (NASH) - current treatment recommendations and future developments. | 2019 | Details |