Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19001 | 26825546 | Eur J Pharmacol | Effects of combined PPAR-γ and PPAR-α agonist therapy on fructose induced NASH in rats: Modulation of gene expression. | 2016 | Details |
| A19006 | 26823198 | Metabolism | The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A19012 | 26819531 | World J Gastroenterol | Mechanisms of intrahepatic triglyceride accumulation. | 2016 | Details |
| A19013 | 26819197 | Sci Transl Med | The intersection of nonalcoholic fatty liver disease and obesity. | 2016 | Details |
| A19019 | 26817127 | Eksp Klin Gastroenterol | [NONALCOHOLIC FATTY LIVER DISEASE: DIAGNOSTIC, SYMPTOMS, TREATMENT. GUIDELINES WERE APPROVED BY THE XV GASTROENTEROLOGICAL SCIENTIFIC SOCIETY OF RUSSIA IN 2015]. | 2015 | Details |
| A19024 | 26814015 | Am J Physiol Endocrinol Metab | Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity. | 2016 | Details |
| A19025 | 26813367 | Zhonghua Yi Xue Za Zhi | [Clinical features of non-alcoholic fatty liver disease and its relationship with serum C-peptide levels in patients with latent autoimmune diabetes in adults]. | 2015 | Details |
| A19032 | 26811103 | Exp Biol Med (Maywood) | Women may respond different from men to vitamin D supplementation regarding cardiometabolic biomarkers. | 2016 | Details |
| A19044 | 26806650 | Hepatology | Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice. | 2016 | Details |
| A19047 | 26805014 | Metabolism | Exercise and diet in the management of nonalcoholic fatty liver disease. | 2015 | Details |
| A19048 | 26803754 | Obes Surg | The Correlation Between Obesity-Related Diseases and Non-alcoholic Fatty Liver Disease in Women in the Pre-operative Evaluation for Bariatric Surgery Assessed by Transient Hepatic Elastography. | 2016 | Details |
| A19051 | 26800495 | J Diabetes | Age at menarche is associated with the prevalence of non-alcoholic fatty liver disease later in life. | 2016 | Details |
| A19055 | 26797396 | Am J Physiol Gastrointest Liver Physiol | Pioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine N-methyltransferase-deficient mice. | 2016 | Details |
| A19058 | 26794005 | J Gastroenterol | Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice. | 2016 | Details |
| A19061 | 26791191 | Am J Clin Nutr | Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level. | 2016 | Details |
| A19063 | 26788524 | J Diabetes Res | A Novel Wistar Rat Model of Obesity-Related Nonalcoholic Fatty Liver Disease Induced by Sucrose-Rich Diet. | 2015 | Details |
| A19066 | 26786607 | Sao Paulo Med J | Influence of type 2 diabetes mellitus on liver histology among morbidly obese individuals. A cross-sectional study. | 2016 | Details |
| A19067 | 26786351 | Int J Obes (Lond) | Strong and persistent effect on liver fat with a Paleolithic diet during a two-year intervention. | 2016 | Details |
| A19068 | 26785389 | Hepatol Res | The independent predictors of non-alcoholic steatohepatitis and its individual histological features.: Insulin resistance, serum uric acid, metabolic syndrome, alanine aminotransferase and serum total cholesterol are a clue to pathogenesis and candidate targets for treatment. | 2016 | Details |
| A19075 | 26780287 | J Hepatol | Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A19082 | 26775559 | Metabolism | Histopathology of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2015 | Details |
| A19083 | 26775542 | Biosci Biotechnol Biochem | Long-term fatty liver-induced insulin resistance in orotic acid-induced nonalcoholic fatty liver rats. | 2016 | Details |
| A19084 | 26774456 | Biochem Pharmacol | Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer. | 2016 | Details |
| A19091 | 26770987 | J Diabetes Res | Nutrition and Physical Activity in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19095 | 26770473 | Int J Clin Exp Med | Absence of non-alcoholic fatty liver disease in the presence of insulin resistance is a strong predictor for colorectal carcinoma. | 2015 | Details |
| A19107 | 26761949 | J Clin Res Pediatr Endocrinol | Sex Hormone-Binding Globulin in Children and Adolescents. | 2015 | Details |
| A19109 | 26758497 | J Clin Res Pediatr Endocrinol | Relationship between Neck Circumference and Non-Alcoholic Fatty Liver Disease in Childhood Obesity. | 2015 | Details |
| A19112 | 26756202 | Diabet Med | Familial partial lipodystrophy linked to a novel peroxisome proliferator activator receptor -γ (PPARG) mutation, H449L: a comparison of people with this mutation and those with classic codon 482 Lamin A/C (LMNA) mutations. | 2016 | Details |
| A19113 | 26755885 | World J Gastroenterol | Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents. | 2016 | Details |
| A19114 | 26755867 | World J Gastroenterol | Association between hepatitis B and metabolic syndrome: Current state of the art. | 2016 | Details |
| A19115 | 26755815 | J Investig Med | Plasma thyroid hormone concentration is associated with hepatic triglyceride content in patients with type 2 diabetes. | 2015 | Details |
| A19117 | 26753695 | Naunyn Schmiedebergs Arch Pharmacol | Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis. | 2016 | Details |
| A19136 | 26733747 | Clujul Med | Non-alcoholic fatty liver disease severity, central fat mass and adinopectin: a close relationship. | 2015 | Details |
| A19139 | 26732252 | Sci Rep | Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. | 2016 | Details |
| A19142 | 26731267 | PLoS One | The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice. | 2016 | Details |
| A19144 | 26728862 | Turk J Gastroenterol | Ovaries are more vulnerable than hepatocytes for insulin resistance and hyperinsulinemia. | 2016 | Details |
| A19146 | 26728273 | BMB Rep | The role of lipids in the pathogenesis and treatment of type 2 diabetes and associated co-morbidities. | 2016 | Details |
| A19160 | 26720346 | Cell Death Dis | Obesity and cancer, a case for insulin signaling. | 2015 | Details |
| A19162 | 26718936 | J Diabetes Complications | Optimal cutoff points for HOMA-IR and QUICKI in the diagnosis of metabolic syndrome and non-alcoholic fatty liver disease: A population based study. | 2015 | Details |
| A19178 | 29889391 | Eksp Klin Gastroenterol | NON-ALCOHOLIC FATTY LIVER DISEASE IN ELDERLY. | 2018 | Details |
| A19182 | 29201718 | Euroasian J Hepatogastroenterol | Reduced Glutathione suppresses Oxidative Stress in Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A19186 | 28670148 | Clin Med Insights Ther | Nonalcoholic Fatty Liver Disease: Epidemiology, Pathogenesis, Natural History, Diagnosis, and Current Treatment Options. | 2016 | Details |
| A19188 | 28614648 | Eksp Klin Gastroenterol | [[The Modern View on Pathogenesis and Treatment of Nonalcoholic Fatty Liver Disease].] | 2016 | Details |
| A19190 | 28332698 | Mol Med | Induction of steatohepatitis (NASH) with insulin resistance in wildtype B6 mice by a western-type diet containing soybean oil and cholesterol. | 2017 | Details |
| A19196 | 26713058 | J Korean Med Sci | Vitamin D Status and Bone Mineral Density in Obese Children with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19211 | 26699443 | J Gastroenterol Hepatol | Red pitaya betacyanins protects from diet-induced obesity, liver steatosis and insulin resistance in association with modulation of gut microbiota in mice. | 2016 | Details |
| A19220 | 26697286 | Springerplus | Global publication trends and research hotspots of nonalcoholic fatty liver disease: a bibliometric analysis and systematic review. | 2015 | Details |
| A19222 | 26695389 | Can J Physiol Pharmacol | Irisin levels in relation to metabolic and liver functions in Egyptian patients with metabolic syndrome. | 2015 | Details |
| A19226 | 26690419 | Int J Mol Sci | Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. | 2015 | Details |
| A19239 | 26678309 | BMC Gastroenterol | Deficiency of eNOS exacerbates early-stage NAFLD pathogenesis by changing the fat distribution. | 2015 | Details |
| A19240 | 26678239 | J Gastroenterol Hepatol | Follicle-stimulating hormone is associated with non-alcoholic fatty liver disease in Chinese women over 55 years old. | 2016 | Details |
| A19242 | 26676813 | Semin Liver Dis | Insights from Genome-Wide Association Analyses of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19244 | 26675585 | BBA Clin | Clinical spectrum of non-alcoholic fatty liver disease in diabetic and non-diabetic patients. | 2014 | Details |
| A19249 | 26674248 | BBA Clin | Mechanism of the development of nonalcoholic steatohepatitis after pancreaticoduodenectomy. | 2015 | Details |
| A19253 | 26672634 | J Clin Endocrinol Metab | Hepatic Steatosis and Insulin Resistance, But Not Steatohepatitis, Promote Atherogenic Dyslipidemia in NAFLD. | 2015 | Details |
| A19256 | 26670487 | Am J Physiol Endocrinol Metab | Metabolic phenotype and adipose and liver features in a high-fat Western diet-induced mouse model of obesity-linked NAFLD. | 2015 | Details |
| A19259 | 26668692 | World J Hepatol | Bile acid receptors and nonalcoholic fatty liver disease. | 2015 | Details |
| A19268 | 26666594 | Intern Med | The Symptoms of Gastroesophageal Reflux Disease Correlate with High Body Mass Index, the Aspartate Aminotransferase/Alanine Aminotransferase Ratio and Insulin Resistance in Japanese Patients with Non-alcoholic Fatty Liver Disease. | 2015 | Details |
| A19272 | 26663034 | Acta Physiol (Oxf) | Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress. | 2015 | Details |
| A19277 | 26660688 | Obes Surg | Combined Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Sleeve Gastrectomy or Gastric Bypass?-a Controlled Matched Pair Study of 34 Patients. | 2016 | Details |
| A19287 | 26650570 | Endocrinology | Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice. | 2015 | Details |
| A19289 | 26648069 | Curr Drug Targets | Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib. | 2016 | Details |
| A19290 | 26646939 | Sci Data | Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes. | 2015 | Details |
| A19292 | 26645107 | J Cell Mol Med | Role of stem cells during diabetic liver injury. | 2015 | Details |
| A19295 | 26642701 | Clin Lab | Therapeutic Effect of Metformin on Chemerin in Non-Obese Patients with Non-Alcoholic Fatty Liver Disease (NAFLD). | 2015 | Details |
| A19296 | 26641143 | Expert Rev Gastroenterol Hepatol | The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development--a potential therapeutic target? | 2015 | Details |
| A19299 | 26639394 | J Hepatol | Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism. | 2015 | Details |
| A19304 | 26638128 | Hepatology | Sarcopenia is associated with significant liver fibrosis independently of obesity and insulin resistance in nonalcoholic fatty liver disease: Nationwide surveys (KNHANES 2008-2011). | 2016 | Details |
| A19306 | 26636520 | Eur Rev Med Pharmacol Sci | Is it possible a new definition of metabolic syndrome in childhood? | 2015 | Details |
| A19309 | 26636404 | Eur J Gastroenterol Hepatol | Association of nonalcoholic fatty liver disease with bone mineral density and serum osteocalcin levels in Korean men. | 2016 | Details |
| A19319 | 26631018 | Lipids Health Dis | Research advances in the relationship between nonalcoholic fatty liver disease and atherosclerosis. | 2015 | Details |
| A19323 | 26629547 | EBioMedicine | Circulating Unsaturated Fatty Acids Delineate the Metabolic Status of Obese Individuals. | 2015 | Details |
| A19328 | 26628836 | J Clin Exp Hepatol | Remogliflozin Etabonate Improves Fatty Liver Disease in Diet-Induced Obese Male Mice. | 2015 | Details |
| A19343 | 26619823 | Sci Rep | Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model. | 2015 | Details |
| A19345 | 26618774 | PLoS One | A Prospective Study of Fatty Liver Index and Incident Hypertension: The KoGES-ARIRANG Study. | 2015 | Details |
| A19351 | 26613006 | Diabetol Metab Syndr | The association of circulating levels of complement-C1q TNF-related protein 5 (CTRP5) with nonalcoholic fatty liver disease and type 2 diabetes: a case-control study. | 2015 | Details |
| A19360 | 26608256 | Lancet | Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study. | 2015 | Details |
| A19363 | 26603489 | Sci Rep | Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. | 2015 | Details |
| A19377 | 26599819 | PLoS One | Lipoprotein Profiles in Class III Obese Caucasian and African American Women with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19379 | 26599361 | PLoS One | Phenotype, Body Composition, and Prediction Equations (Indian Fatty Liver Index) for Non-Alcoholic Fatty Liver Disease in Non-Diabetic Asian Indians: A Case-Control Study. | 2015 | Details |
| A19384 | 26597657 | Obes Rev | Association of recently described adipokines with liver histology in biopsy-proven non-alcoholic fatty liver disease: a systematic review. | 2015 | Details |
| A19385 | 26597602 | J Diabetes Complications | Chronic fructose intake accelerates non-alcoholic fatty liver disease in the presence of essential hypertension. | 2015 | Details |
| A19388 | 26594248 | Diabetol Metab Syndr | Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus. | 2015 | Details |
| A19389 | 26594198 | Front Endocrinol (Lausanne) | Sexual Dimorphism of Adipose and Hepatic Aquaglyceroporins in Health and Metabolic Disorders. | 2015 | Details |
| A19390 | 26593707 | Eur J Pharmacol | Betaine prevented fructose-induced NAFLD by regulating LXRα/PPARα pathway and alleviating ER stress in rats. | 2015 | Details |
| A19398 | 26592314 | Proc Nutr Soc | Polyphenols and non-alcoholic fatty liver disease: impact and mechanisms. | 2015 | Details |
| A19402 | 26589977 | J Gastroenterol Hepatol | Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boys. | 2016 | Details |
| A19405 | 26587039 | Hepat Mon | Effect of Aerobic and Resistance Exercise Training on Liver Enzymes and Hepatic Fat in Iranian Men With Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19417 | 26580662 | J Clin Med | MicroRNA Expression Relating to Dietary-Induced Liver Steatosis and NASH. | 2015 | Details |
| A19418 | 26580649 | Nutrients | The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis. | 2015 | Details |
| A19424 | 26576055 | PLoS One | Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls. | 2015 | Details |
| A19426 | 26573193 | Zhonghua Gan Zang Bing Za Zhi | [Relationship of socioeconomic status and non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus]. | 2015 | Details |
| A19431 | 26571396 | J Clin Invest | Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. | 2015 | Details |
| A19436 | 26569494 | PLoS One | Gender Specific Association of Serum Leptin and Insulinemic Indices with Nonalcoholic Fatty Liver Disease in Prediabetic Subjects. | 2015 | Details |
| A19446 | 26566287 | PLoS One | Non-Alcoholic Fatty Liver Disease Is a Risk Factor for the Development of Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus. | 2015 | Details |
| A19459 | 26557952 | World J Hepatol | Dietary supplements and pediatric non-alcoholic fatty liver disease: Present and the future. | 2015 | Details |
| A19462 | 26556368 | Nutrients | Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance. | 2015 | Details |
| A19469 | 26547273 | Med Hypotheses | Involvement of steatosis-induced glucagon resistance in hyperglucagonaemia. | 2015 | Details |
| A19472 | 26540639 | Ren Fail | Increased microalbuminuria prevalence among patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A19485 | 26528424 | J Lifestyle Med | Comorbidities and Metabolic Derangement of NAFLD. | 2015 | Details |