Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A25048 | 22215535 | IUBMB Life | Association of nonalcoholic fatty liver disease with a single nucleotide polymorphism on the gene encoding leptin receptor. | 2012 | Details |
| A25054 | 22209939 | Biochim Biophys Acta | Apolipoprotein A-V dependent modulation of plasma triacylglycerol: a puzzlement. | 2011 | Details |
| A25056 | 33907358 | J Proteomics Bioinform | High Fat Diet-Induced Changes in Hepatic Protein Abundance in Mice. | 2012 | Details |
| A25066 | 23750438 | Przegl Lek | [Nonalcoholic fatty liver disease as a risk factor of macroangiopahty in patients with type 2 diabetes]. | 2012 | Details |
| A25083 | 22183915 | Hepatology | Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease. | 2012 | Details |
| A25084 | 22183894 | Mol Med | Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis. | 2012 | Details |
| A25094 | 22176347 | Hepatol Res | High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism. | 2011 | Details |
| A25098 | 22173168 | J Hepatol | The interaction of hepatic lipid and glucose metabolism in liver diseases. | 2011 | Details |
| A25101 | 22170794 | Eur J Endocrinol | Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies. | 2011 | Details |
| A25113 | 22160635 | Dig Dis Sci | Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD. | 2011 | Details |
| A25119 | 22155365 | Gastroenterology | Autophagy protects cells from HCV-induced defects in lipid metabolism. | 2011 | Details |
| A25121 | 22154950 | Dig Liver Dis | Inverse correlation between plasma oxysterol and LDL-cholesterol levels in hepatitis C virus-infected patients. | 2011 | Details |
| A25126 | 22152380 | Zhonghua Gan Zang Bing Za Zhi | [SREBP-1c knockdown attenuated fatty degeneration in hepatic L02 cells and inhibited CCL2 and FGF21 protein expression]. | 2011 | Details |
| A25127 | 22152379 | Zhonghua Gan Zang Bing Za Zhi | [Establishment and identification of non-alcoholic fatty liver disease in chronic hepatitis B virus infected mice]. | 2011 | Details |
| A25140 | 22147010 | Endocrinology | Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance. | 2011 | Details |
| A25160 | 22124850 | Curr Gastroenterol Rep | Iron metabolism in Nonalcoholic Fatty Liver Disease. | 2012 | Details |
| A25164 | 22120683 | J Ethnopharmacol | Lipid regulation effects of Polygoni Multiflori Radix, its processed products and its major substances on steatosis human liver cell line L02. | 2011 | Details |
| A25191 | 22103753 | Pharm Biol | Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: impact of nonalcoholic fatty liver disease. | 2011 | Details |
| A25220 | 22083307 | Mol Cells | Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease. | 2011 | Details |
| A25222 | 22082335 | Chem Res Toxicol | Glutathione-deficient mice are susceptible to TCDD-Induced hepatocellular toxicity but resistant to steatosis. | 2011 | Details |
| A25228 | 22076166 | Int J Clin Exp Pathol | Increased expression of zinc finger protein 267 in non-alcoholic fatty liver disease. | 2011 | Details |
| A25237 | 22064320 | Lab Invest | A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein. | 2011 | Details |
| A25243 | 22053378 | Zhonghua Gan Zang Bing Za Zhi | [The effects of curcumin derivative on experimental steatohepatitis]. | 2011 | Details |
| A25270 | 22023985 | J Hepatol | Omega-3 supplementation and non-alcoholic fatty liver disease: a systematic review and meta-analysis. | 2011 | Details |
| A25292 | 21989716 | Mol Cell Biochem | Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a high fat thermolyzed diet. | 2011 | Details |
| A25294 | 21987620 | World J Gastroenterol | JNKs, insulin resistance and inflammation: A possible link between NAFLD and coronary artery disease. | 2011 | Details |
| A25298 | 21986673 | Eur J Nutr | Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFα. | 2011 | Details |
| A25316 | 21963507 | Biol Pharm Bull | meso-Dihydroguaiaretic acid inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells. | 2011 | Details |
| A25319 | 21958877 | Eur J Pharmacol | Metformin regulates hepatic lipid metabolism through activating AMP-activated protein kinase and inducing ATGL in laying hens. | 2011 | Details |
| A25336 | 21949781 | PLoS One | Circulating fibroblast growth factor 21 levels are closely associated with hepatic fat content: a cross-sectional study. | 2011 | Details |
| A25341 | 21947639 | Nutr Clin Pract | Nonalcoholic fatty liver disease: a review of the spectrum of disease, diagnosis, and therapy. | 2011 | Details |
| A25355 | 21932408 | Hepatology | Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver. | 2011 | Details |
| A25360 | 21929649 | J Gastroenterol Hepatol | Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis. | 2012 | Details |
| A25365 | 21905818 | Int J Pediatr Obes | Fatty liver disease in obese children--relation to other metabolic risk factors. | 2011 | Details |
| A25376 | 21910083 | Adv Exp Med Biol | Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity. | 2011 | Details |
| A25380 | 21906580 | Am J Pathol | Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25386 | 21901160 | PLoS One | Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning. | 2011 | Details |
| A25391 | 21894552 | J Mol Med (Berl) | Genetic variants in candidate genes influencing NAFLD progression. | 2011 | Details |
| A25421 | 21875072 | J Agric Food Chem | Synthesis of carboxymethylated and quaternized chitosans and their therapeutic effect on nonalcoholic Fatty liver disease. | 2011 | Details |
| A25429 | 21857953 | PLoS One | Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine model. | 2011 | Details |
| A25432 | 21853118 | PLoS One | Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets. | 2011 | Details |
| A25444 | 21835806 | J Gerontol A Biol Sci Med Sci | Aging is associated with a shift of fatty metabolism toward lipogenesis. | 2011 | Details |
| A25448 | 21821952 | Biosci Biotechnol Biochem | Isolation and anti-fatty liver activity of a novel cerebroside from the sea cucumber Acaudina molpadioides. | 2011 | Details |
| A25453 | 21817060 | Am J Physiol Gastrointest Liver Physiol | Altered lipid metabolism in Hfe-knockout mice promotes severe NAFLD and early fibrosis. | 2011 | Details |
| A25488 | 21773586 | Food Funct | The impact of choline availability on muscle lipid metabolism. | 2010 | Details |
| A25500 | 21764575 | J Nutr Biochem | Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice. | 2011 | Details |
| A25542 | 21733354 | Chang Gung Med J | Disrupted hepatic adiponectin signaling impairs liver regeneration of steatotic rats. | 2011 | Details |
| A25543 | 21733326 | Br J Nutr | Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress. | 2011 | Details |
| A25551 | 21723839 | J Hepatol | Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review. | 2011 | Details |
| A25557 | 21713513 | Appl Microbiol Biotechnol | Large-scale expression, purification, and glucose uptake activity of recombinant human FGF21 in Escherichia coli. | 2011 | Details |
| A25563 | 21708823 | Gut | Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. | 2011 | Details |
| A25565 | 21707532 | Mini Rev Med Chem | Farnesoid X receptor agonist for the treatment of liver and metabolic disorders: focus on 6-ethyl-CDCA. | 2011 | Details |
| A25583 | 21689150 | J Pineal Res | Melatonin alleviates lipopolysaccharide-induced hepatic SREBP-1c activation and lipid accumulation in mice. | 2011 | Details |
| A25603 | 21663607 | Lipids Health Dis | Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans. | 2011 | Details |
| A25607 | 21655948 | Dig Dis Sci | Mechanisms linking nonalcoholic fatty liver disease with coronary artery disease. | 2011 | Details |
| A25609 | 21651352 | Expert Rev Gastroenterol Hepatol | Animal models in the study of hepatitis C virus-associated liver pathologies. | 2011 | Details |
| A25627 | 21629127 | J Pediatr Gastroenterol Nutr | Mechanisms of lipotoxicity in NAFLD and clinical implications. | 2011 | Details |
| A25628 | 21629037 | Am J Med Sci | Lipid targets during statin treatment in dyslipidemic patients affected by nonalcoholic fatty liver disease. | 2011 | Details |
| A25629 | 21626400 | J Physiol Biochem | Vitamin A and lipid metabolism: relationship between hepatic stellate cells (HSCs) and adipocytes. | 2011 | Details |
| A25630 | 21624329 | Zhonghua Yu Fang Yi Xue Za Zhi | [Effects of soybean isoflavone on liver lipid metabolism in nonalcoholic fatty liver rats]. | 2011 | Details |
| A25633 | 21621638 | Biochim Biophys Acta | Differential effects of short- and long-term high-fat diet feeding on hepatic fatty acid metabolism in rats. | 2011 | Details |
| A25639 | 21616061 | Biochem Biophys Res Commun | Soluble FGFR4 extracellular domain inhibits FGF19-induced activation of FGFR4 signaling and prevents nonalcoholic fatty liver disease. | 2011 | Details |
| A25647 | 21599535 | Crit Rev Biochem Mol Biol | Insulin signaling to hepatic lipid metabolism in health and disease. | 2011 | Details |
| A25650 | 21595271 | Nihon Rinsho | [Attenuation of fatty accumulation in hepatocyte by incretin--expectation of novel medicine for treatment of NASH]. | 2011 | Details |
| A25658 | 21570653 | Eur J Intern Med | Alterations in lipid, carbohydrate and iron metabolism in patients with non-alcoholic steatohepatitis (NASH) and metabolic syndrome. | 2011 | Details |
| A25682 | 21549692 | Eur J Pharmacol | Effects of bezafibrate in nonalcoholic steatohepatitis model mice with monosodium glutamate-induced metabolic syndrome. | 2011 | Details |
| A25699 | 21525818 | Med Sci Monit | SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease. | 2011 | Details |
| A25753 | 21479224 | PLoS One | Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation. | 2011 | Details |
| A25757 | 21476921 | Expert Rev Gastroenterol Hepatol | Organelle dysfunction in hepatitis C virus-associated steatosis: anything to learn from nonalcoholic steatohepatitis? | 2011 | Details |
| A25758 | 21476920 | Expert Rev Gastroenterol Hepatol | Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease. | 2011 | Details |
| A25759 | 21476919 | Expert Rev Gastroenterol Hepatol | Microsomal triglyceride transfer protein and nonalcoholic fatty liver disease. | 2011 | Details |
| A25760 | 21476918 | Expert Rev Gastroenterol Hepatol | Mitochondrial dysfunction in nonalcoholic steatohepatitis. | 2011 | Details |
| A25764 | 21476914 | Expert Rev Gastroenterol Hepatol | Inflammation in nonalcoholic steatohepatitis. | 2011 | Details |
| A25767 | 21476911 | Expert Rev Gastroenterol Hepatol | Autophagy in nonalcoholic steatohepatitis. | 2011 | Details |
| A25774 | 21474829 | Arterioscler Thromb Vasc Biol | Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice. | 2011 | Details |
| A25777 | 21470125 | Curr Pharm Biotechnol | Methodologies for investigating natural medicines for the treatment of nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
| A25801 | 21445622 | Eur J Nutr | Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats. | 2011 | Details |
| A25822 | 21426695 | Zhonghua Er Ke Za Zhi | [Metformin prevents non-alcoholic fatty liver disease in rats: role of phospholipase A2/lysophosphatidylcholine lipoapoptosis pathway in hepatocytes]. | 2011 | Details |
| A25837 | 21411114 | Metabolism | Treatment with insulin sensitizer metformin improves arterial properties, metabolic parameters, and liver function in patients with nonalcoholic fatty liver disease: a randomized, placebo-controlled trial. | 2011 | Details |
| A25845 | 21401612 | J Pharm Pharmacol | Hepatoprotective effects of geniposide in a rat model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25860 | 21382219 | Br J Nutr | Neonatal exposure to genistein ameliorates high-fat diet-induced non-alcoholic steatohepatitis in rats. | 2011 | Details |
| A25866 | 21378565 | Curr Opin Lipidol | Lipidomics is providing new insight into the metabolic syndrome and its sequelae. | 2011 | Details |
| A25880 | 21359922 | Chin J Integr Med | Effect of berberine on expressions of uncoupling protein-2 mRNA and protein in hepatic tissue of non-alcoholic fatty liver disease in rats. | 2011 | Details |
| A25905 | 21339203 | Gut | The role of apolipoprotein A5 in non-alcoholic fatty liver disease. | 2011 | Details |
| A25912 | 21333494 | Nutrition | Soy protein retards the progression of non-alcoholic steatohepatitis via improvement of insulin resistance and steatosis. | 2011 | Details |
| A25916 | 21331443 | Int J Mol Med | Association between lipid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes. | 2011 | Details |
| A25919 | 21327921 | Dig Dis Sci | Correlation analysis between gene expression profile of rat liver tissues and high-fat emulsion-induced nonalcoholic fatty liver. | 2011 | Details |
| A25922 | 21325336 | Acta Biochim Biophys Sin (Shanghai) | PGC-1 coactivators in the control of energy metabolism. | 2011 | Details |
| A25926 | 21319202 | Hepatology | Nuclear receptors in liver disease. | 2011 | Details |
| A25942 | 21286345 | Hepatol Int | Effects of nuclear receptor FXR on the regulation of liver lipid metabolism in patients with non-alcoholic fatty liver disease. | 2010 | Details |
| A25953 | 21274430 | Gastroenterol Res Pract | Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. | 2011 | Details |
| A25955 | 21269482 | Lipids Health Dis | Comparison of dietary control and atorvastatin on high fat diet induced hepatic steatosis and hyperlipidemia in rats. | 2011 | Details |
| A25961 | 21261727 | J Gastroenterol Hepatol | Reversal of hepatic steatosis by omega-3 fatty acids measured non-invasively by (1) H-magnetic resonance spectroscopy in a rat model. | 2011 | Details |
| A26000 | 21223809 | Zhonghua Yi Xue Za Zhi | [Relationship between liver fat content and liver enzymes in individuals with various statuses of glucose metabolism]. | 2010 | Details |
| A26016 | 21198182 | J Biomed Opt | Nonlinear microscopy of lipid storage and fibrosis in muscle and liver tissues of mice fed high-fat diets. | 2011 | Details |
| A26023 | 22580727 | Rev Diabet Stud | Hepatic steatosis in type 1 diabetes. | 2012 | Details |
| A26032 | 21184786 | J Hepatol | Deletion of steroid receptor coactivator-3 gene ameliorates hepatic steatosis. | 2010 | Details |
| A26033 | 21184785 | J Hepatol | Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis. | 2010 | Details |
| A26070 | 21145833 | J Hepatol | Direct effects of iodothyronines on excess fat storage in rat hepatocytes. | 2010 | Details |
| A26073 | 21145823 | J Hepatol | Galectin-3 ablation protects mice from diet-induced NASH: a major scavenging role for galectin-3 in liver. | 2010 | Details |