Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A21846 | 25003952 | J Hepatol | Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo. | 2014 | Details |
| A21853 | 24998970 | Toxicol Appl Pharmacol | Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease. | 2014 | Details |
| A21854 | 24998389 | Sci Rep | Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model. | 2014 | Details |
| A21856 | 24997224 | Exp Mol Pathol | TLR3/4 signaling is mediated via the NFκB-CXCR4/7 pathway in human alcoholic hepatitis and non-alcoholic steatohepatitis which formed Mallory-Denk bodies. | 2014 | Details |
| A21857 | 24995693 | Hepatology | The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice. | 2014 | Details |
| A21860 | 24993341 | Int Immunopharmacol | Involvement of hepatic peroxisome proliferator-activated receptor α/γ in the therapeutic effect of osthole on high-fat and high-sucrose-induced steatohepatitis in rats. | 2014 | Details |
| A21877 | 24985011 | Nutrition | Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation. | 2013 | Details |
| A21879 | 24983359 | PLoS One | L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway. | 2014 | Details |
| A21908 | 24968737 | Endocrine | Does vitamin D improve liver enzymes, oxidative stress, and inflammatory biomarkers in adults with non-alcoholic fatty liver disease? A randomized clinical trial. | 2014 | Details |
| A21910 | 24967351 | Biomed Res Int | Enhanced amelioration of high-fat diet-induced fatty liver by docosahexaenoic acid and lysine supplementations. | 2014 | Details |
| A21912 | 24966608 | World J Gastroenterol | Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease. | 2014 | Details |
| A21913 | 24966607 | World J Gastroenterol | Effects of resveratrol and other polyphenols in hepatic steatosis. | 2014 | Details |
| A21923 | 24963148 | EMBO Mol Med | A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis. | 2014 | Details |
| A21924 | 24962805 | Diabetes Obes Metab | Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis. | 2014 | Details |
| A21930 | 24958099 | Mol Cell Biol | Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance. | 2014 | Details |
| A21948 | 24944898 | Mol Metab | Osteopontin: A novel regulator at the cross roads of inflammation, obesity and diabetes. | 2014 | Details |
| A21967 | 24927058 | Expert Rev Mol Diagn | Plasma high mobility group box 1 protein reflects fibrosis in pediatric nonalcoholic fatty liver disease. | 2014 | Details |
| A21983 | 24916323 | BMC Gastroenterol | Chronic stress induces steatohepatitis while decreases visceral fat mass in mice. | 2014 | Details |
| A21986 | 24913135 | J Cell Mol Med | Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steatosis in mice. | 2014 | Details |
| A21994 | 24904182 | Angiology | Association between nonalcoholic fatty liver disease and carotid artery inflammation evaluated by 18F-fluorodeoxyglucose positron emission tomography. | 2014 | Details |
| A21998 | 24901254 | PLoS One | Cholesterol-induced non-alcoholic fatty liver disease and atherosclerosis aggravated by systemic inflammation. | 2014 | Details |
| A22003 | 24899308 | Nature | The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. | 2014 | Details |
| A22005 | 24898917 | Histopathology | Hepatocellular carcinoma with steatohepatitic features: a clinicopathological study of Japanese patients. | 2014 | Details |
| A22021 | 24875360 | Biochem Biophys Res Commun | Activation of farnesoid X receptor (FXR) protects against fructose-induced liver steatosis via inflammatory inhibition and ADRP reduction. | 2014 | Details |
| A22032 | 24864249 | Biomed Res Int | Endocannabinoid receptors gene expression in morbidly obese women with nonalcoholic fatty liver disease. | 2014 | Details |
| A22034 | 24861470 | Environ Toxicol | Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyls on nonalcoholic fatty liver disease in mice. | 2014 | Details |
| A22036 | 24861026 | J Mol Med (Berl) | NLRP3 inflammasome activation is required for fibrosis development in NAFLD. | 2014 | Details |
| A22038 | 24858832 | PLoS One | β-Cryptoxanthin alleviates diet-induced nonalcoholic steatohepatitis by suppressing inflammatory gene expression in mice. | 2014 | Details |
| A22040 | 24857364 | J Agric Food Chem | Garlic essential oil protects against obesity-triggered nonalcoholic fatty liver disease through modulation of lipid metabolism and oxidative stress. | 2014 | Details |
| A22043 | 24854865 | FEBS J | Overexpression of juxtaposed with another zinc finger gene 1 reduces proinflammatory cytokine release via inhibition of stress-activated protein kinases and nuclear factor-κB. | 2014 | Details |
| A22049 | 24850609 | Georgian Med News | [Effect of gene polymorphism of PPARgamma2 regulatory proteins on the metabolic syndrome in children with nonalcoholic fatty liver disease and obesity]. | 2014 | Details |
| A22054 | 24849253 | PLoS One | Deletion of nardilysin prevents the development of steatohepatitis and liver fibrotic changes. | 2014 | Details |
| A22058 | 24847614 | Cent Eur J Public Health | Gamma-glutamyl transpeptidase level associated with metabolic syndrome and proinflammatory parameters in the young Roma population in eastern Slovakia: a population-based study. | 2014 | Details |
| A22063 | 24845056 | Hepatology | Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation. | 2014 | Details |
| A22070 | 24841999 | Food Funct | Persimmon tannin accounts for hypolipidemic effects of persimmon through activating of AMPK and suppressing NF-κB activation and inflammatory responses in high-fat diet rats. | 2014 | Details |
| A22083 | 24830559 | Int J Mol Sci | Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation. | 2014 | Details |
| A22088 | 24829682 | Middle East J Dig Dis | Probiotics and Nonalcoholic Fatty liver Disease. | 2013 | Details |
| A22103 | 24819229 | Metab Syndr Relat Disord | Interrelationships of serum androgens, omental adipose tissue metabolism, and nonalcoholic fatty liver disease in obese premenopausal women. | 2014 | Details |
| A22107 | 24816278 | PLoS One | Lactoferrin dampens high-fructose corn syrup-induced hepatic manifestations of the metabolic syndrome in a murine model. | 2014 | Details |
| A22123 | 24799987 | World J Hepatol | Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease. | 2014 | Details |
| A22130 | 24797416 | Sci Rep | Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota. | 2014 | Details |
| A22135 | 24795720 | Front Immunol | Role of innate immune response in non-alcoholic Fatty liver disease: metabolic complications and therapeutic tools. | 2014 | Details |
| A22138 | 24795036 | Dig Dis Sci | Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet-induced NASH model. | 2014 | Details |
| A22142 | 24793347 | J Clin Lipidol | Association of nonalcoholic fatty liver disease with cardiovascular risk factors in obese adolescents: the role of interdisciplinary therapy. | 2014 | Details |
| A22149 | 24786317 | Exp Cell Res | Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model. | 2014 | Details |
| A22154 | 24784707 | Mol Cell Endocrinol | Resolvin D1 reduces ER stress-induced apoptosis and triglyceride accumulation through JNK pathway in HepG2 cells. | 2014 | Details |
| A22155 | 24783906 | Med Arch | Anthropometric and biochemical characteristics of patients with nonalcoholic fatty liver diagnosed by non-invasive diagnostic methods. | 2014 | Details |
| A22160 | 24781986 | PLoS One | Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice. | 2014 | Details |
| A22176 | 24766298 | Expert Opin Drug Discov | Evolving therapies for non-alcoholic steatohepatitis. | 2014 | Details |
| A22185 | 24760992 | Am J Physiol Endocrinol Metab | Mice lacking NOX2 are hyperphagic and store fat preferentially in the liver. | 2014 | Details |
| A22214 | 24745923 | Curr Pharm Des | Psoriasis and Vascular Risk : An Update. | 2014 | Details |
| A22218 | 24743504 | Eur J Gastroenterol Hepatol | Pentoxifylline for the treatment of nonalcoholic fatty liver disease: a meta-analysis of randomized double-blind, placebo-controlled studies. | 2014 | Details |
| A22220 | 24743120 | Georgian Med News | [Mechanisms of formation and progression of non-alcoholic fatty liver disease in type 2 diabetics]. | 2014 | Details |
| A22222 | 24742471 | J Nutr Biochem | Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases. | 2014 | Details |
| A22223 | 24741401 | Nutr Res Pract | Cordyceps militaris alleviates non-alcoholic fatty liver disease in ob/ob mice. | 2014 | Details |
| A22225 | 24740873 | Exp Biol Med (Maywood) | Emodin attenuates systemic and liver inflammation in hyperlipidemic mice administrated with lipopolysaccharides. | 2014 | Details |
| A22239 | 24731656 | Lancet Diabetes Endocrinol | Effects of iron overload on chronic metabolic diseases. | 2013 | Details |
| A22241 | 24729784 | Gastroenterol Res Pract | Chronic kidney disease and nonalcoholic Fatty liver disease-is there a link? | 2014 | Details |
| A22254 | 24716593 | BMC Gastroenterol | Expression of energy metabolism related genes in the gastric tissue of obese individuals with non-alcoholic fatty liver disease. | 2014 | Details |
| A22257 | 24715054 | Neurol Sci | The association between seizure predisposition and inflammation in a rat model of fatty liver disease. | 2014 | Details |
| A22258 | 24714086 | Int J Mol Sci | Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma. | 2014 | Details |
| A22268 | 24704474 | Biochem Pharmacol | Chrysin attenuates inflammation by regulating M1/M2 status via activating PPARγ. | 2014 | Details |
| A22278 | 24695736 | J Biol Chem | Deficiency of oncostatin M receptor β (OSMRβ) exacerbates high-fat diet-induced obesity and related metabolic disorders in mice. | 2014 | Details |
| A22287 | 24689911 | Metab Syndr Relat Disord | Regular exercise coupled to diet regimen accelerates reduction of hepatic steatosis and associated pathological conditions in nonalcoholic fatty liver disease. | 2014 | Details |
| A22317 | 24668763 | Hepatology | Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A22327 | 24657938 | PLoS One | Non-alcoholic fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms. | 2014 | Details |
| A22334 | 24653580 | Afr J Tradit Complement Altern Med | p38 MAPK signal pathway involved in anti-inflammatory effect of Chaihu-Shugan-San and Shen-ling-bai-zhu-San on hepatocyte in non-alcoholic steatohepatitis rats. | 2013 | Details |
| A22346 | 24649857 | Liver Int | Hepatic toll-like receptor 4 expression is associated with portal inflammation and fibrosis in patients with NAFLD. | 2014 | Details |
| A22360 | 24638078 | PLoS One | Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity. | 2014 | Details |
| A22369 | 24634500 | J Lipid Res | c9,t11-Conjugated linoleic acid ameliorates steatosis by modulating mitochondrial uncoupling and Nrf2 pathway. | 2014 | Details |
| A22380 | 24629563 | Metabolism | Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation. | 2014 | Details |
| A22381 | 24629059 | Obes Rev | Lysosomal cholesterol accumulation: driver on the road to inflammation during atherosclerosis and non-alcoholic steatohepatitis. | 2014 | Details |
| A22392 | 24622832 | J Physiol Pharmacol | Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up. | 2014 | Details |
| A22400 | 24616207 | Obesity (Silver Spring) | Macrophages and fibrosis in adipose tissue are linked to liver damage and metabolic risk in obese children. | 2014 | Details |
| A22409 | 24605611 | Lik Sprava | [Effect of probiotics on proinflammatory cytokines level in patients with type 2 diabetes and nonalcoholic fatty liver disease]. | 2013 | Details |
| A22412 | 24604574 | Eur J Nutr | The impact of cereal grain consumption on the development and severity of non-alcoholic fatty liver disease. | 2014 | Details |
| A22413 | 24604038 | Indian J Med Res | Probiotic foods: can their increasing use in India ameliorate the burden of chronic lifestyle disorders? | 2014 | Details |
| A22423 | 24587847 | Hepatol Int | Immune and inflammatory pathways in NASH. | 2013 | Details |
| A22424 | 24587658 | World J Gastroenterol | Diet high in fructose leads to an overexpression of lipocalin-2 in rat fatty liver. | 2014 | Details |
| A22428 | 24587651 | World J Gastroenterol | Risk of cardiovascular, cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease. | 2014 | Details |
| A22447 | 24566933 | Lab Invest | Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation. | 2014 | Details |
| A22475 | 24530600 | Clin Gastroenterol Hepatol | Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis. | 2014 | Details |
| A22476 | 24529605 | J Crohns Colitis | Detection of liver injury in IBD using transient elastography. | 2014 | Details |
| A22479 | 24528352 | Nutr Hosp | [Hepatic steatosis as diabetes type 2 predictor]. | 2014 | Details |
| A22489 | 24520264 | Exp Ther Med | Comparison between the efficacies of curcumin and puerarin in C57BL/6 mice with steatohepatitis induced by a methionine- and choline-deficient diet. | 2013 | Details |
| A22509 | 24505350 | PLoS One | Role of docosahexaenoic acid treatment in improving liver histology in pediatric nonalcoholic fatty liver disease. | 2014 | Details |
| A22512 | 24500395 | Eur J Pediatr | Serum hepcidin levels and iron metabolism in obese children with and without fatty liver: case-control study. | 2014 | Details |
| A22521 | 24492979 | Surg Today | Hydrolyzed whey peptide-based diet ameliorates hepatic ischemia-reperfusion injury in the rat nonalcoholic fatty liver. | 2014 | Details |
| A22526 | 24490861 | Br J Pharmacol | Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration. | 2014 | Details |
| A22530 | 24489722 | PLoS One | Cigarette smoke toxins deposited on surfaces: implications for human health. | 2014 | Details |
| A22534 | 24486145 | Diabetes Metab | Adiponectin: A multitasking player in the field of liver diseases. | 2014 | Details |
| A22547 | 24474231 | Arq Gastroenterol | Nonalcoholic fatty liver disease in severe obese patients, subjected to bariatric surgery. | 2014 | Details |
| A22554 | 24465369 | PLoS One | Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding. | 2014 | Details |
| A22565 | 24460502 | Gynecol Endocrinol | Nonalcoholic fatty liver disease and metabolic syndrome in postmenopausal women. | 2014 | Details |
| A22583 | 24445049 | J Nutr Biochem | Sesame oil mitigates nutritional steatohepatitis via attenuation of oxidative stress and inflammation: a tale of two-hit hypothesis. | 2013 | Details |
| A22584 | 24445047 | J Nutr Biochem | Role of immunodeficient animal models in the development of fructose induced NAFLD. | 2013 | Details |
| A22587 | 24442146 | Acta Pharmacol Sin | Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats. | 2014 | Details |
| A22598 | 24428677 | Expert Opin Pharmacother | New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease. | 2014 | Details |
| A22599 | 24426199 | Indian J Clin Biochem | Efficacy of Tumor Necrosis Factor and Interleukin-10 Analysis in the Follow-up of Nonalcoholic Fatty Liver Disease Progression. | 2012 | Details |
| A22607 | 24417951 | Best Pract Res Clin Endocrinol Metab | Adiponectin as a routine clinical biomarker. | 2013 | Details |