Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A47244 | 21645218 | Liver Int | Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts. | 2011 | Details |
| A47245 | 21633659 | World J Gastroenterol | Hepatic stellate cells and innate immunity in alcoholic liver disease. | 2011 | Details |
| A47246 | 21535024 | Alcohol Clin Exp Res | Chronic ethanol consumption in mice alters hepatocyte lipid droplet properties. | 2011 | Details |
| A47247 | 21519326 | Lab Invest | The nuclear receptor CAR modulates alcohol-induced liver injury. | 2011 | Details |
| A47248 | 21457226 | Br J Pharmacol | The endocannabinoid system as a key mediator during liver diseases: new insights and therapeutic openings. | 2011 | Details |
| A47249 | 21423135 | Lab Invest | Fructose-induced steatosis in mice: role of plasminogen activator inhibitor-1, microsomal triglyceride transfer protein and NKT cells. | 2011 | Details |
| A47250 | 21414374 | Food Chem Toxicol | Herbal formula CGX ameliorates LPS/D-galactosamine-induced hepatitis. | 2011 | Details |
| A47251 | 21401100 | J Agric Food Chem | Effects of Antrodia camphorata on alcohol clearance and antifibrosis in livers of rats continuously fed alcohol. | 2011 | Details |
| A47252 | 21386907 | PLoS One | Hepatic deletion of Smad7 in mouse leads to spontaneous liver dysfunction and aggravates alcoholic liver injury. | 2011 | Details |
| A47253 | 21334404 | J Hepatol | Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease. | 2011 | Details |
| A47254 | 21254164 | Hepatology | Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. | 2010 | Details |
| A47255 | 21105651 | J Agric Food Chem | Gentiana manshurica Kitagawa reverses acute alcohol-induced liver steatosis through blocking sterol regulatory element-binding protein-1 maturation. | 2010 | Details |
| A47256 | 21087523 | J Transl Med | Exploring the molecular mechanisms underlying the potentiation of exogenous growth hormone on alcohol-induced fatty liver diseases in mice. | 2010 | Details |
| A47257 | 20981870 | Phytother Res | Osthole improves alcohol-induced fatty liver in mice by reduction of hepatic oxidative stress. | 2010 | Details |
| A47258 | 20955970 | Best Pract Res Clin Gastroenterol | Alcoholic steatohepatitis. | 2010 | Details |
| A47259 | 20739640 | J Lipid Res | Involvement and mechanism of DGAT2 upregulation in the pathogenesis of alcoholic fatty liver disease. | 2010 | Details |
| A47260 | 20659474 | Gastroenterology | Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice. | 2010 | Details |
| A47261 | 20399524 | J Hepatol | Harmful effect of adipose tissue on liver lesions in patients with alcoholic liver disease. | 2010 | Details |
| A47262 | 20192205 | J Agric Food Chem | Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage. | 2010 | Details |
| A47263 | 20180235 | World J Gastroenterol | Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis. | 2010 | Details |
| A47264 | 20171585 | J Chin Med Assoc | Serum interleukin-12 levels in alcoholic liver disease. | 2010 | Details |
| A47265 | 20042322 | Phytomedicine | Osthol regulates hepatic PPAR alpha-mediated lipogenic gene expression in alcoholic fatty liver murine. | 2009 | Details |
| A47266 | 20041784 | J Med Food | Protective effect of Codonopsis lanceolata root extract against alcoholic fatty liver in the rat. | 2009 | Details |
| A47267 | 19958646 | Zhonghua Gan Zang Bing Za Zhi | [Magnesium isoglycyrrhizinate in the treatment of chronic liver diseases: a randomized, double-blind, multi-doses, active drug controlled, multi-center study]. | 2009 | Details |
| A47268 | 19912698 | Zhonghua Gan Zang Bing Za Zhi | [Study on the mechanism of preventing alcholic liver disease by selective cyclooxygenase 2 inhibitor]. | 2009 | Details |
| A47269 | 19714808 | J Proteome Res | Liver proteome analysis in a rodent model of alcoholic steatosis. | 2009 | Details |
| A47270 | 19696551 | Korean J Gastroenterol | [Sialadenosis in a patient with alcoholic fatty liver developing after heavy alcohol drinking]. | 2009 | Details |
| A47271 | 19683027 | Food Chem Toxicol | Protective effects of saponins from the root of Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the activation of AMP-dependent protein kinase. | 2009 | Details |
| A47272 | 19645734 | Alcohol Clin Exp Res | Current experimental perspectives on the clinical progression of alcoholic liver disease. | 2009 | Details |
| A47273 | 19645728 | Alcohol Clin Exp Res | Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats. | 2009 | Details |
| A47274 | 19637192 | Hepatology | Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. | 2009 | Details |
| A47275 | 19608736 | Am J Physiol Gastrointest Liver Physiol | Pathological roles of bone marrow-derived stellate cells in a mouse model of alcohol-induced fatty liver. | 2009 | Details |
| A47276 | 19606259 | J Biomed Biotechnol | Curcumin decreased oxidative stress, inhibited NF-kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats. | 2009 | Details |
| A47277 | 19588123 | Arch Toxicol | Ethanol and liver: recent advances in the mechanisms of ethanol-induced hepatosteatosis. | 2009 | Details |
| A47278 | 19372631 | J Pharmacol Sci | Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c. | 2009 | Details |
| A47279 | 19371623 | Toxicol Appl Pharmacol | Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes. | 2009 | Details |
| A47280 | 19285261 | Best Pract Res Clin Endocrinol Metab | The role of the endocannabinoid system in liver diseases. | 2009 | Details |
| A47281 | 19239162 | Adv Exp Med Biol | Effect of taurine on alcoholic liver disease in rats. | 2009 | Details |
| A47282 | 19221436 | J Clin Invest | Adenosine signaling contributes to ethanol-induced fatty liver in mice. | 2009 | Details |
| A47283 | 19208340 | Gastroenterology | Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1. | 2009 | Details |
| A47284 | 19170661 | Alcohol Clin Exp Res | Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease. | 2009 | Details |
| A47285 | 19157621 | J Hepatol | The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model. | 2008 | Details |
| A47286 | 19109846 | Liver Transpl | Impact of donor graft steatosis on overall outcome and viral recurrence after liver transplantation for hepatitis C virus cirrhosis. | 2009 | Details |
| A47287 | 19032866 | Zhonghua Gan Zang Bing Za Zhi | [An experimental study on the relationship between proteasome LMP7 subunit and alcoholic liver disease]. | 2008 | Details |
| A47288 | 19013495 | Food Chem Toxicol | Salvia miltiorrhiza Bunge and its active component cryptotanshinone protects primary cultured rat hepatocytes from acute ethanol-induced cytotoxicity and fatty infiltration. | 2008 | Details |
| A47289 | 19011575 | Eur J Gastroenterol Hepatol | The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption. | 2009 | Details |
| A47290 | 19003881 | Hepatology | Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms. | 2008 | Details |
| A47291 | 18778724 | Toxicol Appl Pharmacol | Interaction of osteopontin with neutrophil alpha(4)beta(1) and alpha(9)beta(1) integrins in a rodent model of alcoholic liver disease. | 2008 | Details |
| A47292 | 18722787 | Cytokine | Fat diet and alcohol-induced steatohepatitis after LPS challenge in mice: role of bioactive TNF and Th1 type cytokines. | 2008 | Details |
| A47293 | 18693172 | Hepatobiliary Pancreat Dis Int | Epidemiology of fatty liver in an islander population of China: a population-based case-control study. | 2008 | Details |
| A47294 | 18599584 | Am J Physiol Gastrointest Liver Physiol | Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis. | 2008 | Details |
| A47295 | 18599023 | Biochem Pharmacol | An in vitro method of alcoholic liver injury using precision-cut liver slices from rats. | 2008 | Details |
| A47296 | 18541827 | Arch Intern Med | Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial. | 2008 | Details |
| A47297 | 18534708 | Diabetes Res Clin Pract | Fatty liver and chronic inflammation in Chinese adults. | 2008 | Details |
| A47298 | 18509591 | Amino Acids | Effect of taurine on alcoholic liver disease in rats. | 2008 | Details |
| A47299 | 18498552 | Alcohol Clin Exp Res | Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver. | 2008 | Details |
| A47300 | 18481025 | Arch Pharm Res | Effects of tanshinone IIA on the hepatotoxicity and gene expression involved in alcoholic liver disease. | 2008 | Details |
| A47301 | 18336673 | J Gastroenterol Hepatol | Cholesterol and sphingolipids in alcohol-induced liver injury. | 2008 | Details |
| A47302 | 18395093 | Gastroenterology | Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury. | 2008 | Details |
| A47303 | 18369908 | Methods Mol Biol | A voluntary oral-feeding rat model for pathological alcoholic liver injury. | 2008 | Details |
| A47304 | 18341647 | Alcohol Clin Exp Res | A voluntary oral ethanol-feeding rat model associated with necroinflammatory liver injury. | 2008 | Details |
| A47305 | 18339590 | Dig Liver Dis | Inhibitory effect of osthole on alcohol-induced fatty liver in mice. | 2008 | Details |
| A47306 | 18337117 | Cytokine | Evaluation of the transforming growth factor beta1 codon 25 (Arg-->Pro) polymorphism in alcoholic liver disease. | 2008 | Details |
| A47307 | 18049163 | Eur J Gastroenterol Hepatol | Association of CTLA4 single nucleotide polymorphisms with viral but not autoimmune liver disease. | 2007 | Details |
| A47308 | 17767876 | Zhonghua Yu Fang Yi Xue Za Zhi | [A cross-sectional study on liver diseases in the rural residents in southern Guangxi, China]. | 2007 | Details |
| A47309 | 17850215 | Alcohol Clin Exp Res | Lysosomal leakage and lack of adaptation of hepatoprotective enzyme contribute to enhanced susceptibility to ethanol-induced liver injury in female rats. | 2007 | Details |
| A47310 | 17681030 | Alcohol Clin Exp Res | Thymocytes, pre-B cells, and organ changes in a mouse model of chronic ethanol ingestion--absence of subset-specific glucocorticoid-induced immune cell loss. | 2007 | Details |
| A47311 | 17655900 | Toxicol Appl Pharmacol | Differential gene expression and lipid metabolism in fatty liver induced by acute ethanol treatment in mice. | 2007 | Details |
| A47312 | 17616758 | Am J Clin Nutr | Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium. | 2007 | Details |
| A47313 | 17544978 | Clin Liver Dis | Steatosis as a cofactor in other liver diseases: hepatitis C virus, alcohol, hemochromatosis, and others. | 2007 | Details |
| A47314 | 17453353 | Cell Biol Toxicol | Fenugreek seed (Trigonella foenum graecum) polyphenols inhibit ethanol-induced collagen and lipid accumulation in rat liver. | 2007 | Details |
| A47315 | 17361525 | Chin J Integr Med | Intervention effects of Jianpi Liqi Huoxue Decoction on lipid peroxidative liver injury induced by alcohol. | 2006 | Details |
| A47316 | 17328242 | Arch Pharm Res | Altered activity of cytochrome P450 in alcoholic fatty liver exposed to ischemia/reperfusion. | 2007 | Details |
| A47317 | 17307722 | Am J Physiol Gastrointest Liver Physiol | Proteomic analysis of hepatic iron overload in mice suggests dysregulation of urea cycle, impairment of fatty acid oxidation, and changes in the methylation cycle. | 2007 | Details |
| A47318 | 17255218 | Gut | Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease. | 2007 | Details |
| A47319 | 17203086 | Nat Clin Pract Gastroenterol Hepatol | Management strategies in alcoholic liver disease. | 2007 | Details |
| A47320 | 17133459 | Hepatology | Genomics and complex liver disease: Challenges and opportunities. | 2006 | Details |
| A47321 | 17105587 | Liver Int | Serum levels of cytokeratin-18 (tissue polypeptide-specific antigen) in liver diseases. | 2006 | Details |
| A47322 | 17090375 | Zhong Xi Yi Jie He Xue Bao | [Preparation of Lieber-DeCarli liquid diet induced alcoholic hepatic injury model in rats]. | 2006 | Details |
| A47323 | 17058832 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Relationship between alcoholic liver injury and endotoxin leakage from gut and intervention effect of jianpi liqi huoxue decoction]. | 2006 | Details |
| A47324 | 17031051 | Biosci Biotechnol Biochem | Sake yeast suppresses acute alcohol-induced liver injury in mice. | 2006 | Details |
| A47325 | 16980711 | Alcohol Alcohol | The total body mass of fatty acid ethyl esters in skeletal muscles following ethanol exposure greatly exceeds that found in the liver and the heart. | 2006 | Details |
| A47326 | 16958678 | J Gastroenterol Hepatol | Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum. | 2006 | Details |
| A47327 | 16958658 | J Gastroenterol Hepatol | Anti-adipogenic regulation underlies hepatic stellate cell transdifferentiation. | 2006 | Details |
| A47328 | 16696916 | Zhong Xi Yi Jie He Xue Bao | [Establishment of a rat model of alcoholic liver fibrosis induced by complex factors]. | 2006 | Details |
| A47329 | 16641879 | Med Sci Monit | Interleukin-8 in the blood serum of patients with alcoholic liver disease. | 2006 | Details |
| A47330 | 16580087 | J Hepatol | The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease. | 2006 | Details |
| A47331 | 16462037 | Biol Pharm Bull | Glycoprotein isolated from Acanthopanax senticosus protects against hepatotoxicity induced by acute and chronic alcohol treatment. | 2006 | Details |
| A47332 | 16440289 | J Pathol | Higher neutrophil infiltration mediated by osteopontin is a likely contributing factor to the increased susceptibility of females to alcoholic liver disease. | 2006 | Details |
| A47333 | 16439473 | Am J Physiol Gastrointest Liver Physiol | Involvement of Toll-like receptor 4 in acetaminophen hepatotoxicity. | 2006 | Details |
| A47334 | 16344062 | Gastroenterology | Steatosis is a cofactor in liver injury in hemochromatosis. | 2005 | Details |
| A47335 | 16227360 | Gut | Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake. | 2005 | Details |
| A47336 | 16170395 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | High adiponectin and TNF-alpha levels in moderate drinkers suffering from liver steatosis: comparison with non drinkers suffering from similar hepatopathy. | 2005 | Details |
| A47337 | 16115302 | J Intern Med | Circulating adiponectin reflects severity of liver disease but not insulin sensitivity in liver cirrhosis. | 2005 | Details |
| A47338 | 15894299 | Clin Chim Acta | Fatty acid methyl esters are detectable in the plasma and their presence correlates with liver dysfunction. | 2005 | Details |
| A47339 | 15885730 | Toxicol Appl Pharmacol | Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis. | 2005 | Details |
| A47340 | 15826726 | J Hepatol | Hepatic phospholipids in alcoholic liver disease assessed by proton-decoupled 31P magnetic resonance spectroscopy. | 2005 | Details |
| A47341 | 15674092 | Eur J Gastroenterol Hepatol | Correlation of alcohol consumption with liver histological features in non-cirrhotic patients. | 2005 | Details |
| A47342 | 15603541 | Toxicol Pathol | Hepatocyte proliferation is the possible mechanism for the transient decrease in liver injury during steatosis stage of alcoholic liver disease. | 2005 | Details |
| A47343 | 15519643 | J Hepatol | Polyunsaturated fatty acid deficiency reverses effects of alcohol on mitochondrial energy metabolism. | 2004 | Details |