Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A16245 | 28486193 | Biomed Pharmacother | Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro. | 2017 | Details |
| A16247 | 28484247 | Sci Rep | Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota. | 2017 | Details |
| A16253 | 28483554 | Biochim Biophys Acta Mol Cell Biol Lipids | Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. | 2017 | Details |
| A16259 | 28481357 | Nat Med | Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4. | 2017 | Details |
| A16267 | 28478385 | J Biol Chem | Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism. | 2017 | Details |
| A16268 | 28476236 | Endocrinol Metab Clin North Am | Genetics of Lipodystrophy. | 2017 | Details |
| A16269 | 28475150 | Int J Mol Sci | Reply to the Letter to the Editor by Li et al.: Bioinformatics Analysis in Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E. | 2017 | Details |
| A16275 | 28472948 | BMC Gastroenterol | Noninvasive assessment of liver steatosis in children: the clinical value of controlled attenuation parameter. | 2017 | Details |
| A16280 | 28471945 | AIDS | Metabolic concerns in aging HIV-infected persons: from serum lipid phenotype to fatty liver. | 2017 | Details |
| A16283 | 28471823 | Eur J Gastroenterol Hepatol | The effects of diet and lifestyle interventions on insulin resistance in patients with nonalcoholic fatty liver disease: a systematic review. | 2017 | Details |
| A16284 | 28471821 | Eur J Gastroenterol Hepatol | Diabetic status and grade of nonalcoholic fatty liver disease are associated with lower baroreceptor sensitivity in patients with nonalcoholic fatty liver disease. | 2017 | Details |
| A16300 | 28468951 | Clin Sci (Lond) | Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease. | 2017 | Details |
| A16301 | 28468933 | J Endocrinol | The metabolic syndrome in mice overexpressing neuropeptide Y in noradrenergic neurons. | 2017 | Details |
| A16315 | 28463404 | Mol Nutr Food Res | A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota. | 2017 | Details |
| A16316 | 28462811 | Trends Endocrinol Metab | Sphingolipids and Lipoproteins in Health and Metabolic Disorders. | 2017 | Details |
| A16319 | 28461774 | Korean J Physiol Pharmacol | Endogenous catalase delays high-fat diet-induced liver injury in mice. | 2017 | Details |
| A16320 | 28461687 | Int J Obes (Lond) | Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in non-alcoholic fatty liver disease. | 2017 | Details |
| A16321 | 28460349 | Cancer Epidemiol | Nonalcoholic fatty liver disease and mortality among cancer survivors. | 2017 | Details |
| A16324 | 28458689 | Int J Endocrinol | Nonalcoholic Fatty Liver Disease and Associated Metabolic Risks of Hypertension in Type 2 Diabetes: A Cross-Sectional Community-Based Study. | 2017 | Details |
| A16336 | 28452101 | Diabetes Obes Metab | Effects of combined low-dose spironolactone plus vitamin E vs vitamin E monotherapy on insulin resistance, non-invasive indices of steatosis and fibrosis, and adipokine levels in non-alcoholic fatty liver disease: a randomized controlled trial. | 2017 | Details |
| A16342 | 28446519 | Diabetes | Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia. | 2017 | Details |
| A16345 | 28445310 | Medicine (Baltimore) | Diagnostic accuracy of serum alanine aminotransferase as biomarker for nonalcoholic fatty liver disease and insulin resistance in healthy subjects, using 3T MR spectroscopy. | 2017 | Details |
| A16347 | 28445156 | Oncotarget | Dietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice. | 2017 | Details |
| A16348 | 28443804 | J Am Coll Nutr | 25(OH)D Levels in Relation to Gender, Overweight, Insulin Resistance, and Inflammation in a Cross-Sectional Cohort of Northern Italian Workers: Evidence in Support of Preventive Health Care Programs. | 2017 | Details |
| A16349 | 28443702 | J Am Coll Nutr | Turmeric Supplementation Improves Serum Glucose Indices and Leptin Levels in Patients with Nonalcoholic Fatty Liver Diseases. | 2017 | Details |
| A16352 | 28442507 | J Endocrinol | Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice. | 2017 | Details |
| A16364 | 28436456 | Sci Rep | Synthesis and anti-obesity effects in vivo of Crotadihydrofuran C as a novel PPARγ antagonist from Crotalaria albida. | 2017 | Details |
| A16366 | 28436198 | Mol Nutr Food Res | Effects of selenium on apoptosis and abnormal amino acid metabolism induced by excess fatty acid in isolated rat hepatocytes. | 2017 | Details |
| A16372 | 28430371 | APMIS | Evaluation of circulating zonulin as a potential marker in the pathogenesis of nonalcoholic fatty liver disease. | 2017 | Details |
| A16376 | 28428634 | Nat Rev Gastroenterol Hepatol | Lipid droplets and liver disease: from basic biology to clinical implications. | 2017 | Details |
| A16377 | 28428362 | J Endocrinol | Hepatic lipid accumulation: cause and consequence of dysregulated glucoregulatory hormones. | 2017 | Details |
| A16387 | 28425154 | Hepatol Res | Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study. | 2017 | Details |
| A16388 | 28424263 | J Biol Chem | The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. | 2017 | Details |
| A16394 | 28420094 | Nutrients | Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments. | 2017 | Details |
| A16401 | 28417532 | Diabetes Obes Metab | Non-alcoholic fatty liver disease (NAFLD) prevalence and its metabolic associations in patients with type 1 diabetes and type 2 diabetes. | 2017 | Details |
| A16407 | 28414056 | Eur J Pharmacol | Protective effects of glycyrrhizic acid against non-alcoholic fatty liver disease in mice. | 2017 | Details |
| A16411 | 28411267 | Diabetes | NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway. | 2017 | Details |
| A16412 | 28411170 | Biochim Biophys Acta Biomembr | The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease. | 2017 | Details |
| A16414 | 28406477 | Cell Death Dis | miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice. | 2017 | Details |
| A16423 | 28402022 | J Cell Biochem | Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice. | 2017 | Details |
| A16429 | 28395666 | Lipids Health Dis | Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice. | 2017 | Details |
| A16434 | 28392354 | Diabetes Metab Syndr | Lower circulating irisin is associated with nonalcoholic fatty liver disease and type 2 diabetes. | 2017 | Details |
| A16435 | 28391883 | J Clin Lipidol | Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases. | 2016 | Details |
| A16440 | 28387617 | J Med Food | Oral Administration of β-Glucosylceramide for the Treatment of Insulin Resistance and Nonalcoholic Steatohepatitis: Results of a Double-Blind, Placebo-Controlled Trial. | 2017 | Details |
| A16457 | 28376109 | PLoS One | Association of leukocyte cell-derived chemotaxin 2 (LECT2) with NAFLD, metabolic syndrome, and atherosclerosis. | 2017 | Details |
| A16460 | 28375109 | Pak J Pharm Sci | Anti hyperlipidemic and hepatoprotective effects of native date fruit variety "Aseel" (Phoenix dactylifera). | 2016 | Details |
| A16463 | 28373762 | World J Gastroenterol | Traditional Chinese herbal extracts inducing autophagy as a novel approach in therapy of nonalcoholic fatty liver disease. | 2017 | Details |
| A16465 | 28371475 | J Diabetes Investig | Impact of non-alcoholic fatty pancreas disease on glucose metabolism. | 2017 | Details |
| A16466 | 28371239 | Liver Int | The Mediterranean dietary pattern as the diet of choice for non-alcoholic fatty liver disease: Evidence and plausible mechanisms. | 2017 | Details |
| A16467 | 28370150 | Aliment Pharmacol Ther | Polycystic ovary syndrome with hyperandrogenism as a risk factor for non-obese non-alcoholic fatty liver disease. | 2017 | Details |
| A16477 | 28365930 | J BUON | Hepatocellular carcinoma development in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Is it going to be the "Plague" of the 21st century? A literature review focusing on pathogenesis, prevention and treatment. | 2017 | Details |
| A16478 | 28365312 | J Hepatol | Activating transcription factor 3 is a target molecule linking hepatic steatosis to impaired glucose homeostasis. | 2017 | Details |
| A16479 | 28364816 | Clin Liver Dis | De Novo and Recurrence of Nonalcoholic Steatohepatitis After Liver Transplantation. | 2017 | Details |
| A16489 | 28358620 | Metab Syndr Relat Disord | Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice. | 2017 | Details |
| A16498 | 28351752 | Exp Cell Res | Deficiency of CKIP-1 aggravates high-fat diet-induced fatty liver in mice. | 2017 | Details |
| A16503 | 28349245 | J Gastroenterol | Effect of miglitol on the suppression of nonalcoholic steatohepatitis development and improvement of the gut environment in a rodent model. | 2017 | Details |
| A16507 | 28348479 | World J Gastroenterol | Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle. | 2017 | Details |
| A16512 | 28346567 | J Nutr Health Aging | Effect of a Low Glycemic Index Mediterranean Diet on Non-Alcoholic Fatty Liver Disease. A Randomized Controlled Clinici Trial. | 2017 | Details |
| A16515 | 28346237 | Curr Opin Gastroenterol | Current and future pharmacologic treatment of nonalcoholic steatohepatitis. | 2017 | Details |
| A16520 | 28341541 | Mol Aspects Med | Pro-resolving actions of SPM in adipose tissue biology. | 2017 | Details |
| A16523 | 28338115 | J Gastrointestin Liver Dis | Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-analysis. | 2017 | Details |
| A16529 | 28334911 | Hum Mol Genet | MERTK rs4374383 variant predicts incident nonalcoholic fatty liver disease and diabetes: role of mononuclear cell activation and adipokine response to dietary fat. | 2017 | Details |
| A16532 | 28332619 | Sci Rep | Retinol Binding Protein-4 Levels and Non-alcoholic Fatty Liver Disease: A community-based cross-sectional study. | 2017 | Details |
| A16534 | 28330852 | FASEB J | A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice. | 2017 | Details |
| A16537 | 28327588 | Nat Commun | Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice. | 2017 | Details |
| A16539 | 28325853 | Diabetes | Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance Through ERα/HGF/Met Pathway. | 2017 | Details |
| A16541 | 28325476 | Arab J Gastroenterol | Erectile dysfunction in patients with nonalcoholic fatty liver disease. | 2017 | Details |
| A16543 | 28324110 | J Clin Endocrinol Metab | Effects of Metreleptin in Pediatric Patients With Lipodystrophy. | 2017 | Details |
| A16545 | 28323952 | J Clin Endocrinol Metab | Randomized Controlled Trial of a MUFA or Fiber-Rich Diet on Hepatic Fat in Prediabetes. | 2017 | Details |
| A16557 | 28318525 | Actas Dermosifiliogr | Psoriasis and Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16558 | 28318371 | Scand J Clin Lab Invest | P-selectin, endocan, and some adhesion molecules in obese children and adolescents with non-alcoholic fatty liver disease. | 2017 | Details |
| A16564 | 28306139 | Br J Pharmacol | The TIR/BB-loop mimetic AS-1 prevents non-alcoholic steatohepatitis and hepatic insulin resistance by inhibiting NLRP3-ASC inflammasome activation. | 2017 | Details |
| A16566 | 28303724 | Drug Metab Rev | Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. | 2017 | Details |
| A16568 | 28300221 | Sci Rep | Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats. | 2017 | Details |
| A16571 | 28299304 | Adv Biomed Res | Effects of Phlebotomy on Liver Enzymes and Histology of Patients with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16588 | 28297775 | Zhonghua Gan Zang Bing Za Zhi | [Effect of calcium-independent phospholipase A(2) inhibitor in reducing hepatocyte lipoapoptosis and improving insulin resistance]. | 2017 | Details |
| A16593 | 28294174 | Eur J Clin Nutr | Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study. | 2017 | Details |
| A16598 | 28291240 | Am J Gastroenterol | Testosterone Levels in Pre-Menopausal Women are Associated With Nonalcoholic Fatty Liver Disease in Midlife. | 2017 | Details |
| A16600 | 28290049 | Curr Diab Rep | Type 2 Diabetes and Hepatocellular Carcinoma: Risk Factors and Pathogenesis. | 2017 | Details |
| A16613 | 28283346 | Eur J Intern Med | Is HOMA-IR a potential screening test for non-alcoholic fatty liver disease in adults with type 2 diabetes? | 2017 | Details |
| A16615 | 28282659 | Horm Metab Res | Low Serum Sex Hormone-Binding Globulin Associated with Insulin Resistance in Men with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16618 | 28281515 | Ter Arkh | [Clinical and metabolic features of nonalcoholic fatty liver disease in men and women]. | 2017 | Details |
| A16620 | 28281237 | Obes Surg | Adipokine Levels Versus Hepatic Histopathology in Bariatric Surgery Patients. | 2017 | Details |
| A16624 | 28277977 | Epigenetics | Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action. | 2017 | Details |
| A16628 | 28276774 | Expert Rev Clin Pharmacol | Pharmacological management of nonalcoholic fatty liver disease in type 2 diabetes. | 2017 | Details |
| A16634 | 28273479 | Cell Metab | Systems Biology of Metabolism: A Driver for Developing Personalized and Precision Medicine. | 2017 | Details |
| A16637 | 28271033 | Mol Metab | Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis. | 2017 | Details |
| A16638 | 28271032 | Mol Metab | Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice. | 2017 | Details |
| A16639 | 28270882 | J Clin Med Res | Insulin-Like Growth Factor-1 Deficiency and Cirrhosis Establishment. | 2017 | Details |
| A16642 | 28270444 | Am J Physiol Endocrinol Metab | α-Linolenic acid supplementation and exercise training reveal independent and additive responses on hepatic lipid accumulation in obese rats. | 2017 | Details |
| A16651 | 28264657 | BMC Gastroenterol | "Non alcoholic fatty liver disease and eNOS dysfunction in humans". | 2017 | Details |
| A16656 | 28262196 | Arch Med Res | Serum Chemerin in Obese Children and Adolescents Before and After L-Carnitine Therapy: Relation to Nonalcoholic Fatty Liver Disease and Other Features of Metabolic Syndrome. | 2016 | Details |
| A16659 | 28260070 | Int J Mol Med | A long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, as a preventive drug for the development of hepatic steatosis in high-fructose diet-fed ob/ob mice. | 2017 | Details |
| A16669 | 28254666 | Biomed Pharmacother | Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c. | 2017 | Details |
| A16673 | 28253210 | Eur J Gastroenterol Hepatol | The association of nonalcoholic fatty liver disease with genetic polymorphisms: a multicenter study. | 2017 | Details |
| A16677 | 28250783 | J Res Med Sci | Do symbiotic and Vitamin E supplementation have favorite effects in nonalcoholic fatty liver disease? A randomized, double-blind, placebo-controlled trial. | 2016 | Details |
| A16679 | 28250290 | Intern Med | The Relationship between the Growth Hormone/Insulin-like Growth Factor System and the Histological Features of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16680 | 28249275 | Dig Dis | Intestinal Farnesoid X Receptor Signaling Modulates Metabolic Disease. | 2017 | Details |
| A16681 | 28249273 | Dig Dis | Intestinal Farnesoid X Receptor and Takeda G Protein Couple Receptor 5 Signaling in Metabolic Regulation. | 2017 | Details |
| A16686 | 28244519 | Food Funct | A diet containing a high- versus low-daidzein level does not protect against liver steatosis in the obese Zucker rat model. | 2017 | Details |