Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A12346 | 30498712 | Hepatobiliary Surg Nutr | New insights into genetic predisposition and novel therapeutic targets for nonalcoholic fatty liver disease. | 2018 | Details |
| A12347 | 30498378 | Hepat Med | Universal Index for Cirrhosis (UIC index): The development and validation of a novel index to predict advanced liver disease. | 2018 | Details |
| A12357 | 30488108 | Eur Radiol | Magnitude dependent discordance in liver stiffness measurements using elastography point quantification with transient elastography as the reference test. | 2018 | Details |
| A12358 | 30487694 | World J Gastroenterol | Promoting genetics in non-alcoholic fatty liver disease: Combined risk score through polymorphisms and clinical variables. | 2018 | Details |
| A12359 | 30487357 | Exp Anim | AIM-deficient mouse fed a high-trans fat, high-cholesterol diet: a new animal model for nonalcoholic fatty liver disease. | 2018 | Details |
| A12366 | 30483595 | JGH Open | Epidemiology of non-alcoholic fatty liver disease-related hepatocellular carcinoma and its implications. | 2018 | Details |
| A12368 | 30483564 | JGH Open | Non-alcoholic fatty liver disease in patients with autoimmune hepatitis. | 2018 | Details |
| A12370 | 30483546 | JGH Open | Serum ferritin as a non-invasive marker in the prediction of hepatic fibrosis among Egyptian patients with non-alcoholic fatty liver disease. | 2017 | Details |
| A12373 | 30482910 | Nat Rev Gastroenterol Hepatol | The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2019 | Details |
| A12377 | 30479664 | Therap Adv Gastroenterol | Advances and challenges in the management of advanced fibrosis in nonalcoholic steatohepatitis. | 2018 | Details |
| A12379 | 30477455 | BMC Endocr Disord | Treatment with PBI-4050 in patients with Alström syndrome: study protocol for a phase 2, single-Centre, single-arm, open-label trial. | 2018 | Details |
| A12384 | 30474288 | Obes Rev | Sarcopenia in patients with non-alcoholic fatty liver disease: is it a clinically significant entity? | 2018 | Details |
| A12391 | 30473026 | Life Sci | p53 as a double-edged sword in the progression of non-alcoholic fatty liver disease. | 2018 | Details |
| A12399 | 30471458 | Clin Gastroenterol Hepatol | Accuracy of Noninvasive Scoring Systems in Assessing Risk of Death and Liver-Related Endpoints in Patients With Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12402 | 30470823 | Oncogene | Indian Hedgehog links obesity to development of hepatocellular carcinoma. | 2018 | Details |
| A12403 | 30469392 | J Clin Med | Bidirectional Association between Nonalcoholic Fatty Liver Disease and Gallstone Disease: A Cohort Study. | 2018 | Details |
| A12407 | 30467936 | Pediatr Diabetes | Non-alcoholic fatty liver disease in pediatric type 2 diabetes: Metabolic and histologic characteristics in 38 subjects. | 2018 | Details |
| A12409 | 30467325 | Sci Rep | BET Inhibition Improves NASH and Liver Fibrosis. | 2018 | Details |
| A12411 | 30466676 | Med Clin North Am | The Future of Nonalcoholic Fatty Liver Disease Treatment. | 2018 | Details |
| A12413 | 30465867 | Magn Reson Imaging | Evaluation of hepatic function using dynamic contrast-enhanced magnetic resonance imaging in melanocortin 4 receptor-deficient mice as a model of nonalcoholic steatohepatitis. | 2018 | Details |
| A12417 | 30463916 | Sci Transl Med | Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis. | 2018 | Details |
| A12420 | 30461221 | J Diabetes Investig | Effects of canagliflozin on body composition and hepatic fat content in type 2 diabetes patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A12423 | 30459715 | Front Endocrinol (Lausanne) | Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD. | 2018 | Details |
| A12428 | 30458247 | Clin Gastroenterol Hepatol | Low-Normal Thyroid Function Is Associated With Advanced Fibrosis Among Adults in the United States. | 2018 | Details |
| A12430 | 30458048 | PLoS One | One-year weight management lowers lipopolysaccharide-binding protein and its implication in metainflammation and liver fibrosis. | 2018 | Details |
| A12442 | 30454829 | Clin Liver Dis | Will Studies in Nonalcoholic Steatohepatitis Help Manage Alcoholic Steatohepatitis? | 2019 | Details |
| A12445 | 30454647 | Cell | Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. | 2018 | Details |
| A12454 | 30448600 | Clin Gastroenterol Hepatol | Prevalence and Severity of Nonalcoholic Fatty Liver Disease Among Caregivers of Patients With Nonalcoholic Fatty Liver Disease Cirrhosis. | 2018 | Details |
| A12455 | 30448594 | Clin Gastroenterol Hepatol | Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12464 | 30444796 | Invest Radiol | Tomoelastography for the Evaluation of Pediatric Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12466 | 30444569 | Liver Int | Genetic determinants of steatosis and fibrosis progression in paediatric non-alcoholic fatty liver disease. | 2018 | Details |
| A12471 | 30441981 | Vnitr Lek | Future of pharmacological treatment of non-alcoholic steatohepatitis in terms of key pathophysiological mechanisms. | 2019 | Details |
| A12472 | 30440285 | Annu Int Conf IEEE Eng Med Biol Soc | Objective Liver Fibrosis Estimation from Shear Wave Elastography. | 2018 | Details |
| A12474 | 30431378 | Curr Med Res Opin | Severe nonalcoholic steatohepatitis and type 2 diabetes: liver histology after weight loss therapy in a randomized clinical trial. | 2018 | Details |
| A12475 | 30430908 | Br J Biomed Sci | The severity of NAFLD is associated with the risk of urolithiasis. | 2018 | Details |
| A12490 | 30425964 | Front Oncol | Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer. | 2018 | Details |
| A12496 | 30422676 | Am J Respir Crit Care Med | Obstructive Sleep Apnea, Hypoxia, and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12505 | 30415572 | Orv Hetil | [Non-alcoholic fatty liver disease - a summary and update based on the EASL-EASD-EASO Clinical Practice Guidelines of 2016]. | 2018 | Details |
| A12510 | 30414863 | J Hepatol | Non-alcoholic fatty liver disease - A global public health perspective. | 2018 | Details |
| A12514 | 30413050 | Pharmaceuticals (Basel) | Antidiabetic Drugs in NAFLD: The Accomplishment of Two Goals at Once? | 2018 | Details |
| A12519 | 30411703 | Turk J Gastroenterol | Screening for hepatic fibrosis and steatosis in Turkish patients with type 2 diabetes mellitus: A transient elastography study. | 2019 | Details |
| A12525 | 30411081 | Hepatol Commun | Serum Interleukin-8, Osteopontin, and Monocyte Chemoattractant Protein 1 Are Associated With Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12526 | 30410123 | Sci Rep | Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease. | 2018 | Details |
| A12529 | 30408605 | Contemp Clin Trials | European paediatric non-alcoholic fatty liver disease registry (EU-PNAFLD): Design and rationale. | 2018 | Details |
| A12532 | 30405618 | Front Immunol | Adapted Immune Responses of Myeloid-Derived Cells in Fatty Liver Disease. | 2018 | Details |
| A12537 | 30403744 | PLoS One | Comparison of FIB-4 and transient elastography in evaluating liver fibrosis of chronic hepatitis C subjects in community. | 2018 | Details |
| A12542 | 30401631 | Contemp Clin Trials | Methods to improve the noninvasive diagnosis and assessment of disease severity in children with suspected nonalcoholic fatty liver disease (NAFLD): Study design. | 2018 | Details |
| A12543 | 30400829 | BMC Gastroenterol | Hepatocellular carcinoma is the most common liver-related complication in patients with histopathologically-confirmed NAFLD in Japan. | 2018 | Details |
| A12544 | 30400736 | Gut Liver | Effects of Moderate Alcohol Drinking in Patients with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12546 | 30400205 | Int J Mol Sci | Reactive Oxygen Species Induces Lipid Droplet Accumulation in HepG2 Cells by Increasing Perilipin 2 Expression. | 2018 | Details |
| A12548 | 30399002 | Eur J Gastroenterol Hepatol | Short article: Association between liver fibrosis and hepatitis E seroprevalence among HIV-positive individuals in Nepal. | 2019 | Details |
| A12549 | 30398639 | Ann Intern Med | Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12552 | 30394678 | J Int AIDS Soc | Predictive factors associated with liver fibrosis and steatosis by transient elastography in patients with HIV mono-infection under long-term combined antiretroviral therapy. | 2018 | Details |
| A12562 | 30390263 | Adv Exp Med Biol | Sarcopenia in Liver Disease: Current Evidence and Issues to Be sResolved. | 2019 | Details |
| A12563 | 30389552 | J Hepatol | A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3'UTR. | 2018 | Details |
| A12567 | 30388378 | Can J Physiol Pharmacol | Histopathological and biochemical changes in the development of nonalcoholic fatty liver disease induced by high-sucrose diet at different times. | 2018 | Details |
| A12575 | 30383414 | Am J Physiol Gastrointest Liver Physiol | Lipid mediators of liver injury in nonalcoholic fatty liver disease. | 2018 | Details |
| A12576 | 30382148 | Sci Rep | Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model. | 2018 | Details |
| A12578 | 30380656 | Nutrients | Advanced Liver Fibrosis Is Independently Associated with Palmitic Acid and Insulin Levels in Patients with Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
| A12580 | 30379980 | Acta Biochim Biophys Sin (Shanghai) | Chronic intermittent hypoxia promotes the development of experimental non-alcoholic steatohepatitis by modulating Treg/Th17 differentiation. | 2018 | Details |
| A12581 | 30379862 | PLoS One | Altered hepatic genes related to retinol metabolism and plasma retinol in patients with non-alcoholic fatty liver disease. | 2018 | Details |
| A12587 | 30374976 | J Pathol | Does prenylation predict progression in NAFLD? | 2018 | Details |
| A12588 | 30374329 | Front Endocrinol (Lausanne) | Therapeutic Approaches to Nonalcoholic Fatty Liver Disease: Exercise Intervention and Related Mechanisms. | 2018 | Details |
| A12592 | 30372785 | Hepatology | Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis. | 2019 | Details |
| A12596 | 30369082 | J Diabetes Investig | Nicotinic alpha-7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non-alcoholic steatohepatitis. | 2018 | Details |
| A12602 | 30367792 | Horm Mol Biol Clin Investig | Hypothyroidism and nonalcoholic fatty liver disease - a chance association? | 2018 | Details |
| A12603 | 30367534 | Hepatol Res | Epidemiological survey of hemoglobin A1c and liver fibrosis in a general population with non-alcoholic fatty liver disease. | 2018 | Details |
| A12609 | 30365236 | Hepatol Res | Combining probiotics and an angiotensin-II type 1 receptor blocker has beneficial effects on hepatic fibrogenesis in a rat model of non-alcoholic steatohepatitis. | 2018 | Details |
| A12612 | 30364513 | J Med Life | The role of noninvasive tests and liver biopsy in the diagnosis of nonalcoholic fatty liver disease. | 2018 | Details |
| A12616 | 30363686 | Int J Hepatol | Relationship between Serum Cytokeratin-18, Control Attenuation Parameter, NAFLD Fibrosis Score, and Liver Steatosis in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12622 | 30360708 | Mini Rev Med Chem | Association between Vitamin D Levels and Nonalcoholic Fatty Liver Disease: Potential Confounding Variables. | 2019 | Details |
| A12631 | 30359371 | PLoS One | N-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed mice. | 2018 | Details |
| A12638 | 30356113 | Sci Rep | Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis. | 2018 | Details |
| A12639 | 30355853 | J Biomed Res | Non-alcoholic fatty liver disease: a narrative review of genetics. | 2018 | Details |
| A12642 | 30353552 | Aliment Pharmacol Ther | The effects of metabolic status on non-alcoholic fatty liver disease-related outcomes, beyond the presence of obesity. | 2018 | Details |
| A12643 | 30353055 | Am J Gastroenterol | Smoking and the Risk of Non-Alcoholic Fatty Liver Disease: A Cohort Study. | 2019 | Details |
| A12654 | 30345152 | Liver Res | Extracellular vesicles in non-alcoholic and alcoholic fatty liver diseases. | 2018 | Details |
| A12658 | 30343320 | Cell Mol Life Sci | Molecular pathways of nonalcoholic fatty liver disease development and progression. | 2018 | Details |
| A12661 | 30340810 | Nutr Res | A review of the pathogenic and therapeutic role of nutrition in pediatric nonalcoholic fatty liver disease. | 2018 | Details |
| A12665 | 30338118 | Obes Sci Pract | Efficacy of canagliflozin against nonalcoholic fatty liver disease: a prospective cohort study. | 2018 | Details |
| A12667 | 30337225 | Mol Metab | Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates. | 2018 | Details |
| A12671 | 30335697 | Transplantation | Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: Implications for Liver Transplantation. | 2019 | Details |
| A12676 | 30334263 | Aliment Pharmacol Ther | Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease. | 2018 | Details |
| A12682 | 30328907 | Acta Cir Bras | Oxidative stress on ischemia/reperfusion injury in mice with non-alcoholic hepatic steatosis or steatohepatitis. | 2018 | Details |
| A12683 | 30328321 | Yonsei Med J | S100A4 Gene is Crucial for Methionine-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice. | 2018 | Details |
| A12689 | 30326299 | Clin Gastroenterol Hepatol | Complete Resolution of Nonalcoholic Fatty Liver Disease After Bariatric Surgery: A Systematic Review and Meta-analysis. | 2018 | Details |
| A12691 | 30325458 | QJM | Non-alcoholic fatty liver disease and 30-day all-cause mortality in adult patients with community-acquired pneumonia. | 2019 | Details |
| A12701 | 30323112 | J Lipid Res | Splice variant rs72613567 prevents worst histologic outcomes in patients with nonalcoholic fatty liver disease. | 2018 | Details |
| A12702 | 30322964 | J Immunol | Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12712 | 30318268 | Psychosomatics | Psychosocial Issues in Pediatric Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12719 | 30316865 | EBioMedicine | Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice. | 2018 | Details |
| A12722 | 30315891 | Diabetes Metab | Association between non-alcoholic fatty liver disease and bone turnover biomarkers in post-menopausal women with type 2 diabetes. | 2018 | Details |
| A12727 | 30314924 | Clin Nutr | Critical appraisal for low-carbohydrate diet in nonalcoholic fatty liver disease: Review and meta-analyses. | 2018 | Details |
| A12729 | 30314377 | Pharmaceuticals (Basel) | Obeticholic Acid: A New Era in the Treatment of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12730 | 30314283 | Int J Mol Sci | CEACAM1 in Liver Injury, Metabolic and Immune Regulation. | 2018 | Details |
| A12731 | 30312882 | Ann Diagn Pathol | Nonalcoholic fatty liver disease (NAFLD): Diagnosis, pitfalls, and staging. | 2018 | Details |
| A12732 | 30312631 | Toxicol Appl Pharmacol | Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes. | 2018 | Details |
| A12738 | 30309884 | J Investig Med | Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus. | 2018 | Details |
| A12741 | 30308578 | Eur J Gastroenterol Hepatol | Disease progression of nonalcoholic steatohepatitis in Taiwanese patients: a longitudinal study of paired liver biopsies. | 2019 | Details |
| A12744 | 30306466 | World J Pediatr | Advances in diagnosis of chronic liver diseases in pediatric patients. | 2018 | Details |