Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A23340 | 23860122 | Am J Physiol Endocrinol Metab | MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet. | 2013 | Details |
| A23348 | 23851679 | Food Funct | Oat β-glucan inhibits lipopolysaccharide-induced nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A23365 | 23842720 | Clin Rev Allergy Immunol | Autoimmune features in metabolic liver disease: a single-center experience and review of the literature. | 2013 | Details |
| A23373 | 23835912 | Clin Obstet Gynecol | Developmental programming of pediatric nonalcoholic fatty liver disease: redefining the"first hit". | 2013 | Details |
| A23376 | 23834389 | Hepatol Res | Augmented hepatic Toll-like receptors by fatty acids trigger the pro-inflammatory state of non-alcoholic fatty liver disease in mice. | 2013 | Details |
| A23378 | 23833274 | J Endocrinol | Inflammation as a potential link between nonalcoholic fatty liver disease and insulin resistance. | 2013 | Details |
| A23381 | 23831119 | J Hepatol | Cell-specific PPARγ deficiency establishes anti-inflammatory and anti-fibrogenic properties for this nuclear receptor in non-parenchymal liver cells. | 2013 | Details |
| A23386 | 23827477 | Trends Endocrinol Metab | Non-alcoholic steatohepatitis: a microbiota-driven disease. | 2013 | Details |
| A23400 | 23813132 | Ann Hepatol | Association of plasma visfatin with hepatic and systemic inflammation in nonalcoholic fatty liver disease. | 2013 | Details |
| A23409 | 23805409 | Adipocyte | Sirtuin-1 is a nutrient-dependent modulator of inflammation. | 2013 | Details |
| A23410 | 23805238 | PLoS One | High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats. | 2013 | Details |
| A23414 | 23803760 | Nature | Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. | 2013 | Details |
| A23415 | 23803374 | Hepatogastroenterology | Serum liver fatty acid binding protein shows good correlation with liver histology in NASH. | 2014 | Details |
| A23426 | 23792031 | J Hepatol | The role of hepassocin in the development of non-alcoholic fatty liver disease. | 2013 | Details |
| A23435 | 23786840 | Acta Biochim Biophys Sin (Shanghai) | Neutralization of interleukin-17 attenuates high fat diet-induced non-alcoholic fatty liver disease in mice. | 2013 | Details |
| A23456 | 23762326 | PLoS One | CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model. | 2013 | Details |
| A23463 | 23758436 | Clin Sci (Lond) | Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice. | 2013 | Details |
| A23466 | 23755269 | PLoS One | Lepr(db/db) Mice with senescence marker protein-30 knockout (Lepr(db/db)Smp30(Y/-)) exhibit increases in small dense-LDL and severe fatty liver despite being fed a standard diet. | 2013 | Details |
| A23475 | 23746214 | Clin Endocrinol (Oxf) | A comparison of cardiovascular risk indices in patients with polycystic ovary syndrome with and without coexisting nonalcoholic fatty liver disease. | 2013 | Details |
| A23476 | 23745619 | Metab Syndr Relat Disord | Nonalcoholic fatty liver disease and reduced serum vitamin D(3) levels. | 2013 | Details |
| A23480 | 23743495 | Redox Rep | The relationship between oxidative stress and nonalcoholic fatty liver disease: Its effects on the development of nonalcoholic steatohepatitis. | 2013 | Details |
| A23503 | 26201793 | Hepatol Int | Amelioration of hepatic inflammation in a mouse model of NASH using a dithiocarbamate derivative. | 2013 | Details |
| A23506 | 26201788 | Hepatol Int | Maturation defective myeloid dendritic cells in nonalcoholic fatty liver disease patients release inflammatory cytokines in response to endotoxin. | 2012 | Details |
| A23510 | 25755488 | J Clin Exp Hepatol | Gut-liver axis: role of inflammasomes. | 2013 | Details |
| A23520 | 23714479 | Am Soc Clin Oncol Educ Book | How do mechanisms of hepatocarcinogenesis (HBV, HCV, and NASH) affect our understanding and approach to HCC? | 2013 | Details |
| A23521 | 23714158 | J Hepatol | The metabolomic window into hepatobiliary disease. | 2013 | Details |
| A23528 | 23705529 | Adolesc Med State Art Rev | Update in adolescent gastroenterology. | 2013 | Details |
| A23531 | 23703665 | Hepatology | Advanced glycation endproducts induce fibrogenic activity in nonalcoholic steatohepatitis by modulating TNF-α-converting enzyme activity in mice. | 2013 | Details |
| A23532 | 23703580 | Hepatology | Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2013 | Details |
| A23541 | 23697659 | Antioxid Redox Signal | A novel antihypoglycemic role of inducible nitric oxide synthase in liver inflammatory response induced by dietary cholesterol and endotoxemia. | 2013 | Details |
| A23542 | 23696823 | PLoS One | Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis. | 2013 | Details |
| A23544 | 23695216 | Am J Physiol Endocrinol Metab | Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance. | 2013 | Details |
| A23550 | 23690772 | Int J Endocrinol | Obesity and inflammation: epidemiology, risk factors, and markers of inflammation. | 2013 | Details |
| A23557 | 23682724 | Liver Int | Transgenic expression of human neutrophil peptide-1 enhances hepatic fibrosis in mice fed a choline-deficient, L-amino acid-defined diet. | 2013 | Details |
| A23560 | 23674845 | World J Gastroenterol | Genetic association of interleukin-6 polymorphism (-174 G/C) with chronic liver diseases and hepatocellular carcinoma. | 2013 | Details |
| A23566 | 23669283 | J Hepatol | NKT-cell subsets: promoters and protectors in inflammatory liver disease. | 2013 | Details |
| A23572 | 23665282 | J Hepatol | Food-derived peroxidized fatty acids may trigger hepatic inflammation: a novel hypothesis to explain steatohepatitis. | 2013 | Details |
| A23573 | 23663887 | Zhonghua Gan Zang Bing Za Zhi | [Therapeutic efficacy and mechanisms of quercetin in a rat model of nonalcoholic fatty liver disease]. | 2013 | Details |
| A23574 | 23663767 | Zhonghua Gan Zang Bing Za Zhi | [Effects of quercetin on serum levels of resistin and IL-18 and on insulin resistance in nonalcoholic fatty liver disease rats]. | 2013 | Details |
| A23578 | 23661906 | Mediators Inflamm | Expression of inflammation-related genes is altered in gastric tissue of patients with advanced stages of NAFLD. | 2013 | Details |
| A23596 | 23647015 | Br J Pharmacol | Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. | 2013 | Details |
| A23610 | 23627434 | Clin Sci (Lond) | Fetuin-A mRNA expression is elevated in NASH compared with NAFL patients. | 2013 | Details |
| A23616 | 23625197 | Curr Diab Rep | The future of thiazolidinedione therapy in the management of type 2 diabetes mellitus. | 2013 | Details |
| A23639 | 23605066 | Pflugers Arch | Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation. | 2013 | Details |
| A23642 | 23602473 | Arch Med Res | Relationship between visceral adipose tissue and adiponectin, inflammatory markers and thyroid hormones in obese males with hepatosteatosis and insulin resistance. | 2013 | Details |
| A23649 | 23597944 | Ann Endocrinol (Paris) | Relationship between hepatocellular carcinoma, metabolic syndrome and non-alcoholic fatty liver disease: which clinical arguments? | 2013 | Details |
| A23657 | 23592668 | Obesity (Silver Spring) | Nonalcoholic fatty liver disease in severely obese adolescent and adult patients. | 2013 | Details |
| A23659 | 23592516 | Mol Pharmacol | Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. | 2013 | Details |
| A23665 | 23585904 | PLoS One | Fructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet. | 2013 | Details |
| A23681 | 23567086 | J Hepatol | Decoding cell death signals in liver inflammation. | 2013 | Details |
| A23682 | 23567085 | J Hepatol | Cannabinoid signaling and liver therapeutics. | 2013 | Details |
| A23694 | 23560443 | Int J Exp Pathol | Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice. | 2013 | Details |
| A23696 | 23558065 | Hepatobiliary Pancreat Dis Int | Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges. | 2013 | Details |
| A23699 | 23556042 | World J Hepatol | Silymarin in non alcoholic fatty liver disease. | 2013 | Details |
| A23734 | 23522007 | Psychol Med | Elevated alanine aminotransferase independently predicts new onset of depression in employees undergoing health screening examinations. | 2013 | Details |
| A23743 | 23515587 | Eur J Nutr | Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways. | 2013 | Details |
| A23747 | 23512881 | Obesity (Silver Spring) | A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population. | 2013 | Details |
| A23754 | 23509615 | J Obes | Platelet counts and liver enzymes after bariatric surgery. | 2013 | Details |
| A23760 | 23505183 | Obesity (Silver Spring) | Retinol binding protein-4 circulating levels were higher in nonalcoholic fatty liver disease vs. histologically normal liver from morbidly obese women. | 2013 | Details |
| A23764 | 23504808 | Hepatology | Vitamin D and nonalcoholic fatty liver disease (NAFLD): is it more than just an association? | 2013 | Details |
| A23768 | 23500152 | J Hepatol | Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome. | 2013 | Details |
| A23775 | 23492103 | Gut | Molecular interplay between Δ5/Δ6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis. | 2013 | Details |
| A23783 | 23483818 | World J Gastroenterol | From fatty liver to fibrosis: a tale of "second hit". | 2013 | Details |
| A23786 | 23482247 | World J Gastroenterol | Fructose as a key player in the development of fatty liver disease. | 2013 | Details |
| A23796 | 23476686 | Evid Based Complement Alternat Med | Managing the combination of nonalcoholic Fatty liver disease and metabolic syndrome with chinese herbal extracts in high-fat-diet fed rats. | 2013 | Details |
| A23804 | 23461136 | Adv Clin Chem | Toll-like receptors in liver disease. | 2013 | Details |
| A23805 | 23460643 | J Biol Chem | Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease. | 2013 | Details |
| A23813 | 23452341 | Br J Clin Pharmacol | The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake. | 2014 | Details |
| A23817 | 23451176 | PLoS One | Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis. | 2013 | Details |
| A23825 | 26064833 | J Lifestyle Med | Regulation of Cholesterol Metabolism in Liver: Link to NAFLD and Impact of n-3 PUFAs. | 2013 | Details |
| A23829 | 23442833 | J Clin Gastroenterol | Immune therapy for nonalcoholic steatohepatitis: are we there yet? | 2013 | Details |
| A23840 | 23433458 | Adv Pharmacol | Eicosanoids in metabolic syndrome. | 2013 | Details |
| A23841 | 23432982 | Arab J Gastroenterol | Relationship between non-alcoholic fatty liver disease and kidney function: a communication between two organs that needs further exploration. | 2012 | Details |
| A23842 | 23432843 | Liver Int | GLP-1 analogue prevents NAFLD in ApoE KO mice with diet and Acrp30 knockdown by inhibiting c-JNK. | 2013 | Details |
| A23843 | 23432669 | Curr Pharm Des | Gut-liver axis and microbiota in NAFLD: insight pathophysiology for novel therapeutic target. | 2013 | Details |
| A23853 | 23426790 | Int J Mol Med | Anti-inflammatory effects of total alkaloids from Rubus alceifolius Poir [corrected]. on non-alcoholic fatty liver disease through regulation of the NF-κB pathway. | 2013 | Details |
| A23854 | 23426707 | Exp Clin Endocrinol Diabetes | Liver lipocalin 2 expression in severely obese women with non alcoholic fatty liver disease. | 2013 | Details |
| A23859 | 23424926 | Rev Prat | [Management of non alcoholic fatty liver diseases in adults]. | 2012 | Details |
| A23868 | 23418072 | Obesity (Silver Spring) | A metabolically healthy obese phenotype in hispanic participants in the IRAS family study. | 2013 | Details |
| A23886 | 23402636 | J Med Food | Health benefits of blue-green algae: prevention of cardiovascular disease and nonalcoholic fatty liver disease. | 2013 | Details |
| A23896 | 23397556 | Semin Thromb Hemost | Diagnosis and management of nonalcoholic fatty liver disease and its hemostatic/thrombotic and vascular complications. | 2013 | Details |
| A23901 | 23395669 | Toxicol In Vitro | Sophocarpine alleviates hepatocyte steatosis through activating AMPK signaling pathway. | 2013 | Details |
| A23908 | 23394092 | Curr Pharm Des | Pathophysiology of NASH: perspectives for a targeted treatment. | 2013 | Details |
| A23911 | 23392905 | Clin Chem Lab Med | Serum carcinoembryonic antigen is associated with non-alcoholic fatty liver disease in healthy Korean non-smokers. | 2013 | Details |
| A23924 | 23385644 | J Mol Med (Berl) | Lack of kinin B₁ receptor potentiates leptin action in the liver. | 2013 | Details |
| A23939 | 23370355 | Biol Pharm Bull | A novel inhibitor of stearoyl-CoA desaturase-1 attenuates hepatic lipid accumulation, liver injury and inflammation in model of nonalcoholic steatohepatitis. | 2013 | Details |
| A23950 | 23356584 | Liver Int | Heterogeneity of fibrosis patterns in non-alcoholic fatty liver disease supports the presence of multiple fibrogenic pathways. | 2013 | Details |
| A23952 | 23355910 | World J Hepatol | Is nonalcoholic fatty liver disease the hepatic expression of the metabolic syndrome? | 2012 | Details |
| A23962 | 23348005 | Toxicol In Vitro | Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells. | 2013 | Details |
| A23963 | 23347840 | Clin Res Hepatol Gastroenterol | Non-alcoholic steatohepatitis in morbidly obese patients. | 2013 | Details |
| A23967 | 23346097 | Front Genet | Molecular Interactions between NAFLD and Xenobiotic Metabolism. | 2013 | Details |
| A23972 | 23334462 | Diabetologia | Adipose tissue is inflamed in NAFLD due to obesity but not in NAFLD due to genetic variation in PNPLA3. | 2013 | Details |
| A23976 | 23331460 | Basic Clin Pharmacol Toxicol | Quercetin decreases liver damage in mice with non-alcoholic steatohepatitis. | 2013 | Details |
| A23997 | 23317398 | Curr Pharm Des | Ezetimibe therapy for dyslipidemia: an update. | 2013 | Details |
| A23998 | 23316084 | J Clin Endocrinol Metab | Insulin-like growth factor-I, inflammatory proteins, and fibrosis in subjects with nonalcoholic fatty liver disease. | 2013 | Details |
| A24004 | 23307045 | J Gastroenterol | Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice. | 2013 | Details |
| A24008 | 23304532 | Int J Hepatol | Multidisciplinary pharmacotherapeutic options for nonalcoholic Fatty liver disease. | 2012 | Details |
| A24009 | 23304464 | J Obes | The relationship between nonalcoholic fatty liver disease and colorectal cancer: the future challenges and outcomes of the metabolic syndrome. | 2012 | Details |
| A24019 | 23299577 | Hepatology | Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models. | 2013 | Details |
| A24025 | 23295058 | Liver Int | Rosuvastatin ameliorates high-fat and high-cholesterol diet-induced nonalcoholic steatohepatitis in rats. | 2013 | Details |