Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A12754 | 30300671 | Biochim Biophys Acta Mol Basis Dis | Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice. | 2018 | Details |
| A12756 | 30300287 | Transplantation | Nonalcoholic Fatty Liver Disease: Basic Pathogenetic Mechanisms in the Progression From NAFLD to NASH. | 2019 | Details |
| A12758 | 30299993 | Expert Opin Pharmacother | Pharmacotherapy of type 2 diabetes in patients with chronic liver disease: focus on nonalcoholic fatty liver disease. | 2018 | Details |
| A12763 | 30298568 | Liver Int | Predictors of nonalcoholic steatohepatitis and significant fibrosis in non-obese nonalcoholic fatty liver disease. | 2018 | Details |
| A12768 | 30297615 | Nutrients | Gut Microbiota's Relationship with Liver Disease and Role in Hepatoprotection by Dietary Natural Products and Probiotics. | 2018 | Details |
| A12769 | 30295948 | Aliment Pharmacol Ther | Liver fat scores predict liver disease mortality in the United States population. | 2018 | Details |
| A12770 | 30295789 | Endocrinology | Adult-Onset Hepatocyte GH Resistance Promotes NASH in Male Mice, Without Severe Systemic Metabolic Dysfunction. | 2018 | Details |
| A12774 | 30293065 | Ann Nutr Metab | Cholesteryl Ester Transfer Protein Variant (RS1800777) with Liver Histology in Non-Alcoholic Fatty Liver Disease Patients. | 2018 | Details |
| A12780 | 30291868 | J Hepatol | Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib. | 2018 | Details |
| A12782 | 30290973 | J Hepatol | An internet-based approach for lifestyle changes in patients with NAFLD: Two-year effects on weight loss and surrogate markers. | 2018 | Details |
| A12783 | 30288767 | Aliment Pharmacol Ther | Predictors of advanced fibrosis in non-cirrhotic non-alcoholic fatty liver disease in Germany. | 2018 | Details |
| A12786 | 30288476 | Hepatol Commun | Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12787 | 30288073 | Diabetes Metab Syndr Obes | Obesity and nonalcoholic fatty liver disease: current perspectives. | 2018 | Details |
| A12798 | 30283798 | World J Clin Cases | PNPLA3 rs139051 is associated with phospholipid metabolite profile and hepatic inflammation in nonalcoholic fatty liver disease. | 2018 | Details |
| A12800 | 30283077 | Int J Obes (Lond) | Ascorbic acid inhibits visceral obesity and nonalcoholic fatty liver disease by activating peroxisome proliferator-activated receptor α in high-fat-diet-fed C57BL/6J mice. | 2018 | Details |
| A12807 | 30274911 | Clin Res Hepatol Gastroenterol | Association of glycated hemoglobin with the risk of advanced fibrosis in non-alcoholic fatty liver disease patients without diabetes. | 2018 | Details |
| A12808 | 30274326 | Diseases | When to Initiate Weight Loss Medications in the NAFLD Population. | 2018 | Details |
| A12810 | 30273934 | Horm Metab Res | Noninvasive Liver Fibrosis Tests in Patients with Nonalcoholic Fatty Liver Disease: An External Validation Cohort. | 2018 | Details |
| A12814 | 30272604 | Gastroenterol Nurs | The Role of the Nurse Practitioner in the Management of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12815 | 30271746 | J Clin Transl Hepatol | The Genetics of Clinical Liver Diseases: Insight into the TM6SF2 E167K Variant. | 2018 | Details |
| A12817 | 30270688 | Scand J Gastroenterol | Treatment of non-alcoholic steatohepatitis patients with vitamin D: a double-blinded, randomized, placebo-controlled pilot study. | 2018 | Details |
| A12818 | 30270343 | Med Sci Monit | Altered DNA Methylation Sites in Peripheral Blood Leukocytes from Patients with Simple Steatosis and Nonalcoholic Steatohepatitis (NASH). | 2018 | Details |
| A12820 | 30269271 | Dig Dis Sci | Ultrasonographic Nonalcoholic Fatty Pancreas Is Associated with Advanced Fibrosis in NAFLD: A Retrospective Analysis. | 2018 | Details |
| A12822 | 30266645 | Int J Biol Macromol | Lycium barbarum polysaccharides improve hepatic injury through NFkappa-B and NLRP3/6 pathways in a methionine choline deficient diet steatohepatitis mouse model. | 2018 | Details |
| A12826 | 30266159 | Clin Liver Dis | Nonalcoholic Liver Disease in Children and Adolescents. | 2018 | Details |
| A12827 | 30266038 | Br J Pharmacol | Diethyldithiocarbamate, an anti-abuse drug, alleviates steatohepatitis and fibrosis in rodents through modulating lipid metabolism and oxidative stress. | 2018 | Details |
| A12828 | 30265706 | PLoS One | Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study. | 2018 | Details |
| A12830 | 30264828 | AIDS Rev | Non-Alcoholic Fatty Liver Disease in Patients with HIV Infection | 2018 | Details |
| A12832 | 30262993 | Int J Biol Sci | Polydatin attenuates diet-induced nonalcoholic steatohepatitis and fibrosis in mice. | 2018 | Details |
| A12835 | 30261763 | Expert Rev Gastroenterol Hepatol | An update on the recent advances in antifibrotic therapy. | 2018 | Details |
| A12837 | 30261472 | Atherosclerosis | Circulating PCSK9 levels are not associated with the severity of hepatic steatosis and NASH in a high-risk population. | 2018 | Details |
| A12841 | 30259536 | Hepatology | Angiopoietin-2 Promotes Pathological Angiogenesis and Is a Therapeutic Target in Murine Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12858 | 30253056 | Liver Int | Cardiovascular risk factors in non-alcoholic fatty liver disease. | 2018 | Details |
| A12859 | 30253043 | Liver Int | Relationship between three commonly used non-invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non-alcoholic steatohepatitis. | 2019 | Details |
| A12860 | 30252499 | Biomarkers | Circulating liver-specific microRNAs as noninvasive diagnostic biomarkers of hepatic diseases in human. | 2018 | Details |
| A12864 | 30250076 | Nat Rev Gastroenterol Hepatol | Apoptosis and necroptosis in the liver: a matter of life and death. | 2018 | Details |
| A12865 | 30249980 | Diseases | Judicious Use of Lipid Lowering Agents in the Management of NAFLD. | 2018 | Details |
| A12866 | 30249972 | Diseases | The Role of Vitamin E in the Treatment of NAFLD. | 2018 | Details |
| A12872 | 30248234 | Liver Int | Hepatic fat as clinical outcome and therapeutic target for nonalcoholic fatty liver disease. | 2018 | Details |
| A12874 | 30248223 | Obes Rev | Adipose may actively delay progression of NAFLD by releasing tumor-suppressing, anti-fibrotic miR-122 into circulation. | 2018 | Details |
| A12878 | 30244972 | Cell Metab | Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma. | 2018 | Details |
| A12889 | 30240470 | J Gastrointestin Liver Dis | Genetic Variants in nicotinamide-N-methyltransferase (NNMT) gene are related to the stage of non-alcoholic fatty liver disease diagnosed by controlled attenuation parameter (CAP)-fibroscan. | 2018 | Details |
| A12891 | 30239004 | J Cell Physiol | Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis. | 2018 | Details |
| A12895 | 30236852 | Biomed Pharmacother | Protective effects of Kangxian ruangan capsule against nonalcoholic fatty liver disease fibrosis in rats induced by MCD diet. | 2018 | Details |
| A12900 | 30235442 | Cell Physiol Biochem | Genipin Reverses HFD-Induced Liver Damage and Inhibits UCP2-Mediated Pyroptosis in Mice. | 2018 | Details |
| A12901 | 30234644 | Eur J Gastroenterol Hepatol | Marijuana is not associated with progression of hepatic fibrosis in liver disease: a systematic review and meta-analysis. | 2019 | Details |
| A12905 | 30231595 | Nutrients | Soybean Oil-Derived Poly-Unsaturated Fatty Acids Enhance Liver Damage in NAFLD Induced by Dietary Cholesterol. | 2018 | Details |
| A12908 | 30231008 | Clin Chem Lab Med | Serum cytokines, adipokines and ferritin for non-invasive assessment of liver fibrosis in chronic liver disease: a systematic review. | 2019 | Details |
| A12913 | 30229460 | Obes Surg | Effect of Body Mass Index, Metabolic Health and Adipose Tissue Inflammation on the Severity of Non-alcoholic Fatty Liver Disease in Bariatric Surgical Patients: a Prospective Study. | 2019 | Details |
| A12914 | 30228976 | Can J Gastroenterol Hepatol | Molecular Pathogenesis of Nonalcoholic Steatohepatitis- (NASH-) Related Hepatocellular Carcinoma. | 2018 | Details |
| A12921 | 30226889 | PLoS One | Prevalence of hepatic steatosis as assessed by controlled attenuation parameter (CAP) in subjects with metabolic risk factors in primary care. A population-based study. | 2018 | Details |
| A12927 | 30222962 | Gastroenterology | Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12932 | 30220454 | Cell | ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. | 2018 | Details |
| A12933 | 30219279 | J Control Release | Therapeutic inhibition of spleen tyrosine kinase in inflammatory macrophages using PLGA nanoparticles for the treatment of non-alcoholic steatohepatitis. | 2018 | Details |
| A12936 | 30218679 | J Hepatol | MicroRNA-378 promotes hepatic inflammation and fibrosis via modulation of the NF-κB-TNFα pathway. | 2018 | Details |
| A12947 | 30213555 | Gastroenterology | Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice. | 2018 | Details |
| A12950 | 30212992 | Medicine (Baltimore) | Risk factors associated with nonalcohol fatty liver disease and fibrosis among patients with type 2 diabetes mellitus. | 2018 | Details |
| A12953 | 30211140 | Can J Gastroenterol Hepatol | Ultrasound Grade of Liver Steatosis Is Independently Associated with the Risk of Metabolic Syndrome. | 2018 | Details |
| A12959 | 30208322 | Cell Rep | FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury. | 2018 | Details |
| A12965 | 30206277 | Sci Rep | Identification of differentially methylated region (DMR) networks associated with progression of nonalcoholic fatty liver disease. | 2018 | Details |
| A12967 | 30205811 | BMC Med | An exploratory study examining how nano-liquid chromatography-mass spectrometry and phosphoproteomics can differentiate patients with advanced fibrosis and higher percentage collagen in non-alcoholic fatty liver disease. | 2018 | Details |
| A12970 | 30202817 | Hepatol Commun | Whole-Exome Sequencing Study of Extreme Phenotypes of NAFLD. | 2018 | Details |
| A12971 | 30202815 | Hepatol Commun | Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity. | 2018 | Details |
| A12972 | 30201879 | Diseases | Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD. | 2018 | Details |
| A12980 | 30197624 | Front Endocrinol (Lausanne) | Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches. | 2018 | Details |
| A12981 | 30197529 | Clin Exp Gastroenterol | Liver function tests in identifying patients with liver disease. | 2018 | Details |
| A12987 | 30194936 | Eur J Pharmacol | Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. | 2018 | Details |
| A12990 | 30193922 | J Hepatol | Dietary exacerbation of metabolic stress leads to accelerated hepatic carcinogenesis in glycogen storage disease type Ia. | 2018 | Details |
| A12992 | 30192782 | PLoS One | Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 randomized clinical trial. | 2018 | Details |
| A12993 | 30191499 | Dig Dis Sci | Silybin Alleviates Hepatic Steatosis and Fibrosis in NASH Mice by Inhibiting Oxidative Stress and Involvement with the Nf-κB Pathway. | 2018 | Details |
| A12995 | 30190781 | World J Hepatol | Current status of imaging in nonalcoholic fatty liver disease. | 2018 | Details |
| A13003 | 30186230 | Front Endocrinol (Lausanne) | Succinate as a Regulator of Hepatic Stellate Cells in Liver Fibrosis. | 2018 | Details |
| A13007 | 30183584 | Chirurgia (Bucur) | The Role of Beta-7 Integrin and Carbonic Anhydrase IX in Predicting the Occurrence of de Novo Nonalcoholic Fatty Liver Disease in Liver Transplant Recipients. | 2019 | Details |
| A13009 | 30183139 | Mol Nutr Food Res | Gamma-Tocotrienol Attenuates the Hepatic Inflammation and Fibrosis by Suppressing Endoplasmic Reticulum Stress in Mice. | 2018 | Details |
| A13011 | 30182166 | Hepatol Int | Serum ferritin level is associated with liver steatosis and fibrosis in Korean general population. | 2018 | Details |
| A13013 | 30180767 | Am J Chin Med | Gypenoside UL4-Rich Gynostemma pentaphyllum Extract Exerts a Hepatoprotective Effect on Diet-Induced Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13014 | 30180301 | Basic Clin Pharmacol Toxicol | Protective effect of isochlorogenic acid B on liver fibrosis in non-alcoholic steatohepatitis of mice. | 2018 | Details |
| A13015 | 30180285 | Hepatology | Burden of Illness and Economic Model for Patients With Nonalcoholic Steatohepatitis in the United States. | 2019 | Details |
| A13019 | 30179227 | Eur J Gastroenterol Hepatol | Evaluation of liver steatosis, measured by controlled attenuation parameter, in patients with hepatitis C-induced advanced liver fibrosis and hepatocellular carcinoma. | 2018 | Details |
| A13020 | 30178600 | Diabetes Obes Metab | Evaluation of the effects of dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on hepatic steatosis and fibrosis using transient elastography in patients with type 2 diabetes and non-alcoholic fatty liver disease. | 2018 | Details |
| A13023 | 30176114 | Liver Int | Relationship between non-alcoholic steatohepatitis, PNPLA3 I148M genotype and bone mineral density in adolescents. | 2018 | Details |
| A13028 | 30174213 | Lancet Diabetes Endocrinol | Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies. | 2018 | Details |
| A13033 | 30171810 | Horm Mol Biol Clin Investig | Metalloproteinases in non-alcoholic fatty liver disease and their behavior in liver fibrosis. | 2018 | Details |
| A13035 | 30171159 | Mol Cell Proteomics | Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits. | 2018 | Details |
| A13036 | 30171065 | Gut | Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease. | 2018 | Details |
| A13045 | 30166857 | World J Gastroenterol | Helicobacter pylori infection and liver diseases: Epidemiology and insights into pathogenesis. | 2018 | Details |
| A13046 | 30166633 | Am J Gastroenterol | Alcohol Consumption in Patients with Non-alcoholic Fatty Liver Disease: Convenient vs. Inconvenient Truths. | 2018 | Details |
| A13050 | 30161179 | PLoS One | Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis. | 2018 | Details |
| A13052 | 30160786 | J Gastroenterol Hepatol | Caspase-independent hepatocyte death: A result of the decrease of lysophosphatidylcholine acyltransferase 3 in non-alcoholic steatohepatitis. | 2018 | Details |
| A13081 | 30145565 | Ann Hepatol | Thyroid Function and Risk of Non-Alcoholic Fatty Liver Disease in Euthyroid Subjects. | 2018 | Details |
| A13082 | 30144554 | J Hepatol | The conundrum of cryptogenic cirrhosis: Adverse outcomes without treatment options. | 2018 | Details |
| A13084 | 30144360 | J Gastroenterol Hepatol | Utility and limitations of noninvasive fibrosis markers for predicting prognosis in biopsy-proven Japanese non-alcoholic fatty liver disease patients. | 2018 | Details |
| A13089 | 30142943 | Nutrients | Nutraceutical Approach to Non-Alcoholic Fatty Liver Disease (NAFLD): The Available Clinical Evidence. | 2018 | Details |
| A13091 | 30142428 | J Hepatol | miRNAs in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2018 | Details |
| A13097 | 30139901 | BMJ Open | Diagnostic accuracy of point shear wave elastography and transient elastography for staging hepatic fibrosis in patients with non-alcoholic fatty liver disease: a meta-analysis. | 2018 | Details |
| A13099 | 30139362 | BMC Med | Putting non-alcoholic fatty liver disease on the radar for primary care physicians: how well are we doing? | 2018 | Details |
| A13106 | 30135638 | Cent Eur J Immunol | Changes in the immune system - the key to diagnostics and therapy of patients with non-alcoholic fatty liver disease. | 2018 | Details |
| A13114 | 30134610 | Noncoding RNA | The Role of Long Non-Coding RNAs (lncRNAs) in the Development and Progression of Fibrosis Associated with Nonalcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13115 | 30134384 | Eur J Gastroenterol Hepatol | Serum biomarkers of fibrosis and extracellular matrix remodeling in patients with nonalcoholic fatty liver disease: association with liver histology. | 2019 | Details |
| A13132 | 30122876 | World J Gastroenterol | Current guidelines for the management of non-alcoholic fatty liver disease: A systematic review with comparative analysis. | 2018 | Details |