Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24783 | 22504749 | Br J Hosp Med (Lond) | Hepatic encephalopathy. | 2012 | Details |
| A24796 | 22481692 | Arq Gastroenterol | Metabolic syndrome and risk factors for non-alcoholic fatty liver disease. | 2012 | Details |
| A24805 | 22470565 | PLoS One | Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells. | 2012 | Details |
| A24808 | 22469640 | J Clin Gastroenterol | The role of nutrients in the development, progression, and treatment of nonalcoholic fatty liver disease. | 2012 | Details |
| A24812 | 22364603 | Actas Dermosifiliogr | [Integrated approach to comorbidity in patients with psoriasis.Working Group on Psoriasis-associated Comorbidities]. | 2012 | Details |
| A24814 | 22468051 | Indian J Clin Biochem | Role of cytokines in the pathogenesis of non-alcoholic Fatty liver disease. | 2011 | Details |
| A24825 | 22462240 | J Tradit Chin Med | Dangfei liganning capsules attenuate the susceptibility of rat nonalcoholic fatty liver to carbon tetrachloride toxicity. | 2011 | Details |
| A24830 | 22455888 | Zhonghua Bing Li Xue Za Zhi | [Mechanism of hepatocyte apoptosis in rats with liver fibrosis induced by lipogenic methionine-choline-deficient diet]. | 2012 | Details |
| A24831 | 22451385 | Biosci Biotechnol Biochem | Effects of lotus root (the edible rhizome of Nelumbo nucifera) on the deveolopment of non-alcoholic fatty liver disease in obese diabetic db/db mice. | 2012 | Details |
| A24846 | 22434757 | Pediatr Obes | Serum protein N-glycosylation in paediatric non-alcoholic fatty liver disease. | 2012 | Details |
| A24851 | 22432836 | J Gastroenterol Hepatol | Assessment of inflammation and fibrosis in non-alcoholic fatty liver disease by imaging-based techniques. | 2012 | Details |
| A24852 | 22432744 | J Gastroenterol Hepatol | Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. | 2012 | Details |
| A24861 | 22425624 | J Hepatol | Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis. | 2012 | Details |
| A24864 | 22420611 | Clin Sci (Lond) | Beneficial effects of rosuvastatin on insulin resistance, adiposity, inflammatory markers and non-alcoholic fatty liver disease in mice fed on a high-fat diet. | 2012 | Details |
| A24870 | 22418887 | Semin Liver Dis | Hypercoagulation and thrombophilia in nonalcoholic fatty liver disease: mechanisms, human evidence, therapeutic implications, and preventive implications. | 2012 | Details |
| A24873 | 22418884 | Semin Liver Dis | NAFLD in the absence of metabolic syndrome: different epidemiology, pathogenetic mechanisms, risk factors for disease progression? | 2012 | Details |
| A24876 | 22414386 | Toxicol Lett | Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model. | 2012 | Details |
| A24879 | 22408036 | Eur Heart J | Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor? | 2012 | Details |
| A24900 | 22380754 | BMC Gastroenterol | Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24905 | 22374723 | Histol Histopathol | Histological and immunohistochemical assessment of liver biopsies in morbidly obese patients. | 2012 | Details |
| A24911 | 22371632 | World J Gastroenterol | Role of cytokines and chemokines in non-alcoholic fatty liver disease. | 2012 | Details |
| A24924 | 22351677 | In Vivo | Detecting plasma cell precursors in autoimmune hepatitis. | 2012 | Details |
| A24940 | 22334337 | Hepatology | Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice. | 2012 | Details |
| A24951 | 22326434 | Gastroenterology | Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. | 2012 | Details |
| A24954 | 22315014 | Endocrine | The role of pro/anti-inflammatory adipokines on bone metabolism in NAFLD obese adolescents: effects of long-term interdisciplinary therapy. | 2012 | Details |
| A24957 | 22313887 | Zhong Xi Yi Jie He Xue Bao | [Effects of the mixture of Swertia pseudochinensis Hara and Silybum marianum Gaertn extracts on CCl(4)-induced liver injury in rats with non-alcoholic fatty liver disease]. | 2012 | Details |
| A24959 | 22311412 | Chin J Integr Med | Chinese herbal medicine in the treatment of nonalcoholic fatty liver disease. | 2012 | Details |
| A24960 | 22310735 | J Gastroenterol | Inflammation and fibrogenesis in steatohepatitis. | 2012 | Details |
| A24968 | 22297845 | Nature | Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. | 2012 | Details |
| A24970 | 22295101 | PLoS One | LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. | 2012 | Details |
| A24972 | 22294100 | Cell Mol Life Sci | A role for sphingolipids in the pathophysiology of obesity-induced inflammation. | 2012 | Details |
| A24975 | 22290395 | Hepatology | Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis. | 2012 | Details |
| A24976 | 22288305 | Eur Rev Med Pharmacol Sci | The psoriatic patient profile for infliximab. | 2011 | Details |
| A24984 | 22278337 | Diabetologia | Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials. | 2012 | Details |
| A24986 | 22278044 | Eur J Nutr | Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model. | 2012 | Details |
| A24987 | 22275361 | J Biol Chem | Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. | 2012 | Details |
| A24992 | 22271167 | Hepatology | Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice. | 2012 | Details |
| A24994 | 22269154 | Gene | Association of adiponectin gene functional polymorphisms (-11377C/G and +45T/G) with nonalcoholic fatty liver disease. | 2011 | Details |
| A24997 | 22265683 | Dig Liver Dis | Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property. | 2012 | Details |
| A25001 | 22257474 | J Dig Dis | Liver X receptors bridge hepatic lipid metabolism and inflammation. | 2012 | Details |
| A25004 | 22253482 | Gut | Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice. | 2012 | Details |
| A25026 | 22236001 | Clin Exp Immunol | Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells. | 2012 | Details |
| A25031 | 22228717 | Diabetes | TIMP3 overexpression in macrophages protects from insulin resistance, adipose inflammation, and nonalcoholic fatty liver disease in mice. | 2012 | Details |
| A25032 | 22228550 | J Clin Immunol | The role of innate cells is coupled to a Th1-polarized immune response in pediatric nonalcoholic steatohepatitis. | 2012 | Details |
| A25044 | 22221215 | Nutr Rev | Therapeutic potential of green tea in nonalcoholic fatty liver disease. | 2012 | Details |
| A25070 | 22197629 | Dig Liver Dis | Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. | 2011 | Details |
| A25083 | 22183915 | Hepatology | Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease. | 2012 | Details |
| A25093 | 22179204 | Mol Med Rep | Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism. | 2011 | Details |
| A25094 | 22176347 | Hepatol Res | High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism. | 2011 | Details |
| A25113 | 22160635 | Dig Dis Sci | Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD. | 2011 | Details |
| A25115 | 22157544 | J Nutr | Green tea extract suppresses NFκB activation and inflammatory responses in diet-induced obese rats with nonalcoholic steatohepatitis. | 2011 | Details |
| A25120 | 22155236 | Biochem Biophys Res Commun | Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model. | 2011 | Details |
| A25126 | 22152380 | Zhonghua Gan Zang Bing Za Zhi | [SREBP-1c knockdown attenuated fatty degeneration in hepatic L02 cells and inhibited CCL2 and FGF21 protein expression]. | 2011 | Details |
| A25127 | 22152379 | Zhonghua Gan Zang Bing Za Zhi | [Establishment and identification of non-alcoholic fatty liver disease in chronic hepatitis B virus infected mice]. | 2011 | Details |
| A25128 | 22152378 | Zhonghua Gan Zang Bing Za Zhi | [The role of Fas mutation on non-alcoholic steatohepatitis in mice]. | 2011 | Details |
| A25133 | 22152320 | Zhonghua Gan Zang Bing Za Zhi | [Effects of telmisartan on nonalcoholic steatohepatitis rat model by activating peroxisome proliferator-activated receptor r]. | 2011 | Details |
| A25139 | 22149546 | Diabetes Technol Ther | Inflammatory markers in relation to nonalcoholic fatty liver disease in urban South Indians. | 2011 | Details |
| A25142 | 22142284 | Clin Sci (Lond) | Bias in macrophage activation pattern influences non-alcoholic steatohepatitis (NASH) in mice. | 2012 | Details |
| A25155 | 22129639 | J Nutr Biochem | The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease. | 2011 | Details |
| A25156 | 22126450 | Scand J Gastroenterol | Low clinical relevance of the nonalcoholic fatty liver disease activity score (NAS) in predicting fibrosis progression. | 2011 | Details |
| A25161 | 22122481 | Curr Pharm Biotechnol | Non-alcoholic steatohepatitis: new insights from OMICS studies. | 2012 | Details |
| A25162 | 22121808 | Zhongguo Zhong Yao Za Zhi | [Effect of total alkaloids of Rubus alceaefolius on oxidative stress in rats with non-alcoholic fatty liver disease]. | 2011 | Details |
| A25174 | 22112193 | Metab Syndr Relat Disord | Association of serum lipoprotein-associated phospholipase A2 level with nonalcoholic fatty liver disease. | 2011 | Details |
| A25176 | 22111040 | Diabetes Metab J | Dietary oleate has beneficial effects on every step of non-alcoholic Fatty liver disease progression in a methionine- and choline-deficient diet-fed animal model. | 2011 | Details |
| A25178 | 22110478 | Exp Diabetes Res | Role of transcription factor modifications in the pathogenesis of insulin resistance. | 2011 | Details |
| A25184 | 22108588 | Exp Cell Res | A methionine-choline-deficient diet elicits NASH in the immunodeficient mouse featuring a model for hepatic cell transplantation. | 2011 | Details |
| A25191 | 22103753 | Pharm Biol | Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: impact of nonalcoholic fatty liver disease. | 2011 | Details |
| A25198 | 22098270 | Liver Int | Impaired renal function in morbid obese patients with nonalcoholic fatty liver disease. | 2011 | Details |
| A25199 | 22098164 | J Gastroenterol Hepatol | Inflammatory stress exacerbates hepatic cholesterol accumulation via disrupting cellular cholesterol export. | 2012 | Details |
| A25200 | 22097893 | Liver Int | Neutrophil to lymphocyte ratio: a new marker for predicting steatohepatitis and fibrosis in patients with nonalcoholic fatty liver disease. | 2011 | Details |
| A25206 | 22094893 | Curr Top Microbiol Immunol | Contribution of the intestinal microbiota to human health: from birth to 100 years of age. | 2013 | Details |
| A25213 | 22087354 | World J Diabetes | A defect in the activities of Δ and Δ desaturases and pro-resolution bioactive lipids in the pathobiology of non-alcoholic fatty liver disease. | 2011 | Details |
| A25224 | 22081919 | HPB (Oxford) | Metabolic syndrome and hepatic resection: improving outcome. | 2011 | Details |
| A25232 | 22072427 | Metab Brain Dis | Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy. | 2011 | Details |
| A25236 | 22064361 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. | 2011 | Details |
| A25237 | 22064320 | Lab Invest | A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein. | 2011 | Details |
| A25240 | 22059109 | World J Hepatol | Role of ezetimibe in non-alcoholic fatty liver disease. | 2011 | Details |
| A25261 | 22027586 | J Hepatol | Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans. | 2011 | Details |
| A25276 | 22015687 | Clin Biochem | Some inflammatory cytokine levels, iron metabolism and oxidan stress markers in subjects with nonalcoholic steatohepatitis. | 2011 | Details |
| A25283 | 22008843 | Food Funct | The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity. | 2011 | Details |
| A25284 | 22002020 | Curr Opin Lipidol | Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic. | 2011 | Details |
| A25287 | 21994008 | Hepatology | Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation. | 2012 | Details |
| A25288 | 21991518 | ISRN Gastroenterol | Obesity, Visceral Fat, and NAFLD: Querying the Role of Adipokines in the Progression of Nonalcoholic Fatty Liver Disease. | 2011 | Details |
| A25294 | 21987620 | World J Gastroenterol | JNKs, insulin resistance and inflammation: A possible link between NAFLD and coronary artery disease. | 2011 | Details |
| A25298 | 21986673 | Eur J Nutr | Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFα. | 2011 | Details |
| A25302 | 21985374 | Clin Exp Immunol | Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease. | 2011 | Details |
| A25316 | 21963507 | Biol Pharm Bull | meso-Dihydroguaiaretic acid inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells. | 2011 | Details |
| A25330 | 21952989 | Hepatology | "Normal" liver stiffness measure (LSM) values are higher in both lean and obese individuals: a population-based study from a developing country. | 2011 | Details |
| A25338 | 21948338 | Dig Dis Sci | Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease. | 2011 | Details |
| A25341 | 21947639 | Nutr Clin Pract | Nonalcoholic fatty liver disease: a review of the spectrum of disease, diagnosis, and therapy. | 2011 | Details |
| A25345 | 21943357 | Nutr Metab (Lond) | The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic fatty liver disease (NAFLD) in rats. | 2011 | Details |
| A25359 | 21930273 | Atherosclerosis | NASH and atherosclerosis are two aspects of a shared disease: central role for macrophages. | 2011 | Details |
| A25360 | 21929649 | J Gastroenterol Hepatol | Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis. | 2012 | Details |
| A25363 | 21918648 | Curr Gerontol Geriatr Res | Mechanisms and implications of age-related changes in the liver: nonalcoholic Fatty liver disease in the elderly. | 2011 | Details |
| A25376 | 21910083 | Adv Exp Med Biol | Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity. | 2011 | Details |
| A25378 | 21907687 | J Hepatol | Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis. | 2011 | Details |
| A25380 | 21906580 | Am J Pathol | Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25403 | 21886908 | Sci Pharm | Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines. | 2011 | Details |
| A25405 | 21885686 | Am J Physiol Gastrointest Liver Physiol | Estrogen deficiency worsens steatohepatitis in mice fed high-fat and high-cholesterol diet. | 2011 | Details |
| A25410 | 21881966 | Metab Brain Dis | Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction. | 2011 | Details |