Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Polyunsaturated Fatty Acids353 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A47290 | 19003881 | Hepatology | Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms. | 2008 | Details |
| A47343 | 15519643 | J Hepatol | Polyunsaturated fatty acid deficiency reverses effects of alcohol on mitochondrial energy metabolism. | 2004 | Details |
| A47391 | 9544451 | Clin Chim Acta | Erythrocyte membrane lipids and serum selenium in post-viral and alcoholic cirrhosis. | 1998 | Details |
| A47393 | 9514306 | Alcohol Clin Exp Res | Increased circulating products of lipid peroxidation in patients with alcoholic liver disease. | 1998 | Details |
| A47405 | 9113278 | Alcohol Clin Exp Res | Polyenylphosphatidylcholine decreases alcohol-induced oxidative stress in the baboon. | 1997 | Details |
| A47406 | 9364195 | Life Sci | Polyenylphosphatidylcholine decreases alcoholic hyperlipemia without affecting the alcohol-induced rise of HDL-cholesterol. | 1997 | Details |
| A47412 | 8667240 | J Pharmacol Exp Ther | Medium chain triglycerides and vitamin E reduce the severity of established experimental alcoholic liver disease. | 1996 | Details |
| A47511 | 3325893 | Pathol Biol (Paris) | [Hemorheological disorders linked to alcoholism]. | 1987 | Details |
| A47531 | 2873160 | J Am Coll Nutr | Control of polyunsaturated acids in tissue lipids. | 1986 | Details |
| A48141 | 21697078 | Am J Clin Nutr | Disrupted fat distribution and composition due to medium-chain triglycerides in mice with a β-oxidation defect. | 2011 | Details |
| A48423 | 11557505 | Am J Physiol Gastrointest Liver Physiol | Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription. | 2001 | Details |
| A48858 | 26443688 | Liver Int | Dietary fatty acids and risk of hepatocellular carcinoma in the Singapore Chinese health study. | 2015 | Details |
| A48908 | 24814604 | Am J Pathol | Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betaine in rat. | 2014 | Details |
| A49367 | 35775425 | Clin Sci (Lond) | Early biochemical observations point to nutritional strategies to manage non-alcoholic fatty liver disease. | 2022 | Details |
| A49463 | 35744053 | Medicina (Kaunas) | Deuterium-Reinforced Polyunsaturated Fatty Acids Prevent Diet-Induced Nonalcoholic Steatohepatitis by Reducing Oxidative Stress. | 2022 | Details |
| A49630 | 35685535 | Int J Clin Pract | Sesame Oil Ameliorates Alanine Aminotransferase, Aspartate Aminotransferase, and Fatty Liver Grade in Women with Nonalcoholic Fatty Liver Disease Undergoing Low-Calorie Diet: A Randomized Double-Blind Controlled Trial. | 2022 | Details |
| A49643 | 35682720 | Int J Mol Sci | Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD. | 2022 | Details |
| A49750 | 35648467 | Am J Clin Nutr | Associations of serum n-3 and n-6 polyunsaturated fatty acids with prevalence and incidence of non-alcoholic fatty liver disease. | 2022 | Details |
| A49805 | 35631319 | Nutrients | Reduction of De Novo Lipogenesis Mediates Beneficial Effects of Isoenergetic Diets on Fatty Liver: Mechanistic Insights from the MEDEA Randomized Clinical Trial. | 2022 | Details |
| A50066 | 35537354 | Prostaglandins Leukot Essent Fatty Acids | Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver disease. | 2022 | Details |
| A50303 | 35438091 | Food Funct | Changes in the serum metabolomic profiles of subjects with NAFLD in response to n-3 PUFAs and phytosterol ester: a double-blind randomized controlled trial. | 2022 | Details |
| A50761 | 35276784 | Nutrients | Effects of Fish Oil Supplementation on Oxidative Stress Biomarkers and Liver Damage in Hypercholesterolemic Rats. | 2022 | Details |
| A50794 | 35263694 | Clin Nutr | Maternal polyunsaturated fatty acid concentrations during pregnancy and childhood liver fat accumulation. | 2022 | Details |
| A51125 | 35617705 | J Med Food | Partial Replacement of High-Fat Diet with Beef Tallow Attenuates Dyslipidemia and Endoplasmic Reticulum Stress in db/db Mice. | 2022 | Details |
| A51746 | 34409856 | Antioxid Redox Signal | Mitochondrial Adaptive Responses to Hypertriglyceridemia and Bioactive Lipids. | 2021 | Details |
| A51799 | 34016526 | Mol Genet Metab | Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes. | 2021 | Details |
| A51826 | 33900312 | Food Funct | Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet. | 2021 | Details |
| A51881 | 33487256 | Clin Nutr ESPEN | Nutraceuticals for the treatment of sarcopenia in chronic liver disease. | 2020 | Details |
| A51930 | 33144308 | mSystems | Correlations between α-Linolenic Acid-Improved Multitissue Homeostasis and Gut Microbiota in Mice Fed a High-Fat Diet. | 2020 | Details |
| A51996 | 32512788 | Antioxidants (Basel) | Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice. | 2020 | Details |
| A52012 | 32303571 | Dis Model Mech | A comprehensive study of phospholipid fatty acid rearrangements in metabolic syndrome: correlations with organ dysfunction. | 2020 | Details |
| A52068 | 31677841 | J Dairy Sci | Widespread basal cytochrome P450 expression in extrahepatic bovine tissues and isolated cells. | 2019 | Details |
| A52110 | 31091691 | Nutrients | Preventive Effects of the Marine Microalga Phaeodactylum tricornutum, Used as a Food Supplement, on Risk Factors Associated with Metabolic Syndrome in Wistar Rats. | 2019 | Details |
| A52166 | 30481177 | PLoS One | A metabolome-wide characterization of the diabetic phenotype in ZDF rats and its reversal by pioglitazone. | 2018 | Details |
| A52187 | 30308265 | Mol Cell Endocrinol | A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit model. | 2018 | Details |
| A52306 | 28826373 | Annu Rev Nutr | Fatty Acids and NLRP3 Inflammasome-Mediated Inflammation in Metabolic Tissues. | 2017 | Details |
| A52323 | 28661066 | NMR Biomed | Sexual dimorphism in hepatic lipids is associated with the evolution of metabolic status in mice. | 2017 | Details |
| A52523 | 26059381 | Nutrition | Conjugated linoleic acid reduces visceral and ectopic lipid accumulation and insulin resistance in chronic severe hypertriacylglycerolemia. | 2015 | Details |
| A52525 | 26042203 | Mol Metab | Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. | 2015 | Details |
| A52531 | 25916973 | Int J Dev Neurosci | Study of the serum levels of polyunsaturated fatty acids and the expression of related liver metabolic enzymes in a rat valproate-induced autism model. | 2015 | Details |
| A52731 | 22701720 | PLoS One | Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids. | 2012 | Details |
| A52736 | 22656374 | Prog Mol Biol Transl Sci | Nutrigenomics and nutrigenetics of ω3 polyunsaturated fatty acids. | 2012 | Details |
| A52770 | 22226887 | Biochim Biophys Acta | Oxidative stress and antioxidant therapy in cystic fibrosis. | 2011 | Details |
| A52831 | 21178610 | Curr Opin Clin Nutr Metab Care | Fatty acid regulation of hepatic lipid metabolism. | 2011 | Details |
| A52866 | 20487553 | BMC Gastroenterol | Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosis. | 2010 | Details |
| A52895 | 19852886 | Curr Atheroscler Rep | Cardiovascular disease-related genes and regulation by diet. | 2009 | Details |
| A52946 | 19148125 | Obesity (Silver Spring) | Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives. | 2009 | Details |
| A52960 | 18786125 | Am J Gastroenterol | The impact of diet on liver fibrosis and on response to interferon therapy in patients with HCV-related chronic hepatitis. | 2008 | Details |
| A52984 | 18333370 | Rom J Intern Med | Impact of obesity and omega-3 polyunsaturated fatty acids on fibrogenesis and responsiveness to antiviral therapy in chronic hepatitis C. | 2007 | Details |
| A53031 | 16996649 | Neurobiol Aging | A metabolic link between S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in Alzheimer's disease. | 2006 | Details |
| A53082 | 15485588 | Curr Atheroscler Rep | Diet, fatty acids, and regulation of genes important for heart disease. | 2004 | Details |
| A53090 | 15157941 | J Nutr Biochem | Effects of fish oil on hypertension, plasma lipids, and tumor necrosis factor-alpha in rats with sucrose-induced metabolic syndrome. | 2004 | Details |
| A53116 | 12585002 | Srp Arh Celok Lek | [Effect of a modified low protein and low fat diet on histologic changes and metabolism in kidneys in an experimental model of polycystic kidney disease]. | 2003 | Details |