Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02001 | 34533882 | Cancer Sci | Gut-liver axis-mediated mechanism of liver cancer: A special focus on the role of gut microbiota. | 2021 | Details |
| A02005 | 34533252 | J Biochem Mol Toxicol | Omarigliptin protects against nonalcoholic fatty liver disease by ameliorating oxidative stress and inflammation. | 2021 | Details |
| A02030 | 34526653 | Commun Biol | Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system. | 2021 | Details |
| A02031 | 34525916 | Curr Med Chem | Beneficial Effects of Dietary Polyphenols in the Prevention and Treatment of NAFLD: Cell-Signaling Pathways Underlying Health Effects. | 2022 | Details |
| A02034 | 34524919 | AIDS Patient Care STDS | Liver Fat, Adipose Tissue, and Body Composition Changes After Switching from a Protease Inhibitor or Efavirenz to Raltegravir. | 2021 | Details |
| A02036 | 34524512 | Histochem Cell Biol | Fat causes necrosis and inflammation in parenchymal cells in human steatotic liver. | 2021 | Details |
| A02064 | 34513923 | Front Mol Biosci | The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis. | 2021 | Details |
| A02106 | 34505434 | Se Pu | [Identification of LAMTOR1-regulated metabolites using ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry in malignant transformation of liver inflammation]. | 2021 | Details |
| A02107 | 34505423 | Endocrinol Diabetes Metab | Oxy210, a novel inhibitor of hedgehog and TGF-β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice. | 2021 | Details |
| A02112 | 34503151 | Cancers (Basel) | Host-Microbiota Interactions in Liver Inflammation and Cancer. | 2021 | Details |
| A02114 | 34502047 | Int J Mol Sci | Molecular and Pathophysiological Links between Metabolic Disorders and Inflammatory Bowel Diseases. | 2021 | Details |
| A02131 | 34495059 | Rev Assoc Med Bras (1992) | The association between serum uric acid to high density lipoprotein-cholesterol ratio and non-alcoholic fatty liver disease: the abund study. | 2021 | Details |
| A02133 | 34494384 | Hepatol Commun | Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis. | 2021 | Details |
| A02136 | 34492534 | Int Immunopharmacol | Antcin A alleviates pyroptosis and inflammatory response in Kupffercells of non-alcoholic fatty liver disease by targeting NLRP3. | 2021 | Details |
| A02142 | 34489524 | Int J Obes (Lond) | Leptin resistance before and after obesity: evidence that tissue glucose uptake underlies adipocyte enlargement and liver steatosis/steatohepatitis in Zucker rats from early-life stages. | 2021 | Details |
| A02153 | 34484560 | Oxid Med Cell Longev | Dietary Valine Ameliorated Gut Health and Accelerated the Development of Nonalcoholic Fatty Liver Disease of Laying Hens. | 2021 | Details |
| A02156 | 34483906 | Front Pharmacol | Metformin Alleviates Steatohepatitis in Diet-Induced Obese Mice in a SIRT1-Dependent Way. | 2021 | Details |
| A02157 | 34482357 | Med Sci Monit | Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02163 | 34479345 | Rev Med Chil | [The role of intestinal microbiota in the development of non-alcoholic fatty liver disease]. | 2021 | Details |
| A02165 | 34478730 | Arch Biochem Biophys | Luteolin alleviates non-alcoholic fatty liver disease in rats via restoration of intestinal mucosal barrier damage and microbiota imbalance involving in gut-liver axis. | 2021 | Details |
| A02177 | 34473596 | Can J Physiol Pharmacol | Hepatoprotective effect of trypsin/chymotrypsin against olanzapine-induced non-alcoholic steatohepatitis in rats. | 2021 | Details |
| A02178 | 34473313 | Methods Mol Biol | Therapeutic Effects of Resveratrol on Nonalcoholic Fatty Liver Disease Through Inflammatory, Oxidative Stress, Metabolic, and Epigenetic Modifications. | 2022 | Details |
| A02184 | 34470675 | Br J Nutr | Diet containing dehulled adlay ameliorates hepatic steatosis, inflammation and insulin resistance in rats with non-alcoholic fatty liver disease. | 2021 | Details |
| A02186 | 34469716 | Cell Rep | Myricetin supplementation decreases hepatic lipid synthesis and inflammation by modulating gut microbiota. | 2021 | Details |
| A02187 | 34469404 | J Clin Gastroenterol | Management of Cardiometabolic Complications in Patients With Nonalcoholic Fatty Liver Disease: A Review of the Literature With Recommendations. | 2021 | Details |
| A02199 | 34463983 | Periodontol 2000 | Periodontal disease-related nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: An emerging concept of oral-liver axis. | 2021 | Details |
| A02200 | 34463867 | Semin Immunopathol | Functional heterogeneity of CD4+ T cells in liver inflammation. | 2021 | Details |
| A02201 | 34462492 | Sci Rep | Deletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems. | 2021 | Details |
| A02202 | 34461919 | Lipids Health Dis | Low serum Maresin-1 levels are associated with non-alcoholic fatty liver disease: a cross-sectional study. | 2021 | Details |
| A02204 | 34461220 | Pharmacol Res | Identification of the anti-fungal drug fenticonazole nitrate as a novel PPARγ-modulating ligand with good therapeutic index: Structure-based screening and biological validation. | 2021 | Details |
| A02208 | 34459959 | Eur J Pediatr | Vitamin D and nonalcoholic fatty liver disease in children: a randomized controlled clinical trial. | 2021 | Details |
| A02212 | 34459004 | J Food Biochem | Chlorella vulgaris is an effective supplement in counteracting non-alcoholic fatty liver disease-related complications through modulation of dyslipidemia, insulin resistance, and inflammatory pathways. | 2021 | Details |
| A02243 | 34448436 | J Histochem Cytochem | Independent of Calorie Intake, Short-term Alternate-day Fasting Alleviates NASH, With Modulation of Markers of Lipogenesis, Autophagy, Apoptosis, and Inflammation in Rats. | 2021 | Details |
| A02251 | 34446271 | Clin Ther | Emerging and Established Therapeutic Approaches for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02254 | 34445644 | Int J Mol Sci | Resveratrol and Quercetin as Regulators of Inflammatory and Purinergic Receptors to Attenuate Liver Damage Associated to Metabolic Syndrome. | 2021 | Details |
| A02258 | 34445195 | Int J Mol Sci | Immunonano-Lipocarrier-Mediated Liver Sinusoidal Endothelial Cell-Specific RUNX1 Inhibition Impedes Immune Cell Infiltration and Hepatic Inflammation in Murine Model of NASH. | 2021 | Details |
| A02259 | 34444932 | Nutrients | The Other Side of Malnutrition in Inflammatory Bowel Disease (IBD): Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02260 | 34444811 | Nutrients | Curcumin and Biochemical Parameters in Metabolic-Associated Fatty Liver Disease (MAFLD)-A Review. | 2021 | Details |
| A02270 | 34440841 | Cells | Feedback Signaling between Cholangiopathies, Ductular Reaction, and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02277 | 34440260 | Biomedicines | The Histone Variant MacroH2A1 Impacts Circadian Gene Expression and Cell Phenotype in an In Vitro Model of Hepatocellular Carcinoma. | 2021 | Details |
| A02281 | 34439470 | Antioxidants (Basel) | Lupinus angustifolius Protein Hydrolysates Reduce Abdominal Adiposity and Ameliorate Metabolic Associated Fatty Liver Disease (MAFLD) in Western Diet Fed-ApoE-/- Mice. | 2021 | Details |
| A02305 | 34427662 | Clin Sci (Lond) | Exposure to cigarette smoke precipitates simple hepatosteatosis to NASH in high-fat diet fed mice by inducing oxidative stress. | 2021 | Details |
| A02307 | 34426178 | J Integr Med | Hepatic protective effects of Shenling Baizhu powder, a herbal compound, against inflammatory damage via TLR4/NLRP3 signalling pathway in rats with nonalcoholic fatty liver disease. | 2021 | Details |
| A02317 | 34422075 | Evid Based Complement Alternat Med | Antifibrotic Effects of Kangxian Ruangan Capsule on Rats with Nonalcoholic Fatty Liver Fibrosis and Hepatic Stellate Cells through Regulation of TGF-β and TLR4 Signaling Pathways. | 2021 | Details |
| A02327 | 34417588 | Nat Rev Endocrinol | Hepatic sexual dimorphism - implications for non-alcoholic fatty liver disease. | 2021 | Details |
| A02329 | 34416350 | Toxicology | Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent. | 2021 | Details |
| A02335 | 34414181 | Front Cell Dev Biol | Phytochemicals: Targeting Mitophagy to Treat Metabolic Disorders. | 2021 | Details |
| A02338 | 34411916 | Biomed Pharmacother | The role of mitochondria dysfunction and hepatic senescence in NAFLD development and progression. | 2021 | Details |
| A02352 | 34406209 | Braz J Med Biol Res | α,β-Amyrin prevents steatosis and insulin resistance in a high-fat diet-induced mouse model of NAFLD via the AMPK-mTORC1-SREBP1 signaling mechanism. | 2021 | Details |
| A02359 | 34403877 | Phytomedicine | A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating gut microbiota and reducing inflammation. | 2021 | Details |
| A02363 | 34402473 | Eur J Gastroenterol Hepatol | Glucagon is associated with NAFLD inflammatory progression in type 2 diabetes, not with NAFLD fibrotic progression. | 2021 | Details |
| A02374 | 34399486 | Food Res Int | Protective and ameliorating effects of probiotics against diet-induced obesity: A review. | 2021 | Details |
| A02379 | 34397640 | Eur J Gastroenterol Hepatol | The role of mean platelet volume in nonalcoholic fatty liver disease without cardiovascular comorbidities, obesity and diabetes mellitus. | 2021 | Details |
| A02380 | 34396890 | Arch Physiol Biochem | Hepatoprotection of capsaicin in alcoholic and non-alcoholic fatty liver diseases. | 2021 | Details |
| A02388 | 34393793 | Front Pharmacol | Extracts of Vine Tea Improve Diet-Induced Non-Alcoholic Steatohepatitis Through AMPK-LXRα Signaling. | 2021 | Details |
| A02392 | 34390865 | Cell Mol Gastroenterol Hepatol | E-Selectin-Dependent Inflammation and Lipolysis in Adipose Tissue Exacerbate Steatosis-to-NASH Progression via S100A8/9. | 2021 | Details |
| A02395 | 34389163 | Surgery | The role of bilio-pancreatic limb in nonalcoholic steatohepatitis improvement after duodenal-jejunal bypass in rats. | 2021 | Details |
| A02397 | 34387896 | Hepatology | Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice. | 2021 | Details |
| A02411 | 34383111 | Calcif Tissue Int | Neuregulin 4 Attenuates Osteoarthritis Progression by Inhibiting Inflammation and Apoptosis of Chondrocytes in Mice. | 2021 | Details |
| A02412 | 34382947 | Am J Gastroenterol | Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02416 | 34381983 | JHEP Rep | Histological activity despite normal ALT and IgG serum levels in patients with autoimmune hepatitis and cirrhosis. | 2021 | Details |
| A02418 | 34381196 | Nat Rev Endocrinol | GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease. | 2021 | Details |
| A02423 | 34375691 | Pharmacol Ther | Xyloketal B: A marine compound with medicinal potential. | 2021 | Details |
| A02425 | 34374782 | Inflamm Bowel Dis | The Impact of NAFLD on Hospitalization Outcomes in Patients With Inflammatory Bowel Diseases: Nationwide Analysis. | 2022 | Details |
| A02426 | 34374658 | J Physiol Pharmacol | Hesperidin, a novel candidate for the successful treatment of high fat diet plus ethanol-induced fatty liver disease in mice. | 2021 | Details |
| A02427 | 34374436 | J Pathol | The loss of histone deacetylase 4 in macrophages exacerbates hepatic and adipose tissue inflammation in male but not in female mice with diet-induced non-alcoholic steatohepatitis. | 2021 | Details |
| A02428 | 34374253 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | [Effects of GPR81 agonist on insulin resistance in rats with nonalcoholic fatty liver disease]. | 2021 | Details |
| A02434 | 34372491 | Viruses | Findings from Studies Are Congruent with Obesity Having a Viral Origin, but What about Obesity-Related NAFLD? | 2021 | Details |
| A02435 | 34371968 | Nutrients | The Emerging Role of Sfrp5 and Wnt5a in the Pathogenesis of Obesity: Implications for a Healthy Diet and Lifestyle. | 2021 | Details |
| A02465 | 34362228 | J Clin Med | Association of Body Composition and Sarcopenia with NASH in Obese Patients. | 2021 | Details |
| A02471 | 34360773 | Int J Mol Sci | Effect of Microbiome on Non-Alcoholic Fatty Liver Disease and the Role of Probiotics, Prebiotics, and Biogenics. | 2021 | Details |
| A02478 | 34359642 | Cancers (Basel) | The Emerging Factors and Treatment Options for NAFLD-Related Hepatocellular Carcinoma. | 2021 | Details |
| A02479 | 34359438 | Foods | Comparison of Egg Yolk and Soybean Phospholipids on Hepatic Fatty Acid Profile and Liver Protection in Rats Fed a High-Fructose Diet. | 2021 | Details |
| A02487 | 34356308 | Antioxidants (Basel) | Green Tea and Epigallocatechin Gallate (EGCG) for the Management of Nonalcoholic Fatty Liver Diseases (NAFLD): Insights into the Role of Oxidative Stress and Antioxidant Mechanism. | 2021 | Details |
| A02502 | 34349877 | Nutr Res Pract | Efficacy of nobiletin in improving hypercholesterolemia and nonalcoholic fatty liver disease in high-cholesterol diet-fed mice. | 2021 | Details |
| A02518 | 34343274 | Endocrinology | SGLT2 Inhibition for Cardiovascular Diseases, Chronic Kidney Disease, and NAFLD. | 2021 | Details |
| A02530 | 34339944 | Phytomedicine | Network pharmacology-based identification of significant pathway for protection of Yinhuang granule in a mice model of metabolic-associated fatty liver disease. | 2021 | Details |
| A02531 | 34339914 | Biomed Pharmacother | Molecular mechanisms and therapeutic implications of dihydromyricetin in liver disease. | 2021 | Details |
| A02537 | 34336366 | Liver Res | Adoptive transfer of Pfkfb3-disrupted hematopoietic cells to wild-type mice exacerbates diet-induced hepatic steatosis and inflammation. | 2020 | Details |
| A02538 | 34335826 | Evid Based Complement Alternat Med | Scolymus hispanicus (Golden Thistle) Ameliorates Hepatic Steatosis and Metabolic Syndrome by Reducing Lipid Accumulation, Oxidative Stress, and Inflammation in Rats under Hyperfatty Diet. | 2021 | Details |
| A02540 | 34335574 | Front Immunol | Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice. | 2021 | Details |
| A02544 | 34333285 | Biomed Pharmacother | Protective effects of p-coumaric acid against high-fat diet-induced metabolic dysregulation in mice. | 2021 | Details |
| A02546 | 34332979 | Life Sci | Dimethyl fumarate reduces oxidative stress, inflammation and fat deposition by modulation of Nrf2, SREBP-1c and NF-κB signaling in HFD fed mice. | 2021 | Details |
| A02555 | 34330452 | Clin Nutr ESPEN | Polyphenols in the prevention and treatment of non-alcoholic fatty liver disease: An update of preclinical and clinical studies. | 2021 | Details |
| A02557 | 34328687 | Liver Int | Zonation in NASH - A key paradigm for understanding pathophysiology and clinical outcomes. | 2021 | Details |
| A02562 | 34328087 | Biomed Pharmacother | Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats. | 2021 | Details |
| A02579 | 34324263 | Diabetes Obes Metab | Non-alcoholic fatty liver disease-related risk of cardiovascular disease and other cardiac complications. | 2021 | Details |
| A02585 | 34322121 | Front Immunol | CD8+ T Cells Involved in Metabolic Inflammation in Visceral Adipose Tissue and Liver of Transgenic Pigs. | 2021 | Details |
| A02589 | 34321839 | World J Gastroenterol | Incorporating mucosal-associated invariant T cells into the pathogenesis of chronic liver disease. | 2021 | Details |
| A02594 | 34321089 | Stem Cell Res Ther | Addressing the liver progenitor cell response and hepatic oxidative stress in experimental non-alcoholic fatty liver disease/non-alcoholic steatohepatitis using amniotic epithelial cells. | 2021 | Details |
| A02600 | 34315516 | Chin Med | Herbal therapy for ameliorating nonalcoholic fatty liver disease via rebuilding the intestinal microecology. | 2021 | Details |
| A02601 | 34314787 | Adv Drug Deliv Rev | Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis. | 2021 | Details |
| A02602 | 34314306 | Immunopharmacol Immunotoxicol | The effects of guluronic acid (G2013), a new emerging treatment, on inflammatory factors in nonalcoholic steatohepatitis patients under in vitro conditions. | 2021 | Details |
| A02603 | 34312684 | J Mol Med (Berl) | Lipid metabolism, inflammation, and foam cell formation in health and metabolic disorders: targeting mTORC1. | 2021 | Details |
| A02606 | 34311531 | Biomed Pharmacother | FTZ attenuates liver steatosis and fibrosis in the minipigs with type 2 diabetes by regulating the AMPK signaling pathway. | 2021 | Details |
| A02610 | 34310978 | Gastroenterology | TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial. | 2021 | Details |
| A02617 | 34308754 | Tissue Barriers | Effect of Adipose derived mesenchymal stem cells on multiple Organ Injuries in diet-induced obese mice. | 2021 | Details |
| A02622 | 34306045 | PPAR Res | Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-α/γ) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment Counteracts the High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02630 | 34303710 | Biochem Pharmacol | Pregnane X receptor exacerbates nonalcoholic fatty liver disease accompanied by obesity- and inflammation-prone gut microbiome signature. | 2021 | Details |
| A02635 | 34300227 | J Clin Med | Insulin Resistance Is Not Increased in Inflammatory Bowel Disease Patients but Is Related to Non-Alcoholic Fatty Liver Disease. | 2021 | Details |