Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A15120 | 29085788 | J Transl Int Med | Effect of Pentoxifylline on Histological Activity and Fibrosis of Nonalcoholic Steatohepatitis Patients: A One Year Randomized Control Trial. | 2017 | Details |
| A15126 | 31196637 | Ann Hepatol | Bile Acids in Nonalcoholic Fatty Liver Disease: New Concepts and Therapeutic Advances. | 2017 | Details |
| A15129 | 29083080 | Intern Med J | Underappreciation of non-alcoholic fatty liver disease by primary care clinicians: limited awareness of surrogate markers of fibrosis. | 2018 | Details |
| A15131 | 29083036 | Aliment Pharmacol Ther | Systematic review with meta-analysis: the significance of histological disease severity in lean patients with nonalcoholic fatty liver disease. | 2017 | Details |
| A15132 | 29082798 | Expert Rev Gastroenterol Hepatol | The use of obeticholic acid for the management of non-viral liver disease: current clinical practice and future perspectives. | 2017 | Details |
| A15135 | 29080343 | Ann Hepatol | Bile Acids in Nonalcoholic Fatty Liver Disease: New Concepts and therapeutic advances. | 2017 | Details |
| A15140 | 29077272 | J Cell Mol Med | Inhibition of MD2-dependent inflammation attenuates the progression of non-alcoholic fatty liver disease. | 2017 | Details |
| A15143 | 29076589 | APMIS | Non-alcoholic fatty liver disease - histological scoring systems: a large cohort single-center, evaluation study. | 2017 | Details |
| A15148 | 29073252 | PLoS One | Severity of coronary artery disease is associated with non-alcoholic fatty liver dis-ease: A single-blinded prospective mono-center study. | 2017 | Details |
| A15158 | 29067443 | Mol Med Rep | Role of ADAMTS13 in diet-induced liver steatosis. | 2017 | Details |
| A15159 | 29067150 | Frontline Gastroenterol | Care standards for non-alcoholic fatty liver disease in the United Kingdom 2016: a cross-sectional survey. | 2017 | Details |
| A15163 | 29066462 | Am J Physiol Endocrinol Metab | Genetic ablation of Cyp8b1 preserves host metabolic function by repressing steatohepatitis and altering gut microbiota composition. | 2017 | Details |
| A15164 | 29066349 | Biochem Biophys Res Commun | Dihydroceramide is a key metabolite that regulates autophagy and promotes fibrosis in hepatic steatosis model. | 2017 | Details |
| A15165 | 29065724 | Exp Biol Med (Maywood) | Microcirculatory disturbances and cellular changes during progression of hepatic steatosis to liver tumors. | 2017 | Details |
| A15166 | 29065699 | Ann Clin Biochem | Performance of autotaxin as a serum marker for liver fibrosis. | 2017 | Details |
| A15176 | 29063072 | Chronic Dis Transl Med | Potential role of thymosin beta 4 in the treatment of nonalcoholic fatty liver disease. | 2017 | Details |
| A15179 | 29060526 | Annu Int Conf IEEE Eng Med Biol Soc | The influence of hepatic steatosis on the evaluation of fibrosis with non-alcoholic fatty liver disease by acoustic radiation force impulse. | 2017 | Details |
| A15181 | 29059699 | Hepatol Res | Identification of the genomic region under epigenetic regulation during non-alcoholic fatty liver disease progression. | 2017 | Details |
| A15184 | 29058997 | Annu Rev Pharmacol Toxicol | Nonalcoholic Steatohepatitis (NASH) and Hepatic Fibrosis: Emerging Therapies. | 2017 | Details |
| A15185 | 29058029 | Eur Radiol | Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease correlate with epicardial fat volume in type 2 diabetes: A prospective study. | 2017 | Details |
| A15192 | 29056013 | Zhonghua Gan Zang Bing Za Zhi | [Clinical study of non-alcoholic fatty liver disease and its combined the chronic HBV infection]. | 2017 | Details |
| A15193 | 29056000 | Zhonghua Gan Zang Bing Za Zhi | [The progress of studying the mechanisms of immune cells in the regulation of non-alcoholic fatty liver diseases]. | 2017 | Details |
| A15194 | 29055990 | Zhonghua Gan Zang Bing Za Zhi | [Neovascularization aggravated hepatic fibrosis in combined hypoxia NASH rat model]. | 2017 | Details |
| A15195 | 29055928 | Ann Hepatol | New Onset Diabetes and Non-Alcoholic Fatty Liver Disease after Liver Transplantation. | 2018 | Details |
| A15197 | 29055919 | Ann Hepatol | The Expression of PNPLA3 Polymorphism could be the Key for Severe Liver Disease in NAFLD in Hispanic Population. | 2018 | Details |
| A15201 | 29055669 | Surg Obes Relat Dis | Impact of bariatric surgery on outcomes of patients with nonalcoholic fatty liver disease: a nationwide inpatient sample analysis, 2004-2012. | 2017 | Details |
| A15211 | 29045180 | AJR Am J Roentgenol | Quantitative Liver MRI-Biopsy Correlation in Pediatric and Young Adult Patients With Nonalcoholic Fatty Liver Disease: Can One Be Used to Predict the Other? | 2017 | Details |
| A15216 | 29040984 | Dig Dis | Ability of Cytokeratin-18 Fragments and FIB-4 Index to Diagnose Overall and Mild Fibrosis Nonalcoholic Steatohepatitis in Japanese Nonalcoholic Fatty Liver Disease Patients. | 2017 | Details |
| A15221 | 29038049 | Biochim Biophys Acta Mol Basis Dis | Inhibition of EGFR attenuates fibrosis and stellate cell activation in diet-induced model of nonalcoholic fatty liver disease. | 2017 | Details |
| A15238 | 29028281 | Liver Int | Usefulness of the index of NASH - ION for the diagnosis of steatohepatitis in patients with non-alcoholic fatty liver: An external validation study. | 2017 | Details |
| A15244 | 29025246 | Pol J Pathol | Vaspin mRNA levels in the liver of morbidly obese women with nonalcoholic fatty liver disease. | 2017 | Details |
| A15245 | 29025245 | Pol J Pathol | Hepatic chemerin mRNA in morbidly obese patients with nonalcoholic fatty liver disease. | 2017 | Details |
| A15249 | 29024407 | Aging Cell | Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/DGAT1 pathway. | 2017 | Details |
| A15252 | 29023783 | J Cell Physiol | Melatonin application in targeting oxidative-induced liver injuries: A review. | 2017 | Details |
| A15257 | 29022011 | Heliyon | Placental extract ameliorates non-alcoholic steatohepatitis (NASH) by exerting protective effects on endothelial cells. | 2017 | Details |
| A15260 | 29018509 | Oxid Med Cell Longev | circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis. | 2017 | Details |
| A15270 | 28993096 | Transl Res | Altered expression of MALAT1 lncRNA in nonalcoholic steatohepatitis fibrosis regulates CXCL5 in hepatic stellate cells. | 2017 | Details |
| A15274 | 28990251 | J Gastroenterol Hepatol | Waist-to-calf circumstance ratio is an independent predictor of hepatic steatosis and fibrosis in patients with type 2 diabetes. | 2018 | Details |
| A15278 | 28989564 | World J Hepatol | Diffusion weighted magnetic resonance imaging of liver: Principles, clinical applications and recent updates. | 2017 | Details |
| A15280 | 28989092 | J Hepatol | Advanced liver fibrosis but not steatosis is independently associated with albuminuria in Chinese patients with type 2 diabetes. | 2017 | Details |
| A15281 | 28988798 | Free Radic Biol Med | Differential carbonylation of proteins in end-stage human fatty and nonfatty NASH. | 2017 | Details |
| A15285 | 28987260 | Clin Liver Dis | Treatment Strategies for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15286 | 28986720 | Curr Atheroscler Rep | The Role of Metabolic Surgery in Non-alcoholic Steatohepatitis Improvement. | 2017 | Details |
| A15294 | 28981521 | PLoS One | Nonalcoholic fatty liver disease is associated with an increased risk of heart block in hospitalized patients with type 2 diabetes mellitus. | 2017 | Details |
| A15299 | 28975533 | Indian J Gastroenterol | Association of single nucleotide polymorphism at PNPLA3 with fatty liver, steatohepatitis, and cirrhosis of liver. | 2017 | Details |
| A15304 | 28973532 | Toxicol Sci | Editor's Highlight: PCB126 Exposure Increases Risk for Peripheral Vascular Diseases in a Liver Injury Mouse Model. | 2017 | Details |
| A15305 | 28972878 | Discov Med | Role of nutrition, gene polymorphism, and gut microbiota in non-alcoholic fatty liver disease. | 2017 | Details |
| A15313 | 28970836 | Front Immunol | Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease. | 2017 | Details |
| A15314 | 28970532 | Sci Rep | Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation. | 2017 | Details |
| A15316 | 28970148 | Clin Gastroenterol Hepatol | Racial and Ethnic Disparities in Nonalcoholic Fatty Liver Disease Prevalence, Severity, and Outcomes in the United States: A Systematic Review and Meta-analysis. | 2017 | Details |
| A15317 | 28970146 | Clin Gastroenterol Hepatol | Association Between Hepatic Steatosis, Measured by Controlled Attenuation Parameter, and Fibrosis Burden in Chronic Hepatitis B. | 2017 | Details |
| A15319 | 28969511 | Stress | Interactive effects of chronic stress and a high-sucrose diet on nonalcoholic fatty liver in young adult male rats. | 2017 | Details |
| A15321 | 28968053 | Practitioner | Improving the identification and monitoring of cirrhosis. | 2016 | Details |
| A15322 | 28967709 | ESC Heart Fail | Liver fibrosis score predicts mortality in heart failure patients with preserved ejection fraction. | 2017 | Details |
| A15326 | 28965986 | Matrix Biol | Deficiency of periostin impairs liver regeneration in mice after partial hepatectomy. | 2017 | Details |
| A15327 | 28965313 | Obes Surg | Significant Liver-Related Morbidity After Bariatric Surgery and Its Reversal-a Case Series. | 2018 | Details |
| A15335 | 28962213 | Exp Ther Med | Effects of telmisartan on improving leptin resistance and inhibiting hepatic fibrosis in rats with non-alcoholic fatty liver disease. | 2017 | Details |
| A15340 | 28956824 | Nutrients | Translational Aspects of Diet and Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A15342 | 28955967 | Biochem Biophys Rep | Quantitative imaging of fibrotic and morphological changes in liver of non-alcoholic steatohepatitis (NASH) model mice by second harmonic generation (SHG) and auto-fluorescence (AF) imaging using two-photon excitation microscopy (TPEM). | 2016 | Details |
| A15350 | 28953222 | Nutrients | Animal Models of Nonalcoholic Fatty Liver Disease-A Starter's Guide. | 2017 | Details |
| A15351 | 28952917 | Exp Clin Transplant | Accuracy of Noninvasive Fibrosis Scores in Predicting the Presence of Fibrosis in Patients after Liver Transplantation. | 2017 | Details |
| A15355 | 28948754 | Minerva Gastroenterol Dietol | Histopathology, grading and staging of nonalcoholic fatty liver disease. | 2017 | Details |
| A15356 | 28948665 | J Paediatr Child Health | Performance of fibrosis prediction scores in paediatric non-alcoholic fatty liver disease. | 2017 | Details |
| A15357 | 28948002 | Oncotarget | Linking atrial fibrillation with non-alcoholic fatty liver disease: potential common therapeutic targets. | 2017 | Details |
| A15360 | 28947134 | J Formos Med Assoc | Elevated body mass index is a risk factor associated with possible liver cirrhosis across different etiologies of chronic liver disease. | 2017 | Details |
| A15361 | 28946547 | Cancer Biomark | Pioglitazone suppresses inflammation and fibrosis in nonalcoholic fatty liver disease by down-regulating PDGF and TIMP-2: Evidence from in vitro study. | 2017 | Details |
| A15365 | 28944671 | J Proteome Res | Prioritizing Popular Proteins in Liver Cancer: Remodelling One-Carbon Metabolism. | 2017 | Details |
| A15370 | 28941732 | Exp Mol Pathol | The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma. | 2017 | Details |
| A15372 | 28941597 | Metabolism | Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. | 2017 | Details |
| A15375 | 28940700 | Hepatology | Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis. | 2018 | Details |
| A15382 | 28936407 | J Clin Transl Hepatol | Current Modalities of Fibrosis Assessment in Non-alcoholic Fatty Liver Disease. | 2017 | Details |
| A15383 | 28936403 | J Clin Transl Hepatol | Non-alcoholic Fatty Liver Disease in Lean Subjects: Characteristics and Implications. | 2017 | Details |
| A15384 | 28936398 | J Clin Transl Hepatol | Vitamin D Is Associated with Severity and Mortality of Non-alcoholic Fatty Liver Disease: A US Population-based Study. | 2017 | Details |
| A15400 | 28930194 | Nutrients | Developmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System. | 2017 | Details |
| A15401 | 28930164 | Cancers (Basel) | Liver Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells. | 2017 | Details |
| A15404 | 28927302 | Scand J Gastroenterol | IGFBP-1 and IGF-I as markers for advanced fibrosis in NAFLD - a pilot study. | 2017 | Details |
| A15412 | 28924922 | J Gastrointest Surg | Assessing the Non-tumorous Liver: Implications for Patient Management and Surgical Therapy. | 2017 | Details |
| A15419 | 28922680 | Horm Metab Res | Pivotal Role of TNF-α in the Development and Progression of Nonalcoholic Fatty Liver Disease in a Murine Model. | 2017 | Details |
| A15423 | 28919979 | BMC Obes | Reversal of fibrosis in patients with nonalcoholic steatohepatosis after gastric bypass surgery. | 2017 | Details |
| A15425 | 28918882 | J Pediatr | Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys. | 2017 | Details |
| A15427 | 31225436 | Cell Stress | Senescence explains age- and obesity-related liver steatosis. | 2017 | Details |
| A15433 | 28914448 | Aliment Pharmacol Ther | Significant burden of nonalcoholic fatty liver disease with advanced fibrosis in the US: a cross-sectional analysis of 2011-2014 National Health and Nutrition Examination Survey. | 2017 | Details |
| A15434 | 28914407 | Endocrine | Association of fetuin B with markers of liver fibrosis in nonalcoholic fatty liver disease. | 2017 | Details |
| A15436 | 28913408 | Cell Mol Gastroenterol Hepatol | Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis. | 2017 | Details |
| A15437 | 28906458 | Nutrients | Combination of Hypertension Along with a High Fat and Cholesterol Diet Induces Severe Hepatic Inflammation in Rats via a Signaling Network Comprising NF-κB, MAPK, and Nrf2 Pathways. | 2017 | Details |
| A15443 | 28904866 | FEBS Open Bio | IMM-H007, a new therapeutic candidate for nonalcoholic fatty liver disease, improves hepatic steatosis in hamsters fed a high-fat diet. | 2017 | Details |
| A15454 | 28899857 | Am J Physiol Endocrinol Metab | High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine. | 2017 | Details |
| A15457 | 28898507 | Liver Int | Growth differentiation factor 15 predicts advanced fibrosis in biopsy-proven non-alcoholic fatty liver disease. | 2017 | Details |
| A15459 | 28895929 | Nutrients | Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis. | 2017 | Details |
| A15460 | 28895919 | Int J Mol Sci | NAFLD: Is There Anything New under the Sun? | 2017 | Details |
| A15462 | 28895242 | Int J Exp Pathol | Hepatocellular carcinoma in a mouse model fed a choline-deficient, L-amino acid-defined, high-fat diet. | 2017 | Details |
| A15468 | 28892558 | Hepatology | The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial. | 2017 | Details |
| A15472 | 28890481 | Endocr J | Free testosterone concentration is inversely associated with markers of liver fibrosis in men with type 2 diabetes mellitus. | 2017 | Details |
| A15478 | 28883965 | Trop Dis Travel Med Vaccines | Hepatic steatosis in HCV-infected persons in the direct-acting antiviral era. | 2016 | Details |
| A15483 | 28880885 | PLoS One | Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children. | 2017 | Details |
| A15486 | 28880053 | Panminerva Med | Liver fibrosis: the 2017 state of art. | 2017 | Details |
| A15496 | 28875689 | Minerva Gastroenterol Dietol | Liver fibrosis in the context of nonalcoholic steatohepatitis: the role of adipokines. | 2017 | Details |
| A15497 | 28875438 | Obes Surg | Non-invasive Evaluation of NAFLD with Indocyanine Green Clearance Test: a Preliminary Study in Morbidly Obese Patients Undergoing Bariatric Surgery. | 2018 | Details |
| A15498 | 28875318 | Eur J Nutr | Influence of gut microbiota on the development and progression of nonalcoholic steatohepatitis. | 2017 | Details |
| A15500 | 28874443 | J Lipid Res | Amelioration of diet-induced steatohepatitis in mice following combined therapy with ASO-Fsp27 and fenofibrate. | 2017 | Details |