Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A30624 | 32093102 | Int J Mol Sci | Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia-Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-κB, and Oxidative Stress. | 2020 | Details |
| A30637 | 32062834 | J Cell Commun Signal | Neutralizing antibody against osteopontin attenuates non-alcoholic steatohepatitis in mice. | 2020 | Details |
| A30654 | 32039401 | JHEP Rep | Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis. | 2019 | Details |
| A30665 | 32025605 | Hepatol Commun | Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice. | 2019 | Details |
| A30666 | 32025163 | J Clin Exp Hepatol | Characterisation of the Serum Metabolic Signature of Cholangiocarcinoma in a United Kingdom Cohort. | 2019 | Details |
| A30670 | 32021639 | Nutr Metab (Lond) | Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis. | 2020 | Details |
| A30684 | 31996485 | JCI Insight | ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model. | 2020 | Details |
| A30701 | 31940797 | Int J Mol Sci | Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases. | 2020 | Details |
| A30722 | 31909359 | Hepatol Commun | Farnesoid X Receptor Agonism, Acetyl-Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model. | 2019 | Details |
| A30778 | 31798280 | World J Gastroenterol | Serum amyloid A levels in patients with liver diseases. | 2019 | Details |
| A30810 | 31747961 | Stem Cell Res Ther | Treatment with adipose tissue-derived mesenchymal stem cells exerts anti-diabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic rats. | 2019 | Details |
| A30824 | 31717968 | Int J Mol Sci | The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2. | 2019 | Details |
| A30825 | 31717307 | Cancers (Basel) | The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma. | 2019 | Details |
| A30854 | 31667206 | Regen Ther | Mesenchymal stem cells cultured under hypoxic conditions had a greater therapeutic effect on mice with liver cirrhosis compared to those cultured under normal oxygen conditions. | 2019 | Details |
| A30893 | 31610032 | Hepatology | Yes-Associated Protein in Kupffer Cells Enhances the Production of Proinflammatory Cytokines and Promotes the Development of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A30905 | 31585800 | Mol Ther | MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury. | 2019 | Details |
| A30947 | 31497744 | Hepatol Commun | Characterization of Cellular Sources and Circulating Levels of Extracellular Vesicles in a Dietary Murine Model of Nonalcoholic Steatohepatitis. | 2019 | Details |
| A30997 | 31416250 | Cancers (Basel) | Multi-Drug/Gene NASH Therapy Delivery and Selective Hyperspectral NIR Imaging Using Chirality-Sorted Single-Walled Carbon Nanotubes. | 2019 | Details |
| A31059 | 31294056 | Data Brief | Transcriptomics data of a human in vitro model of non-alcoholic steatohepatitis exposed to elafibranor. | 2019 | Details |
| A31070 | 31277929 | Semin Arthritis Rheum | Associations of lumbar scoliosis with presentation of suspected early axial spondyloarthritis. | 2019 | Details |
| A31102 | 31222801 | Hepatology | Hepatocyte TNF Receptor-Associated Factor 6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lysine 6-Linked Polyubiquitination of Apoptosis Signal-Regulating Kinase 1. | 2019 | Details |
| A31125 | 31201554 | Handb Exp Pharmacol | Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists. | 2019 | Details |
| A31241 | 30972180 | Am J Transl Res | Development and validation of an in vitro 3D model of NASH with severe fibrotic phenotype. | 2019 | Details |
| A31251 | 30962734 | J Ginseng Res | Fermented ginseng, GBCK25, ameliorates steatosis and inflammation in nonalcoholic steatohepatitis model. | 2017 | Details |
| A31263 | 30949049 | Front Pharmacol | The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis. | 2019 | Details |
| A31314 | 30813339 | Nutrients | Interesterified Fats Induce Deleterious Effects on Adipose Tissue and Liver in LDLr-KO Mice. | 2019 | Details |
| A31322 | 30802511 | Life Sci | The effect of enterolactone on liver lipid precursors of inflammation. | 2019 | Details |
| A31375 | 30705600 | Diabetes Metab Syndr Obes | Effects of duodenal-jejunal bypass surgery in ameliorating nonalcoholic steatohepatitis in diet-induced obese rats. | 2019 | Details |
| A31384 | 30675167 | Stem Cells Int | Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats. | 2018 | Details |
| A31444 | 30556039 | Hepatol Commun | Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr-/-.Leiden Mice. | 2018 | Details |
| A31455 | 30523261 | Nat Commun | An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma. | 2018 | Details |
| A31546 | 30309020 | Int J Mol Sci | Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver. | 2018 | Details |
| A31583 | 30248539 | Biomed Pharmacother | Effect of silibinin on CFLAR-JNK pathway in oleic acid-treated HepG2 cells. | 2018 | Details |
| A31618 | 30190373 | Mol Cell Proteomics | Endoglycosidase S Enables a Highly Simplified Clinical Chemistry Procedure for Direct Assessment of Serum IgG Undergalactosylation in Chronic Inflammatory Disease. | 2018 | Details |
| A31662 | 30084733 | J Neurotrauma | Dietary Green Tea Extract Prior to Spinal Cord Injury Prevents Hepatic Iron Overload but Does Not Improve Chronic Hepatic and Spinal Cord Pathology in Rats. | 2018 | Details |
| A31673 | 30057822 | Int J Hepatol | Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress. | 2018 | Details |
| A31684 | 30046568 | Hepatobiliary Surg Nutr | A fermented mixed tea made with camellia (Camellia japonica) and third-crop green tea leaves prevents nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet. | 2018 | Details |
| A31747 | 29933033 | Pharmacol Ther | Progress and challenges of selective Farnesoid X Receptor modulation. | 2018 | Details |
| A31765 | 29900399 | Data Brief | The effect of synbiotics Bifidobacterium infantis and milk oligosaccharides on shaping gut microbiota community structure and NASH treatment. | 2018 | Details |
| A31819 | 29761169 | Hepatol Commun | Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet-induced mouse model of nonalcoholic steatohepatitis. | 2018 | Details |
| A31902 | 29593846 | Int J Physiol Pathophysiol Pharmacol | New insights into Nod-like receptors (NLRs) in liver diseases. | 2018 | Details |
| A31933 | 29527177 | Front Physiol | Key Inflammatory Processes in Human NASH Are Reflected in Ldlr-/-.Leiden Mice: A Translational Gene Profiling Study. | 2018 | Details |
| A31939 | 29515450 | Front Pharmacol | Chymase Inhibitor as a Novel Therapeutic Agent for Non-alcoholic Steatohepatitis. | 2018 | Details |
| A31982 | 29404462 | Hepatol Commun | Intermittent hypoxia is a proinflammatory stimulus resulting in IL-6 expression and M1 macrophage polarization. | 2017 | Details |
| A32019 | 30906835 | Genes Dis | Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood. | 2018 | Details |
| A32060 | 29278707 | Biochem Biophys Res Commun | Metformin ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and GPR91 inhibition. | 2017 | Details |
| A32111 | 29180269 | Exp Mol Pathol | Dysregulation of antioxidant responses in patients diagnosed with concomitant Primary Sclerosing Cholangitis/Inflammatory Bowel Disease. | 2017 | Details |
| A32163 | 29075339 | Exp Ther Med | Berberine ameliorates non-alcoholic steatohepatitis in ApoE-/- mice. | 2017 | Details |
| A32164 | 29068700 | Nutr Cancer | Silibinin Reduces the Impact of Obesity on Invasive Liver Cancer. | 2017 | Details |
| A32178 | 29046730 | Diabetol Metab Syndr | Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome. | 2017 | Details |
| A32265 | 28821460 | Nitric Oxide | Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro. | 2017 | Details |
| A32276 | 28808187 | J Biomed Res | G-Aminobutyric acid promotes methionine-choline deficient diet-induced nonalcoholic steatohepatitis. | 2016 | Details |
| A32297 | 28768902 | JCI Insight | Mixed-lineage kinase 3 pharmacological inhibition attenuates murine nonalcoholic steatohepatitis. | 2017 | Details |
| A32351 | 28663673 | J Clin Exp Hepatol | Spontaneous Bacterial Peritonitis by Burkholderia cepacia Complex: A Rare, Difficult to Treat Infection in Decompensated Cirrhotic Patients. | 2016 | Details |
| A32421 | 28487545 | Nat Rev Gastroenterol Hepatol | Mechanisms of hepatic stellate cell activation. | 2017 | Details |
| A32468 | 28365916 | Dig Dis Sci | Pigment Epithelium-Derived Factor (PEDF) Prevents Hepatic Fat Storage, Inflammation, and Fibrosis in Dietary Steatohepatitis of Mice. | 2017 | Details |
| A32521 | 28214071 | Trends Endocrinol Metab | Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation. | 2017 | Details |
| A32537 | 28167852 | Mediators Inflamm | Salvia-Nelumbinis Naturalis Formula Improved Inflammation in LPS Stressed Macrophages via Upregulating MicroRNA-152. | 2017 | Details |
| A32582 | 28066964 | Hepatol Res | Mechanisms of the prevention and inhibition of the progression and development of non-alcoholic steatohepatitis by genetic and pharmacological decoy receptor 3 supplementation. | 2017 | Details |
| A32658 | 27816611 | Free Radic Biol Med | Vitamin E: Emerging aspects and new directions. | 2016 | Details |
| A32689 | 27760889 | J Biomed Res | G-Aminobutyric acid promotes methionine-choline deficient diet-induced nonalcoholic steatohepatitis. | 2016 | Details |
| A32721 | 29922669 | Inflamm Intest Dis | Increased Intestinal Permeability and Decreased Barrier Function: Does It Really Influence the Risk of Inflammation? | 2016 | Details |
| A32722 | 27685150 | PLoS One | Macrophage Stimulating Protein Enhances Hepatic Inflammation in a NASH Model. | 2016 | Details |
| A32734 | 27652492 | J Med Chem | Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders. | 2016 | Details |
| A32757 | 27572743 | Curr Drug Targets | Hydrogen Sulfide and Inflammatory Joint Diseases. | 2017 | Details |
| A32768 | 27533769 | Braz J Med Biol Res | Transient elastography and APRI score: looking at false positives and false negatives. Diagnostic performance and association to fibrosis staging in chronic hepatitis C. | 2016 | Details |
| A32824 | 27347340 | Am J Transl Res | The effect of polyene phosphatidyl choline intervention on nonalcoholic steatohepatitis and related mechanism. | 2016 | Details |
| A32838 | 27315400 | Mol Med Rep | Effects of bamboo salt and its component, hydrogen sulfide, on enhancing immunity. | 2016 | Details |
| A32879 | 27182456 | J Clin Cell Immunol | Role of Serum Biomarkers in Early Detection of Non-Alcoholic Steatohepatitis and Fibrosis in West Virginian Children. | 2016 | Details |
| A32891 | 27158326 | Am J Transl Res | Ameliorative effects of glycine in an experimental nonalcoholic steatohepatitis and its correlation between TREM-1 and TREM-2. | 2016 | Details |
| A32939 | 27048430 | J Math Biol | Optimal vaccination strategies and rational behaviour in seasonal epidemics. | 2016 | Details |
| A32956 | 26992446 | Hepatol Res | Non-alcoholic steatohepatitis-associated hepatic fibrosis and hepatocellular carcinoma in a combined mouse model of genetic modification and dietary challenge. | 2016 | Details |
| A33000 | 26885230 | Int J Clin Exp Med | Preclinical analysis of nonsteroidal anti-inflammatory drug usefulness for the simultaneous prevention of steatohepatitis, atherosclerosis and hyperlipidemia. | 2015 | Details |
| A33018 | 26856696 | J Neuroinflammation | Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases. | 2016 | Details |
| A33044 | 26799785 | Hepatology | A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice. | 2016 | Details |
| A33050 | 26784524 | J Immunol Methods | Adeno associated viral-mediated intraosseous labeling of bone marrow derived cells for CNS tracking. | 2016 | Details |
| A33064 | 26758786 | Nat Rev Gastroenterol Hepatol | Immunology in the liver--from homeostasis to disease. | 2016 | Details |
| A33076 | 26734629 | Hepatobiliary Surg Nutr | Detection of carcinogenic etheno-DNA adducts in children and adolescents with non-alcoholic steatohepatitis (NASH). | 2015 | Details |
| A33123 | 26639395 | J Hepatol | Decreased expression of the glucocorticoid receptor-GILZ pathway in Kupffer cells promotes liver inflammation in obese mice. | 2015 | Details |
| A33140 | 26610473 | Int J Mol Sci | Inhibitory Effect of Gardenoside on Free Fatty Acid-Induced Steatosis in HepG2 Hepatocytes. | 2015 | Details |
| A33142 | 26605278 | Hepatobiliary Surg Nutr | Accumulated myeloid-derived suppressor cells demonstrate distinct phenotypes and functions in two non-alcoholic steatohepatitis mouse models. | 2015 | Details |
| A33163 | 26576191 | Evid Based Complement Alternat Med | Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats. | 2015 | Details |
| A33190 | 26504479 | Evid Based Complement Alternat Med | Effects of Soothing Liver and Invigorating Spleen Recipes on the IKKβ-NF-κB Signaling Pathway in Kupffer Cells of Nonalcoholic Steatohepatitis Rats. | 2015 | Details |
| A33217 | 26436354 | Ann Hepatol | Diagnostic performance of controlled attenuation parameter for predicting steatosis grade in chronic hepatitis B. | 2016 | Details |
| A33266 | 26334449 | Int J Rheum Dis | APLAR rheumatoid arthritis treatment recommendations. | 2015 | Details |
| A33316 | 26246839 | Evid Based Complement Alternat Med | Genistein Attenuates Nonalcoholic Steatohepatitis and Increases Hepatic PPARγ in a Rat Model. | 2015 | Details |
| A33318 | 26244065 | World J Hepatol | Cross talk of the immune system in the adipose tissue and the liver in non-alcoholic steatohepatitis: Pathology and beyond. | 2015 | Details |
| A33342 | 26192243 | Zhonghua Gan Zang Bing Za Zhi | [Mechanism of expression of the Src family kinases (Fgr, Hck, Lyn) and SSeCKS in non-alcoholic steatohepatitis]. | 2015 | Details |
| A33353 | 26162843 | Handb Exp Pharmacol | Phosphinodithioate and Phosphoramidodithioate Hydrogen Sulfide Donors. | 2015 | Details |
| A33364 | 26123664 | Cancer Lett | Role of chemokine pathways in hepatobiliary cancer. | 2015 | Details |
| A33370 | 26111628 | Mol Neurobiol | Hydrogen Sulfide Ameliorates Early Brain Injury Following Subarachnoid Hemorrhage in Rats. | 2015 | Details |
| A33377 | 26101777 | Biomed Res Int | The Sea Lamprey as an Etiological Model for Biliary Atresia. | 2015 | Details |
| A33441 | 25979814 | Aging (Albany NY) | High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice. | 2015 | Details |
| A33463 | 25943712 | Hepatol Res | Morbidly obese patient with non-alcoholic steatohepatitis-related cirrhosis who died from sepsis caused by dental infection of Porphyromonas gingivalis: A case report. | 2015 | Details |
| A33484 | 25903417 | Handb Exp Pharmacol | Immune Cells and Metabolism. | 2016 | Details |
| A33489 | 25888871 | Lipids Health Dis | High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice. | 2015 | Details |
| A33505 | 25848483 | World J Hepatol | Prevention of hepatocellular carcinoma: Focusing on antioxidant therapy. | 2015 | Details |
| A33545 | 25756900 | Mar Environ Res | Histopathological assessment of liver and gonad pathology in continental slope fish from the northeast Atlantic Ocean. | 2015 | Details |
| A33583 | 25654228 | Int J Mol Sci | Reduction of oxidative stress attenuates lipoapoptosis exacerbated by hypoxia in human hepatocytes. | 2015 | Details |
| A33643 | 25532502 | Dig Dis Sci | Curcumin targets multiple pathways to halt hepatic stellate cell activation: updated mechanisms in vitro and in vivo. | 2014 | Details |