Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A15886 | 28670854 | J Gastroenterol Hepatol | Honokiol attenuates diet-induced non-alcoholic steatohepatitis by regulating macrophage polarization through activating peroxisome proliferator-activated receptor γ. | 2018 | Details |
| A15897 | 28664744 | Bratisl Lek Listy | Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage. | 2017 | Details |
| A15900 | 28662136 | PLoS One | Influence of nicotine on choline-deficient, L-amino acid-defined diet-induced non-alcoholic steatohepatitis in rats. | 2017 | Details |
| A15903 | 28660148 | J Clin Transl Hepatol | Evaluation of Biomarkers in Egyptian Patients with Different Grades of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A15904 | 28659437 | Sci Transl Med | Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β. | 2017 | Details |
| A15906 | 28658094 | Medicine (Baltimore) | Multimorbidity and polypharmacy in diabetic patients with NAFLD: Implications for disease severity and management. | 2017 | Details |
| A15912 | 28655690 | Pak J Pharm Sci | Metformin HCl has curative effect on rebuilding of ventricular diastolic functions in high-fat-diet fed rats. | 2017 | Details |
| A15917 | 28652891 | World J Hepatol | Non-alcoholic fatty liver disease: An expanded review. | 2017 | Details |
| A15922 | 28651300 | Gut Liver | Noninvasive Assessment of Advanced Fibrosis Based on Hepatic Volume in Patients with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A15923 | 28650518 | Liver Int | A simple in silico strategy identifies candidate biomarkers for the diagnosis of liver fibrosis in morbidly obese subjects. | 2017 | Details |
| A15926 | 28647765 | Abdom Radiol (NY) | Epidemiology of hepatocellular carcinoma: target population for surveillance and diagnosis. | 2018 | Details |
| A15934 | 28645738 | J Hepatol | Human germline hedgehog pathway mutations predispose to fatty liver. | 2017 | Details |
| A15935 | 28644356 | J Pediatr Gastroenterol Nutr | Low Hepatic Tissue Copper in Pediatric Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A15943 | 28641784 | Metabolism | Ultrasonographic fatty liver indicator detects mild steatosis and correlates with metabolic/histological parameters in various liver diseases. | 2017 | Details |
| A15944 | 28641782 | Metabolism | High prevalence of apolipoprotein B dyslipoproteinemias in non-alcoholic fatty liver disease: The lifelines cohort study. | 2017 | Details |
| A15946 | 28641031 | Expert Opin Drug Saf | Treatment options for nonalcoholic steatohepatitis - a safety evaluation. | 2017 | Details |
| A15959 | 28637104 | Korean J Gastroenterol | [Treatment Options in Non-alcoholic Fatty Liver Disease]. | 2017 | Details |
| A15961 | 28637102 | Korean J Gastroenterol | [The Progression of Liver Fibrosis in Non-alcoholic Fatty Liver Disease]. | 2017 | Details |
| A15966 | 28635324 | Antioxid Redox Signal | Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis. | 2017 | Details |
| A15981 | 28628039 | J Clin Invest | ChREBP refines the hepatic response to fructose to protect the liver from injury. | 2017 | Details |
| A15982 | 28628033 | J Clin Invest | Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. | 2017 | Details |
| A15986 | 28626169 | Intern Med | New Discriminant Method for Identifying the Aggressive Disease Phenotype of Non-alcoholic Fatty Liver Disease. | 2017 | Details |
| A15990 | 28623272 | Sci Rep | Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells. | 2017 | Details |
| A15991 | 28623125 | Biochem Biophys Res Commun | Chronic intermittent hypoxia induces liver fibrosis in mice with diet-induced obesity via TLR4/MyD88/MAPK/NF-kB signaling pathways. | 2017 | Details |
| A16003 | 28618039 | J Gastroenterol Hepatol | Correlation between serum galectin-9 levels and liver fibrosis. | 2018 | Details |
| A16006 | 28615649 | Sci Rep | Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis. | 2017 | Details |
| A16008 | 28612749 | Ann Hepatol | Liver Biopsy in Chronic Liver Diseases: Is There a Favorable Benefit: Risk Balance? | 2018 | Details |
| A16010 | 28612550 | Sichuan Da Xue Xue Bao Yi Xue Ban | [Serum Wnt5a and Its Associations with Liver Steatosis and Fibrosis in Overweight and Obese People]. | 2017 | Details |
| A16013 | 28611510 | World J Gastroenterol | Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives. | 2017 | Details |
| A16015 | 28611297 | Oncotarget | Endogenous IL-33 has no effect on the progression of fibrosis during experimental steatohepatitis. | 2017 | Details |
| A16016 | 28611274 | Ann Hepatol | Meta-Analysis of Randomized Controlled Trials of Pharmacologic Agents in Non-alcoholic Steatohepatitis. | 2018 | Details |
| A16019 | 28608557 | J Food Sci | Salicornia Extract Ameliorates Salt-Induced Aggravation of Nonalcoholic Fatty Liver Disease in Obese Mice Fed a High-Fat Diet. | 2017 | Details |
| A16021 | 28606575 | Nutrition | Good adherence to the Mediterranean diet reduces the risk for NASH and diabetes in pediatric patients with obesity: The results of an Italian Study. | 2017 | Details |
| A16025 | 28604704 | Nat Med | Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling. | 2017 | Details |
| A16030 | 28600319 | Physiol Genomics | Microbiome and NAFLD: potential influence of aerobic fitness and lifestyle modification. | 2017 | Details |
| A16031 | 28600126 | Exp Mol Pathol | Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men. | 2017 | Details |
| A16032 | 28600116 | Surg Obes Relat Dis | Features of nonalcoholic steatohepatitis in severely obese children and adolescents undergoing sleeve gastrectomy. | 2017 | Details |
| A16041 | 28596677 | World J Gastroenterol | Relationship between adipose tissue dysfunction, vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease. | 2017 | Details |
| A16042 | 28596431 | Eur Respir J | Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease. | 2017 | Details |
| A16048 | 28594920 | PLoS One | Genetic polymorphisms associated with fatty liver disease and fibrosis in HIV positive patients receiving combined antiretroviral therapy (cART). | 2017 | Details |
| A16049 | 28594915 | PLoS One | Conophylline inhibits non-alcoholic steatohepatitis in mice. | 2017 | Details |
| A16050 | 28593786 | Rev Esp Enferm Dig | Characterization of liver changes in ZSF1 rats, an animal model of metabolic syndrome. | 2017 | Details |
| A16051 | 28593739 | Hepatol Res | Systematic review and meta-analysis to determine the impact of iron depletion in dysmetabolic iron overload syndrome and non-alcoholic fatty liver disease. | 2017 | Details |
| A16053 | 28593184 | Cell Mol Gastroenterol Hepatol | Epigenetics and Liver Fibrosis. | 2017 | Details |
| A16055 | 28591717 | Oncotarget | Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet. | 2017 | Details |
| A16060 | 28589339 | J Gastroenterol | A simple scoring system using type IV collagen 7S and aspartate aminotransferase for diagnosing nonalcoholic steatohepatitis and related fibrosis. | 2017 | Details |
| A16061 | 28587303 | Children (Basel) | The Role of Lipid and Lipoprotein Metabolism in Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16066 | 28586195 | ACS Chem Biol | Ex Vivo Cell-Based Screening Platform for Modulators of Hepatosteatosis. | 2017 | Details |
| A16067 | 28586172 | Hepatology | Comparison of laboratory tests, ultrasound, or magnetic resonance elastography to detect fibrosis in patients with nonalcoholic fatty liver disease: A meta-analysis. | 2017 | Details |
| A16068 | 28586157 | J Ultrasound Med | Role of Point Shear Wave Elastography in the Determination of the Severity of Fibrosis in Pediatric Liver Diseases With Pathologic Correlations. | 2017 | Details |
| A16085 | 28578014 | Free Radic Biol Med | Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway. | 2017 | Details |
| A16095 | 28573069 | World J Gastrointest Pathophysiol | Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. | 2017 | Details |
| A16097 | 28573066 | World J Gastrointest Pathophysiol | Embrionary way to create a fatty liver in portal hypertension. | 2017 | Details |
| A16098 | 28573064 | World J Gastrointest Pathophysiol | Nonalcoholic fatty liver disease: Diagnostic biomarkers. | 2017 | Details |
| A16099 | 28572039 | Dig Liver Dis | AST to Platelet Ratio Index and fibrosis 4 calculator scores for non-invasive assessment of hepatic fibrosis in patients with non-alcoholic fatty liver disease. | 2017 | Details |
| A16100 | 28571771 | Food Chem Toxicol | The lemon balm extract ALS-L1023 inhibits obesity and nonalcoholic fatty liver disease in female ovariectomized mice. | 2017 | Details |
| A16105 | 28570343 | Eur J Gastroenterol Hepatol | Controlled attenuation parameter for diagnosing steatosis in bariatric surgery candidates with suspected nonalcoholic fatty liver disease. | 2017 | Details |
| A16109 | 28565851 | Exp Ther Med | Pharmacological management of non-alcoholic fatty liver disease: Atorvastatin versus pentoxifylline. | 2017 | Details |
| A16110 | 28562737 | Sao Paulo Med J | Nonalcoholic fatty liver disease and bariatric surgery: a comprehensive review. | 2017 | Details |
| A16118 | 28555633 | Am J Gastroenterol | Low Birthweight Increases the Likelihood of Severe Steatosis in Pediatric Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16120 | 28554682 | Clin Gastroenterol Hepatol | Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver Disease, and Association With Visceral Obesity. | 2017 | Details |
| A16121 | 28552096 | Dan Med J | The role of incretin hormones and glucagon in patients with liver disease. | 2017 | Details |
| A16126 | 28550272 | J Biomed Res | Non-alcoholic fatty liver disease--a chronic disease of the 21<sup>st</sup> century. | 2018 | Details |
| A16127 | 28549912 | Exp Cell Res | Fatty liver and FGF21 physiology. | 2017 | Details |
| A16130 | 28547778 | FEBS Lett | Deletion of HNF1α in hepatocytes results in fatty liver-related hepatocellular carcinoma in mice. | 2017 | Details |
| A16131 | 28546081 | Pharmacol Ther | Targeting nuclear receptors for the treatment of fatty liver disease. | 2017 | Details |
| A16132 | 28545937 | J Hepatol | Treatment of NAFLD with diet, physical activity and exercise. | 2017 | Details |
| A16135 | 28544769 | Liver Int | Serum biomarkers can predict a change in liver fibrosis 1 year after lifestyle intervention for biopsy-proven NASH. | 2017 | Details |
| A16138 | 28544245 | Diabetes Obes Metab | Ghrelin receptor inverse agonists as a novel therapeutic approach against obesity-related metabolic disease. | 2017 | Details |
| A16139 | 28544208 | Liver Int | Ultra-high-field magnetic resonance spectroscopy in non-alcoholic fatty liver disease: Novel mechanistic and diagnostic insights of energy metabolism in non-alcoholic steatohepatitis and advanced fibrosis. | 2017 | Details |
| A16143 | 28540988 | Yonsei Med J | Pathologic Impact of Insulin Resistance and Sensitivity on the Severity of Liver Histopathology in Pediatric Non-Alcoholic Steatohepatitis. | 2017 | Details |
| A16148 | 28538192 | Biomed Pharmacother | Hepatic anti-inflammatory effect of hexane extracts of Dioscorea batatas Decne: Possible suppression of toll-like receptor 4-mediated signaling. | 2017 | Details |
| A16152 | 28536120 | FASEB J | Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor. | 2017 | Details |
| A16153 | 28535787 | BMC Infect Dis | Novel serum biomarkers modified by the body mass index z-score for the detection of liver fibrosis and steatosis in children with chronic hepatitis C. | 2017 | Details |
| A16158 | 28533304 | J Lipid Res | Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids. | 2017 | Details |
| A16161 | 28529818 | J Diabetes Metab | High protein/fish oil diet prevents hepatic steatosis in NONcNZO10 mice; association with diet/genetics-regulated micro-RNAs. | 2016 | Details |
| A16166 | 28527877 | Pharmacol Rep | Esculetin ameliorates hepatic fibrosis in high fat diet induced non-alcoholic fatty liver disease by regulation of FoxO1 mediated pathway. | 2017 | Details |
| A16168 | 28526997 | Adv Ther | NAFLD as a Sexual Dimorphic Disease: Role of Gender and Reproductive Status in the Development and Progression of Nonalcoholic Fatty Liver Disease and Inherent Cardiovascular Risk. | 2017 | Details |
| A16170 | 28526812 | Oncotarget | Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis. | 2017 | Details |
| A16173 | 28523578 | Dig Dis Sci | Prevalence and Predictors of Significant Fibrosis Among Subjects with Transient Elastography-Defined Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16175 | 28521870 | Metabolism | The use of statins alone, or in combination with pioglitazone and other drugs, for the treatment of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and related cardiovascular risk. An Expert Panel Statement. | 2017 | Details |
| A16176 | 28521774 | J Transl Med | Correlation of cell-free DNA plasma concentration with severity of non-alcoholic fatty liver disease. | 2017 | Details |
| A16177 | 28521680 | Curr Med Chem | Fatty Acids and Effects on In Vitro and In Vivo Models of Liver Steatosis. | 2019 | Details |
| A16178 | 28520503 | Metab Syndr Relat Disord | Serum Alanine Aminotransferase Trends and Their Relationship with Obesity and Metabolic Syndrome in United States Adolescents, 1999-2014. | 2017 | Details |
| A16179 | 28518142 | Cell Death Dis | MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2. | 2017 | Details |
| A16181 | 28515357 | JCI Insight | E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver. | 2017 | Details |
| A16200 | 28507930 | J Clin Transl Hepatol | Non-alcoholic Fatty Liver Disease in South Asians: A Review of the Literature. | 2017 | Details |
| A16204 | 28507343 | Sci Rep | Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice. | 2017 | Details |
| A16206 | 28506907 | J Hepatol | Validity criteria for the diagnosis of fatty liver by M probe-based controlled attenuation parameter. | 2017 | Details |
| A16207 | 28506744 | Adv Drug Deliv Rev | Hepatic stellate cells as key target in liver fibrosis. | 2017 | Details |
| A16209 | 28506362 | Gastroenterol Clin North Am | Current Concepts in Pediatric Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16222 | 28502444 | Pediatr Clin North Am | Nonalcoholic Fatty Liver Disease in Children: Hepatic and Extrahepatic Complications. | 2017 | Details |
| A16224 | 28501537 | Clin Gastroenterol Hepatol | Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers. | 2017 | Details |
| A16229 | 28497760 | Lancet Gastroenterol Hepatol | The intestinal microbiome and paediatric liver disease. | 2017 | Details |
| A16230 | 28497593 | J Gastroenterol Hepatol | Polymorphism of receptor-type tyrosine-protein phosphatase delta gene in the development of non-alcoholic fatty liver disease. | 2018 | Details |
| A16233 | 28494548 | Zhonghua Gan Zang Bing Za Zhi | [The role of cytochrome P450 in nonalcoholic fatty liver induced by high-fat diet: a gene expression profile analysis]. | 2017 | Details |
| A16234 | 28494529 | Clin Mol Hepatol | NASH Therapy: omega 3 supplementation, vitamin E, insulin sensitizers and statin drugs. | 2017 | Details |
| A16235 | 28493399 | Echocardiography | Diagnosis of fatty liver by computed tomography coronary artery calcium score. | 2017 | Details |
| A16236 | 28493388 | Hepatology | Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease. | 2017 | Details |
| A16240 | 28489307 | Liver Int | Non-alcoholic fatty liver and advanced fibrosis in the elderly: Results from a community-based Polish survey. | 2017 | Details |