Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24655 | 25755424 | J Clin Exp Hepatol | Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis. | 2012 | Details |
| A24658 | 25755421 | J Clin Exp Hepatol | Non-alcoholic Fatty Liver Disease: East Versus West. | 2012 | Details |
| A24666 | 22634121 | J Hepatol | D-livering the message: the importance of vitamin D status in chronic liver disease. | 2012 | Details |
| A24669 | 22628617 | J Lipid Res | Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis. | 2012 | Details |
| A24673 | 22619360 | Endocrinology | Endoplasmic reticulum stress induces the expression of fetuin-A to develop insulin resistance. | 2012 | Details |
| A24674 | 22617751 | Curr Opin Lipidol | Nonalcoholic fatty liver disease and lipids. | 2012 | Details |
| A24675 | 22617564 | Curr Opin Clin Nutr Metab Care | Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease. | 2012 | Details |
| A24676 | 22617561 | Curr Opin Clin Nutr Metab Care | DNA methylation and hepatic insulin resistance and steatosis. | 2012 | Details |
| A24677 | 22616493 | Acta Gastroenterol Latinoam | IGF-1 levels in different stages of liver steatosis and its association with metabolic syndrome. | 2012 | Details |
| A24686 | 22610002 | Clin Gastroenterol Hepatol | Prevalence and indicators of portal hypertension in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24688 | 22609053 | Trends Endocrinol Metab | Role of ceramides in nonalcoholic fatty liver disease. | 2012 | Details |
| A24690 | 22596186 | Curr Opin Cardiol | Nonalcoholic fatty liver disease and vascular risk. | 2012 | Details |
| A24703 | 22582214 | J Appl Physiol (1985) | Short-term exercise reduces markers of hepatocyte apoptosis in nonalcoholic fatty liver disease. | 2012 | Details |
| A24704 | 22579612 | Mol Cell Endocrinol | The role of angiotensin II in nonalcoholic steatohepatitis. | 2012 | Details |
| A24705 | 22577564 | Int J Hepatol | Role of NKT Cells in the Pathogenesis of NAFLD. | 2012 | Details |
| A24707 | 22576780 | Diabetes Metab Res Rev | Diabetic fatty liver disease is associated with specific changes in blood-borne markers. | 2012 | Details |
| A24712 | 22570745 | Gut Liver | NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications. | 2012 | Details |
| A24713 | 22570680 | Therap Adv Gastroenterol | Secondary causes of nonalcoholic fatty liver disease. | 2012 | Details |
| A24714 | 22569763 | J Gastroenterol | Increased serum liver X receptor ligand oxysterols in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24718 | 22567185 | World J Hepatol | G6PT-H6PDH-11βHSD1 triad in the liver and its implication in the pathomechanism of the metabolic syndrome. | 2012 | Details |
| A24719 | 22565095 | Nat Rev Gastroenterol Hepatol | Increased risk of cardiovascular disease and chronic kidney disease in NAFLD. | 2012 | Details |
| A24722 | 22561686 | Nat Med | Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration. | 2012 | Details |
| A24724 | 22560210 | Cell Metab | Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance. | 2012 | Details |
| A24732 | 22551412 | J Med Food | Raspberry ketone protects rats fed high-fat diets against nonalcoholic steatohepatitis. | 2012 | Details |
| A24735 | 22546916 | Comp Med | Effects of increased dietary cholesterol with carbohydrate restriction on hepatic lipid metabolism in Guinea pigs. | 2012 | Details |
| A24736 | 22546860 | J Clin Invest | The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. | 2012 | Details |
| A24742 | 22545359 | Pak J Biol Sci | Non alcoholic fatty liver disease, insulin resistance, dyslipidemia and atherogenic ratios in epileptic children and adolescents on long term antiepileptic drug therapy. | 2012 | Details |
| A24747 | 22541252 | Gastroenterol Hepatol | [Influence of non-alcoholic fatty liver disease on cardiovascular disease]. | 2012 | Details |
| A24749 | 22539458 | Diabetes Metab Res Rev | Hepatic lipase activity is increased in non-alcoholic fatty liver disease beyond insulin resistance. | 2012 | Details |
| A24757 | 22532269 | Hepatology | Relationship between adipose tissue insulin resistance and liver histology in nonalcoholic steatohepatitis: a pioglitazone versus vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis trial follow-up study. | 2012 | Details |
| A24758 | 22531980 | Hepatology | Retinoids ameliorate insulin resistance in a leptin-dependent manner in mice. | 2012 | Details |
| A24760 | 22530350 | Eur Rev Med Pharmacol Sci | Lys656Asn polymorphism of leptin receptor, leptin levels and insulin resistance in patients with non alcoholic fatty liver disease. | 2012 | Details |
| A24764 | 22525431 | Lab Invest | Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function. | 2012 | Details |
| A24766 | 22521558 | Clin Res Hepatol Gastroenterol | Non-alcoholic fatty liver disease in children. | 2012 | Details |
| A24772 | 22519397 | Curr Med Chem | Mechanisms involved in the protective effects of metformin against nonalcoholic fatty liver disease. | 2012 | Details |
| A24774 | 22509248 | PLoS One | Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD. | 2012 | Details |
| A24780 | 22505276 | Hepatology | Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: new evidence on the potential therapeutic mechanism. | 2012 | Details |
| A24781 | 22505194 | Hepatology | Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis. | 2012 | Details |
| A24784 | 22500386 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Clinical study of Qinggan Huatan Huoxue Recipe on the treatment of non-alcoholic steatohepatitis]. | 2012 | Details |
| A24785 | 22498245 | Best Pract Res Clin Endocrinol Metab | Metabolic insights from extreme human insulin resistance phenotypes. | 2012 | Details |
| A24786 | 22496902 | PLoS One | Effect of dietary advanced glycation end products on mouse liver. | 2012 | Details |
| A24787 | 22495402 | Eur J Gastroenterol Hepatol | Relation of epicardial adipose tissue and carotid intima-media thickness in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24798 | 22481454 | Ann Hepatol | High coffee intake is associated with lower grade nonalcoholic fatty liver disease: the role of peripheral antioxidant activity. | 2012 | Details |
| A24802 | 22476041 | J Clin Gastroenterol | Obesity-independent association of human adenovirus Ad37 seropositivity with nonalcoholic fatty liver disease. | 2012 | Details |
| A24804 | 22474039 | Diabetes Care | Multiorgan insulin sensitivity in lean and obese subjects. | 2012 | Details |
| A24813 | 22468076 | World J Gastroenterol | Genetically modified mouse models for the study of nonalcoholic fatty liver disease. | 2012 | Details |
| A24814 | 22468051 | Indian J Clin Biochem | Role of cytokines in the pathogenesis of non-alcoholic Fatty liver disease. | 2011 | Details |
| A24817 | 22467327 | J Clin Lab Anal | Visfatin levels in nonalcoholic fatty liver disease. | 2012 | Details |
| A24818 | 22467277 | Hepatology | Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease. | 2012 | Details |
| A24824 | 22464551 | Nutrition | Non-alcoholic fatty liver disease in children now: lifestyle changes and pharmacologic treatments. | 2012 | Details |
| A24827 | 22458550 | Nutr Metab (Lond) | Black rice (Oryza sativa L.) extract attenuates hepatic steatosis in C57BL/6 J mice fed a high-fat diet via fatty acid oxidation. | 2012 | Details |
| A24829 | 22457136 | Chin J Integr Med | Ping-tang Recipe () improves insulin resistance and attenuates hepatic steatosis in high-fat diet-induced obese rats. | 2012 | Details |
| A24832 | 22450341 | Hormones (Athens) | Adiponectin: regulation of its production and its role in human diseases. | 2012 | Details |
| A24837 | 22442265 | J Clin Endocrinol Metab | Intrahepatic insulin exposure, intrahepatocellular lipid and regional body fat in nonalcoholic fatty liver disease. | 2012 | Details |
| A24838 | 22441997 | Zentralbl Chir | [NASH (non-alcoholic steatohepatitis): fatty liver or fatal liver disease?]. | 2012 | Details |
| A24840 | 22438225 | J Clin Endocrinol Metab | Fibroblast growth factor 21 (FGF-21) and its relation to obesity, metabolic syndrome, and nonalcoholic fatty liver in children: a longitudinal analysis. | 2012 | Details |
| A24841 | 22438219 | Obes Surg | Laparoscopic sleeve gastrectomy as a stand-alone procedure for morbid obesity: report of 1,000 cases and 3-year follow-up. | 2012 | Details |
| A24845 | 22434759 | Pediatr Obes | Energy expenditure and insulin sensitivity evaluation in obese children affected by hepatosteatosis. | 2012 | Details |
| A24847 | 22434756 | Pediatr Obes | Influence of elevated liver fat on circulating adipocytokines and insulin resistance in obese Hispanic adolescents. | 2012 | Details |
| A24864 | 22420611 | Clin Sci (Lond) | Beneficial effects of rosuvastatin on insulin resistance, adiposity, inflammatory markers and non-alcoholic fatty liver disease in mice fed on a high-fat diet. | 2012 | Details |
| A24871 | 22418886 | Semin Liver Dis | Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil. | 2012 | Details |
| A24873 | 22418884 | Semin Liver Dis | NAFLD in the absence of metabolic syndrome: different epidemiology, pathogenetic mechanisms, risk factors for disease progression? | 2012 | Details |
| A24879 | 22408036 | Eur Heart J | Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor? | 2012 | Details |
| A24883 | 22397032 | Adv Clin Chem | Fetuin-A and the cardiovascular system. | 2012 | Details |
| A24886 | 22395062 | J Clin Gastroenterol | Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease. | 2012 | Details |
| A24887 | 22394502 | J Lipid Res | Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. | 2012 | Details |
| A24888 | 22394108 | Metab Syndr Relat Disord | Nonalcoholic fatty liver disease: a nutritional approach. | 2012 | Details |
| A24889 | 22391060 | Proc Nutr Soc | Potential health benefits of moderate alcohol consumption: current perspectives in research. | 2012 | Details |
| A24892 | 22386931 | Metabolism | Serum ferritin levels predict incident non-alcoholic fatty liver disease in healthy Korean men. | 2012 | Details |
| A24894 | 22385956 | Cell | Mechanisms for insulin resistance: common threads and missing links. | 2012 | Details |
| A24898 | 22382613 | Minerva Endocrinol | Neuroendocrine and endocrine dysfunction in the hyperinsulinemic PCOS patient: the role of metformin. | 2012 | Details |
| A24904 | 22375522 | Expert Rev Gastroenterol Hepatol | Nonalcoholic fatty liver disease and bariatric surgery. | 2012 | Details |
| A24906 | 22374640 | Diabetes Care | Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
| A24910 | 22372457 | Histopathology | The epidemiology, pathogenesis and histopathology of fatty liver disease. | 2012 | Details |
| A24917 | 22363403 | PLoS One | A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease. | 2012 | Details |
| A24919 | 22360487 | Curr Med Chem | Non-alcoholic steatohepatitis: what can we learn from animal models? | 2012 | Details |
| A24922 | 22359625 | PLoS One | Liver and muscle in morbid obesity: the interplay of fatty liver and insulin resistance. | 2012 | Details |
| A24927 | 22348916 | Drugs Today (Barc) | Current therapies for nonalcoholic fatty liver disease. | 2011 | Details |
| A24928 | 22348670 | Ugeskr Laeger | [Prognosis and treatment of non-alcoholic fatty liver disease and steatohepatitis]. | 2012 | Details |
| A24933 | 22343419 | Free Radic Biol Med | Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. | 2012 | Details |
| A24944 | 22320918 | J Gastroenterol Hepatol | Pathophysiology guided treatment of nonalcoholic steatohepatitis. | 2012 | Details |
| A24949 | 22326764 | Clin Res Hepatol Gastroenterol | HCC and NASH: how strong is the clinical demonstration? | 2012 | Details |
| A24950 | 22326465 | J Hepatol | Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. | 2012 | Details |
| A24951 | 22326434 | Gastroenterology | Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. | 2012 | Details |
| A24960 | 22310735 | J Gastroenterol | Inflammation and fibrogenesis in steatohepatitis. | 2012 | Details |
| A24964 | 22307032 | Gastroenterology | Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice. | 2012 | Details |
| A24972 | 22294100 | Cell Mol Life Sci | A role for sphingolipids in the pathophysiology of obesity-induced inflammation. | 2012 | Details |
| A24984 | 22278337 | Diabetologia | Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials. | 2012 | Details |
| A24987 | 22275361 | J Biol Chem | Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. | 2012 | Details |
| A24994 | 22269154 | Gene | Association of adiponectin gene functional polymorphisms (-11377C/G and +45T/G) with nonalcoholic fatty liver disease. | 2011 | Details |
| A24995 | 22268100 | Am J Physiol Gastrointest Liver Physiol | Consumption of a high-fat diet rapidly exacerbates the development of fatty liver disease that occurs with chronically elevated glucocorticoids. | 2012 | Details |
| A24997 | 22265683 | Dig Liver Dis | Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property. | 2012 | Details |
| A25008 | 22249092 | Saudi J Gastroenterol | The association of metabolic syndrome, insulin resistance and non-alcoholic fatty liver disease in overweight/obese children. | 2012 | Details |
| A25011 | 22237875 | JPEN J Parenter Enteral Nutr | Nonalcoholic fatty liver disease in pediatric patients. | 2012 | Details |
| A25017 | 22245895 | J Hepatol | Predictors for incidence and remission of NAFLD in the general population during a seven-year prospective follow-up. | 2012 | Details |
| A25018 | 22242926 | Metab Syndr Relat Disord | Docosahexaenoic acid prevents trans-10, cis-12-conjugated linoleic acid-induced nonalcoholic fatty liver disease in mice by altering expression of hepatic genes regulating fatty acid synthesis and oxidation. | 2012 | Details |
| A25023 | 22239625 | Curr Vasc Pharmacol | Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options. | 2012 | Details |
| A25025 | 22238690 | PLoS One | Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver. | 2012 | Details |
| A25026 | 22236001 | Clin Exp Immunol | Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells. | 2012 | Details |
| A25030 | 22229957 | Int J Food Sci Nutr | Serum vitamin B12 and folate levels in patients with non-alcoholic fatty liver disease. | 2012 | Details |