Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A17084 | 27999641 | Caspian J Intern Med | Assessment of transient elastography (FibroScan) for diagnosis of fibrosis in non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2016 | Details |
A17087 | 27998724 | Am J Pathol | Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis. | 2016 | Details |
A17092 | 27996033 | Sci Rep | The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy. | 2016 | Details |
A17098 | 27993651 | Biochim Biophys Acta Mol Cell Biol Lipids | NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. | 2016 | Details |
A17099 | 27992443 | PLoS One | Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD. | 2016 | Details |
A17110 | 27986627 | Eur J Pharmacol | A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models. | 2016 | Details |
A17111 | 27986466 | Trends Endocrinol Metab | Mitochondrial Adaptation in Nonalcoholic Fatty Liver Disease: Novel Mechanisms and Treatment Strategies. | 2016 | Details |
A17116 | 27984176 | J Hepatol | PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis. | 2016 | Details |
A17117 | 27982761 | Radiology | Liver Stiffness in Pediatric Patients with Fatty Liver Disease: Diagnostic Accuracy and Reproducibility of Shear-Wave Elastography. | 2016 | Details |
A17120 | 27981809 | Mol Nutr Food Res | Chicoric acid attenuate a nonalcoholic steatohepatitis by inhibiting key regulators of lipid metabolism, fibrosis, oxidation, and inflammation in mice with methionine and choline deficiency. | 2017 | Details |
A17121 | 27981615 | Hepatology | Metabolic and histological implications of intrahepatic triglyceride content in nonalcoholic fatty liver disease. | 2017 | Details |
A17127 | 27977757 | PLoS One | Docosahexanoic Acid Plus Vitamin D Treatment Improves Features of NAFLD in Children with Serum Vitamin D Deficiency: Results from a Single Centre Trial. | 2016 | Details |
A17137 | 27967209 | Antioxid Redox Signal | Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway. | 2017 | Details |
A17139 | 27966386 | Hematology | More on the thrombocytopenia of the non-alcoholic fatty liver disease. | 2016 | Details |
A17150 | 27956809 | World J Gastroenterol | Disease-specific miR-34a as diagnostic marker of non-alcoholic steatohepatitis in a Chinese population. | 2016 | Details |
A17151 | 27956794 | World J Gastroenterol | Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis. | 2016 | Details |
A17152 | 27956792 | World J Gastroenterol | Fatty liver is associated with an increased risk of diabetes and cardiovascular disease - Evidence from three different disease models: NAFLD, HCV and HIV. | 2016 | Details |
A17159 | 27941355 | Curr Opin Infect Dis | Managing nonalcoholic fatty liver disease in patients living with HIV. | 2017 | Details |
A17160 | 27939923 | Dig Liver Dis | CD98 siRNA-loaded nanoparticles decrease hepatic steatosis in mice. | 2016 | Details |
A17164 | 27938560 | Zhonghua Gan Zang Bing Za Zhi | [Effect of targeted inhibition of hypoxia-inducible factor-1α by 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole on the progression of non-alcoholic fatty liver disease in rats]. | 2016 | Details |
A17165 | 27937040 | Expert Rev Gastroenterol Hepatol | Multiparametric or practical quantitative liver MRI: towards millisecond, fat fraction, kilopascal and function era. | 2016 | Details |
A17166 | 27936481 | Z Gastroenterol | Patients with ultrasound diagnosis of hepatic steatosis are at high metabolic risk. | 2016 | Details |
A17167 | 27936280 | J Gastroenterol Hepatol | Application of the combined FibroMeter vibration-controlled transient elastography algorithm in Chinese patients with non-alcoholic fatty liver disease. | 2017 | Details |
A17169 | 27936091 | PLoS One | Development of Serum Marker Models to Increase Diagnostic Accuracy of Advanced Fibrosis in Nonalcoholic Fatty Liver Disease: The New LINKI Algorithm Compared with Established Algorithms. | 2016 | Details |
A17172 | 27935134 | Cell Biochem Funct | Strain- and time-dependent alterations in hepatic iron metabolism in a murine model of nonalcoholic steatohepatitis. | 2016 | Details |
A17175 | 27930988 | Biomed Pharmacother | Potential involvement of PPAR α activation in diminishing the hepatoprotective effect of fenofibrate in NAFLD: Accuracy of non- invasive panel in determining the stage of liver fibrosis in rats. | 2016 | Details |
A17184 | 27923447 | Metabolism | Amelioration of non-alcoholic fatty liver disease with NPC1L1-targeted IgY or n-3 polyunsaturated fatty acids in mice. | 2016 | Details |
A17185 | 27923446 | Metabolism | Obesity is more closely related with hepatic steatosis and fibrosis measured by transient elastography than metabolic health status. | 2016 | Details |
A17186 | 27922486 | Eur J Gastroenterol Hepatol | The post-transplant course of patients undergoing liver transplantation for nonalcoholic steatohepatitis versus cryptogenic cirrhosis: a retrospective case-control study. | 2017 | Details |
A17189 | 27920819 | Res Pharm Sci | Co-administration of metformin and N-acetylcysteine with dietary control improves the biochemical and histological manifestations in rats with non-alcoholic fatty liver. | 2016 | Details |
A17190 | 27920470 | World J Gastroenterol | Nonalcoholic fatty liver disease - A multisystem disease? | 2016 | Details |
A17202 | 27916647 | Biochimie | PPARs and nonalcoholic fatty liver disease. | 2016 | Details |
A17210 | 27913210 | Free Radic Biol Med | TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. | 2016 | Details |
A17212 | 27911262 | Gastroenterology | Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease. | 2016 | Details |
A17218 | 27908400 | J Trace Elem Med Biol | Low hepatic copper content and PNPLA3 polymorphism in non-alcoholic fatty liver disease in patients without metabolic syndrome. | 2016 | Details |
A17225 | 27903831 | J Nutr | Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease. | 2016 | Details |
A17226 | 27903585 | Am J Physiol Cell Physiol | Autophagy in chronic liver diseases: the two faces of Janus. | 2016 | Details |
A17237 | 27895397 | World J Gastroenterol | Th17 involvement in nonalcoholic fatty liver disease progression to non-alcoholic steatohepatitis. | 2016 | Details |
A17238 | 27895393 | World J Gastroenterol | Emerging role of obeticholic acid in the management of nonalcoholic fatty liver disease. | 2016 | Details |
A17248 | 27889947 | Hepatol Res | Pathological Findings of NASH and NAFLD: for Guidebook of NASH and NAFLD, 2015: The Japan Society of Hepatology. | 2017 | Details |
A17254 | 27889556 | Int Immunopharmacol | Compact bone-derived mesenchymal stem cells attenuate nonalcoholic steatohepatitis in a mouse model by modulation of CD4 cells differentiation. | 2016 | Details |
A17255 | 27889327 | Mol Aspects Med | Epigenetics in non-alcoholic fatty liver disease. | 2016 | Details |
A17256 | 27889186 | Cancer Cell | Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis. | 2016 | Details |
A17261 | 27881858 | Int J Obes (Lond) | Safety and efficacy of bariatric surgery in patients with advanced fibrosis. | 2016 | Details |
A17265 | 27880977 | Hepatology | Bariatric surgery for nonalcoholic steatohepatitis: A clinical and cost-effectiveness analysis. | 2017 | Details |
A17272 | 27872651 | Evid Based Complement Alternat Med | A Review of Western and Traditional Chinese Medical Approaches to Managing Nonalcoholic Fatty Liver Disease. | 2016 | Details |
A17275 | 27869416 | Arch Argent Pediatr | Non-alcoholic fatty liver disease: a new epidemic in children. | 2016 | Details |
A17282 | 27863346 | J Nutr Biochem | A diet-induced Sprague-Dawley rat model of nonalcoholic steatohepatitis-related cirrhosis. | 2016 | Details |
A17287 | 27862719 | Hepatol Res | Development of hepatocellular carcinoma in Japanese patients with biopsy-proven non-alcoholic fatty liver disease: Association between PNPLA3 genotype and hepatocarcinogenesis/fibrosis progression. | 2016 | Details |
A17288 | 27862590 | J Magn Reson Imaging | Hepatic gadoxetic acid uptake as a measure of diffuse liver disease: Where are we? | 2016 | Details |
A17290 | 27862096 | Aliment Pharmacol Ther | Improvement in liver histology due to lifestyle modification is independently associated with improved kidney function in patients with non-alcoholic steatohepatitis. | 2016 | Details |
A17296 | 27859583 | J Gastroenterol Hepatol | External validation of the non-alcoholic fatty liver disease fibrosis score for assessing advanced fibrosis in Korean patients. | 2017 | Details |
A17298 | 27859470 | Aliment Pharmacol Ther | Non-alcoholic fatty liver diseases and risk of colorectal neoplasia. | 2016 | Details |
A17312 | 27853271 | Sci Rep | Foetal programming by methyl donor deficiency produces steato-hepatitis in rats exposed to high fat diet. | 2016 | Details |
A17318 | 27851786 | PLoS One | Calcium Reduces Liver Injury in Mice on a High-Fat Diet: Alterations in Microbial and Bile Acid Profiles. | 2016 | Details |
A17331 | 27837778 | Gastroenterol Clin North Am | Nonalcoholic Fatty Liver Disease: Pathophysiology and Management. | 2016 | Details |
A17332 | 31435207 | J Taibah Univ Med Sci | The role of elevated alanine aminotransferase (ALT), FasL and atherogenic dyslipidemia in type II diabetes mellitus. | 2016 | Details |
A17333 | 27837387 | Obes Surg | Vitamin D3 Loading Is Superior to Conventional Supplementation After Weight Loss Surgery in Vitamin D-Deficient Morbidly Obese Patients: a Double-Blind Randomized Placebo-Controlled Trial. | 2017 | Details |
A17334 | 27836992 | J Lipid Res | Combined effects of the PNPLA3 rs738409, TM6SF2 rs58542926, and MBOAT7 rs641738 variants on NAFLD severity: a multicenter biopsy-based study. | 2016 | Details |
A17335 | 27836788 | Chem Biol Interact | Regression of fibrosis/cirrhosis by Glycine propionyl-l-carnitine treatment in d-Galactosamine induced chronic liver damage. | 2016 | Details |
A17340 | 27834813 | Biology (Basel) | The Potential of Non-Provitamin A Carotenoids for the Prevention and Treatment of Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
A17343 | 27833386 | World J Gastroenterol | Fibrosis in nonalcoholic fatty liver disease: Noninvasive assessment using computed tomography volumetry. | 2016 | Details |
A17351 | 27830836 | Sci Rep | Long-term lifestyle interventions in middle-aged and elderly men with nonalcoholic fatty liver disease: a randomized controlled trial. | 2016 | Details |
A17359 | 27824642 | Eur J Gastroenterol Hepatol | Coffee consumption and risk of nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2017 | Details |
A17368 | 27822476 | Biomed Res Int | Pathogenesis of Nonalcoholic Steatohepatitis: Interactions between Liver Parenchymal and Nonparenchymal Cells. | 2016 | Details |
A17372 | 27821715 | Physiol Rep | A novel diet-induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for nonalcoholic steatohepatitis. | 2016 | Details |
A17373 | 27821024 | Acta Gastroenterol Belg | Predictive value of neutrophiltolymphocyte ratio in the severity of non-alcoholic fatty liver disease among type 2 diabetes patients. | 2017 | Details |
A17382 | 27813192 | Clin Exp Pharmacol Physiol | Naltrexone changes the expression of lipid metabolism-related proteins in the endoplasmic reticulum stress induced hepatic steatosis in mice. | 2017 | Details |
A17386 | 27810989 | Diabetes Care | Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference. | 2016 | Details |
A17396 | 27644736 | Am J Gastroenterol | Vitamin D is Not Associated With Severity in NAFLD: Results of a Paired Clinical and Gene Expression Profile Analysis. | 2016 | Details |
A17409 | 27797398 | Eur J Clin Invest | Hepatic chemerin mRNA expression is reduced in human nonalcoholic steatohepatitis. | 2016 | Details |
A17410 | 27796814 | Endocrine | Low vitamin D status is associated with advanced liver fibrosis in patients with nonalcoholic fatty liver disease. | 2016 | Details |
A17412 | 27796056 | J Gastroenterol Hepatol | Systematic review: Current evidence in non-alcoholic fatty liver disease lacks relevance to patients with advanced fibrosis. | 2017 | Details |
A17413 | 27795938 | Curr Hepatol Rep | Noninvasive Markers of Fibrosis and Inflammation in Nonalcoholic Fatty Liver Disease. | 2016 | Details |
A17418 | 27794176 | Hepatol Res | High fasting insulin concentrations may be a pivotal predictor for the severity of hepatic fibrosis beyond the glycemic status in non-alcoholic fatty liver disease patients before development of diabetes mellitus. | 2016 | Details |
A17432 | 27710160 | Metab Syndr Relat Disord | Treatment of Nonalcoholic Fatty Liver Disease with Long-Chain n-3 Polyunsaturated Fatty Acids in Humans. | 2016 | Details |
A17434 | 27613872 | J Biol Chem | Targeting Liver Fibrosis with a Cell-penetrating Protease-activated Receptor-2 (PAR2) Pepducin. | 2016 | Details |
A17436 | 27569726 | Gastroenterology | In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores. | 2016 | Details |
A17437 | 27539017 | Hepatol Res | Liver stiffness measurement to platelet ratio index predicts the stage of liver fibrosis in non-alcoholic fatty liver disease. | 2016 | Details |
A17443 | 27743352 | Adv Ther | Evaluating the Relationship Between Metabolic Syndrome and Liver Biopsy-Proven Non-Alcoholic Steatohepatitis in China: A Multicenter Cross-Sectional Study Design. | 2016 | Details |
A17454 | 27603289 | AIDS | Nonalcoholic fatty liver disease diagnosed by transient elastography with controlled attenuation parameter in unselected HIV monoinfected patients. | 2016 | Details |
A17457 | 27778429 | Liver Int | Multiparametric magnetic resonance imaging for the assessment of non-alcoholic fatty liver disease severity. | 2017 | Details |
A17459 | 27778367 | Aliment Pharmacol Ther | Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis. | 2016 | Details |
A17461 | 27777925 | Can J Gastroenterol Hepatol | The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease. | 2016 | Details |
A17471 | 27773935 | Acta Pharmacol Sin | Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation. | 2016 | Details |
A17475 | 27699993 | Liver Int | Transient elastography for the diagnosis of liver fibrosis: a systematic review of economic evaluations. | 2016 | Details |
A17480 | 27522549 | Dig Liver Dis | Transient elastography in healthy subjects and factors influencing liver stiffness in non-alcoholic fatty liver disease: An Italian community-based population study. | 2016 | Details |
A17499 | 27543837 | Hepatology | The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe. | 2016 | Details |
A17501 | 27315352 | Hepatology | Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. | 2016 | Details |
A17502 | 27301788 | Hepatology | Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury. | 2016 | Details |
A17506 | 27098507 | Diabetes Metab J | Statins Increase Mitochondrial and Peroxisomal Fatty Acid Oxidation in the Liver and Prevent Non-Alcoholic Steatohepatitis in Mice. | 2016 | Details |
A17509 | 27764892 | Pediatr Obes | Association between plasminogen activator inhibitor-1 and severity of liver injury and cardiovascular risk in children with non-alcoholic fatty liver disease. | 2016 | Details |
A17511 | 27762491 | Pediatr Transplant | Resolution of non-alcoholic steatohepatitis after growth hormone replacement in a pediatric liver transplant patient with panhypopituitarism. | 2016 | Details |
A17519 | 27759627 | Medicine (Baltimore) | Thiazolidinediones for nonalcoholic steatohepatitis: A meta-analysis of randomized clinical trials. | 2016 | Details |
A17523 | 27757953 | J Pathol | Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances. | 2016 | Details |
A17526 | 27756518 | Nutr Metab Cardiovasc Dis | Intracellular and extracellular miRNome deregulation in cellular models of NAFLD or NASH: Clinical implications. | 2016 | Details |
A17528 | 27717115 | J Sci Food Agric | Pomegranate juice prevents development of non-alcoholic fatty liver disease in rats by attenuating oxidative stress and inflammation. | 2016 | Details |
A17536 | 27521509 | Clin Gastroenterol Hepatol | Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial. | 2016 | Details |
A17541 | 27753194 | Hepatol Res | Assessment of transient elastography in Japanese patients with non-alcoholic fatty liver disease. | 2016 | Details |
A17546 | 27577682 | J Pathol | Mitochondrial genome architecture in non-alcoholic fatty liver disease. | 2016 | Details |