Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02233 | 34450307 | Pharmacol Res | Traditional Chinese medicine in the treatment of nonalcoholic steatohepatitis. | 2021 | Details |
| A02237 | 34449768 | PLoS One | Association of IRS1 (Gly972Arg) and IRS2 (Gly1057Asp) genes polymorphisms with OSA and NAFLD in Asian Indians. | 2021 | Details |
| A02242 | 34448598 | Metab Syndr Relat Disord | Non-Alcoholic Steatohepatitis Severity Associates with FGF21 Level and Kidney Glucose Uptake. | 2021 | Details |
| A02247 | 34447378 | Front Immunol | Crosstalk Between Plasma Cytokines, Inflammation, and Liver Damage as a New Strategy to Monitoring NAFLD Progression. | 2021 | Details |
| A02248 | 34447235 | World J Gastroenterol | Advanced glycation end product: A potential biomarker for risk stratification of non-alcoholic fatty liver disease in ELSA-Brasil study. | 2021 | Details |
| A02250 | 34446275 | Maturitas | The interplay between metabolic dysregulations and non-alcoholic fatty liver disease in women after menopause. | 2021 | Details |
| A02251 | 34446271 | Clin Ther | Emerging and Established Therapeutic Approaches for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02252 | 34446090 | Diabetol Metab Syndr | Nonalcoholic fatty liver disease and the risk of insulin-requiring gestational diabetes. | 2021 | Details |
| A02253 | 34446002 | Lipids Health Dis | Sirtuin3 rs28365927 functional variant confers to the high risk of non-alcoholic fatty liver disease in Chinese Han population. | 2021 | Details |
| A02262 | 34444750 | Nutrients | Plasma Free Fatty Acid Concentration as a Modifiable Risk Factor for Metabolic Disease. | 2021 | Details |
| A02265 | 34443333 | Molecules | Phenolics-Rich Extracts of Dietary Plants as Regulators of Fructose Uptake in Caco-2 Cells via GLUT5 Involvement. | 2021 | Details |
| A02267 | 34441497 | Foods | Probiotics and Prebiotics as a Strategy for Non-Alcoholic Fatty Liver Disease, a Narrative Review. | 2021 | Details |
| A02268 | 34441028 | Medicina (Kaunas) | Phytotherapy as Multi-Hit Therapy to Confront the Multiple Pathophysiology in Non-Alcoholic Fatty Liver Disease: A Systematic Review of Experimental Interventions. | 2021 | Details |
| A02271 | 34440803 | Cells | NAFLD-Related Hepatocarcinoma: The Malignant Side of Metabolic Syndrome. | 2021 | Details |
| A02275 | 34440507 | Life (Basel) | Association of Nonalcoholic Hepatic Fibrosis with Body Composition in Female and Male Psoriasis Patients. | 2021 | Details |
| A02276 | 34440495 | Life (Basel) | Differences among Three Skeletal Muscle Mass Indices in Predicting Non-Alcoholic Fatty Liver Disease: Korean Nationwide Population-Based Study. | 2021 | Details |
| A02289 | 34435032 | ERJ Open Res | 1-year outcomes for lung transplantation recipients with non-alcoholic fatty liver disease. | 2021 | Details |
| A02290 | 34434943 | Front Med (Lausanne) | Role of Carnitine in Non-alcoholic Fatty Liver Disease and Other Related Diseases: An Update. | 2021 | Details |
| A02295 | 34433228 | Hepatology | Up-regulation of thioesterase superfamily member 2 in skeletal muscle promotes hepatic steatosis and insulin resistance in mice. | 2021 | Details |
| A02297 | 34432804 | PLoS One | Baseline homeostasis model assessment of insulin resistance associated with fibrosis progression in patients with nonalcoholic fatty liver disease without diabetes: A cohort study. | 2021 | Details |
| A02300 | 34431493 | J Clin Endocrinol Metab | LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in Obese Adults With Modest Hypertriglyceridemia. | 2022 | Details |
| A02306 | 34426744 | Evid Based Complement Alternat Med | Targeting miRNA by Natural Products: A Novel Therapeutic Approach for Nonalcoholic Fatty Liver. | 2021 | Details |
| A02307 | 34426178 | J Integr Med | Hepatic protective effects of Shenling Baizhu powder, a herbal compound, against inflammatory damage via TLR4/NLRP3 signalling pathway in rats with nonalcoholic fatty liver disease. | 2021 | Details |
| A02312 | 34423525 | Int J Clin Pract | Omega 3-rich Camelina sativa oil in the context of a weight loss program improves glucose homeostasis, inflammation and oxidative stress in patients with NAFLD: A randomised placebo-controlled clinical trial. | 2021 | Details |
| A02326 | 34417811 | Endocrinology | Rosiglitazone Requires Hepatocyte PPARγ Expression to Promote Steatosis in Male Mice With Diet-Induced Obesity. | 2021 | Details |
| A02342 | 34410623 | Hum Cell | Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression. | 2021 | Details |
| A02343 | 34410573 | Dig Dis Sci | A Review of the Epidemiology, Pathophysiology, and Efficacy of Anti-diabetic Drugs Used in the Treatment of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02347 | 34407600 | Diabetes Metab J | Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway. | 2021 | Details |
| A02348 | 34407548 | Exp Clin Endocrinol Diabetes | Hepatic Meteorin-like and Krüppel-like Factor 3 are Associated with Weight Loss and Liver Injury. | 2021 | Details |
| A02352 | 34406209 | Braz J Med Biol Res | α,β-Amyrin prevents steatosis and insulin resistance in a high-fat diet-induced mouse model of NAFLD via the AMPK-mTORC1-SREBP1 signaling mechanism. | 2021 | Details |
| A02353 | 34406004 | J Agric Food Chem | Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis. | 2021 | Details |
| A02362 | 34402795 | JMIR Form Res | Utilization of a Directly Supervised Telehealth-Based Exercise Training Program in Patients With Nonalcoholic Steatohepatitis: Feasibility Study. | 2021 | Details |
| A02365 | 34401690 | JHEP Rep | Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication. | 2021 | Details |
| A02367 | 34400897 | Int J Med Sci | Association of Hepatic Steatosis Index and Fatty Liver Index with Carotid Atherosclerosis in Type 2 Diabetes. | 2021 | Details |
| A02373 | 34399601 | Int J Immunopathol Pharmacol | Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice. | 2022 | Details |
| A02383 | 34395490 | Front Nutr | Broccoli Florets Supplementation Improves Insulin Sensitivity and Alters Gut Microbiome Population-A Steatosis Mice Model Induced by High-Fat Diet. | 2021 | Details |
| A02387 | 34393826 | Front Physiol | Similarities and Differences: A Comparative Review of the Molecular Mechanisms and Effectors of NAFLD and AFLD. | 2021 | Details |
| A02393 | 34390493 | Eur J Clin Invest | Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable diets. | 2021 | Details |
| A02398 | 34387409 | Diabetes Obes Metab | A clinical overview of non-alcoholic fatty liver disease: A guide to diagnosis, the clinical features, and complications-What the non-specialist needs to know. | 2021 | Details |
| A02399 | 34386935 | Hepatol Int | First-in-Asian double-blind randomized trial to assess the efficacy and safety of insulin sensitizer in nonalcoholic steatohepatitis patients. | 2021 | Details |
| A02402 | 34385479 | Sci Rep | Fatty liver index as a predictor for type 2 diabetes in subjects with normoglycemia in a nationwide cohort study. | 2021 | Details |
| A02406 | 34384565 | J Pharmacol Sci | Protective effect of SGL5213, a potent intestinal sodium-glucose cotransporter 1 inhibitor, in nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A02412 | 34382947 | Am J Gastroenterol | Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02428 | 34374253 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | [Effects of GPR81 agonist on insulin resistance in rats with nonalcoholic fatty liver disease]. | 2021 | Details |
| A02429 | 34374198 | J Dig Dis | Serum syndecan-4 is associated with nonalcoholic fatty liver disease. | 2021 | Details |
| A02432 | 34372774 | BMC Gastroenterol | Obesity and metabolic abnormalities as risks of alcoholic fatty liver in men: NAGALA study. | 2021 | Details |
| A02434 | 34372491 | Viruses | Findings from Studies Are Congruent with Obesity Having a Viral Origin, but What about Obesity-Related NAFLD? | 2021 | Details |
| A02435 | 34371968 | Nutrients | The Emerging Role of Sfrp5 and Wnt5a in the Pathogenesis of Obesity: Implications for a Healthy Diet and Lifestyle. | 2021 | Details |
| A02436 | 34371959 | Nutrients | Whey Protein Supplementation Improves the Glycemic Response and May Reduce Non-Alcoholic Fatty Liver Disease Related Biomarkers in Women with Polycystic Ovary Syndrome (PCOS). | 2021 | Details |
| A02440 | 34371198 | Prostaglandins Other Lipid Mediat | Lipocalin-type Prostaglandin D2 Synthase appears to function as a Novel Adipokine Preventing Adipose Dysfunction in response to a High Fat Diet. | 2021 | Details |
| A02441 | 34371126 | J Nutr Biochem | Dietary citrate acutely induces insulin resistance and markers of liver inflammation in mice. | 2021 | Details |
| A02442 | 34370929 | Biomol Concepts | Insulin resistance is positively associated with plasma cathepsin D activity in NAFLD patients. | 2021 | Details |
| A02444 | 34370215 | World J Pediatr | Increased asprosin is associated with non-alcoholic fatty liver disease in children with obesity. | 2021 | Details |
| A02445 | 34369032 | J Biochem Mol Toxicol | Shc inhibitor idebenone ameliorates liver injury and fibrosis in dietary NASH in mice. | 2021 | Details |
| A02446 | 34368214 | Front Nutr | Dietary Interventions in Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. | 2021 | Details |
| A02448 | 34367500 | World J Hepatol | Prevalence and risk factors of steatosis and advanced fibrosis using transient elastography in the United States' adolescent population. | 2021 | Details |
| A02451 | 34366846 | Front Pharmacol | Metformin Alleviates Hepatic Steatosis and Insulin Resistance in a Mouse Model of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease by Promoting Transcription Factor EB-Dependent Autophagy. | 2021 | Details |
| A02460 | 34364544 | Lancet Gastroenterol Hepatol | Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement. | 2021 | Details |
| A02461 | 34363981 | Diabetes Metab | Management of diabetes mellitus in patients with cirrhosis: An overview and joint statement. | 2021 | Details |
| A02463 | 34363644 | Mol Nutr Food Res | Oral Spermidine Targets Brown Fat and Skeletal Muscle to Mitigate Diet-Induced Obesity and Metabolic Disorders. | 2021 | Details |
| A02471 | 34360773 | Int J Mol Sci | Effect of Microbiome on Non-Alcoholic Fatty Liver Disease and the Role of Probiotics, Prebiotics, and Biogenics. | 2021 | Details |
| A02475 | 34359991 | Cells | A Narrative Review on the Role of AMPK on De Novo Lipogenesis in Non-Alcoholic Fatty Liver Disease: Evidence from Human Studies. | 2021 | Details |
| A02487 | 34356308 | Antioxidants (Basel) | Green Tea and Epigallocatechin Gallate (EGCG) for the Management of Nonalcoholic Fatty Liver Diseases (NAFLD): Insights into the Role of Oxidative Stress and Antioxidant Mechanism. | 2021 | Details |
| A02489 | 34355342 | Endocrine | Triglyceride glucose-waist to height ratio: a novel and effective marker for identifying hepatic steatosis in individuals with type 2 diabetes mellitus. | 2021 | Details |
| A02495 | 34352984 | Diabetes Metab J | 2021 Clinical Practice Guidelines for Diabetes Mellitus of the Korean Diabetes Association. | 2021 | Details |
| A02516 | 34344058 | Diabetes Metab Res Rev | Serum creatinine levels and risk of nonalcohol fatty liver disease in a middle-aged and older Chinese population: A cross-sectional analysis. | 2021 | Details |
| A02517 | 34343577 | Metabolism | Intestine-liver crosstalk in Type 2 Diabetes and non-alcoholic fatty liver disease. | 2021 | Details |
| A02520 | 34342231 | J Agric Food Chem | Phloridzin Ameliorates Lipid Deposition in High-Fat-Diet-Fed Mice with Nonalcoholic Fatty Liver Disease via Inhibiting the mTORC1/SREBP-1c Pathway. | 2021 | Details |
| A02521 | 34342168 | Physiol Rep | Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress. | 2021 | Details |
| A02527 | 34340957 | Endocrinol Diabetes Nutr (Engl Ed) | Prevalence and predictors of non-alcoholic steatohepatitis in patients with morbid obesity. | 2021 | Details |
| A02533 | 34338703 | Food Funct | Co-supplementation of camelina oil and a prebiotic is more effective for in improving cardiometabolic risk factors and mental health in patients with NAFLD: a randomized clinical trial. | 2021 | Details |
| A02535 | 34337376 | Metabol Open | The role of zinc in the prevention and treatment of nonalcoholic fatty liver disease. | 2021 | Details |
| A02544 | 34333285 | Biomed Pharmacother | Protective effects of p-coumaric acid against high-fat diet-induced metabolic dysregulation in mice. | 2021 | Details |
| A02546 | 34332979 | Life Sci | Dimethyl fumarate reduces oxidative stress, inflammation and fat deposition by modulation of Nrf2, SREBP-1c and NF-κB signaling in HFD fed mice. | 2021 | Details |
| A02553 | 34330512 | Clin Nutr ESPEN | Triglyceride glucose (TyG) index and the progression of liver fibrosis: A cross-sectional study. | 2021 | Details |
| A02558 | 34328446 | Am J Gastroenterol | The Changing Epidemiology of Liver Disease Among US Children and Adolescents From 1999 to 2016. | 2021 | Details |
| A02564 | 34327606 | Endocrine | Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats. | 2021 | Details |
| A02567 | 34326946 | World J Diabetes | Exploring new treatment options for polycystic ovary syndrome: Review of a novel antidiabetic agent SGLT2 inhibitor. | 2021 | Details |
| A02569 | 34326816 | Front Endocrinol (Lausanne) | New Mammalian Glycerol-3-Phosphate Phosphatase: Role in β-Cell, Liver and Adipocyte Metabolism. | 2021 | Details |
| A02579 | 34324263 | Diabetes Obes Metab | Non-alcoholic fatty liver disease-related risk of cardiovascular disease and other cardiac complications. | 2021 | Details |
| A02580 | 34324132 | Indian J Pediatr | Usefulness of Controlled Attenuation Parameter for Identification and Grading of Nonalcoholic Fatty Liver Disease in Adolescents with Obesity. | 2021 | Details |
| A02588 | 34321846 | World J Gastroenterol | Advances in paediatric nonalcoholic fatty liver disease: Role of lipidomics. | 2021 | Details |
| A02590 | 34321567 | Sci Rep | High frequency and long persistency of ballooning hepatocyte were associated with glucose intolerance in patients with severe obesity. | 2021 | Details |
| A02595 | 34321005 | Lipids Health Dis | Usefulness of the triglyceride glucose-body mass index in evaluating nonalcoholic fatty liver disease: insights from a general population. | 2021 | Details |
| A02598 | 34320173 | Am J Clin Nutr | The effects of resveratrol supplementation in patients with type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease: an umbrella review of meta-analyses of randomized controlled trials. | 2021 | Details |
| A02601 | 34314787 | Adv Drug Deliv Rev | Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis. | 2021 | Details |
| A02609 | 34311022 | Diabetes Res Clin Pract | Pioglitazone even at low dosage improves NAFLD in type 2 diabetes: clinical and pathophysiological insights from a subgroup of the TOSCA.IT randomised trial. | 2021 | Details |
| A02614 | 34309471 | Ann Med | Fatty liver index predicts incident risk of prediabetes, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A02622 | 34306045 | PPAR Res | Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-α/γ) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment Counteracts the High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02629 | 34303827 | Clin Res Hepatol Gastroenterol | Metabolically healthy and unhealthy obesity and the progression of liver fibrosis: A cross-sectional study. | 2021 | Details |
| A02632 | 34302259 | Endocrine | Prospective assessment of liver stiffness by shear wave elastography in childhood obesity: a pilot study. | 2021 | Details |
| A02633 | 34300354 | J Clin Med | Albuminuria Is Associated with Hepatic Iron Load in Patients with Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome. | 2021 | Details |
| A02635 | 34300227 | J Clin Med | Insulin Resistance Is Not Increased in Inflammatory Bowel Disease Patients but Is Related to Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02638 | 34299336 | Int J Mol Sci | Non-Coding RNAs: Novel Players in Insulin Resistance and Related Diseases. | 2021 | Details |
| A02665 | 34292604 | Hepatology | Salidroside Activates the AMP-Activated Protein Kinase Pathway to Suppress Nonalcoholic Steatohepatitis in Mice. | 2021 | Details |
| A02667 | 34292171 | Eur J Endocrinol | A recurrent familial partial lipodystrophy due to a monoallelic or biallelic LMNA founder variant highlights the multifaceted cardiac manifestations of metabolic laminopathies. | 2021 | Details |
| A02674 | 34289506 | Semin Liver Dis | Novel Antidiabetic Strategies and Diabetologists' Views in Nonalcoholic Steatohepatitis. | 2021 | Details |
| A02676 | 34289181 | J Gastroenterol Hepatol | Circulating tumor necrosis factor-α levels in non-alcoholic fatty liver disease: A systematic review and a meta-analysis. | 2021 | Details |
| A02677 | 34289064 | J Clin Endocrinol Metab | Hepatic Fat in Early Childhood Is Independently Associated With Estimated Insulin Resistance: The Healthy Start Study. | 2021 | Details |
| A02684 | 34284789 | Nutr Metab (Lond) | Modulation and bioinformatics screening of hepatic mRNA-lncRNAs (HML) network associated with insulin resistance in prediabetic and exercised mice. | 2021 | Details |