Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04936 | 33444607 | Metabolism | Mitochondrial dynamics and nonalcoholic fatty liver disease (NAFLD): new perspectives for a fairy-tale ending? | 2021 | Details |
| A04951 | 33439102 | Am J Physiol Gastrointest Liver Physiol | Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling. | 2021 | Details |
| A04959 | 33437892 | Transl Gastroenterol Hepatol | Mitochondrial dysfunction in nonalcoholic fatty liver disease and alcohol related liver disease. | 2021 | Details |
| A04978 | 33429022 | Free Radic Biol Med | Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress. | 2021 | Details |
| A04986 | 33424768 | Front Endocrinol (Lausanne) | Harnessing Muscle-Liver Crosstalk to Treat Nonalcoholic Steatohepatitis. | 2020 | Details |
| A04990 | 33422521 | Chem Biol Interact | Phenolic-rich smoothie consumption ameliorates non-alcoholic fatty liver disease in obesity mice by increasing antioxidant response. | 2021 | Details |
| A04992 | 33421970 | Turk J Med Sci | The effect of 1,25-dihydroxyvitamin D3 on liver damage, oxidative stress, and advanced glycation end products in experimental nonalcoholic- and alcoholic- fatty liver disease | 2021 | Details |
| A04997 | 33421258 | J Biochem Mol Toxicol | The protective effects of trelagliptin on high-fat diet-induced nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A05003 | 33417955 | Life Sci | Sacran, a sulfated polysaccharide, suppresses the absorption of lipids and modulates the intestinal flora in non-alcoholic steatohepatitis model rats. | 2021 | Details |
| A05009 | 33411984 | J Appl Microbiol | The interplay between host cellular and gut microbial metabolism in NAFLD development and prevention. | 2021 | Details |
| A05011 | 33411880 | Food Funct | Berbamine induced activation of the SIRT1/LKB1/AMPK signaling axis attenuates the development of hepatic steatosis in high-fat diet-induced NAFLD rats. | 2021 | Details |
| A05019 | 33409397 | Transl Gastroenterol Hepatol | Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). | 2021 | Details |
| A05025 | 33406763 | Int J Mol Sci | Immunity as Cornerstone of Non-Alcoholic Fatty Liver Disease: The Contribution of Oxidative Stress in the Disease Progression. | 2021 | Details |
| A05043 | 33396939 | Int J Mol Sci | Deletion of KLF10 Leads to Stress-Induced Liver Fibrosis upon High Sucrose Feeding. | 2020 | Details |
| A05045 | 33396456 | Antioxidants (Basel) | Antioxidant and Hypolipidemic Activity of Açai Fruit Makes It a Valuable Functional Food. | 2020 | Details |
| A05070 | 33388433 | Free Radic Biol Med | Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress. | 2021 | Details |
| A05073 | 33387664 | Mitochondrion | Mitochondrial dysfunction as a mechanistic biomarker in patients with non-alcoholic fatty liver disease (NAFLD). | 2020 | Details |
| A05087 | 33382757 | PLoS One | Nut consumption and the prevalence and severity of non-alcoholic fatty liver disease. | 2020 | Details |
| A05093 | 33379170 | Molecules | Synthesis, Photoisomerization, Antioxidant Activity, and Lipid-Lowering Effect of Ferulic Acid and Feruloyl Amides. | 2020 | Details |
| A05104 | 33374984 | Molecules | Honeybee Pollen Extracts Reduce Oxidative Stress and Steatosis in Hepatic Cells. | 2020 | Details |
| A05112 | 33371482 | Biomolecules | Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants. | 2020 | Details |
| A05129 | 33362721 | Front Endocrinol (Lausanne) | Oxidation-Specific Epitopes in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05188 | 33342543 | J Hepatol | Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis. | 2020 | Details |
| A05207 | 33339155 | Antioxidants (Basel) | N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature. | 2020 | Details |
| A05212 | 33337101 | Compr Rev Food Sci Food Saf | Phytosterols and their derivatives: Potential health-promoting uses against lipid metabolism and associated diseases, mechanism, and safety issues. | 2020 | Details |
| A05222 | 33333850 | J Clin Med | The Vicious Circle of Hepatic Glucagon Resistance in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05233 | 33329394 | Front Endocrinol (Lausanne) | Aerobic Exercise Training Exerts Beneficial Effects Upon Oxidative Metabolism and Non-Enzymatic Antioxidant Defense in the Liver of Leptin Deficiency Mice. | 2020 | Details |
| A05253 | 33322323 | Animals (Basel) | GC-TOF-MS-Based Metabolomics Analyses of Liver and Intestinal Contents in the Overfed vs. Normally-Fed Geese. | 2020 | Details |
| A05265 | 33319629 | Drug Chem Toxicol | Effects of Rhus coriaria L. hydroalcoholic extract on the lipid and antioxidant profile in high fat diet-induced hepatic steatosis in rats. | 2018 | Details |
| A05304 | 33308101 | Am J Chin Med | Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo. | 2020 | Details |
| A05329 | 33300526 | Food Funct | Improvement of the hepatic lipid status in intrauterine growth retarded pigs by resveratrol is related to the inhibition of mitochondrial dysfunction, oxidative stress and inflammation. | 2020 | Details |
| A05331 | 33299871 | Biomed Res Int | Protective Role of Probiotic Supplements in Hepatic Steatosis: A Rat Model Study. | 2020 | Details |
| A05337 | 33298075 | Lipids Health Dis | Hepatic lipid profile in mice fed a choline-deficient, low-methionine diet resembles human non-alcoholic fatty liver disease. | 2020 | Details |
| A05351 | 33290156 | Can J Physiol Pharmacol | Theobromine ameliorates nonalcoholic fatty liver disease by regulating hepatic lipid metabolism via mTOR signaling pathway in vivo and in vitro. | 2020 | Details |
| A05362 | 33282271 | Food Sci Nutr | Protective effect of celastrol on type 2 diabetes mellitus with nonalcoholic fatty liver disease in mice. | 2020 | Details |
| A05365 | 33281601 | Front Pharmacol | The Target MicroRNAs and Potential Underlying Mechanisms of Yiqi-Bushen-Tiaozhi Recipe against-Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A05380 | 33276146 | Mol Metab | Mitochondrial oxidative function in NAFLD: Friend or foe? | 2020 | Details |
| A05388 | 33273997 | Oxid Med Cell Longev | Plant Sterol Ester of α-Linolenic Acid Attenuates Nonalcoholic Fatty Liver Disease by Rescuing the Adaption to Endoplasmic Reticulum Stress and Enhancing Mitochondrial Biogenesis. | 2019 | Details |
| A05393 | 33272734 | Gastroenterol Hepatol | Silencing HIF-1α aggravates non-alcoholic fatty liver disease in vitro through inhibiting PPAR-α/ANGPTL4 singling pathway. | 2020 | Details |
| A05419 | 33266488 | Int J Mol Sci | Interplay between Oxidative Stress and Metabolic Derangements in Non-Alcoholic Fatty Liver Disease: The Role of Selenoprotein P. | 2020 | Details |
| A05421 | 33264665 | J Nutr Biochem | Hepatic metabolic adaptation and adipose tissue expansion are altered in mice with steatohepatitis induced by high-fat high sucrose diet. | 2020 | Details |
| A05422 | 33263565 | J Endocrinol | Overexpression of the Lias gene attenuates hepatic steatosis in Leprdb/db mice. | 2021 | Details |
| A05425 | 33261044 | Int J Mol Sci | Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver. | 2020 | Details |
| A05438 | 33257471 | Gut | Hepatic Krüppel-like factor 16 (KLF16) targets PPARα to improve steatohepatitis and insulin resistance. | 2020 | Details |
| A05447 | 33253604 | Pharm Biol | Effects of wogonoside on the inflammatory response and oxidative stress in mice with nonalcoholic fatty liver disease. | 2020 | Details |
| A05493 | 33234364 | Phytomedicine | Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe-/-mice: role of SIRT1. | 2020 | Details |
| A05499 | 33229553 | Proc Natl Acad Sci U S A | Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease. | 2020 | Details |
| A05514 | 33220492 | Mol Metab | Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans. | 2020 | Details |
| A05546 | 33212947 | Nutrients | Fructose, Omega 3 Fatty Acids, and Vitamin E: Involvement in Pediatric Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05566 | 33204675 | Can J Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease and Sarcopenia: Where Do We Stand? | 2020 | Details |
| A05568 | 33204402 | Oxid Med Cell Longev | Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice. | 2020 | Details |
| A05577 | 33202166 | J Med Food | Water Extract of Artemisia annua L. Exhibits Hepatoprotective Effects Through Improvement of Lipid Accumulation and Oxidative Stress-Induced Cytotoxicity. | 2020 | Details |
| A05590 | 33197790 | Environ Int | Unravelling the metabolic alterations of liver damage induced by thirdhand smoke. | 2020 | Details |
| A05631 | 33182043 | Int Immunopharmacol | Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice. | 2020 | Details |
| A05632 | 33182038 | Int Immunopharmacol | Resolvin D1 mitigates non-alcoholic steatohepatitis by suppressing the TLR4-MyD88-mediated NF-κB and MAPK pathways and activating the Nrf2 pathway in mice. | 2020 | Details |
| A05678 | 33163831 | Hepatol Commun | Loss of Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Links Nonalcoholic Steatohepatitis to Atherosclerosis. | 2020 | Details |
| A05695 | 33152943 | Biomed Pharmacother | The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling. | 2020 | Details |
| A05702 | 33149855 | Iran J Basic Med Sci | Effect of soy consumption on liver enzymes, lipid profile, anthropometry indices, and oxidative stress in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of clinical trials. | 2020 | Details |
| A05703 | 33149804 | Oxid Med Cell Longev | Role of Oxidative Stress in Hepatic and Extrahepatic Dysfunctions during Nonalcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A05713 | 33144913 | Oxid Med Cell Longev | Amelioration by Idesia polycarpa Maxim. var. vestita Diels. of Oleic Acid-Induced Nonalcoholic Fatty Liver in HepG2 Cells through Antioxidant and Modulation of Lipid Metabolism. | 2020 | Details |
| A05715 | 33144092 | Peptides | Chemerin/CMKLR1 ameliorates nonalcoholic steatohepatitis by promoting autophagy and alleviating oxidative stress through the JAK2-STAT3 pathway. | 2020 | Details |
| A05736 | 33139607 | Nutrients | Nuts and Non-Alcoholic Fatty Liver Disease: Are Nuts Safe for Patients with Fatty Liver Disease? | 2020 | Details |
| A05742 | 33135718 | Food Funct | Integrative transcriptomics and metabolomics explore the mechanism of kaempferol on improving nonalcoholic steatohepatitis. | 2020 | Details |
| A05750 | 33132768 | ScientificWorldJournal | Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin. | 2020 | Details |
| A05759 | 33131062 | Hepatology | Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin-Like Phospholipase Domain Containing 3-Mediated Acceleration of Steatohepatitis. | 2021 | Details |
| A05792 | 33115780 | Cancer Prev Res (Phila) | Targeting the Cholecystokinin Receptor: A Novel Approach for Treatment and Prevention of Hepatocellular Cancer. | 2020 | Details |
| A05795 | 33114564 | Nutrients | Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation. | 2020 | Details |
| A05798 | 33114299 | Antioxidants (Basel) | Comparative Effects of Pterostilbene and Its Parent Compound Resveratrol on Oxidative Stress and Inflammation in Steatohepatitis Induced by High-Fat High-Fructose Feeding. | 2020 | Details |
| A05800 | 33114278 | Antioxidants (Basel) | Consumption of Spinach and Tomato Modifies Lipid Metabolism, Reducing Hepatic Steatosis in Rats. | 2020 | Details |
| A05801 | 33114221 | Antioxidants (Basel) | Auranofin Attenuates Non-Alcoholic Fatty Liver Disease by Suppressing Lipid Accumulation and NLRP3 Inflammasome-Mediated Hepatic Inflammation In Vivo and In Vitro. | 2020 | Details |
| A05802 | 33114148 | Int J Mol Sci | Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases. | 2020 | Details |
| A05807 | 33113501 | Phytomedicine | Modulation of IR as a therapeutic target to prevent NASH using NRF from Diceratella elliptica (DC.) jonsell. Strong Nrf2 and leptin inducer as well as NF-kB inhibitor. | 2020 | Details |
| A05820 | 33106141 | Curr Mol Med | Critical Role of NFκB in the Pathogenesis of Non-alcoholic Fatty Liver Disease: A Widespread Key Regulator. | 2021 | Details |
| A05821 | 33106137 | Curr Pharm Des | Therapeutic effect of Prdx1 on NAFLD mice may be related to the activation of Nrf-2/HO-1 pathway. | 2020 | Details |
| A05828 | 33105604 | Int J Mol Sci | Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor. | 2020 | Details |
| A05857 | 33098868 | Arch Biochem Biophys | miR-34a regulates lipid metabolism by targeting SIRT1 in non-alcoholic fatty liver disease with iron overload. | 2020 | Details |
| A05863 | 33096235 | J Nutr Biochem | Nobiletin alleviates high-fat diet-induced nonalcoholic fatty liver disease by modulating AdipoR1 and gp91phox expression in rats. | 2020 | Details |
| A05876 | 33092030 | Int J Mol Sci | Accumulation of 8-hydroxydeoxyguanosine, L-arginine and Glucose Metabolites by Liver Tumor Cells Are the Important Characteristic Features of Metabolic Syndrome and Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis. | 2020 | Details |
| A05882 | 33090099 | Turk J Gastroenterol | Morphological evaluation of the effects of exercise on high-fat-diet-induced liver damage in rats. | 2020 | Details |
| A05919 | 33076261 | Antioxidants (Basel) | Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response. | 2020 | Details |
| A05931 | 33072455 | Cureus | Pleiotropic Effects of Statins in the Light of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A05936 | 33071788 | Front Pharmacol | Veratrilla baillonii Franch Could Alleviate Lipid Accumulation in LO2 Cells by Regulating Oxidative, Inflammatory, and Lipid Metabolic Signaling Pathways. | 2020 | Details |
| A05949 | 33066113 | Int J Mol Sci | Chymase as a Possible Therapeutic Target for Amelioration of Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A05960 | 33061293 | Drug Des Devel Ther | Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice. | 2020 | Details |
| A05962 | 33060605 | Sci Rep | Clusterin overexpression protects against western diet-induced obesity and NAFLD. | 2020 | Details |
| A05964 | 33060043 | Dig Liver Dis | Antioxidant activity of Hydroxytyrosol and Vitamin E reduces systemic inflammation in children with paediatric NAFLD. | 2020 | Details |
| A06020 | 33037249 | Sci Rep | Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis. | 2020 | Details |
| A06030 | 33034193 | J Agric Food Chem | High-Fat Proteins Drive Dynamic Changes in Gut Microbiota, Hepatic Metabolome, and Endotoxemia-TLR-4-NFκB-Mediated Inflammation in Mice. | 2020 | Details |
| A06050 | 33027743 | Biomed Pharmacother | Sagittaria sagittifolia polysaccharide interferes with arachidonic acid metabolism in non-alcoholic fatty liver disease mice via Nrf2/HO-1 signaling pathway. | 2020 | Details |
| A06068 | 33022287 | Food Chem Toxicol | MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement. | 2020 | Details |
| A06071 | 33017610 | J Nutr Biochem | Liver lipidome signature and metabolic pathways in nonalcoholic fatty liver disease induced by a high-sugar diet. | 2020 | Details |
| A06076 | 33015093 | Front Med (Lausanne) | Association Between Leukocyte Mitochondrial DNA Copy Number and Non-alcoholic Fatty Liver Disease in a Chinese Population Is Mediated by 8-Oxo-2'-Deoxyguanosine. | 2020 | Details |
| A06118 | 32998725 | BMC Med | Non-alcoholic fatty liver disease (NAFLD) as a neglected metabolic companion of psychiatric disorders: common pathways and future approaches. | 2020 | Details |
| A06126 | 32996726 | Minerva Med | Adiponectin alleviates nonalcoholic fatty liver injury via regulating oxidative stress in liver cells. | 2020 | Details |
| A06135 | 32993055 | Int J Mol Sci | Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress. | 2020 | Details |
| A06136 | 32992548 | Antioxidants (Basel) | Involvement of HO-1 and Autophagy in the Protective Effect of Magnolol in Hepatic Steatosis-Induced NLRP3 Inflammasome Activation In Vivo and In Vitro. | 2020 | Details |
| A06152 | 32985285 | Free Radic Res | Negative association between antioxidant vitamin intake and non-alcoholic fatty liver disease in Chinese non-diabetic adults: mediation models involving superoxide dismutase. | 2020 | Details |
| A06153 | 32985239 | Nat Prod Res | Hepatoprotective effect of total flavonoids from Glycyrrhiza uralensis Fisch in liver injury mice. | 2020 | Details |
| A06157 | 32982804 | Front Physiol | Newly Discovered Adipokines: Pathophysiological Link Between Obesity and Cardiometabolic Disorders. | 2020 | Details |
| A06179 | 32978374 | Cell Death Dis | Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver? | 2020 | Details |