Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A18302 | 27227672 | PLoS One | Contribution of Cyclooxygenase End Products and Oxidative Stress to Intrahepatic Endothelial Dysfunction in Early Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A18306 | 27222915 | Ann Med | Liver fat accumulation is associated with circulating PCSK9. | 2016 | Details |
| A18310 | 27220852 | Obes Surg | Modified thresholds for fibrosis risk scores in nonalcoholic fatty liver disease are necessary in the obese. | 2017 | Details |
| A18321 | 27213358 | Int J Mol Sci | The Natural Course of Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A18328 | 27207510 | Diabetes | Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD. | 2016 | Details |
| A18334 | 27198736 | Dig Liver Dis | Reduced lysosomal acid lipase activity - A potential role in the pathogenesis of non alcoholic fatty liver disease in pediatric patients. | 2016 | Details |
| A18340 | 27196584 | Gut | Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation. | 2016 | Details |
| A18342 | 27194895 | J Clin Exp Hepatol | Coffee and Liver Disease. | 2016 | Details |
| A18358 | 27184636 | Saudi J Gastroenterol | An open-label randomized control study to compare the efficacy of vitamin e versus ursodeoxycholic acid in nondiabetic and noncirrhotic Indian NAFLD patients. | 2017 | Details |
| A18360 | 27183219 | Hepatol Res | Controlled attenuation parameter is correlated with actual hepatic fat content in patients with non-alcoholic fatty liver disease with none-to-mild obesity and liver fibrosis. | 2016 | Details |
| A18364 | 27181051 | Sci Rep | Ces3/TGH Deficiency Attenuates Steatohepatitis. | 2016 | Details |
| A18366 | 27180087 | Toxicol Lett | Mainstream cigarette smoke accelerates the progression of nonalcoholic steatohepatitis by modulating Kupffer cell-mediated hepatocellular apoptosis in adolescent mice. | 2016 | Details |
| A18368 | 27179602 | Environ Toxicol Pharmacol | Fatty acid composition in serum correlates with that in the liver and non-alcoholic fatty liver disease activity scores in mice fed a high-fat diet. | 2016 | Details |
| A18370 | 27178444 | Liver Int | Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome. | 2016 | Details |
| A18373 | 27175704 | Medicine (Baltimore) | Accumulation of Intrahepatic TNF-α-Producing NKp44+ NK Cells Correlates With Liver Fibrosis and Viral Load in Chronic HCV Infection. | 2016 | Details |
| A18375 | 27174364 | Br J Pharmacol | Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. | 2016 | Details |
| A18382 | 27172901 | Oncotarget | IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis. | 2016 | Details |
| A18396 | 27161854 | Scand J Gastroenterol | Contrast-enhanced ultrasonography could be a non-invasive method for differentiating none or mild from severe fibrosis in patients with biopsy proven non-alcoholic fatty liver disease. | 2016 | Details |
| A18398 | 27160697 | Dig Liver Dis | Non-alcoholic fatty liver disease fibrosis score and preclinical vascular damage in morbidly obese patients. | 2016 | Details |
| A18411 | 27151181 | J Hepatol | Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease. | 2016 | Details |
| A18412 | 27151177 | J Hepatol | Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial. | 2016 | Details |
| A18413 | 27150853 | Intern Med | Significance of Hepatic Insulin Clearance in Patients with Chronic Hepatitis C and Non-alcoholic Fatty Liver Disease. | 2016 | Details |
| A18414 | 27150500 | Scand J Gastroenterol | The PNPLA3 rs738409 C > G polymorphism is associated with the risk of progression to cirrhosis in NAFLD patients. | 2016 | Details |
| A18444 | 29182828 | Lijec Vjesn | APPROACH TO THE PATIENT WITH NONALCOHOLIC FATTY LIVER DISEASE. | 2016 | Details |
| A18445 | 29182821 | Rinsho Byori | [Present State of Non-B Non-C Liver Disease-and Its Monitoring.] | 2016 | Details |
| A18448 | 27128911 | Int J Mol Sci | Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD-A Systematic Review. | 2016 | Details |
| A18457 | 27122660 | World J Gastroenterol | Nonalcoholic fatty liver disease as a multi-systemic disease. | 2016 | Details |
| A18458 | 27121255 | Int J Obes (Lond) | Intervention with a caspase-1 inhibitor reduces obesity-associated hyperinsulinemia, non-alcoholic steatohepatitis and hepatic fibrosis in LDLR-/-.Leiden mice. | 2016 | Details |
| A18464 | 27110380 | BMJ Open Gastroenterol | Statins, antidiabetic medications and liver histology in patients with diabetes with non-alcoholic fatty liver disease. | 2016 | Details |
| A18466 | 27110262 | Hepat Mon | Ginger Supplementation in Nonalcoholic Fatty Liver Disease: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. | 2016 | Details |
| A18475 | 27104887 | J Physiol | Aerobic exercise training in the treatment of non-alcoholic fatty liver disease related fibrosis. | 2016 | Details |
| A18477 | 27104526 | Int J Mol Sci | NAFLD and Increased Aortic Stiffness: Parallel or Common Physiopathological Mechanisms? | 2016 | Details |
| A18479 | 27102725 | Liver Int | The macrophage activation marker sCD163 is associated with morphological disease stages in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A18482 | 27100443 | Medicine (Baltimore) | The Presence of White Matter Lesions Is Associated With the Fibrosis Severity of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18484 | 27101131 | Diabetologia | Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions. | 2016 | Details |
| A18485 | 27099853 | Adv Biomed Res | Comparison of liver enzymes level and sonographic findings value with liver biopsy findings in nonalcoholic fatty liver disease patients. | 2016 | Details |
| A18486 | 27099536 | Hepat Med | Autophagy: a new target for nonalcoholic fatty liver disease therapy. | 2016 | Details |
| A18494 | 27091184 | Diabetologia | Diagnosis of non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A18495 | 27091156 | Cell Mol Life Sci | Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease. | 2016 | Details |
| A18503 | 27086596 | J Pathol Transl Med | Interobserver Agreement on Pathologic Features of Liver Biopsy Tissue in Patients with Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18504 | 27086005 | Curr Gastroenterol Rep | Pediatric Non-alcoholic Fatty Liver Disease. | 2016 | Details |
| A18510 | 27083512 | J Gastroenterol Hepatol | Adiponectin regulates aquaglyceroporin expression in hepatic stellate cells altering their functional state. | 2017 | Details |
| A18514 | 27077854 | Int J Mol Sci | Role of Serum Uric Acid and Ferritin in the Development and Progression of NAFLD. | 2016 | Details |
| A18515 | 27077736 | PLoS One | Association of Circulating Serum miR-34a and miR-122 with Dyslipidemia among Patients with Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A18517 | 27076758 | World J Gastroenterol | Phosphatase and tensin homolog is a differential diagnostic marker between nonalcoholic and alcoholic fatty liver disease. | 2016 | Details |
| A18518 | 27076501 | Hum Reprod | Non-alcoholic fatty liver disease is associated with insulin resistance and lipid accumulation product in women with polycystic ovary syndrome. | 2016 | Details |
| A18520 | 27075663 | BMC Pharmacol Toxicol | Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats. | 2016 | Details |
| A18521 | 27074921 | Dig Dis Sci | Treatment with Oxidized Phospholipids Directly Inhibits Nonalcoholic Steatohepatitis and Liver Fibrosis Without Affecting Steatosis. | 2016 | Details |
| A18522 | 27074850 | Hepatol Int | Impact of circulating miR-122 for histological features and hepatocellular carcinoma of nonalcoholic fatty liver disease in Japan. | 2016 | Details |
| A18524 | 27072576 | Oncotarget | Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma. | 2016 | Details |
| A18532 | 27064133 | Liver Int | Elevated serum ferritin is associated with increased mortality in non-alcoholic fatty liver disease after 16 years of follow-up. | 2016 | Details |
| A18539 | 27063274 | Clin Liver Dis | Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18540 | 27063273 | Clin Liver Dis | Effect of Weight Loss, Diet, Exercise, and Bariatric Surgery on Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18542 | 27063271 | Clin Liver Dis | Progression and Natural History of Nonalcoholic Fatty Liver Disease in Adults. | 2015 | Details |
| A18543 | 27063270 | Clin Liver Dis | Histology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Adults and Children. | 2015 | Details |
| A18544 | 27063269 | Clin Liver Dis | Clinical Presentation and Patient Evaluation in Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18545 | 27063268 | Clin Liver Dis | Nonalcoholic Fatty Liver Disease and the Gut Microbiome. | 2015 | Details |
| A18553 | 27061197 | Aliment Pharmacol Ther | Review article: emerging anti-fibrotic therapies in the treatment of non-alcoholic steatohepatitis. | 2016 | Details |
| A18554 | 28702244 | Clin Diabetes Endocrinol | Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in patients with Type 2 Diabetes Mellitus. | 2016 | Details |
| A18556 | 27060021 | Clin Nutr | Coffee and tea consumption in relation with non-alcoholic fatty liver and metabolic syndrome: A systematic review and meta-analysis of observational studies. | 2016 | Details |
| A18557 | 27059980 | Dig Dis Sci | APOC3 rs2070666 Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases. | 2016 | Details |
| A18558 | 27057890 | Medicine (Baltimore) | Steatosis Grade is the Most Important Risk Factor for Development of Endothelial Dysfunction in NAFLD. | 2016 | Details |
| A18566 | 27054361 | Obes Facts | Impact of Apolipoprotein B on Hepatosteatosis in a Population Infected with Hepatitis C Virus: A Cross-Sectional Observational Study. | 2016 | Details |
| A18570 | 27053232 | Diabetologia | EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease: is universal screening appropriate? | 2016 | Details |
| A18573 | 27052013 | Dig Dis Sci | Lifestyle and Dietary Interventions in the Management of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18577 | 27051590 | BBA Clin | Diabetic and dyslipidaemic morbidly obese exhibit more liver alterations compared with healthy morbidly obese. | 2016 | Details |
| A18578 | 27049488 | Ann Hepatol | Nonalcoholic steatohepatitis in morbid obese patients: coffee consumption vs. disease severity. | 2017 | Details |
| A18579 | 27049380 | Int J Mol Sci | Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome after Liver Transplant. | 2016 | Details |
| A18608 | 27037502 | Int J Exp Pathol | Pathological characterization and morphometric analysis of hepatic lesions in SHRSP5/Dmcr, an experimental non-alcoholic steatohepatitis model, induced by high-fat and high-cholesterol diet. | 2016 | Details |
| A18609 | 27036545 | BMC Pediatr | Association of maternal diabetes/glycosuria and pre-pregnancy body mass index with offspring indicators of non-alcoholic fatty liver disease. | 2016 | Details |
| A18615 | 27032381 | J Hepatol | Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis. | 2016 | Details |
| A18617 | 27030186 | Ter Arkh | [Evaluation of cardiovascular remodeling and epicardial fat thickness in patients with chronic heart failure and metabolic syndrome]. | 2016 | Details |
| A18633 | 28868449 | GE Port J Gastroenterol | Microbiota Modulation With Synbiotic Decreases Liver Fibrosis in a High Fat Choline Deficient Diet Mice Model of Non-Alcoholic Steatohepatitis (NASH). | 2016 | Details |
| A18639 | 27019638 | Int J Biol Sci | Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury. | 2016 | Details |
| A18643 | 27018279 | Geriatr Gerontol Int | Involvement of senescence marker protein-30 in glucose metabolism disorder and non-alcoholic fatty liver disease. | 2016 | Details |
| A18645 | 27017224 | Dig Dis Sci | Fibrosis Assessment in Nonalcoholic Fatty Liver Disease (NAFLD) in 2016. | 2016 | Details |
| A18650 | 27015215 | Medicine (Baltimore) | The Application of Liver Stiffness Measurement in Residents Without Overt Liver Diseases Through a Community-Based Screening Program. | 2016 | Details |
| A18651 | 27015186 | Medicine (Baltimore) | Interactions of a PPARGC1A Variant and a PNPLA3 Variant Affect Nonalcoholic Steatohepatitis in Severely Obese Taiwanese Patients. | 2016 | Details |
| A18655 | 27012620 | J Nutr Biochem | Electronegative LDL is linked to high-fat, high-cholesterol diet-induced nonalcoholic steatohepatitis in hamsters. | 2015 | Details |
| A18660 | 27006950 | Biomed Res Int | Liver Stiffness Measurement in Psoriasis: Do Metabolic or Disease Factors Play the Important Role? | 2016 | Details |
| A18661 | 27006654 | Gastroenterol Res Pract | A Comprehensive Updated Review of Pharmaceutical and Nonpharmaceutical Treatment for NAFLD. | 2016 | Details |
| A18664 | 27005620 | Int J Mol Sci | Type 2 Diabetes in Non-Alcoholic Fatty Liver Disease and Hepatitis C Virus Infection--Liver: The "Musketeer" in the Spotlight. | 2016 | Details |
| A18666 | 27004022 | Clujul Med | Hyaluronic acid as a biomarker of fibrosis in chronic liver diseases of different etiologies. | 2016 | Details |
| A18668 | 27003601 | Gastroenterology | Biopsy and Noninvasive Methods to Assess Progression of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18671 | 27003143 | Dig Dis Sci | Novel Pharmacotherapy Options for NASH. | 2016 | Details |
| A18672 | 27003142 | Dig Dis Sci | Natural History of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18673 | 27002799 | Am J Gastroenterol | Vitamin D Deficiency Is Associated With Increased Risk of Non-alcoholic Steatohepatitis in Adults With Non-alcoholic Fatty Liver Disease: Possible Role for MAPK and NF-κB? | 2016 | Details |
| A18674 | 27002798 | Am J Gastroenterol | Novel 3D Magnetic Resonance Elastography for the Noninvasive Diagnosis of Advanced Fibrosis in NAFLD: A Prospective Study. | 2016 | Details |
| A18676 | 27002630 | PLoS One | Evaluation of Fucosylated Haptoglobin and Mac-2 Binding Protein as Serum Biomarkers to Estimate Liver Fibrosis in Patients with Chronic Hepatitis C. | 2016 | Details |
| A18678 | 27002005 | Gut | Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease. | 2016 | Details |
| A18681 | 26999107 | Int J Mol Sci | Telomeres, NAFLD and Chronic Liver Disease. | 2016 | Details |
| A18682 | 26999105 | Int J Mol Sci | Mitochondrial Molecular Pathophysiology of Nonalcoholic Fatty Liver Disease: A Proteomics Approach. | 2016 | Details |
| A18686 | 26997950 | Gastroenterol Res Pract | Pentraxin 3 Is a Predictor for Fibrosis and Arterial Stiffness in Patients with Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18687 | 26997642 | Hepatol Res | Classification of patients with non-alcoholic fatty liver disease using rapid immunoassay of serum type IV collagen compared with liver histology and other fibrosis markers. | 2016 | Details |
| A18689 | 26997539 | Metabolism | Epidemiology and natural history of non-alcoholic fatty liver disease. | 2016 | Details |
| A18692 | 26997214 | Saudi J Gastroenterol | Treatment of nonalcoholic fatty liver disease: Where do we stand? an overview. | 2017 | Details |
| A18696 | 26996383 | J Surg Oncol | The association between non-alcoholic steatohepatitis and intrahepatic cholangiocarcinoma: A hospital based case-control study. | 2016 | Details |
| A18703 | 26991726 | Liver Int | The ability of Hepascore to predict liver fibrosis in chronic liver disease: a meta-analysis. | 2016 | Details |
| A18707 | 26989059 | Obes Surg | Prevalence of Liver Fibrosis and its Association with Non-invasive Fibrosis and Metabolic Markers in Morbidly Obese Patients with Vitamin D Deficiency. | 2016 | Details |
| A18710 | 26985892 | Int J Mol Sci | Extracellular Vesicles: A New Frontier in Biomarker Discovery for Non-Alcoholic Fatty Liver Disease. | 2016 | Details |