Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A47040 | 28476407 | Toxicol Appl Pharmacol | Curcumin improves alcoholic fatty liver by inhibiting fatty acid biosynthesis. | 2017 | Details |
| A47042 | 28424943 | Dig Dis Sci | Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice. | 2017 | Details |
| A47043 | 28274894 | J Ethnopharmacol | Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and anti-inflammation in livers of chronic-alcohol fed mice. | 2017 | Details |
| A47044 | 28228158 | Lipids Health Dis | Flaxseed oil ameliorates alcoholic liver disease via anti-inflammation and modulating gut microbiota in mice. | 2017 | Details |
| A47052 | 27824131 | Sci Rep | Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice. | 2016 | Details |
| A47055 | 27746183 | Am J Pathol | Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury. | 2016 | Details |
| A47057 | 27666676 | Sci Rep | Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice. | 2016 | Details |
| A47058 | 27630043 | Nat Commun | MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C. | 2016 | Details |
| A47059 | 27455313 | Nutrients | Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response. | 2016 | Details |
| A47062 | 27346657 | Sci Rep | The Cannabinoid Receptor 2 Protects Against Alcoholic Liver Disease Via a Macrophage Autophagy-Dependent Pathway. | 2016 | Details |
| A47068 | 26968209 | Am J Physiol Gastrointest Liver Physiol | Enhanced ethanol catabolism in orphan nuclear receptor SHP-null mice. | 2016 | Details |
| A47072 | 26858343 | Gut | Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors. | 2016 | Details |
| A47075 | 26801973 | BMC Complement Altern Med | Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease. | 2016 | Details |
| A47077 | 26637972 | Biofactors | Endogenously elevated n-3 polyunsaturated fatty acids alleviate acute ethanol-induced liver steatosis. | 2015 | Details |
| A47085 | 26497211 | Oncotarget | Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro. | 2015 | Details |
| A47087 | 26493454 | BMC Syst Biol | Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes. | 2015 | Details |
| A47088 | 26459052 | Int Immunopharmacol | Ligustrazine prevents alcohol-induced liver injury by attenuating hepatic steatosis and oxidative stress. | 2015 | Details |
| A47097 | 26025474 | Biochimie | Excessive bile acid activated NF-kappa B and promoted the development of alcoholic steatohepatitis in farnesoid X receptor deficient mice. | 2015 | Details |
| A47106 | 25892964 | Int J Biol Sci | The effects of insulin pre-administration in mice exposed to ethanol: alleviating hepatic oxidative injury through anti-oxidative, anti-apoptotic activities and deteriorating hepatic steatosis through SRBEP-1c activation. | 2015 | Details |
| A47109 | 25869468 | J Hepatobiliary Pancreat Sci | Recent advancement of molecular mechanisms of liver fibrosis. | 2015 | Details |
| A47112 | 25789959 | Medicine (Baltimore) | Changes in tumor necrosis factor-α, heat shock protein 70, malondialdehyde, and superoxide dismutase in patients with different severities of alcoholic fatty liver disease: a prospective observational study. | 2015 | Details |
| A47119 | 25595739 | Alcohol Alcohol | The role of lipin-1 in the pathogenesis of alcoholic fatty liver. | 2015 | Details |
| A47120 | 25592162 | Arch Biochem Biophys | Dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models. | 2015 | Details |
| A47123 | 25559494 | Alcohol | The effect of acute alcohol intoxication on gut wall integrity in healthy male volunteers; a randomized controlled trial. | 2014 | Details |
| A47133 | 25399514 | J Thromb Haemost | Protein S exacerbates alcoholic hepatitis by stimulating liver natural killer T cells. | 2014 | Details |
| A47147 | 24859453 | J Hepatol | Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury. | 2014 | Details |
| A47159 | 24722988 | J Biol Chem | Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol. | 2014 | Details |
| A47160 | 24713392 | Am J Pathol | M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease. | 2014 | Details |
| A47164 | 24513924 | Food Funct | Polyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice. | 2014 | Details |
| A47172 | 24262277 | Gastroenterology | Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver. | 2013 | Details |
| A47176 | 24155903 | PLoS One | Dietary zinc deficiency exaggerates ethanol-induced liver injury in mice: involvement of intrahepatic and extrahepatic factors. | 2013 | Details |
| A47177 | 24146112 | Arch Toxicol | Protective effects of dioscin against alcohol-induced liver injury. | 2013 | Details |
| A47181 | 24020403 | Int J Exp Pathol | Experimental rat model for alcohol-induced osteonecrosis of the femoral head. | 2013 | Details |
| A47187 | 23799218 | J Gastrointestin Liver Dis | Update on the management of alcoholic steatohepatitis. | 2013 | Details |
| A47195 | 23408358 | Hepatology | Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice. | 2013 | Details |
| A47196 | 23337955 | Int J Mol Med | Analysis of differentially expressed genes and microRNAs in alcoholic liver disease. | 2013 | Details |
| A47201 | 23025051 | Eksp Klin Farmakol | [Hepatoprotective and immunomodulatory effects of infliximab on experimental alcoholic steatohepatitis]. | 2012 | Details |
| A47207 | 22902304 | Gene | Genetic variants of TNFα, IL10, IL1β, CTLA4 and TGFβ1 modulate the indices of alcohol-induced liver injury in East Indian population. | 2012 | Details |
| A47208 | 22861370 | Clin Exp Immunol | Hepatic expression of CCL2 in alcoholic liver disease is associated with disease severity and neutrophil infiltrates. | 2012 | Details |
| A47213 | 22676331 | Alcohol Clin Exp Res | Thromboxane inhibitors attenuate inflammatory and fibrotic changes in rat liver despite continued ethanol administrations. | 2012 | Details |
| A47221 | 22425478 | Presse Med | [Current trends in liver biopsy indications in chronic liver diseases]. | 2012 | Details |
| A47226 | 22273278 | Alcohol Clin Exp Res | Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation. | 2012 | Details |
| A47228 | 22208561 | Lipids Health Dis | Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice. | 2011 | Details |
| A47230 | 22169690 | Zhonghua Yu Fang Yi Xue Za Zhi | [The effects of NF-E2-related factor-2 prompter polymorphism on alcoholic liver disease with Vibrio vulnificus sepsis]. | 2011 | Details |
| A47233 | 22013387 | J Biomed Biotechnol | Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feeding. | 2011 | Details |
| A47239 | 21790669 | Alcohol Clin Exp Res | Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis. | 2011 | Details |
| A47242 | 21673994 | PLoS One | Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model. | 2011 | Details |
| A47244 | 21645218 | Liver Int | Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts. | 2011 | Details |
| A47258 | 20955970 | Best Pract Res Clin Gastroenterol | Alcoholic steatohepatitis. | 2010 | Details |
| A47261 | 20399524 | J Hepatol | Harmful effect of adipose tissue on liver lesions in patients with alcoholic liver disease. | 2010 | Details |
| A47264 | 20171585 | J Chin Med Assoc | Serum interleukin-12 levels in alcoholic liver disease. | 2010 | Details |
| A47267 | 19958646 | Zhonghua Gan Zang Bing Za Zhi | [Magnesium isoglycyrrhizinate in the treatment of chronic liver diseases: a randomized, double-blind, multi-doses, active drug controlled, multi-center study]. | 2009 | Details |
| A47270 | 19696551 | Korean J Gastroenterol | [Sialadenosis in a patient with alcoholic fatty liver developing after heavy alcohol drinking]. | 2009 | Details |
| A47272 | 19645734 | Alcohol Clin Exp Res | Current experimental perspectives on the clinical progression of alcoholic liver disease. | 2009 | Details |
| A47278 | 19372631 | J Pharmacol Sci | Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c. | 2009 | Details |
| A47280 | 19285261 | Best Pract Res Clin Endocrinol Metab | The role of the endocannabinoid system in liver diseases. | 2009 | Details |
| A47300 | 18481025 | Arch Pharm Res | Effects of tanshinone IIA on the hepatotoxicity and gene expression involved in alcoholic liver disease. | 2008 | Details |
| A47301 | 18336673 | J Gastroenterol Hepatol | Cholesterol and sphingolipids in alcohol-induced liver injury. | 2008 | Details |
| A47302 | 18395093 | Gastroenterology | Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury. | 2008 | Details |
| A47304 | 18341647 | Alcohol Clin Exp Res | A voluntary oral ethanol-feeding rat model associated with necroinflammatory liver injury. | 2008 | Details |
| A47309 | 17850215 | Alcohol Clin Exp Res | Lysosomal leakage and lack of adaptation of hepatoprotective enzyme contribute to enhanced susceptibility to ethanol-induced liver injury in female rats. | 2007 | Details |
| A47315 | 17361525 | Chin J Integr Med | Intervention effects of Jianpi Liqi Huoxue Decoction on lipid peroxidative liver injury induced by alcohol. | 2006 | Details |
| A47319 | 17203086 | Nat Clin Pract Gastroenterol Hepatol | Management strategies in alcoholic liver disease. | 2007 | Details |
| A47329 | 16641879 | Med Sci Monit | Interleukin-8 in the blood serum of patients with alcoholic liver disease. | 2006 | Details |
| A47333 | 16439473 | Am J Physiol Gastrointest Liver Physiol | Involvement of Toll-like receptor 4 in acetaminophen hepatotoxicity. | 2006 | Details |
| A47336 | 16170395 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | High adiponectin and TNF-alpha levels in moderate drinkers suffering from liver steatosis: comparison with non drinkers suffering from similar hepatopathy. | 2005 | Details |
| A47337 | 16115302 | J Intern Med | Circulating adiponectin reflects severity of liver disease but not insulin sensitivity in liver cirrhosis. | 2005 | Details |
| A47345 | 15368449 | Hepatology | Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury. | 2004 | Details |
| A47352 | 14647036 | J Lab Clin Med | Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice. | 2003 | Details |
| A47360 | 12601343 | Hepatology | Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. | 2003 | Details |
| A47364 | 12388178 | Am J Physiol Gastrointest Liver Physiol | Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes. | 2002 | Details |
| A47368 | 11762137 | Pathol Biol (Paris) | Alcoholic liver injury: pathogenesis and therapy in 2001. | 2001 | Details |
| A47370 | 11343243 | Hepatology | Promoter polymorphism of the CD14 endotoxin receptor gene as a risk factor for alcoholic liver disease. | 2001 | Details |
| A47371 | 11320206 | Proc Natl Acad Sci U S A | Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. | 2001 | Details |
| A47373 | 11268819 | Am J Addict | Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment. | 2001 | Details |
| A47387 | 9665313 | Alcohol | Stimulation of monocyte interleukin-8 by lipid peroxidation products: a mechanism for alcohol-induced liver injury. | 1998 | Details |
| A47395 | 9438537 | Alcohol Clin Exp Res | Clinical significance of hepatitis GB virus C infection in alcoholic liver disease. | 1997 | Details |
| A47398 | 9309314 | Alcohol Clin Exp Res | Choline deficiency augments and antibody to tumor necrosis factor-alpha attenuates endotoxin-induced hepatic injury. | 1997 | Details |
| A47404 | 9195371 | J Gastroenterol Hepatol | Ethanol feeding enhances inflammatory cytokine expression in lipopolysaccharide-induced hepatitis. | 1997 | Details |
| A47407 | 8978360 | Gastroenterology | Thromboxane inhibitors attenuate pathological changes in alcoholic liver disease in the rat. | 1997 | Details |
| A47433 | 7865897 | Brain Behav Immun | Decreased beta-endorphin content in peripheral blood mononuclear leukocytes from patients with Crohn's disease. | 1994 | Details |
| A47456 | 8423034 | Hepatology | Experimental hepatitis induced by ethanol after immunization with acetaldehyde adducts. | 1993 | Details |
| A47464 | 1347281 | Gut | Is the intercellular adhesion molecule-1/leukocyte function associated antigen 1 pathway of leukocyte adhesion involved in the tissue damage of alcoholic hepatitis? | 1992 | Details |
| A47489 | 2774372 | Ann Intern Med | Is liver biopsy useful in the evaluation of patients with chronically elevated liver enzymes? | 1989 | Details |
| A47504 | 3183356 | J Hepatol | Is alcohol hepatotoxic in the baboon? | 1988 | Details |
| A47513 | 3655313 | J Hepatol | Alcohol-induced liver injury after jejunoileal bypass operation in rats. | 1987 | Details |
| A47516 | 3305847 | J Pathol | Endotoxin induced hepatic necrosis in rats on an alcohol diet. | 1987 | Details |
| A47518 | 3593004 | Arkh Patol | [Stellate reticuloendotheliocytes in cirrhosis of the liver]. | 1987 | Details |
| A47524 | 3490114 | Acta Pathol Microbiol Immunol Scand A | Phenotypic in situ characterization of lymphocytes in mild alcoholic liver disease. | 1986 | Details |
| A47588 | 6825980 | Gastroenterology | Alcoholic foamy degeneration--a pattern of acute alcoholic injury of the liver. | 1983 | Details |
| A47589 | 6832713 | Hepatology | Hepatic free fatty acids in alcoholic liver disease and morbid obesity. | 1983 | Details |
| A47599 | 7167038 | Liver | Intrahepatic synthesis of immunoglobulin in liver disease. | 1982 | Details |
| A47606 | 35195005 | J Med Chem | Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis. | 2022 | Details |
| A47613 | 35069833 | Exp Ther Med | Cardiovascular comorbidities in psoriasis (Review). | 2021 | Details |
| A47629 | 34750323 | Eur J Gastroenterol Hepatol | Prognostic value of neutrophil-to-lymphocyte ratio in cirrhosis patients undergoing transjugular intrahepatic portosystemic shunt. | 2022 | Details |
| A47634 | 34535788 | Nat Rev Drug Discov | Emerging therapeutic opportunities for integrin inhibitors. | 2021 | Details |
| A47651 | 34247393 | Aliment Pharmacol Ther | Systematic review with meta-analysis: The effects of non-steroidal anti-inflammatory drugs and anti-platelet therapy on the incidence and recurrence of hepatocellular carcinoma. | 2021 | Details |
| A47667 | 33976393 | Nat Rev Gastroenterol Hepatol | Regulation and functional roles of chemokines in liver diseases. | 2021 | Details |
| A47668 | 33962092 | J Nutr Biochem | Erratum to "Comprehensive characterization of metabolic, inflammatory and fibrotic changes in a mouse model of diet-derived nonalcoholic steatohepatitis" [The Journal of Nutritional Biochemistry Volume 85 (2020) 108463]. | 2021 | Details |
| A47673 | 33864004 | Cell Mol Immunol | Inflammatory processes in the liver: divergent roles in homeostasis and pathology. | 2021 | Details |