Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19484 | 26528818 | PLoS One | Evaluation of Transient Elastography, Acoustic Radiation Force Impulse Imaging (ARFI), and Enhanced Liver Function (ELF) Score for Detection of Fibrosis in Morbidly Obese Patients. | 2015 | Details |
| A19490 | 26524607 | Scand J Immunol | Effect of Lipopolysaccharide on the Progression of Non-Alcoholic Fatty Liver Disease in High Caloric Diet-Fed Mice. | 2016 | Details |
| A19495 | 26523205 | World J Hepatol | Dietary approach in the treatment of nonalcoholic fatty liver disease. | 2015 | Details |
| A19497 | 26522240 | Sci Rep | Cholesterol induces lipoprotein lipase expression in a tree shrew (Tupaia belangeri chinensis) model of non-alcoholic fatty liver disease. | 2015 | Details |
| A19499 | 26519296 | BMC Gastroenterol | Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown-Norway rats. | 2015 | Details |
| A19506 | 29083841 | Acta Med Croatica | [NON-ALCOHOLIC FATTY LIVER DISEASE]. | 2015 | Details |
| A19508 | 26516851 | Int J Mol Sci | Heat Killed Lactobacillus reuteri GMNL-263 Reduces Fibrosis Effects on the Liver and Heart in High Fat Diet-Hamsters via TGF-β Suppression. | 2015 | Details |
| A19515 | 26514735 | Dig Liver Dis | Cytokeratin 18-Aspartate396 apoptotic fragment for fibrosis detection in patients with non-alcoholic fatty liver disease and chronic viral hepatitis. | 2015 | Details |
| A19516 | 26514665 | J Gastroenterol Hepatol | Controlled attenuation parameter for the diagnosis of steatosis in non-alcoholic fatty liver disease. | 2016 | Details |
| A19517 | 26513612 | Eur J Gastroenterol Hepatol | Serum β-trophin level as a new marker for noninvasive assessment of nonalcoholic fatty liver disease and liver fibrosis. | 2016 | Details |
| A19520 | 26512661 | Int J Mol Sci | Non-Alcoholic Steatohepatitis (NASH): Risk Factors in Morbidly Obese Patients. | 2015 | Details |
| A19527 | 26509555 | Liver Int | Increasing aortic stiffness is predictive of advanced liver fibrosis in patients with type 2 diabetes: the Rio-T2DM cohort study. | 2015 | Details |
| A19531 | 26506944 | Biomark Med | Molecular regulation of miRNAs and potential biomarkers in the progression of hepatic steatosis to NASH. | 2015 | Details |
| A19533 | 26506376 | Nutrients | The Ethanol Extract from Lonicera japonica Thunb. Regresses Nonalcoholic Steatohepatitis in a Methionine- and Choline-Deficient Diet-Fed Animal Model. | 2015 | Details |
| A19537 | 26502898 | Chem Biol Drug Des | Synthesis of Naphthyl-, Quinolin- and Anthracenyl Analogues of Clofibric Acid as PPARα Agonists. | 2015 | Details |
| A19539 | 26500833 | Curr Hepatol Rep | Non-invasive Testing for NASH and NASH with Advanced Fibrosis: Are We There Yet? | 2015 | Details |
| A19543 | 26498332 | Lipids Health Dis | Resveratrol ameliorates hepatic steatosis and inflammation in methionine/choline-deficient diet-induced steatohepatitis through regulating autophagy. | 2015 | Details |
| A19547 | 26494963 | World J Gastroenterol | Liver fibrosis in non-alcoholic fatty liver disease - diagnostic challenge with prognostic significance. | 2015 | Details |
| A19548 | 26494962 | World J Gastroenterol | Endocrine causes of nonalcoholic fatty liver disease. | 2015 | Details |
| A19550 | 26494227 | Carcinogenesis | Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats. | 2015 | Details |
| A19554 | 26488474 | Dig Dis | Usefulness of Cytokeratin-18M65 in Diagnosing Non-Alcoholic Steatohepatitis in Japanese Population. | 2015 | Details |
| A19557 | 26486293 | Arq Gastroenterol | ACOUSTIC RADIATION FORCE IMPULSE IS EQUIVALENT TO LIVER BIOPSY TO EVALUATE LIVER FIBROSIS IN PATIENTS WITH CHRONIC HEPATITIS C AND NONALCOHOLIC FATTY LIVER DISEASE. | 2016 | Details |
| A19566 | 26482537 | J Lipid Res | SphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes. | 2015 | Details |
| A19581 | 26473614 | Hepatology | Peripheral insulin resistance predicts liver damage in nondiabetic subjects with nonalcoholic fatty liver disease. | 2015 | Details |
| A19585 | 26473136 | Pediatr Gastroenterol Hepatol Nutr | Low Serum Potassium Levels Associated with Disease Severity in Children with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19587 | 26472223 | Am J Physiol Gastrointest Liver Physiol | Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet. | 2015 | Details |
| A19588 | 26471505 | J Hepatol | Multiparametric magnetic resonance imaging predicts clinical outcomes in patients with chronic liver disease. | 2015 | Details |
| A19590 | 26469357 | Eur J Gastroenterol Hepatol | A novel model using mean platelet volume and neutrophil to lymphocyte ratio as a marker of nonalcoholic steatohepatitis in NAFLD patients: multicentric study. | 2016 | Details |
| A19591 | 26469309 | Expert Rev Gastroenterol Hepatol | Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis. | 2015 | Details |
| A19595 | 26464382 | J Mol Endocrinol | Glucose fluctuation increased hepatocyte apoptosis under lipotoxicity and the involvement of mitochondrial permeability transition opening. | 2015 | Details |
| A19598 | 26463593 | Genes Nutr | Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice. | 2015 | Details |
| A19599 | 26463349 | Crit Rev Clin Lab Sci | Omega-3 fatty acids: Mechanisms of benefit and therapeutic effects in pediatric and adult NAFLD. | 2015 | Details |
| A19602 | 26462489 | Dig Dis Sci | Poor Inter-test Reliability Between CK18 Kits as a Biomarker of NASH. | 2015 | Details |
| A19605 | 26461413 | Free Radic Biol Med | NASH (Nonalcoholic steatohepatitis): A case of multiorganelle failure. | 2014 | Details |
| A19611 | 26457389 | Hepatology | Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study. | 2015 | Details |
| A19619 | 26454513 | QJM | Clinically significant chronic liver disease in people with Type 2 diabetes: the Edinburgh Type 2 Diabetes Study. | 2015 | Details |
| A19623 | 26449892 | Nutr Clin Pract | Role of the Gut Microbiome in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19631 | 26447642 | J Child Adolesc Psychopharmacol | Nonalcoholic Fatty Liver Disease and Fibrosis in Youth Taking Psychotropic Medications: Literature Review, Case Reports, and Management. | 2015 | Details |
| A19632 | 26447219 | Am J Physiol Renal Physiol | NKT cell modulates NAFLD potentiation of metabolic oxidative stress-induced mesangial cell activation and proximal tubular toxicity. | 2015 | Details |
| A19635 | 26445592 | Nutr Metab (Lond) | Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1. | 2015 | Details |
| A19638 | 26444279 | Clin Exp Pharmacol Physiol | Increased ratio of neutrophil elastase to α1-antitrypsin is closely associated with liver inflammation in patients with nonalcoholic steatohepatitis. | 2016 | Details |
| A19643 | 26441244 | PLoS One | Hyperuricemia Inversely Correlates with Disease Severity in Taiwanese Nonalcoholic Steatohepatitis Patients. | 2015 | Details |
| A19650 | 26436447 | Liver Int | Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives. | 2015 | Details |
| A19654 | 26435078 | Metabolism | The role of bariatric surgery in the management of nonalcoholic fatty liver disease and metabolic syndrome. | 2015 | Details |
| A19659 | 26431876 | Biochem Biophys Res Commun | Hepatic scavenger receptor BI is associated with type 2 diabetes but unrelated to human and murine non-alcoholic fatty liver disease. | 2015 | Details |
| A19660 | 26430826 | J Am Coll Nutr | Effects of Multistrain Probiotic Supplementation on Glycemic and Inflammatory Indices in Patients with Nonalcoholic Fatty Liver Disease: A Double-Blind Randomized Clinical Trial. | 2015 | Details |
| A19664 | 26428254 | Obes Surg | Routine Liver Biopsy During Bariatric Surgery: an Analysis of Evidence Base. | 2016 | Details |
| A19669 | 26425466 | Indian J Endocrinol Metab | Profile of liver enzymes in non-alcoholic fatty liver disease in patients with impaired glucose tolerance and newly detected untreated type 2 diabetes. | 2015 | Details |
| A19678 | 28294798 | Kardiologiia | [Safety and Efficacy of Amlodipine, Lisinopril and Rosuvastatin Therapy in Patients With Metabolic Syndrome and Nonalcoholic Fatty Liver Disease]. | 2015 | Details |
| A19684 | 26412465 | Curr Pharm Des | Nonalcoholic fatty liver disease in children and adolescents - Relationship with Polycystic Ovary Syndrome. | 2015 | Details |
| A19685 | 26411937 | Nihon Eiseigaku Zasshi | [Mechanism Analysis and Prevention of Pathogenesis of Nonalcoholic Steatohepatitis]. | 2015 | Details |
| A19686 | 26410018 | Hum Pathol | Steatohepatitic variant of hepatocellular carcinoma in the absence of metabolic syndrome or background steatosis: a clinical, pathological, and genetic study. | 2015 | Details |
| A19687 | 26409295 | Metabolism | Genetics of nonalcoholic fatty liver disease. | 2015 | Details |
| A19693 | 26406351 | J Dig Dis | Nonalcoholic fatty liver disease - current status and future directions. | 2015 | Details |
| A19699 | 26405701 | J Gastrointestin Liver Dis | The Relationship of Serum Hemojuvelin and Hepcidin Levels with Iron Overload in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19701 | 26405614 | Cardiovasc Endocrinol | Relevance of low testosterone to non-alcoholic fatty liver disease. | 2015 | Details |
| A19705 | 26403427 | Dig Dis Sci | Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model. | 2015 | Details |
| A19717 | 26397061 | Mol Med Rep | Therapeutic effects of the dipeptidyl peptidase-IV inhibitor, sitagliptin, on non-alcoholic steatohepatitis in FLS-ob/ob male mice. | 2015 | Details |
| A19730 | 26390046 | Hepatology | Identification of novel noninvasive markers for diagnosing nonalcoholic steatohepatitis and related fibrosis by data mining. | 2015 | Details |
| A19731 | 26386476 | Ultrasound Med Biol | Liver Steatosis Assessed by Controlled Attenuation Parameter (CAP) Measured with the XL Probe of the FibroScan: A Pilot Study Assessing Diagnostic Accuracy. | 2015 | Details |
| A19740 | 26380042 | World J Hepatol | Targeting Kupffer cells in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Why and how? | 2015 | Details |
| A19745 | 26378648 | Semin Liver Dis | Pharmacotherapy for Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19748 | 26378645 | Semin Liver Dis | Noninvasive Evaluation of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19749 | 26378644 | Semin Liver Dis | The Genetics of Nonalcoholic Fatty Liver Disease: Spotlight on PNPLA3 and TM6SF2. | 2015 | Details |
| A19751 | 26378642 | Semin Liver Dis | Fatty Acid and Glucose Sensors in Hepatic Lipid Metabolism: Implications in NAFLD. | 2015 | Details |
| A19753 | 26378640 | Semin Liver Dis | Epidemiology and Natural History of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19762 | 26369383 | Aliment Pharmacol Ther | Non-invasive screening of diabetics in primary care for NAFLD and advanced fibrosis by MRI and MRE. | 2015 | Details |
| A19763 | 26367736 | Eur Rev Med Pharmacol Sci | Effect of silymarin plus vitamin E in patients with non-alcoholic fatty liver disease. A randomized clinical pilot study. | 2015 | Details |
| A19764 | 26367098 | Metab Syndr Relat Disord | Plasma Pentraxin 3 Differentiates Nonalcoholic Steatohepatitis (NASH) from Non-NASH. | 2015 | Details |
| A19774 | 26358367 | Sci Rep | Hyperinsulinemia shifted energy supply from glucose to ketone bodies in early nonalcoholic steatohepatitis from high-fat high-sucrose diet induced Bama minipigs. | 2015 | Details |
| A19786 | 26349582 | Ultrasound Med Biol | Shear Wave Elastography for Assessment of Steatohepatitis and Hepatic Fibrosis in Rat Models of Non-Alcoholic Fatty Liver Disease. | 2015 | Details |
| A19787 | 26349165 | Trop Gastroenterol | Nonalcoholic Fatty Liver Disease--The Clinician's Perspective. | 2015 | Details |
| A19800 | 26341864 | Indian J Gastroenterol | Simple biochemical parameters and a novel score correlate with absence of fibrosis in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A19805 | 26339640 | Biomed Res Int | The Role of Dendritic Cells in Fibrosis Progression in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19807 | 26338827 | Gut | Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression. | 2015 | Details |
| A19810 | 26335400 | Redox Biol | Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences. | 2015 | Details |
| A19814 | 26330688 | Trans Am Clin Climatol Assoc | A Lipidomic Readout of Disease Progression in A Diet-Induced Mouse Model of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19815 | 26330344 | Am J Physiol Endocrinol Metab | Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism. | 2015 | Details |
| A19819 | 26328027 | World J Hepatol | Advances in hepatocellular carcinoma: Nonalcoholic steatohepatitis-related hepatocellular carcinoma. | 2015 | Details |
| A19820 | 26328025 | World J Hepatol | From the stomach to other organs: Helicobacter pylori and the liver. | 2015 | Details |
| A19827 | 26322888 | PLoS One | Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19830 | 26319415 | Biochim Biophys Acta | TRC8 downregulation contributes to the development of non-alcoholic steatohepatitis by exacerbating hepatic endoplasmic reticulum stress. | 2015 | Details |
| A19839 | 26315777 | Ann Nutr Metab | Association between Serum Sialic Acid Levels and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study. | 2015 | Details |
| A19840 | 26315331 | Diabet Med | Diabetic hepatosclerosis: another diabetes microvascular complication? | 2016 | Details |
| A19841 | 26315048 | J Lipid Res | Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway. | 2015 | Details |
| A19842 | 26314837 | J Gastroenterol | Prevalence of nonalcoholic steatohepatitis in Japanese patients with morbid obesity undergoing bariatric surgery. | 2015 | Details |
| A19843 | 26314479 | Eur Radiol | Magnetic resonance elastography for staging liver fibrosis in non-alcoholic fatty liver disease: a diagnostic accuracy systematic review and individual participant data pooled analysis. | 2015 | Details |
| A19856 | 26303130 | Am J Gastroenterol | Cost-Effective Evaluation of Nonalcoholic Fatty Liver Disease With NAFLD Fibrosis Score and Vibration Controlled Transient Elastography. | 2015 | Details |
| A19858 | 26302023 | Eur J Gastroenterol Hepatol | Comparative diagnostic accuracy of red cell distribution width-to-platelet ratio versus noninvasive fibrosis scores for the diagnosis of liver fibrosis in biopsy-proven nonalcoholic fatty liver disease. | 2015 | Details |
| A19861 | 26300318 | Mol Nutr Food Res | Nonalcoholic fatty liver disease: Roles of the gut and the liver and metabolic modulation by some dietary factors and especially long-chain n-3 PUFA. | 2015 | Details |
| A19864 | 26299412 | Gastroenterology | Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. | 2015 | Details |
| A19868 | 26297218 | J Diabetes Complications | An association of large-fibre peripheral nerve dysfunction with non-invasive measures of liver fibrosis secondary to non-alcoholic fatty liver disease in diabetes. | 2015 | Details |
| A19870 | 26293833 | Eur J Intern Med | Increased circulating adiponectin in males with chronic HCV hepatitis. | 2015 | Details |
| A19872 | 26292849 | Br J Pharmacol | Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes. | 2015 | Details |
| A19875 | 26290633 | World J Gastroenterol | Female spontaneously diabetic Torii fatty rats develop nonalcoholic steatohepatitis-like hepatic lesions. | 2015 | Details |
| A19877 | 26289793 | Sci Rep | Characterization of hepatic lipid profiles in a mouse model with nonalcoholic steatohepatitis and subsequent fibrosis. | 2015 | Details |
| A19878 | 26289505 | Niger J Clin Pract | Nonalcoholic fatty liver disease: Synopsis of current developments. | 2016 | Details |
| A19886 | 26283807 | Anc Sci Life | Efficacy of herbomineral compounds and pathya (Ayurvedic dietary regime and physical exercise) in the management of Yakṛt Roga (Non-alcoholic fatty liver disease). | 2015 | Details |
| A19889 | 26282529 | Proc Nutr Soc | Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr-/- mice. | 2015 | Details |
| A19891 | 26281317 | Turk J Med Sci | Effect of pioglitazone, quercetin, and hydroxy citric acid on vascular endothelial growth factor messenger RNA (VEGF mRNA) expression in experimentally induced nonalcoholic steatohepatitis (NASH). | 2015 | Details |