Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19899 | 26278387 | Curr Mol Pharmacol | Review: Precision Cut Liver Slices for the Evaluation of Fatty Liver and Fibrosis. | 2017 | Details |
| A19904 | 26273651 | Biomed Res Int | Nonalcoholic Steatohepatitis: Involvement of the Telomerase and Proinflammatory Mediators. | 2015 | Details |
| A19906 | 26273620 | Biomed Res Int | Improvement of BMI after Lifestyle Intervention Is Associated with Normalisation of Elevated ELF Score and Liver Stiffness in Obese Children. | 2015 | Details |
| A19915 | 26270240 | J Gastroenterol Hepatol | Acetylcholine induces fibrogenic effects via M2/M3 acetylcholine receptors in non-alcoholic steatohepatitis and in primary human hepatic stellate cells. | 2016 | Details |
| A19924 | 26263022 | Sci Rep | Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis. | 2015 | Details |
| A19929 | 26259026 | Liver Int | TM6SF2 rs58542926 is not associated with steatosis and fibrosis in large cohort of patients with genotype 1 chronic hepatitis C. | 2015 | Details |
| A19939 | 26253086 | Clin Sci (Lond) | CX3CR1-expressing inflammatory dendritic cells contribute to the progression of steatohepatitis. | 2015 | Details |
| A19945 | 26250831 | Dig Dis Sci | Hepatocellular Carcinoma in the Setting of Non-cirrhotic Nonalcoholic Fatty Liver Disease and the Metabolic Syndrome: US Experience. | 2015 | Details |
| A19947 | 26250514 | Obesity (Silver Spring) | Exercise improves adipose function and inflammation and ameliorates fatty liver disease in obese diabetic mice. | 2015 | Details |
| A19955 | 26242257 | Curr Med Chem | Flavonoids and Related Compounds in Non-Alcoholic Fatty Liver Disease Therapy. | 2015 | Details |
| A19957 | 26241028 | J Steroid Biochem Mol Biol | Glucocorticoids and non-alcoholic fatty liver disease. | 2015 | Details |
| A19970 | 26233911 | Adv Pharmacol | Translational Implications of the Alcohol-Metabolizing Enzymes, Including Cytochrome P450-2E1, in Alcoholic and Nonalcoholic Liver Disease. | 2015 | Details |
| A19974 | 26231377 | Drug Metab Dispos | CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19976 | 26229402 | World J Gastroenterol | Linked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B. | 2015 | Details |
| A19984 | 26226097 | Clin Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease Review: Diagnosis, Treatment, and Outcomes. | 2015 | Details |
| A19985 | 26226095 | Clin Gastroenterol Hepatol | Incorporation of Noninvasive Measures of Liver Fibrosis Into Clinical Practice: Diagnosis and Prognosis. | 2015 | Details |
| A19992 | 26219858 | Mayo Clin Proc | Recommendations for Diagnosis, Referral for Liver Biopsy, and Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2015 | Details |
| A19993 | 26219393 | Curr Med Chem | The Pros and the Cons for the Use of Silybin-Rich Oral Formulations in Treatment of Liver Damage (NAFLD in Particular). | 2015 | Details |
| A19995 | 26216030 | Clin Res Hepatol Gastroenterol | Inflammasome activation in the liver: Focus on alcoholic and non-alcoholic steatohepatitis. | 2015 | Details |
| A19997 | 26215532 | Am J Gastroenterol | Prevalence and Severity of Nonalcoholic Fatty Liver Disease in Non-Obese Patients: A Population Study Using Proton-Magnetic Resonance Spectroscopy. | 2015 | Details |
| A20004 | 26214582 | Lab Invest | Pivotal role of liver sinusoidal endothelial cells in NAFLD/NASH progression. | 2015 | Details |
| A20013 | 26204635 | Rev Med Chir Soc Med Nat Iasi | NONALCOHOLIC FATTY LIVER DISEASE AND ITS COMPLICATIONS--ASSESSING THE POPULATION AT RISK. A SMALL SERIES REPORT AND LITERATURE REVIEW. | 2015 | Details |
| A20018 | 26202818 | Aliment Pharmacol Ther | Bacterial endotoxin and non-alcoholic fatty liver disease in the general population: a prospective cohort study. | 2015 | Details |
| A20021 | 26202098 | Cardiovasc Ther | Nonalcoholic Steatohepatitis Score is an Independent Predictor of Right Ventricular Dysfunction in Patients with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20022 | 26201937 | Clin Endocrinol (Oxf) | Nonalcoholic fatty pancreas disease and Nonalcoholic fatty liver disease: more than ectopic fat. | 2015 | Details |
| A20023 | 26201461 | Drugs | Non-Alcoholic Steatohepatitis: Limited Available Treatment Options but Promising Drugs in Development and Recent Progress Towards a Regulatory Approval Pathway. | 2015 | Details |
| A20025 | 26201023 | Clin Sci (Lond) | Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis. | 2015 | Details |
| A20031 | 26199205 | Hepatology | A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers. | 2015 | Details |
| A20037 | 26196445 | Clin Gastroenterol Hepatol | Hepatocellular Carcinoma in the Absence of Cirrhosis in United States Veterans is Associated With Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20039 | 26194602 | Liver Transpl | Serum fibrosis biomarkers predict death and graft loss in liver transplantation recipients. | 2015 | Details |
| A20045 | 26193051 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease-related cardiovascular risk: Is there an association with blood hemoglobin levels? | 2015 | Details |
| A20052 | 26190322 | Hepatol Res | Chronic hepatitis without hepatic steatosis caused by citrin deficiency in a child. | 2015 | Details |
| A20054 | 26189985 | Clin Res Hepatol Gastroenterol | Synergy between NAFLD and AFLD and potential biomarkers. | 2015 | Details |
| A20055 | 26189925 | Hepatology | Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta-analysis. | 2015 | Details |
| A20062 | 26185381 | World J Gastroenterol | Increased serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with biopsy-proven nonalcoholic fatty liver disease. | 2015 | Details |
| A20064 | 26183212 | Dis Model Mech | Ovarian senescence increases liver fibrosis in humans and zebrafish with steatosis. | 2015 | Details |
| A20065 | 26182253 | Dtsch Med Wochenschr | [Non-alcoholic fatty liver disease (NAFLD)]. | 2015 | Details |
| A20078 | 26170532 | Mediators Inflamm | LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20091 | 26160475 | Clin Res Hepatol Gastroenterol | Genetic polymorphisms and oxidative stress in non-alcoholic steatohepatitis (NASH): A mini review. | 2015 | Details |
| A20094 | 26159280 | Dig Dis | Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH. | 2015 | Details |
| A20101 | 26155039 | J Clin Exp Hepatol | Rapid Reversal of Liver Steatosis With Life Style Modification in Highly Motivated Liver Donors. | 2015 | Details |
| A20106 | 26151226 | Clin Biochem | Gut-liver axis, nutrition, and non-alcoholic fatty liver disease. | 2015 | Details |
| A20125 | 26139988 | World J Gastroenterol | Liver fibrosis markers of nonalcoholic steatohepatitis. | 2015 | Details |
| A20127 | 26138749 | Expert Rev Gastroenterol Hepatol | In search of the magic bullet: can liver inflammation and fibrosis be reversed with medications? | 2015 | Details |
| A20138 | 26133299 | Eur J Nutr | Bee's honey attenuates non-alcoholic steatohepatitis-induced hepatic injury through the regulation of thioredoxin-interacting protein-NLRP3 inflammasome pathway. | 2015 | Details |
| A20142 | 26131717 | PLoS One | Acoustic Radiation Force Impulse Elastography for the Non-Invasive Evaluation of Hepatic Fibrosis in Non-Alcoholic Fatty Liver Disease Patients: A Systematic Review & Meta-Analysis. | 2015 | Details |
| A20146 | 26124760 | Front Immunol | Role of Macrophage Migration Inhibitory Factor in Obesity, Insulin Resistance, Type 2 Diabetes, and Associated Hepatic Co-Morbidities: A Comprehensive Review of Human and Rodent Studies. | 2015 | Details |
| A20147 | 26124313 | J Clin Pathol | Portal inflammation during NAFLD is frequent and associated with the early phases of putative hepatic progenitor cell activation. | 2015 | Details |
| A20154 | 26120584 | Biomed Res Int | The Dual Role of Nrf2 in Nonalcoholic Fatty Liver Disease: Regulation of Antioxidant Defenses and Hepatic Lipid Metabolism. | 2015 | Details |
| A20155 | 26119353 | Aliment Pharmacol Ther | Novel association between serum pentraxin-2 levels and advanced fibrosis in well-characterised patients with non-alcoholic fatty liver disease. | 2015 | Details |
| A20160 | 26116591 | Ann Clin Lab Sci | Neutrophil-Lymphocyte Ratio (NLR) Could Be Better Predictor than C-reactive Protein (CRP) for Liver Fibrosis in Non-alcoholic Steatohepatitis(NASH). | 2015 | Details |
| A20168 | 26114083 | Curr Hepatol Rep | PATHOGENESIS OF HEPATOCELLULAR CARCINOMA DEVELOPMENT IN NON ALCOHOLIC FATTY LIVER DISEASE. | 2015 | Details |
| A20173 | 26112094 | Exp Mol Pathol | Fat-laden macrophages modulate lobular inflammation in nonalcoholic steatohepatitis (NASH). | 2015 | Details |
| A20174 | 26111358 | J Gastroenterol Hepatol | Incretin-based therapies for the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2016 | Details |
| A20177 | 26108652 | Indian J Gastroenterol | Serum ferritin levels predict histological severity in patients with nonalcoholic fatty liver disease in India. | 2015 | Details |
| A20186 | 26098879 | PLoS One | Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet. | 2015 | Details |
| A20204 | 26085906 | World J Hepatol | Non-alcoholic fatty liver disease in 2015. | 2015 | Details |
| A20206 | 26085300 | Sleep | Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea. | 2015 | Details |
| A20208 | 26083565 | PLoS One | Prognostic Value of Non-Invasive Fibrosis and Steatosis Tools, Hepatic Venous Pressure Gradient (HVPG) and Histology in Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20219 | 26078579 | World J Gastroenterol | Efficacy of poly-unsaturated fatty acid therapy on patients with nonalcoholic steatohepatitis. | 2015 | Details |
| A20221 | 26078558 | World J Gastroenterol | Cardiovascular risk across the histological spectrum and the clinical manifestations of non-alcoholic fatty liver disease: An update. | 2015 | Details |
| A20226 | 26077701 | Surg Obes Relat Dis | Effect of Roux-en-Y gastric bypass and sleeve gastrectomy on nonalcoholic fatty liver disease: a comparative study. | 2015 | Details |
| A20227 | 26077675 | J Transl Med | Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice. | 2015 | Details |
| A20231 | 26076224 | Can J Gastroenterol Hepatol | Nonmedicinal interventions in nonalcoholic fatty liver disease. | 2016 | Details |
| A20232 | 26074683 | World J Gastroenterol | Controversy in the diagnosis of pediatric non-alcoholic fatty liver disease. | 2015 | Details |
| A20233 | 26073454 | Prog Lipid Res | Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research. | 2015 | Details |
| A20238 | 26070409 | J Hepatol | Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease. | 2015 | Details |
| A20240 | 26069285 | Thorax | Altered gut-liver axis and hepatic adiponectin expression in OSAS: novel mediators of liver injury in paediatric non-alcoholic fatty liver. | 2015 | Details |
| A20245 | 26064924 | Biomed Res Int | Nonalcoholic Steatohepatitis: A Search for Factual Animal Models. | 2015 | Details |
| A20248 | 26064294 | Int J Clin Exp Med | Association between vitamin E and non-alcoholic steatohepatitis: a meta-analysis. | 2015 | Details |
| A20249 | 26064107 | Int J Endocrinol | Noninvasive Assessment of Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20252 | 26062958 | Acta Derm Venereol | Increased Prevalence of Advanced Liver Fibrosis in Patients with Psoriasis: A Cross-sectional Analysis from the Rotterdam Study. | 2016 | Details |
| A20254 | 26062078 | Eur J Gastroenterol Hepatol | Neutrophil-to-lymphocyte ratio is not a predictor of liver histology in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20258 | 26059365 | Nutrition | Vitamin E has a beneficial effect on nonalcoholic fatty liver disease: a meta-analysis of randomized controlled trials. | 2014 | Details |
| A20260 | 26058518 | Antioxid Redox Signal | Myeloperoxidase-Hepatocyte-Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20261 | 26058319 | Liver Int | Transient elastography and aspartate aminotransferase to platelet ratio predict liver injury in paediatric intestinal failure. | 2015 | Details |
| A20262 | 26057287 | JAMA | Nonalcoholic fatty liver disease: a systematic review. | 2015 | Details |
| A20271 | 26052378 | World J Hepatol | Oxidative stress: New insights on the association of non-alcoholic fatty liver disease and atherosclerosis. | 2015 | Details |
| A20272 | 26052375 | World J Hepatol | Pathophysiological mechanisms involved in non-alcoholic steatohepatitis and novel potential therapeutic targets. | 2015 | Details |
| A20273 | 26051274 | Biochem Biophys Res Commun | Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells. | 2015 | Details |
| A20275 | 26049712 | Eur J Gastroenterol Hepatol | Diagnostic usefulness of FibroMeter VCTE for hepatic fibrosis in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20276 | 26049707 | Eur J Gastroenterol Hepatol | Noninvasive estimation of disease activity and liver fibrosis in nonalcoholic fatty liver disease using anthropometric and biochemical characteristics, including insulin, insulin resistance, and 13C-methionine breath test. | 2015 | Details |
| A20277 | 26049666 | Clin Investig Arterioscler | [Role of metabolic lipases and lipotoxicity in the development of non-alcoholic steatosis and non-alcoholic steatohepatitis]. | 2015 | Details |
| A20298 | 26040357 | Nutr Hosp | Predictive factors of non-alcoholic steatohepatitis: relationship with metabolic syndrome. | 2015 | Details |
| A20313 | 26033743 | J Nutr Biochem | Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease. | 2015 | Details |
| A20318 | 26031832 | Curr Gastroenterol Rep | A comprehensive review of noninvasive liver fibrosis tests in pediatric nonalcoholic Fatty liver disease. | 2015 | Details |
| A20320 | 26031147 | Klin Med (Mosk) | [Metabolic disorder and polymorphism of the genes encoding for beta-2-adrenergic receptor and apolipoproteins B in chronic hepatitis C and non-alcoholic fatty liver diseases]. | 2015 | Details |
| A20322 | 26028579 | Gastroenterology | Association of Adipose Tissue Inflammation With Histologic Severity of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20327 | 26027904 | Biochim Biophys Acta | Recent insights on the role of cholesterol in non-alcoholic fatty liver disease. | 2015 | Details |
| A20330 | 26026390 | Gastroenterology | High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery. | 2015 | Details |
| A20335 | 26024975 | Endocrine | Evidence that non-alcoholic fatty liver disease and polycystic ovary syndrome are associated by necessity rather than chance: a novel hepato-ovarian axis? | 2015 | Details |
| A20340 | 26021772 | Saudi J Gastroenterol | The relationship of circulating fetuin-a with liver histology and biomarkers of systemic inflammation in nondiabetic subjects with nonalcoholic fatty liver disease. | 2016 | Details |
| A20342 | 26020857 | Nanomedicine (Lond) | Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis. | 2015 | Details |
| A20346 | 26019735 | World J Hepatol | Composite prognostic models across the non-alcoholic fatty liver disease spectrum: Clinical application in developing countries. | 2015 | Details |
| A20348 | 26019451 | World J Gastroenterol | Effect of nuclear factor-κB and angiotensin II receptor type 1 on the pathogenesis of rat non-alcoholic fatty liver disease. | 2015 | Details |
| A20355 | 26018806 | Mol Med | Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20358 | 26017539 | PLoS One | Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease. | 2015 | Details |
| A20363 | 26016461 | Hepatol Int | Pattern and profile of chronic liver disease in acute on chronic liver failure. | 2015 | Details |
| A20365 | 26013469 | J Nutr Biochem | Platelet-activating factor modulates fat storage in the liver induced by a high-refined carbohydrate-containing diet. | 2015 | Details |
| A20367 | 26011302 | Metab Syndr Relat Disord | Insulin Resistance but Not Visceral Adiposity Index Is Associated with Liver Fibrosis in Nondiabetic Subjects with Nonalcoholic Fatty Liver Disease. | 2015 | Details |