Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A21597 | 25195550 | J Hepatol | Incidence of non-alcoholic fatty liver disease in Hong Kong: a population study with paired proton-magnetic resonance spectroscopy. | 2014 | Details |
A21599 | 25195547 | J Hepatol | Effects of n-3 fish oil on metabolic and histological parameters in NASH: a double-blind, randomized, placebo-controlled trial. | 2014 | Details |
A21602 | 25194181 | Best Pract Res Clin Gastroenterol | Non-alcoholic fatty liver disease, obesity and the metabolic syndrome. | 2014 | Details |
A21608 | 25190263 | Dig Dis Sci | Gaps in recognition and evaluation of incidentally identified hepatic steatosis. | 2014 | Details |
A21613 | 25186086 | Aliment Pharmacol Ther | Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia. | 2014 | Details |
A21618 | 25183341 | Trends Endocrinol Metab | Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD. | 2014 | Details |
A21628 | 25170559 | Digestion | Can serum pin1 level be regarded as an indicative marker of nonalcoholic steatohepatitis and fibrotic stages? | 2014 | Details |
A21630 | 25168691 | J Gastroenterol Hepatol | Use of non-invasive serum glycan markers to distinguish non-alcoholic steatohepatitis from simple steatosis. | 2015 | Details |
A21633 | 25165040 | Hepatol Res | Predictors of malignancies and overall mortality in Japanese patients with biopsy-proven non-alcoholic fatty liver disease. | 2014 | Details |
A21640 | 25163357 | Hepatol Res | Lower levels of insulin-like growth factor-1 standard deviation score are associated with histological severity of non-alcoholic fatty liver disease. | 2014 | Details |
A21644 | 25156535 | Mol Biol Rep | HLA DQB1 alleles are related with nonalcoholic fatty liver disease. | 2014 | Details |
A21652 | 25152587 | World J Gastroenterol | Noninvasive biomarkers in non-alcoholic fatty liver disease: current status and a glimpse of the future. | 2014 | Details |
A21655 | 25145976 | Hepatol Res | Non-alcoholic fatty liver disease fibrosis score and FIB-4 scoring system could identify patients at risk of systemic complications. | 2014 | Details |
A21656 | 25145655 | Toxicol Sci | Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat. | 2014 | Details |
A21657 | 25145475 | Hepatology | The role of liver fat and insulin resistance as determinants of plasma aminotransferase elevation in nonalcoholic fatty liver disease. | 2014 | Details |
A21671 | 25134788 | Gut | Vitamin D counteracts fibrogenic TGF-β signalling in human hepatic stellate cells both receptor-dependently and independently. | 2014 | Details |
A21677 | 25126490 | Springerplus | Non-high-density lipoprotein cholesterol (non-HDL-C) levels in children with nonalcoholic fatty liver disease (NAFLD). | 2014 | Details |
A21678 | 25126183 | Int J Clin Exp Med | Serum endocan levels in patients with chronic liver disease. | 2014 | Details |
A21681 | 25125077 | Hepatology | Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. | 2015 | Details |
A21683 | 25122558 | FASEB J | Protective role of macrophage migration inhibitory factor in nonalcoholic steatohepatitis. | 2014 | Details |
A21684 | 25121996 | Endocrinology | Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism. | 2014 | Details |
A21685 | 25121514 | PLoS One | The development of the pediatric NAFLD fibrosis score (PNFS) to predict the presence of advanced fibrosis in children with nonalcoholic fatty liver disease. | 2014 | Details |
A21694 | 25114474 | Indian J Surg Oncol | Steatohepatitic hepatocellular carcinoma-a case report with literature review. | 2014 | Details |
A21695 | 25112833 | J Endocrinol | Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet. | 2014 | Details |
A21696 | 25111713 | PLoS One | Association between noninvasive fibrosis markers and cardio-vascular organ damage among adults with hepatic steatosis. | 2014 | Details |
A21700 | 25110437 | World J Gastroenterol | Simple scoring system for predicting cirrhosis in nonalcoholic fatty liver disease. | 2014 | Details |
A21708 | 25103310 | Hepatology | Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. | 2014 | Details |
A21709 | 25102981 | Dig Dis Sci | Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease. | 2014 | Details |
A21719 | 25093717 | Int J Mol Sci | Cystic fibrosis related liver disease--another black box in hepatology. | 2014 | Details |
A21727 | 25088269 | Curr Pediatr Rev | Nonalcoholic fatty liver disease in children: recent practice guidelines, where do they take us? | 2014 | Details |
A21733 | 25083607 | Gastroenterology | Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets. | 2014 | Details |
A21734 | 25083081 | World J Gastroenterol | Potential roles of glucagon-like peptide-1-based therapies in treating non-alcoholic fatty liver disease. | 2014 | Details |
A21735 | 25083080 | World J Gastroenterol | Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the liver disease of our age? | 2014 | Details |
A21738 | 25083077 | World J Gastroenterol | Translational approaches: from fatty liver to non-alcoholic steatohepatitis. | 2014 | Details |
A21739 | 25083076 | World J Gastroenterol | Role of liver biopsy in nonalcoholic fatty liver disease. | 2014 | Details |
A21746 | 25073966 | Pediatr Obes | The macrophage activation marker sCD163 is associated with changes in NAFLD and metabolic profile during lifestyle intervention in obese children. | 2014 | Details |
A21747 | 25073669 | Korean J Gastroenterol | [Comparison on the efficacy and safety of biphenyl dimethyl dicarboxylate and ursodeoxycholic acid in patients with abnormal alanine aminotransferase: multicenter, double-blinded, randomized, active-controlled clinical trial]. | 2014 | Details |
A21756 | 25069572 | Dig Dis Sci | Role of the PNPLA3 I148M polymorphism in nonalcoholic fatty liver disease and fibrosis in Korea. | 2014 | Details |
A21757 | 25068001 | World J Hepatol | CEUS and Fibroscan in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. | 2014 | Details |
A21768 | 25060399 | J Dig Dis | Progression of liver disease in non-alcoholic fatty liver disease: a prospective clinicopathological follow-up study. | 2014 | Details |
A21769 | 25060337 | Sci Rep | Association between serum free fatty acid levels and nonalcoholic fatty liver disease: a cross-sectional study. | 2014 | Details |
A21774 | 25053716 | Gut | Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis. | 2014 | Details |
A21779 | 25050550 | PLoS Med | Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis. | 2014 | Details |
A21780 | 25048953 | J Hepatol | Cyclophilin inhibition as potential therapy for liver diseases. | 2014 | Details |
A21785 | 25045618 | Curr Hepatol Rep | Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis. | 2014 | Details |
A21787 | 25045276 | Clin Exp Gastroenterol | Molecular pathways in non-alcoholic fatty liver disease. | 2014 | Details |
A21791 | 25043514 | Hepatology | Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: results from the Welcome* study. | 2014 | Details |
A21794 | 25040931 | Hepatol Res | Measurement of liver stiffness as a non-invasive method for diagnosis of non-alcoholic fatty liver disease. | 2014 | Details |
A21796 | 25040043 | Liver Int | microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis. | 2014 | Details |
A21797 | 25039333 | J Gastroenterol Hepatol | Single non-invasive model to diagnose non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). | 2014 | Details |
A21803 | 25034292 | Dig Dis | Non-alcoholic fatty liver disease: diagnosis and investigation. | 2014 | Details |
A21805 | 25034283 | Dig Dis | The inflammasome in liver injury and non-alcoholic fatty liver disease. | 2014 | Details |
A21814 | 25028077 | Transl Res | Obesity and the liver: nonalcoholic fatty liver disease. | 2014 | Details |
A21817 | 25024607 | World J Gastroenterol | High fat diet feeding results in gender specific steatohepatitis and inflammasome activation. | 2014 | Details |
A21820 | 25024596 | World J Gastroenterol | Non-alcoholic fatty liver disease and diabetes: from physiopathological interplay to diagnosis and treatment. | 2014 | Details |
A21821 | 25024595 | World J Gastroenterol | Experimental models of non-alcoholic fatty liver disease in rats. | 2014 | Details |
A21824 | 25024592 | World J Gastroenterol | Proteomic and genomic studies of non-alcoholic fatty liver disease--clues in the pathogenesis. | 2014 | Details |
A21826 | 25023045 | Indian J Gastroenterol | Clinical, anthropometric, biochemical, and histological characteristics of nonobese nonalcoholic fatty liver disease patients of Bangladesh. | 2014 | Details |
A21827 | 25019921 | Dtsch Arztebl Int | Non-alcoholic fatty liver disease: epidemiology, clinical course, investigation, and treatment. | 2014 | Details |
A21830 | 25018867 | Frontline Gastroenterol | Non-alcoholic fatty liver disease: a practical approach to diagnosis and staging. | 2013 | Details |
A21838 | 25011936 | Gut | Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease. | 2014 | Details |
A21839 | 25009583 | Exp Ther Med | Evaluation of fatty liver fibrosis in rabbits using real-time shear wave elastography. | 2014 | Details |
A21844 | 25004910 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | The prevalence of nonalcoholic liver steatosis in patients with type 2 diabetes mellitus in the Czech Republic. | 2014 | Details |
A21851 | 25002154 | Gastroenterol Rep (Oxf) | Simple non-invasive biomarkers of advanced fibrosis in the evaluation of non-alcoholic fatty liver disease. | 2014 | Details |
A21854 | 24998389 | Sci Rep | Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model. | 2014 | Details |
A21857 | 24995693 | Hepatology | The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice. | 2014 | Details |
A21876 | 24986741 | J Transl Med | Progression of diet induced nonalcoholic steatohepatitis is accompanied by increased expression of Kruppel-like-factor 10 in mice. | 2014 | Details |
A21879 | 24983359 | PLoS One | L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway. | 2014 | Details |
A21880 | 24983336 | Med Sci Sports Exerc | Treating NAFLD in OLETF rats with vigorous-intensity interval exercise training. | 2015 | Details |
A21882 | 24978903 | Nat Commun | TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease. | 2014 | Details |
A21884 | 24978432 | Cancers (Basel) | Fibrogenesis and Carcinogenesis in Nonalcoholic Steatohepatitis (NASH): Involvement of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinase (TIMPs). | 2014 | Details |
A21885 | 24977111 | Curr Hepatol Rep | Hepatic steatosis and steatohepatitis: Are they really two distinct entities? | 2014 | Details |
A21889 | 24976563 | Hepatol Res | Influence of lifestyle-related diseases and age on the development and progression of non-alcoholic fatty liver disease. | 2014 | Details |
A21891 | 24976401 | Biochem Biophys Res Commun | NHE1 deficiency in liver: implications for non-alcoholic fatty liver disease. | 2014 | Details |
A21898 | 24974878 | Ann Gastroenterol | Insulin resistance in euglycemic cirrhosis. | 2014 | Details |
A21909 | 24968200 | Br J Nutr | Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of type 2 diabetes and non-alcoholic fatty liver disease in high-fructose diet-fed rats. | 2014 | Details |
A21911 | 24966609 | World J Gastroenterol | Radiologic evaluation of nonalcoholic fatty liver disease. | 2014 | Details |
A21915 | 24966605 | World J Gastroenterol | Pediatric fatty liver disease: role of ethnicity and genetics. | 2014 | Details |
A21919 | 24966597 | World J Gastroenterol | Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update. | 2014 | Details |
A21920 | 24966582 | World J Gastroenterol | Pathogenesis and significance of hepatitis C virus steatosis: an update on survival strategy of a successful pathogen. | 2014 | Details |
A21923 | 24963148 | EMBO Mol Med | A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis. | 2014 | Details |
A21927 | 24961607 | Liver Transpl | Recurrent or de novo nonalcoholic fatty liver disease after liver transplantation: natural history based on liver biopsy analysis. | 2014 | Details |
A21937 | 24952996 | Neurogastroenterol Motil | Damage to enteric neurons occurs in mice that develop fatty liver disease but not diabetes in response to a high-fat diet. | 2014 | Details |
A21938 | 24952382 | Lipids Health Dis | Nonalcoholic steatohepatitis is associated with an atherogenic lipoprotein subfraction profile. | 2014 | Details |
A21947 | 24946279 | J Hepatol | ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis. | 2014 | Details |
A21950 | 24944472 | World J Gastroenterol | Bedside ultrasound in the diagnosis of nonalcoholic fatty liver disease. | 2014 | Details |
A21951 | 24943967 | Eur Rev Med Pharmacol Sci | High sensitive CRP and pentraxine 3 as noninvasive biomarkers of nonalcoholic fatty liver disease. | 2014 | Details |
A21952 | 24941342 | Molecules | Standardized Salvia miltiorrhiza extract suppresses hepatic stellate cell activation and attenuates steatohepatitis induced by a methionine-choline deficient diet in mice. | 2014 | Details |
A21960 | 24930437 | Liver Int | Keratins 8 and 18 are type II acute-phase responsive genes overexpressed in human liver disease. | 2014 | Details |
A21967 | 24927058 | Expert Rev Mol Diagn | Plasma high mobility group box 1 protein reflects fibrosis in pediatric nonalcoholic fatty liver disease. | 2014 | Details |
A21971 | 24923704 | Liver Int | High prevalence of non-alcoholic fatty liver disease in the Chinese - results from the Hong Kong liver health census. | 2014 | Details |
A21980 | 24917551 | Gut | Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis. | 2014 | Details |
A21982 | 24916329 | J Magn Reson Imaging | Phagocytic function of Kupffer cells in mouse nonalcoholic fatty liver disease models: Evaluation with superparamagnetic iron oxide. | 2014 | Details |
A21992 | 24905085 | Liver Int | Renin-angiotensin system and fibrosis in non-alcoholic fatty liver disease. | 2014 | Details |
A21998 | 24901254 | PLoS One | Cholesterol-induced non-alcoholic fatty liver disease and atherosclerosis aggravated by systemic inflammation. | 2014 | Details |
A22005 | 24898917 | Histopathology | Hepatocellular carcinoma with steatohepatitic features: a clinicopathological study of Japanese patients. | 2014 | Details |
A22006 | 24897026 | Int J Mol Sci | Steatosis and steatohepatitis: complex disorders. | 2014 | Details |
A22012 | 24890441 | Am J Gastroenterol | Nonalcoholic fatty liver disease is underrecognized in the primary care setting. | 2014 | Details |
A22018 | 24884574 | BMC Gastroenterol | Fast food diet with CCl4 micro-dose induced hepatic-fibrosis--a novel animal model. | 2014 | Details |
A22025 | 24868324 | World J Hepatol | Metabolic syndrome and non-alcoholic fatty liver disease in liver surgery: The new scourges? | 2014 | Details |