Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Fructose1035 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A15524 | 28862329 | J Sci Food Agric | Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats. | 2017 | Details |
| A15617 | 28805745 | Children (Basel) | Insulin Resistance and NAFLD: A Dangerous Liaison beyond the Genetics. | 2017 | Details |
| A15655 | 28781602 | Nutr Metab (Lond) | eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet. | 2017 | Details |
| A15669 | 28775179 | BMJ Open | Health and economic benefits of reducing sugar intake in the USA, including effects via non-alcoholic fatty liver disease: a microsimulation model. | 2017 | Details |
| A15736 | 28737568 | J Pediatr Gastroenterol Nutr | Systematic Review: Nutrition and Physical Activity in the Management of Paediatric Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A15865 | 28676973 | Eur J Nutr | Chronic consumption of fructose in combination with trans fatty acids but not with saturated fatty acids induces nonalcoholic steatohepatitis with fibrosis in rats. | 2017 | Details |
| A15956 | 28637520 | Br J Nutr | Citrulline decreases hepatic endotoxin-induced injury in fructose-induced non-alcoholic liver disease: an ex vivo study in the isolated perfused rat liver. | 2017 | Details |
| A15972 | 28632197 | Nutrients | Toxic AGE (TAGE) Theory for the Pathophysiology of the Onset/Progression of NAFLD and ALD. | 2017 | Details |
| A15978 | 28628909 | J Nutr Biochem | Nonalcoholic fatty liver disease impairs the cytochrome P-450-dependent metabolism of α-tocopherol (vitamin E). | 2017 | Details |
| A15981 | 28628039 | J Clin Invest | ChREBP refines the hepatic response to fructose to protect the liver from injury. | 2017 | Details |
| A15985 | 28626963 | Exp Physiol | Exercise training modulates the hepatic renin-angiotensin system in fructose-fed rats. | 2017 | Details |
| A16062 | 28587208 | Mar Drugs | Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models. | 2017 | Details |
| A16081 | 28579536 | Gastroenterology | Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity. | 2017 | Details |
| A16152 | 28536120 | FASEB J | Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor. | 2017 | Details |
| A16162 | 28529733 | Biomed Rep | Metabolic effects of Crocus sativus and protective action against non-alcoholic fatty liver disease in diabetic rats. | 2017 | Details |
| A16186 | 28511733 | Nutr Res Rev | Similarities and interactions between the ageing process and high chronic intake of added sugars. | 2017 | Details |
| A16256 | 28482789 | Curr Med Chem | Short-term Dietary Interventions for the Management of Nonalcoholic Fatty Liver. | 2019 | Details |
| A16290 | 28470676 | Hepatology | Acetyl-coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double-blind, crossover study. | 2017 | Details |
| A16300 | 28468951 | Clin Sci (Lond) | Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease. | 2017 | Details |
| A16305 | 28468010 | Dig Dis | Nutrition and Liver Health. | 2017 | Details |
| A16315 | 28463404 | Mol Nutr Food Res | A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota. | 2017 | Details |
| A16369 | 28434046 | Amino Acids | Oral arginine supplementation protects female mice from the onset of non-alcoholic steatohepatitis. | 2017 | Details |
| A16466 | 28371239 | Liver Int | The Mediterranean dietary pattern as the diet of choice for non-alcoholic fatty liver disease: Evidence and plausible mechanisms. | 2017 | Details |
| A16487 | 28359088 | Endocrinology | Sex Hormone-Binding Globulin Reduction in Metabolic Disorders May Play a Role in NAFLD Development. | 2017 | Details |
| A16496 | 28355557 | Cell Rep | Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet. | 2017 | Details |
| A16518 | 28344991 | Mol Ther Methods Clin Dev | Antibody-Directed Glucocorticoid Targeting to CD163 in M2-type Macrophages Attenuates Fructose-Induced Liver Inflammatory Changes. | 2016 | Details |
| A16577 | 28298270 | Adv Nutr | Nutritional Approaches to Achieve Weight Loss in Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16622 | 28278289 | PLoS One | Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice. | 2017 | Details |
| A16633 | 28273805 | Nutrients | Fructose and NAFLD: The Multifaceted Aspects of  Fructose Metabolism. | 2017 | Details |
| A16636 | 28271632 | IUBMB Life | The role of insufficient copper in lipid synthesis and fatty-liver disease. | 2017 | Details |
| A16659 | 28260070 | Int J Mol Med | A long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, as a preventive drug for the development of hepatic steatosis in high-fructose diet-fed ob/ob mice. | 2017 | Details |
| A16661 | 28257781 | Food Chem Toxicol | Diet high in fructose promotes liver steatosis and hepatocyte apoptosis in C57BL/6J female mice: Role of disturbed lipid homeostasis and increased oxidative stress. | 2017 | Details |
| A16706 | 28232454 | Am J Physiol Gastrointest Liver Physiol | A longitudinal study of whole body, tissue, and cellular physiology in a mouse model of fibrosing NASH with high fidelity to the human condition. | 2017 | Details |
| A16741 | 28214020 | J Hepatol | Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents. | 2017 | Details |
| A16751 | 28210913 | Int Urol Nephrol | Dietary and commercialized fructose: Sweet or sour? | 2017 | Details |
| A16753 | 28209193 | BMC Complement Altern Med | UP601, a standardized botanical composition composed of Morus alba, Yerba mate and Magnolia officinalis for weight loss. | 2017 | Details |
| A16758 | 28202906 | Sci Rep | BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis. | 2017 | Details |
| A16772 | 28189916 | J Nutr Biochem | Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver. | 2017 | Details |
| A16815 | 28157387 | Can J Physiol Pharmacol | Trigonelline attenuates hepatic complications and molecular alterations in high-fat high-fructose diet-induced insulin resistance in rats. | 2016 | Details |
| A16825 | 28146130 | Nutrients | Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD). | 2017 | Details |
| A16857 | 28124507 | Obesity (Silver Spring) | Fatty liver promotes fibrosis in monkeys consuming high fructose. | 2017 | Details |
| A16863 | 28123933 | Mol Metab | A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism. | 2016 | Details |
| A16876 | 28115523 | J Biol Chem | APOC3 Protein Is Not a Predisposing Factor for Fat-induced Nonalcoholic Fatty Liver Disease in Mice. | 2017 | Details |
| A16978 | 28067024 | Mol Nutr Food Res | Treatment with alpha-galactosylceramide protects mice from early onset of nonalcoholic steatohepatitis: Role of intestinal barrier function. | 2017 | Details |
| A17022 | 28039158 | Am J Physiol Gastrointest Liver Physiol | Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis. | 2016 | Details |
| A17041 | 28034722 | Brain Res | Specific regions of the brain are capable of fructose metabolism. | 2016 | Details |
| A17053 | 28027586 | Hepatology | Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis. | 2017 | Details |
| A17078 | 28003715 | J Clin Exp Hepatol | High-Fructose Intake Impairs the Hepatic Hypolipidemic Effects of a High-Fat Fish-Oil Diet in C57BL/6 Mice. | 2016 | Details |
| A17096 | 27995280 | Arch Toxicol | Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A17108 | 27988847 | Eur J Nutr | Calcium and vitamin D3 combinations improve fatty liver disease through AMPK-independent mechanisms. | 2016 | Details |
| A17126 | 27978932 | Zhonghua Gan Zang Bing Za Zhi | [Preventive and therapeutic effects of compound ginkgo extract in rats with nonalcoholic steatohepatitis induced by high-fat, high-fructose diet]. | 2016 | Details |
| A17130 | 27974597 | Nutr Rev | What is the appropriate upper limit for added sugars consumption? | 2017 | Details |
| A17158 | 27941940 | Nutr Diabetes | Kefir peptides prevent high-fructose corn syrup-induced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway. | 2016 | Details |
| A17178 | 27928909 | Proteomics | Using proteomics to discover novel biomarkers for fatty liver development and response to CB1R antagonist treatment in an obese mouse model. | 2017 | Details |
| A17213 | 27910784 | Int J Med Mushrooms | Hepatoprotective Effect of Tricholoma giganteum (Agaricomycetes) in a Nonalcoholic Fatty Liver Disease Rat Model. | 2016 | Details |
| A17239 | 27895389 | J Clin Biochem Nutr | Comparisons of dietary intake in Japanese with non-alcoholic fatty liver disease and type 2 diabetes mellitus. | 2016 | Details |
| A17268 | 27876107 | Br J Nutr | Sodium butyrate protects mice from the development of the early signs of non-alcoholic fatty liver disease: role of melatonin and lipid peroxidation. | 2016 | Details |
| A17271 | 27874078 | Sci Rep | Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice. | 2016 | Details |
| A17282 | 27863346 | J Nutr Biochem | A diet-induced Sprague-Dawley rat model of nonalcoholic steatohepatitis-related cirrhosis. | 2016 | Details |
| A17353 | 27827899 | Nutrients | Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: Current Understanding. | 2016 | Details |
| A17360 | 27824430 | Drug Res (Stuttg) | Dietary Fructose-Induced Hepatic Injury in Male and Female Rats: Influence of Resveratrol. | 2016 | Details |
| A17488 | 27768909 | J Nutr Biochem | High-fructose corn syrup-55 consumption alters hepatic lipid metabolism and promotes triglyceride accumulation. | 2016 | Details |
| A17542 | 27752492 | Prev Nutr Food Sci | Carrot Juice Administration Decreases Liver Stearoyl-CoA Desaturase 1 and Improves Docosahexaenoic Acid Levels, but Not Steatosis in High Fructose Diet-Fed Weanling Wistar Rats. | 2016 | Details |
| A17543 | 27752155 | Beijing Da Xue Xue Bao Yi Xue Ban | [Nicotine alleviates the liver inflammation of non-alcoholic steatohepatitis induced by high-fat and high-fructose in mice]. | 2016 | Details |
| A17547 | 27572941 | Dig Dis Sci | Diet-Induced Nonalcoholic Fatty Liver Disease Is Associated with Sarcopenia and Decreased Serum Insulin-Like Growth Factor-1. | 2016 | Details |
| A17635 | 27697525 | Biochem Biophys Res Commun | Long-term fructose consumption prolongs hepatic stearoyl-CoA desaturase 1 activity independent of upstream regulation in rats. | 2016 | Details |
| A17670 | 27672297 | World J Gastroenterol | Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease. | 2016 | Details |
| A17683 | 27660122 | Diabetes Care | Fatty Liver and Chronic Kidney Disease: Novel Mechanistic Insights and Therapeutic Opportunities. | 2016 | Details |
| A17687 | 27658772 | Gastroenterology | Estrogen Signals Through Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease. | 2016 | Details |
| A17712 | 27640119 | Lipids Health Dis | Clinical assessment of hepatic de novo lipogenesis in non-alcoholic fatty liver disease. | 2016 | Details |
| A17732 | 27632911 | Nutr Res | Cynanchum wilfordii Radix attenuates liver fat accumulation and damage by suppressing hepatic cyclooxygenase-2 and mitogen-activated protein kinase in mice fed with a high-fat and high-fructose diet. | 2016 | Details |
| A17797 | 27581063 | Clin Gastroenterol Hepatol | Nonobese Fatty Liver Disease. | 2016 | Details |
| A17812 | 27565159 | Eat Weight Disord | Beverage consumption and paediatric NAFLD. | 2016 | Details |
| A17856 | 27522101 | Drug Metab Pers Ther | Altered pharmacokinetics of rosiglitazone in a mouse model of non-alcoholic fatty liver disease. | 2016 | Details |
| A17948 | 27458503 | World J Hepatol | Lipogenesis in Huh7 cells is promoted by increasing the fructose: Glucose molar ratio. | 2016 | Details |
| A17974 | 27442361 | J Pediatr Endocrinol Metab | Dietary fructose intake in obese children and adolescents: relation to procollagen type III N-terminal peptide (P3NP) and non-alcoholic fatty liver disease. | 2016 | Details |
| A18010 | 27418186 | Eur J Nutr | Sugars, obesity, and cardiovascular disease: results from recent randomized control trials. | 2016 | Details |
| A18011 | 27417700 | J Sci Food Agric | Carrot juice ingestion attenuates high fructose-induced circulatory pro-inflammatory mediators in weanling Wistar rats. | 2016 | Details |
| A18030 | 27404046 | J Gastroenterol Hepatol | Loss of lipopolysaccharide-binding protein attenuates the development of diet-induced non-alcoholic fatty liver disease in mice. | 2017 | Details |
| A18041 | 27391242 | PLoS One | An Animal Model for the Juvenile Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. | 2016 | Details |
| A18048 | 27384305 | Endocrinology | Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18069 | 27372863 | Med Hypotheses | Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance. | 2016 | Details |
| A18070 | 27371158 | Exp Cell Res | Role of antigen presenting cell invariant chain in the development of hepatic steatosis in mouse model. | 2016 | Details |
| A18083 | 27357269 | Mol Med Rep | Impact of activating transcription factor 4 signaling on lipogenesis in HepG2 cells. | 2016 | Details |
| A18104 | 27349927 | Sci Rep | CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18120 | 27342212 | Gastroenterology | Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol. | 2016 | Details |
| A18136 | 27326314 | World J Hepatol | Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy. | 2016 | Details |
| A18141 | 27323620 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Effect of Compound Zhajin Granule on Toll-like Receptor 4 Signaling Pathway in Nonalcoholic Steatohepatitis Mice]. | 2016 | Details |
| A18152 | 27318147 | Gastroenterology | Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients. | 2016 | Details |
| A18213 | 27281105 | Medicine (Baltimore) | Nonalcoholic fatty liver disease is associated with excessive calorie intake rather than a distinctive dietary pattern. | 2016 | Details |
| A18258 | 27261415 | J Hepatol | A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer. | 2016 | Details |
| A18276 | 27248435 | Curr Protoc Mouse Biol | Development of a Representative Mouse Model with Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18288 | 27239734 | Lab Invest | C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis. | 2016 | Details |
| A18336 | 27197843 | Br J Nutr | Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats. | 2016 | Details |
| A18421 | 27146014 | Annu Rev Nutr | Hormonal and Metabolite Regulation of Hepatic Glucokinase. | 2016 | Details |
| A18430 | 27142744 | J Nutr Biochem | Liquid fructose in pregnancy exacerbates fructose-induced dyslipidemia in adult female offspring. | 2016 | Details |
| A18501 | 27089331 | Int J Mol Sci | NAFLD and Chronic Kidney Disease. | 2016 | Details |
| A18540 | 27063273 | Clin Liver Dis | Effect of Weight Loss, Diet, Exercise, and Bariatric Surgery on Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18638 | 27019761 | Scientifica (Cairo) | A High-Fat, High-Fructose Diet Induces Antioxidant Imbalance and Increases the Risk and Progression of Nonalcoholic Fatty Liver Disease in Mice. | 2016 | Details |
| A18679 | 27001641 | Int J Obes (Lond) | Sweeteners and health: findings from recent research and their impact on obesity and related metabolic conditions. | 2016 | Details |