Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24898 | 22382613 | Minerva Endocrinol | Neuroendocrine and endocrine dysfunction in the hyperinsulinemic PCOS patient: the role of metformin. | 2012 | Details |
| A24899 | 22381945 | Phytomedicine | Prevention of free fatty acid-induced lipid accumulation, oxidative stress, and cell death in primary hepatocyte cultures by a Gynostemma pentaphyllum extract. | 2012 | Details |
| A24900 | 22380754 | BMC Gastroenterol | Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24904 | 22375522 | Expert Rev Gastroenterol Hepatol | Nonalcoholic fatty liver disease and bariatric surgery. | 2012 | Details |
| A24906 | 22374640 | Diabetes Care | Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
| A24910 | 22372457 | Histopathology | The epidemiology, pathogenesis and histopathology of fatty liver disease. | 2012 | Details |
| A24917 | 22363403 | PLoS One | A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease. | 2012 | Details |
| A24919 | 22360487 | Curr Med Chem | Non-alcoholic steatohepatitis: what can we learn from animal models? | 2012 | Details |
| A24922 | 22359625 | PLoS One | Liver and muscle in morbid obesity: the interplay of fatty liver and insulin resistance. | 2012 | Details |
| A24927 | 22348916 | Drugs Today (Barc) | Current therapies for nonalcoholic fatty liver disease. | 2011 | Details |
| A24928 | 22348670 | Ugeskr Laeger | [Prognosis and treatment of non-alcoholic fatty liver disease and steatohepatitis]. | 2012 | Details |
| A24932 | 22343513 | Clin Gastroenterol Hepatol | Association between puberty and features of nonalcoholic fatty liver disease. | 2012 | Details |
| A24933 | 22343419 | Free Radic Biol Med | Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. | 2012 | Details |
| A24944 | 22320918 | J Gastroenterol Hepatol | Pathophysiology guided treatment of nonalcoholic steatohepatitis. | 2012 | Details |
| A24949 | 22326764 | Clin Res Hepatol Gastroenterol | HCC and NASH: how strong is the clinical demonstration? | 2012 | Details |
| A24950 | 22326465 | J Hepatol | Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. | 2012 | Details |
| A24951 | 22326434 | Gastroenterology | Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. | 2012 | Details |
| A24954 | 22315014 | Endocrine | The role of pro/anti-inflammatory adipokines on bone metabolism in NAFLD obese adolescents: effects of long-term interdisciplinary therapy. | 2012 | Details |
| A24960 | 22310735 | J Gastroenterol | Inflammation and fibrogenesis in steatohepatitis. | 2012 | Details |
| A24961 | 22308841 | J Pediatr Endocrinol Metab | The prevalence of non-alcoholic fatty liver disease and metabolic syndrome in obese children. | 2011 | Details |
| A24964 | 22307032 | Gastroenterology | Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice. | 2012 | Details |
| A24969 | 22297300 | Am J Physiol Endocrinol Metab | Adiponectin promoter activator NP-1 reduces body weight and hepatic steatosis in high-fat diet-fed animals. | 2012 | Details |
| A24972 | 22294100 | Cell Mol Life Sci | A role for sphingolipids in the pathophysiology of obesity-induced inflammation. | 2012 | Details |
| A24982 | 22280920 | Physiol Behav | Non-alcoholic fatty liver disease impairs hippocampal-dependent memory in male rats. | 2012 | Details |
| A24984 | 22278337 | Diabetologia | Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials. | 2012 | Details |
| A24987 | 22275361 | J Biol Chem | Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. | 2012 | Details |
| A24988 | 22274553 | Acta Diabetol | Factors that influence basal insulin requirement in type 2 diabetes. | 2012 | Details |
| A24994 | 22269154 | Gene | Association of adiponectin gene functional polymorphisms (-11377C/G and +45T/G) with nonalcoholic fatty liver disease. | 2011 | Details |
| A24995 | 22268100 | Am J Physiol Gastrointest Liver Physiol | Consumption of a high-fat diet rapidly exacerbates the development of fatty liver disease that occurs with chronically elevated glucocorticoids. | 2012 | Details |
| A24997 | 22265683 | Dig Liver Dis | Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property. | 2012 | Details |
| A25008 | 22249092 | Saudi J Gastroenterol | The association of metabolic syndrome, insulin resistance and non-alcoholic fatty liver disease in overweight/obese children. | 2012 | Details |
| A25011 | 22237875 | JPEN J Parenter Enteral Nutr | Nonalcoholic fatty liver disease in pediatric patients. | 2012 | Details |
| A25015 | 22246329 | Eur J Gastroenterol Hepatol | The association between adipocytokines and biomarkers for nonalcoholic fatty liver disease-induced liver injury: a study in the general population. | 2012 | Details |
| A25017 | 22245895 | J Hepatol | Predictors for incidence and remission of NAFLD in the general population during a seven-year prospective follow-up. | 2012 | Details |
| A25018 | 22242926 | Metab Syndr Relat Disord | Docosahexaenoic acid prevents trans-10, cis-12-conjugated linoleic acid-induced nonalcoholic fatty liver disease in mice by altering expression of hepatic genes regulating fatty acid synthesis and oxidation. | 2012 | Details |
| A25023 | 22239625 | Curr Vasc Pharmacol | Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options. | 2012 | Details |
| A25025 | 22238690 | PLoS One | Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver. | 2012 | Details |
| A25026 | 22236001 | Clin Exp Immunol | Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells. | 2012 | Details |
| A25030 | 22229957 | Int J Food Sci Nutr | Serum vitamin B12 and folate levels in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A25031 | 22228717 | Diabetes | TIMP3 overexpression in macrophages protects from insulin resistance, adipose inflammation, and nonalcoholic fatty liver disease in mice. | 2012 | Details |
| A25034 | 22227333 | Eur J Pharmacol | Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models. | 2011 | Details |
| A25037 | 22227046 | Arch Med Res | Human immunodeficiency virus is the major determinant of steatosis and hepatitis C virus of insulin resistance in virus-associated fatty liver disease. | 2012 | Details |
| A25038 | 22224077 | Hepat Mon | Obesity and air pollution: global risk factors for pediatric non-alcoholic fatty liver disease. | 2011 | Details |
| A25040 | 22221818 | Liver Int | The potential role of prebiotic fibre for treatment and management of non-alcoholic fatty liver disease and associated obesity and insulin resistance. | 2011 | Details |
| A25042 | 22221448 | Lipids Health Dis | Dietary restriction, caloric value and the accumulation of hepatic fat. | 2012 | Details |
| A25044 | 22221215 | Nutr Rev | Therapeutic potential of green tea in nonalcoholic fatty liver disease. | 2012 | Details |
| A25045 | 22219597 | World J Gastroenterol | Serum Bcl-2 concentrations in overweight-obese subjects with nonalcoholic fatty liver disease. | 2011 | Details |
| A25048 | 22215535 | IUBMB Life | Association of nonalcoholic fatty liver disease with a single nucleotide polymorphism on the gene encoding leptin receptor. | 2012 | Details |
| A25051 | 22213086 | Hepatology | Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease. | 2012 | Details |
| A25056 | 33907358 | J Proteomics Bioinform | High Fat Diet-Induced Changes in Hepatic Protein Abundance in Mice. | 2012 | Details |
| A25061 | 24713801 | Ann Gastroenterol | Non-alcoholic fatty liver disease may develop in individuals with normal body mass index. | 2012 | Details |
| A25062 | 24436572 | Curr Trends Endocinol | Fatty acid metabolism and thyroid hormones. | 2012 | Details |
| A25066 | 23750438 | Przegl Lek | [Nonalcoholic fatty liver disease as a risk factor of macroangiopahty in patients with type 2 diabetes]. | 2012 | Details |
| A25067 | 22201932 | Front Biosci (Elite Ed) | Influence of lifestyle habits, nutritional status and insulin resistance in NAFLD. | 2012 | Details |
| A25070 | 22197629 | Dig Liver Dis | Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. | 2011 | Details |
| A25071 | 22196506 | J Acupunct Meridian Stud | Ayurvedic formulation of Liv-Pro-08 reduces nonalcoholic fatty liver disease in rats fed with high-fat diet. | 2011 | Details |
| A25072 | 22194737 | Exp Diabetes Res | The role of metformin in the management of NAFLD. | 2011 | Details |
| A25073 | 22190925 | Int J Endocrinol | Intrauterine growth retardation and nonalcoholic Fatty liver disease in children. | 2011 | Details |
| A25075 | 22189171 | Diabetes Res Clin Pract | Elevated asymmetric dimethylarginine in plasma: an early marker for endothelial dysfunction in non-alcoholic fatty liver disease? | 2011 | Details |
| A25078 | 22187656 | J Lipids | Non-alcoholic Fatty liver disease: the bile Acid-activated farnesoid x receptor as an emerging treatment target. | 2011 | Details |
| A25082 | 22183953 | Hepatology | Hepatic endothelin-1 and endocannabinoids-dependent effects of hyperleptinemia in nonalcoholic steatohepatitis-cirrhotic rats. | 2012 | Details |
| A25085 | 22183820 | Dig Dis Sci | Prevalence of hypothyroidism in nonalcoholic fatty liver disease. | 2011 | Details |
| A25086 | 22183689 | Hepatology | Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A25087 | 22183113 | Curr Opin Infect Dis | From nonalcoholic fatty liver to nonalcoholic steatohepatitis and cirrhosis in HIV-infected patients: diagnosis and management. | 2012 | Details |
| A25088 | 22182810 | Dis Markers | SREBP-2 1784 G/C genotype is associated with non-alcoholic fatty liver disease in north Indians. | 2011 | Details |
| A25090 | 22181832 | Intern Med J | Relationship between non-alcoholic fatty liver disease and pulmonary function. | 2012 | Details |
| A25093 | 22179204 | Mol Med Rep | Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism. | 2011 | Details |
| A25094 | 22176347 | Hepatol Res | High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism. | 2011 | Details |
| A25097 | 22173246 | Singapore Med J | Metabolic syndrome. | 2011 | Details |
| A25098 | 22173168 | J Hepatol | The interaction of hepatic lipid and glucose metabolism in liver diseases. | 2011 | Details |
| A25100 | 22173165 | J Hepatol | Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. | 2011 | Details |
| A25101 | 22170794 | Eur J Endocrinol | Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies. | 2011 | Details |
| A25103 | 22168074 | Eksp Klin Gastroenterol | [Elastography efficiency in the liver fibrosis determination in patients with nonalcoholic fatty liver disease]. | 2011 | Details |
| A25109 | 22166563 | Ann Hepatol | Serum homocysteine levels in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A25113 | 22160635 | Dig Dis Sci | Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD. | 2011 | Details |
| A25116 | 22157234 | Eur J Gastroenterol Hepatol | Serum concentrations of human insulin-like growth factor-1 and levels of insulin-like growth factor-binding protein-5 in patients with nonalcoholic fatty liver disease: association with liver histology. | 2012 | Details |
| A25133 | 22152320 | Zhonghua Gan Zang Bing Za Zhi | [Effects of telmisartan on nonalcoholic steatohepatitis rat model by activating peroxisome proliferator-activated receptor r]. | 2011 | Details |
| A25134 | 22152305 | Cell Metab | Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease. | 2011 | Details |
| A25139 | 22149546 | Diabetes Technol Ther | Inflammatory markers in relation to nonalcoholic fatty liver disease in urban South Indians. | 2011 | Details |
| A25140 | 22147010 | Endocrinology | Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance. | 2011 | Details |
| A25141 | 22143620 | Int J Obes (Lond) | Hepatic left lobe volume is a sensitive index of metabolic improvement in obese women after gastric banding. | 2011 | Details |
| A25143 | 22141340 | J Gastroenterol Hepatol | Genetic variation in PNPLA3 but not APOC3 influences liver fat in non-alcoholic fatty liver disease. | 2012 | Details |
| A25153 | 22132232 | PLoS One | Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells. | 2011 | Details |
| A25157 | 22126026 | Adv Clin Chem | Iron overload in nonalcoholic steatohepatitis. | 2011 | Details |
| A25159 | 22125617 | PLoS One | Coordinated defects in hepatic long chain fatty acid metabolism and triglyceride accumulation contribute to insulin resistance in non-human primates. | 2011 | Details |
| A25160 | 22124850 | Curr Gastroenterol Rep | Iron metabolism in Nonalcoholic Fatty Liver Disease. | 2012 | Details |
| A25161 | 22122481 | Curr Pharm Biotechnol | Non-alcoholic steatohepatitis: new insights from OMICS studies. | 2012 | Details |
| A25163 | 24843533 | J Diabetes Investig | Impact of glucose tolerance on the severity of non-alcoholic steatohepatitis. | 2011 | Details |
| A25170 | 22117531 | Aliment Pharmacol Ther | Visceral adiposity index is associated with significant fibrosis in patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25171 | 22115060 | BMC Res Notes | Non-alcoholic fatty liver disease in a rural, physically active, low income population in Sri Lanka. | 2011 | Details |
| A25178 | 22110478 | Exp Diabetes Res | Role of transcription factor modifications in the pathogenesis of insulin resistance. | 2011 | Details |
| A25185 | 22108448 | Am J Gastroenterol | Ultrasonographically detected non-alcoholic fatty liver disease is an independent predictor for identifying patients with insulin resistance in non-obese, non-diabetic middle-aged Asian adults. | 2011 | Details |
| A25192 | 22103042 | Acta Gastroenterol Belg | Lean non-alcoholic fatty liver disease (Lean-NAFLD): a major cause of cryptogenic liver disease. | 2011 | Details |
| A25197 | 22098614 | Liver Int | Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients. | 2011 | Details |
| A25203 | 22096112 | Eur J Endocrinol | Recent advances in cardiovascular aspects of polycystic ovary syndrome. | 2011 | Details |
| A25205 | 22095588 | Hepatology | Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease. | 2012 | Details |
| A25208 | 22093607 | Gastroenterol Hepatol | Genetic factors associated with the presence and progression of nonalcoholic fatty liver disease: a narrative review. | 2011 | Details |
| A25219 | 22087124 | Hepat Mon | Rosuvastatin reduces nonalcoholic fatty liver disease in patients with chronic hepatitis C treated with α-interferon and ribavirin: Rosuvastatin reduces NAFLD in HCV patients. | 2011 | Details |
| A25221 | 22082482 | Curr Mol Med | The emerging role of endocrine disruptors in pathogenesis of insulin resistance: a concept implicating nonalcoholic fatty liver disease. | 2012 | Details |
| A25223 | 22082204 | Diabetol Metab Syndr | L-carnitine ameliorated fatty liver in high-calorie diet/STZ-induced type 2 diabetic mice by improving mitochondrial function. | 2011 | Details |