Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A22026 | 24868321 | World J Hepatol | Gender and racial differences in nonalcoholic fatty liver disease. | 2014 | Details |
A22030 | 24866317 | Rev Med Inst Mex Seguro Soc | [Nonalcoholic fatty liver disease in children]. | 2014 | Details |
A22031 | 24865256 | Dig Dis Sci | Tauroursodeoxycholic acid attenuates progression of steatohepatitis in mice fed a methionine-choline-deficient diet. | 2014 | Details |
A22036 | 24861026 | J Mol Med (Berl) | NLRP3 inflammasome activation is required for fibrosis development in NAFLD. | 2014 | Details |
A22038 | 24858832 | PLoS One | β-Cryptoxanthin alleviates diet-induced nonalcoholic steatohepatitis by suppressing inflammatory gene expression in mice. | 2014 | Details |
A22039 | 24857839 | Arch Biochem Biophys | Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis. | 2014 | Details |
A22045 | 24853141 | PLoS One | HCC development is associated to peripheral insulin resistance in a mouse model of NASH. | 2014 | Details |
A22048 | 24851523 | Trop Gastroenterol | Profile of patients with incidentally detected nonalcoholic fatty liver disease (IDNAFLD) in coastal eastern India. | 2014 | Details |
A22053 | 24849310 | Hepatology | Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity. | 2014 | Details |
A22061 | 24845607 | J Hepatol | Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice. | 2014 | Details |
A22069 | 24842304 | J Hepatol | Homozygous MTTP and APOB mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia. | 2014 | Details |
A22071 | 24841950 | Obes Surg | The diagnostic accuracy of transient elastography for the diagnosis of liver fibrosis in bariatric surgery candidates with suspected NAFLD. | 2014 | Details |
A22074 | 24837835 | Int J Mol Sci | Role of mitochondria in nonalcoholic fatty liver disease. | 2014 | Details |
A22075 | 24837195 | Clin Exp Pharmacol Physiol | Non-alcoholic fatty liver disease (NAFLD) fibrosis score predicts 6.6-year overall mortality of Chinese patients with NAFLD. | 2014 | Details |
A22076 | 24836834 | Transplant Proc | Nonalcoholic Fatty liver disease in renal transplant recipients proven by transient elastography. | 2014 | Details |
A22083 | 24830559 | Int J Mol Sci | Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation. | 2014 | Details |
A22088 | 24829682 | Middle East J Dig Dis | Probiotics and Nonalcoholic Fatty liver Disease. | 2013 | Details |
A22089 | 24829591 | Hepat Mon | Nonalcoholic Fatty liver disease/non-alcoholic steatohepatitis in childhood: endocrine-metabolic "mal-programming". | 2014 | Details |
A22093 | 24827629 | Gut Liver | Gallstone disease does not predict liver histology in nonalcoholic fatty liver disease. | 2014 | Details |
A22104 | 24818764 | Gastroenterology | No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial. | 2014 | Details |
A22117 | 24803983 | Oxid Med Cell Longev | BL153 partially prevents high-fat diet induced liver damage probably via inhibition of lipid accumulation, inflammation, and oxidative stress. | 2014 | Details |
A22119 | 24802098 | Mamm Genome | Modeling progressive non-alcoholic fatty liver disease in the laboratory mouse. | 2014 | Details |
A22122 | 24799988 | World J Hepatol | Insulin sensitizers for the treatment of non-alcoholic fatty liver disease. | 2014 | Details |
A22126 | 24798049 | Liver Int | The combination of liver stiffness measurement and NAFLD fibrosis score improves the noninvasive diagnostic accuracy for severe liver fibrosis in patients with nonalcoholic fatty liver disease. | 2014 | Details |
A22127 | 24797980 | Adv Med Sci | Serum fetuin A concentration is elevated in children with non-alcoholic fatty liver disease. | 2014 | Details |
A22132 | 24796231 | Hepatol Res | Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J). | 2014 | Details |
A22135 | 24795720 | Front Immunol | Role of innate immune response in non-alcoholic Fatty liver disease: metabolic complications and therapeutic tools. | 2014 | Details |
A22138 | 24795036 | Dig Dis Sci | Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet-induced NASH model. | 2014 | Details |
A22144 | 24791845 | Med Ultrason | Ultrasound screening for hepatocellular carcinoma in patients with advanced liver fibrosis. An overview. | 2014 | Details |
A22145 | 24791843 | Med Ultrason | Comparison between the M and XL probes for liver fibrosis assessment by transient elastography. | 2014 | Details |
A22149 | 24786317 | Exp Cell Res | Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model. | 2014 | Details |
A22151 | 24786095 | Int J Mol Sci | Molecular mechanisms and new treatment strategies for non-alcoholic steatohepatitis (NASH). | 2014 | Details |
A22155 | 24783906 | Med Arch | Anthropometric and biochemical characteristics of patients with nonalcoholic fatty liver diagnosed by non-invasive diagnostic methods. | 2014 | Details |
A22157 | 24782622 | World J Gastroenterol | Controlled attenuation parameter for non-invasive assessment of hepatic steatosis in Chinese patients. | 2014 | Details |
A22158 | 24782263 | Semin Liver Dis | Hepatic pathology among patients without known liver disease undergoing bariatric surgery: observations and a perspective from the longitudinal assessment of bariatric surgery (LABS) study. | 2014 | Details |
A22160 | 24781986 | PLoS One | Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice. | 2014 | Details |
A22162 | 24777953 | Hepatology | Relationship between disease severity, hyperinsulinemia, and impaired insulin clearance in patients with nonalcoholic steatohepatitis. | 2014 | Details |
A22173 | 24768810 | Clin Gastroenterol Hepatol | Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies. | 2014 | Details |
A22181 | 24764670 | World J Gastroenterol | Pediatric non-alcoholic steatohepatitis: the first report on the ultrastructure of hepatocyte mitochondria. | 2014 | Details |
A22183 | 24763757 | PLoS One | Risk of obstructive sleep apnea with daytime sleepiness is associated with liver damage in non-morbidly obese patients with nonalcoholic fatty liver disease. | 2014 | Details |
A22184 | 24761121 | Pharmacognosy Res | Pioglitazone, quercetin and hydroxy citric acid effect on hepatic biomarkers in Non Alcoholic Steatohepatitis. | 2014 | Details |
A22187 | 24759667 | Gastroenterol Rep (Oxf) | Wedge and needle liver biopsies show discordant histopathology in morbidly obese patients undergoing Roux-en-Y gastric bypass surgery. | 2013 | Details |
A22188 | 24759663 | Gastroenterol Rep (Oxf) | Update of liver fibrosis and steatosis with transient elastography (Fibroscan). | 2013 | Details |
A22190 | 24758559 | Biochem J | Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice. | 2014 | Details |
A22199 | 24753132 | Hepatology | Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the evaluation of biopsies of nonalcoholic fatty liver disease. | 2014 | Details |
A22202 | 24750664 | Liver Int | The pan-caspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis. | 2014 | Details |
A22204 | 24750217 | J Gastroenterol Hepatol | Serum proteome of nonalcoholic fatty liver disease: a multimodal approach to discovery of biomarkers of nonalcoholic steatohepatitis. | 2014 | Details |
A22210 | 24747563 | Biochem Biophys Res Commun | Bile acids override steatosis in farnesoid X receptor deficient mice in a model of non-alcoholic steatohepatitis. | 2014 | Details |
A22213 | 24746708 | Gastroenterol Hepatol | [Non-invasive markers of fibrosis in the diagnosis of non-alcoholic fatty liver disease]. | 2014 | Details |
A22217 | 24743702 | PLoS One | Genome-wide analysis of copy number variation identifies candidate gene loci associated with the progression of non-alcoholic fatty liver disease. | 2014 | Details |
A22218 | 24743504 | Eur J Gastroenterol Hepatol | Pentoxifylline for the treatment of nonalcoholic fatty liver disease: a meta-analysis of randomized double-blind, placebo-controlled studies. | 2014 | Details |
A22227 | 24739055 | Clin Exp Pharmacol Physiol | Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice. | 2014 | Details |
A22231 | 24737902 | Postgrad Med J | Republished: Non-alcoholic fatty liver disease: non-invasive investigation and risk stratification. | 2014 | Details |
A22239 | 24731656 | Lancet Diabetes Endocrinol | Effects of iron overload on chronic metabolic diseases. | 2013 | Details |
A22240 | 24730643 | J Gastroenterol Hepatol | Neonatal monosodium glutamate treatment causes obesity, diabetes, and macrovesicular steatohepatitis with liver nodules in DIAR mice. | 2014 | Details |
A22244 | 24726273 | Clin Res Hepatol Gastroenterol | Pediatric non-alcoholic fatty liver disease: recent advances. | 2014 | Details |
A22254 | 24716593 | BMC Gastroenterol | Expression of energy metabolism related genes in the gastric tissue of obese individuals with non-alcoholic fatty liver disease. | 2014 | Details |
A22271 | 24702768 | FEBS J | Revisiting the metabolic syndrome and paving the way for microRNAs in non-alcoholic fatty liver disease. | 2014 | Details |
A22291 | 24689101 | J Gastrointestin Liver Dis | Recreational drugs: a new health hazard for patients with concomitant chronic liver diseases. | 2014 | Details |
A22298 | 24684403 | Liver Int | Adipocytokine expression associated with miRNA regulation and diagnosis of NASH in obese patients with NAFLD. | 2014 | Details |
A22305 | 26202505 | Hepatol Int | Value of shear wave velocity measurements for the risk assessment of hepatocellular carcinoma development in patients with nonalcoholic fatty liver disease : HCC risk assessment by VTTQ. | 2014 | Details |
A22306 | 24677740 | Pediatr Obes | Prevalence and outcome of non-alcoholic fatty liver disease in adolescents and young adults undergoing weight loss surgery. | 2014 | Details |
A22313 | 24671009 | Curr Opin Gastroenterol | Current status of fibrosis markers. | 2014 | Details |
A22314 | 24670599 | Hum Mol Genet | PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells. | 2014 | Details |
A22317 | 24668763 | Hepatology | Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice. | 2014 | Details |
A22323 | 24661406 | Hepatol Res | Diagnosis and classification of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Current concepts and remaining challenges. | 2014 | Details |
A22328 | 24657400 | J Hepatol | Procoagulant imbalance in patients with non-alcoholic fatty liver disease. | 2014 | Details |
A22330 | 24656139 | Nutr Metab Cardiovasc Dis | Lipid and liver abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes. | 2014 | Details |
A22336 | 24652022 | Wien Klin Wochenschr | Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease. | 2014 | Details |
A22338 | 24651825 | J Antimicrob Chemother | Maraviroc, a CCR5 antagonist, ameliorates the development of hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD). | 2014 | Details |
A22339 | 24651520 | PLoS One | Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli sand rat). | 2014 | Details |
A22342 | 24650559 | Am J Pathol | Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle. | 2014 | Details |
A22346 | 24649857 | Liver Int | Hepatic toll-like receptor 4 expression is associated with portal inflammation and fibrosis in patients with NAFLD. | 2014 | Details |
A22350 | 24646400 | Scand J Gastroenterol | Nonalcoholic fatty liver disease and cholesterol gallstones: which comes first? | 2014 | Details |
A22362 | 24637477 | PLoS One | Non-invasive assessment of hepatic steatosis in patients with NAFLD using controlled attenuation parameter and 1H-MR spectroscopy. | 2014 | Details |
A22374 | 24632764 | Minerva Gastroenterol Dietol | Recommendations for liver biopsy evaluation in non-alcoholic fatty liver disease. | 2014 | Details |
A22376 | 24631029 | Dig Liver Dis | Intestinal permeability is increased in children with non-alcoholic fatty liver disease, and correlates with liver disease severity. | 2014 | Details |
A22382 | 24628836 | Liver Int | n-3 polyunsaturated fatty acids worsen inflammation and fibrosis in experimental nonalcoholic steatohepatitis. | 2014 | Details |
A22383 | 24628717 | Hepatol Res | Clinical usage of serum ferritin to assess liver fibrosis in patients with non-alcoholic fatty liver disease: Proceed with caution. | 2014 | Details |
A22390 | 24626178 | Cell Cycle | Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease. | 2014 | Details |
A22395 | 24621583 | J Hum Genet | Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease. | 2014 | Details |
A22396 | 24621397 | Liver Int | Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-alcoholic steatohepatitis (NASH)? | 2014 | Details |
A22400 | 24616207 | Obesity (Silver Spring) | Macrophages and fibrosis in adipose tissue are linked to liver damage and metabolic risk in obese children. | 2014 | Details |
A22405 | 24608579 | Minerva Pediatr | Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in Albanian overweight children. | 2014 | Details |
A22406 | 24607626 | J Hepatol | Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma. | 2014 | Details |
A22408 | 24607243 | J Pediatr | Insulin-like growth factor-I and -II levels are associated with the progression of nonalcoholic fatty liver disease in obese children. | 2014 | Details |
A22414 | 24602757 | J Diabetes Complications | Not only type 2 diabetes but also prediabetes is associated with portal inflammation and fibrosis in patients with non-alcoholic fatty liver disease. | 2014 | Details |
A22422 | 24588719 | J Med Food | A dietary restriction influences the progression but not the initiation of MSG-Induced nonalcoholic steatohepatitis. | 2014 | Details |
A22429 | 24587650 | World J Gastroenterol | Clinical approaches to non-alcoholic fatty liver disease. | 2014 | Details |
A22433 | 24581591 | Clin Res Hepatol Gastroenterol | Non-cirrhotic portal hypertension--concept, diagnosis and clinical management. | 2014 | Details |
A22435 | 24579874 | Clin Transplant | Histologically proven non-alcoholic fatty liver disease and clinically related factors in recipients after liver transplantation. | 2014 | Details |
A22439 | 24577062 | J Appl Physiol (1985) | Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats. | 2014 | Details |
A22440 | 24576046 | Radiology | Noninvasive differentiation of simple steatosis and steatohepatitis by using gadoxetic acid-enhanced MR imaging in patients with nonalcoholic fatty liver disease: a proof-of-concept study. | 2014 | Details |
A22442 | 24575585 | Osaka City Med J | Histologically proven hepatocellular carcinoma associated with burned-out nonalcoholic steatohepatitis. | 2013 | Details |
A22443 | 24574727 | World J Gastroenterol | Effects of pentoxifylline on nonalcoholic fatty liver disease: a meta-analysis. | 2014 | Details |
A22444 | 24574716 | World J Gastroenterol | Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2014 | Details |
A22452 | 24559185 | BMC Gastroenterol | The relationship between hepatic resistin overexpression and inflammation in patients with nonalcoholic steatohepatitis. | 2014 | Details |
A22455 | 24556343 | Contemp Clin Trials | Design and rationale of the WELCOME trial: A randomised, placebo controlled study to test the efficacy of purified long chainomega-3 fatty acid treatment in non-alcoholic fatty liver disease [corrected]. | 2014 | Details |
A22460 | 24552673 | J Pediatr Gastroenterol Nutr | Shear wave elastography in the evaluation of liver fibrosis in children. | 2014 | Details |
A22478 | 24528633 | J Dig Dis | The relationship between advanced oxidation protein products (AOPP) and biochemical and histopathological findings in patients with nonalcoholic steatohepatitis. | 2014 | Details |